Transcriptional profile reveals altered hepatic lipid and cholesterol metabolism in hyposulfatemic NaS1 null mice

Physiological Genomics

Volumn 26, Issue 2, 2006, Pages 116-124

  Dawson, Paul Anthony ^a   Gardiner, Brooke ^a   Grimmond, Sean ^a   Markovich, Daniel ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Gene expression; Liver; Slc13a1; Sulfate; Transporter

Indexed keywords

CHOLESTEROL; COTRANSPORTER; LIPID; MESSENGER RNA; METALLOTHIONEIN I; PROTEIN NAS 1; SODIUM SULFATE; SULFOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DNA MICROARRAY; DOWN REGULATION; GENE EXPRESSION; GLYCOGEN LIVER LEVEL; HEPATOMEGALY; IMMUNE RESPONSE; KNOCKOUT MOUSE; LIPID LIVER LEVEL; LIPID METABOLISM; LIVER DISEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALIA;

EID: 33745934034     PISSN: 10948341     EISSN: 15312267     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00300.2005     Document Type: Article

References (56)

1. Akhtar RA, Reddy AB, Maywood ES, Clayton JD, King VM, Smith AG, Gant TW, Hastings MH, and Kyriacou CP. Circadian cycling of the mouse liver transcriptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol 12: 540-550, 2002.
2. Beck L and Markovich D. The mouse Na(+)-sulfate cotransporter gene Nas1. Cloning, tissue distribution, gene structure, chromosomal assignment, and transcriptional regulation by vitamin D. J Biol Chem 275: 11880-11890, 2000.
3. Blanchard RL, Freimuth RR, Buck J, Weinshilboum RM, and Coughtrie MW. A proposed nomenclature system for the cytosolic sulfotransferase (SULT) superfamily. Pharmacogenetics 14: 199-211, 2004.
4. Boylston WH, Gerstner A, DeFord JH, Madsen M, Flurkey K, Harrison DE, and Papaconstantinou J. Altered cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1dw/dwJ) mice. Aging Cell 3: 283-296, 2004.
5. Breslow JL. Transgenic mouse models of lipoprotein metabolism and atherosclerosis. Proc Natl Acad Sci USA 90: 8314-8318, 1993.
6. Cachefo A, Boucher P, Dusserre E, Bouletreau P, Beylot M, and Chambrier C. Stimulation of cholesterol synthesis and hepatic lipogenesis in patients with severe malabsorption. J Lipid Res 44: 1349-1354, 2003.
7. Cao SX, Dhahbi JM, Mote PL, and Spindler SR. Genomic profiling of short- and long-term caloric restriction effects in the liver of aging mice. Proc Natl Acad Sci USA 98: 10630-10635, 2001.
8. Cappiello M, Franchi M, Rane A, and Pacifici GM. Sulphotransferase and its substrate: adenosine-3′-phosphate-5′-phosphosulphate in human fetal liver and placenta. Dev Pharmacol Ther 14: 62-65, 1990.
9. Castro RE, Sola S, Ma X, Ramalho RM, Kren BT, Steer CJ, and Rodrigues CM. A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid. J Hepatol 42: 897-906, 2005.
10. Challen GA, Martinez G, Davis MJ, Taylor DF, Crowe M, Teasdale RD, Grimmond SM, and Little MH. Identifying the molecular pheno-type of renal progenitor cells. J Am Soc Nephrol 15: 2344-2357, 2004.
11. Charlton MR. Protein metabolism and liver disease. Baillieres Clin Endocrinol Metab 10: 617-635, 1996.
12. Cole DE and Scriver CR. Age-dependent serum sulfate levels in children and adolescents. Clin Chim Acta 107: 135-139, 1980.
13. Coulouarn C, Lefebvre G, Derambure C, Lequerre T, Scotte M, Francois A, Cellier D, Daveau M, and Salier JP. Altered gene expression in acute systemic inflammation detected by complete coverage of the human liver transcriptome. Hepatology 39: 353-364, 2004.
14. Coyle P, Philcox JC, Carey LC, and Rofe AM. Metallothionein: the multipurpose protein. Cell Mol Life Sci 59: 627-647, 2002.
15. Dasu MR, Cobb JP, Laramie JM, Chung TP, Spies M, and Barrow RE. Gene expression profiles of livers from thermally injured rats. Gene 327: 51-60, 2004.
16. i-1 gene. Proc Natl Acad Sci USA 100: 13704-13709, 2003.
17. De Fabiani E, Mitro N, Godio C, Gilardi F, Caruso D, and Crestani M. Bile acid signaling to the nucleus: finding new connections in the transcriptional regulation of metabolic pathways. Biochimie 86: 771-778, 2004.
18. Dhahbi JM, Kim HJ, Mote PL, Beaver RJ, and Spindler SR. Temporal linkage between the phenotypic and genomic responses to caloric restriction. Proc Natl Acad Sci USA 101: 5524-5529, 2004.
19. Endo Y, Fu Z, Abe K, Arai S, and Kato H. Dietary protein quantity and quality affect rat hepatic gene expression. J Nutr 132: 3632-3637, 2002.
20. Falany CN. Enzymology of human cytosolic sulfotransferases. FASEB J 11: 206-216, 1997.
21. Feng X, Jiang Y, Meltzer P, and Yen PM. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Mol Endocrinol 14: 947-955, 2000.
22. Feng X, Jiang Y, Meltzer P, and Yen PM. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Mol Endocrinol 14: 947-955, 2000.
23. Folch J, Lees M, and Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-505, 1957.
