Vitamin D 3-inducible mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growth

Molecular Pharmaceutics

Volumn 9, Issue 5, 2012, Pages 1396-1408

  Hsiao, Wan Chi ^a   Sung, Shian Ying ^a,c   Liao, Chia Hui ^c   Wu, Hsi Chin ^b,c   Hsieh, Chia Ling ^a,c,d  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d ASIA UNIVERSITY   (Taiwan)

Author keywords

bone marrow derived mesenchymal stem cells; human osteocalcin promoter; inducible cell based gene delivery; renal cell carcinoma; vitamin D 3

Indexed keywords

ADENOVIRUS HUMAN OSTEOCALCIN GLYCOPROTEIN E1; ADENOVIRUS VECTOR; COLECALCIFEROL; GLYCOPROTEIN E1; ONCOLYTIC ADENOVIRUS; OSTEOCALCIN; PLATELET DERIVED GROWTH FACTOR AA; UNCLASSIFIED DRUG; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR A; PLATELET-DERIVED GROWTH FACTOR A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CANCER INHIBITION; CANCER REGRESSION; CELL MIGRATION; COCULTURE; CONTROLLED STUDY; CYTOTOXICITY; FLUORESCENCE IMAGING; GENE DELIVERY SYSTEM; GENE THERAPY; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; MALE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN SECRETION; VIRUS REPLICATION; ADENOVIRUS; ANIMAL; BAGG ALBINO MOUSE; CYTOLOGY; DRUG EFFECT; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; IMMUNOHISTOCHEMISTRY; MESENCHYMAL STROMA CELL; METABOLISM; METHODOLOGY; NUDE MOUSE; ONCOLYTIC VIROTHERAPY;

ADENOVIRIDAE; ANIMALS; CARCINOMA, RENAL CELL; CHOLECALCIFEROL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; ONCOLYTIC VIROTHERAPY; OSTEOCALCIN; PLATELET-DERIVED GROWTH FACTOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84860783872     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200649g     Document Type: Article

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