Regulation of murine hepatic hydroxysteroid sulfotransferase expression in hyposulfatemic mice and in a cell model of 39-phosphoadenosine-59-phosphosulfate deficiencys

Drug Metabolism and Disposition

Volumn 41, Issue 8, 2013, Pages 1505-1513

  Barrett, Kathleen G ^a   Fang, Hailin ^a   Gargano, Mary D ^a   Markovich, Daniel ^b   Kocarek, Thomas A ^a   Runge Morris, Melissa ^a  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

3' PHOSPHOADENOSINE 5' PHOSPHOSULFATE SYNTHASE 1; 3' PHOSPHOADENOSINE 5' PHOSPHOSULFATE SYNTHASE 2; ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; CELL NUCLEUS RECEPTOR; FARNESOID X RECEPTOR; HYDROXYSTEROID SULFOTRANSFERASE; MESSENGER RNA; PREGNANE X RECEPTOR; RETINOID RELATED ORPHAN RECEPTOR; SULFOTRANSFERASE; SULFOTRANSFERASE 2A1; SYNTHETASE; UNCLASSIFIED DRUG;

ABNORMALLY LOW SUBSTRATE CONCENTRATION IN BLOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENE MUTATION; GENE SILENCING; HYPOSULFATEMIA; INVERTED REPEAT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MOTIF; REPORTER GENE; TRANSCRIPTION INITIATION; WILD TYPE;

ANIMALS; CATION TRANSPORT PROTEINS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEP G2 CELLS; HUMANS; LIVER; MICE; MULTIENZYME COMPLEXES; PHOSPHOADENOSINE PHOSPHOSULFATE; PROMOTER REGIONS, GENETIC; SULFATE ADENYLYLTRANSFERASE; SULFATES; SULFOTRANSFERASES; SYMPORTERS;

EID: 84880690576     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.113.051912     Document Type: Article

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