24. Gadacz TR, Allan RN, Mack E, and Hofmann AF. Impaired lithocholate sulfation in the rhesus monkey: a possible mechanism for chenodeoxycholate toxicity. Gastroenterology 70: 1125-1129, 1976.
25. Harada K, Ohba K, Ozaki S, Isse K, Hirayama T, Wada A, and Nakanuma Y. Peptide antibiotic human beta-defensin-1 and -2 contribute to antimicrobial defense of the intrahepatic biliary tree. Hepatology 40: 925-932, 2004.
26. Hastbacka J, de la Chapelle A, Mahtani MM, Clines G, Reeve-Daly MP, Daly M, Hamilton BA, Kusumi K, Trivedi B, Weaver A, Coloma A, Lovett M, Buckler A, Kaitila I, and Lander ES. The diastrophic dysplasia gene encodes a novel sulfate transporter: positional cloning by fine-structure linkage disequilibrium mapping. Cell 78: 1073-1087, 1994.
27. Heafield M, Fearn S, Steventon G, Waring R, Williams A, and Sturman S. Plasma cysteine and sulphate levels in patients with motor neurone, Parkinson's and Alzheimer's disease. Neurosci Lett 110: 216-220, 1990.
28. Higami Y, Weindruch R, Prolla TA, and Shimokawa I. Altered lipid metabolism in rodents subjected to calorie restriction. Geriatrics Gerontol Int 4: S155-S157, 2004.
29. Hindmarsh KW, Mayers DJ, Wallace SM, Danilkewich A, and Ernst A. Increased serum sulfate concentrations in man due to environmental factors: effects on acetaminophen metabolism. Vet Hum Toxicol 33: 441-445, 1991.
30. Ishibashi S, Brown MS, Goldstein JL, Gerard RD, Hammer RE, and Herz J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest 92: 883-893, 1993.
31. Ishibashi S, Goldstein JL, Brown MS, Herz J, and Burns DK. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest 93: 1885-1893, 1994.
32. Kim MS, Shigenaga J, Moser A, Grunfeld C, and Feingold KR. Suppression of DHEA sulfotransferase (Sult2A1) during the acute-phase response. Am J Physiol Endocrinol Metab 287: E731-E738, 2004.
33. Labrie F, Belanger A, Cusan L, Gomez JL, and Candas B. Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging. J Clin Endocrinol Metab 82: 2396-2402, 1997.
34. Lee A, Beck L, and Markovich D. The human renal sodium sulfate cotransporter (SLC13A1; hNaSi-1) cDNA and gene: organisation, chromosomal localization, and functional characterization. Genomics 70: 354-363, 2000.
35. Lee A, Beck L, and Markovich D. The mouse sulfate anion transporter gene Sat1 (Slc26a1): cloning, tissue distribution, gene structure, functional characterization, and transcriptional regulation thyroid hormone. DNA Cell Biol 22: 19-31, 2003.
36. Lee A, Dawson PA, and Markovich D. NaSi-1 and Sat-1: structure, function and transcriptional regulation of two genes encoding renal proximal tubular sulfate transporters. Int J Biochem Cell Biol 37: 1350-1356, 2005.
37. Lo S, Russell JC, and Taylor AW. Determination of glycogen in small tissue samples. J Appl Physiol 28: 234-236, 1970.
38. Markovich D. Physiological roles and regulation of mammalian sulfate transporters. Physiol Rev 81: 1499-1534, 2001.
39. McFadden SA. Phenotypic variation in xenobiotic metabolism and adverse environmental response: focus on sulfur-dependent detoxification pathways. Toxicology 111: 43-65, 1996.
40. Mulder GJ and Jakoby WB. Sulfation. In: Conjugation Reactions in Drug Metabolism: An Integrated Approach. Substrates, Co-substrates, Enzymes and Their Interactions In Vivo and In Vitro, edited by Mulder GJ. London: Taylor and Francis, 1990, p. 107-161.
41. Murer H, Markovich D, and Biber J. Renal and small intestinal sodium-dependent symporters of phosphate and sulphate. J Exp Biol 196: 167-181, 1994.
42. Ostrow JD. Metabolism of bile salts in cholestasis in humans. In: Hepatic Transport and Bile Secretion, edited by Tavoloni N and Berk PD. New York: Raven, 1993, p. 673-712.
43. Phan J, Pesaran T, Davis RC, and Reue K. The Diet1 locus confers protection against hypercholesterolemia through enhanced bile acid metabolism. J Biol Chem 277: 469-477, 2002.
44. Pratt DS. Cholestasis and cholestatic syndromes. Curr Opin Gastroenterol 21: 270-274, 2005.
45. Price VF and Jollow DJ. Effects of sulfur-amino acid-deficient diets on acetaminophen metabolism and hepatotoxicity in rats. Toxicol Appl Pharmacol 101: 356-369, 1989.
46. Qian YM, Sun XJ, Tong MH, Li XP, Richa J, and Song WC. Targeted disruption of the mouse estrogen sulfotransferase gene reveals a role of estrogen metabolism in intracrine and paracrine estrogen regulation. Endocrinology 142: 5342-5350, 2001.
47. Rowland JE, Lichanska AM, Kerr LM, White M, d'Aniello EM, Maher SL, Brown R, Teasdale RD, Noakes PG, and Waters MJ. In vivo analysis of growth hormone receptor signaling domains and their associated transcripts. Mol Cell Biol 25: 66-77, 2005.
48. Russell DW and Setchell KD. Bile acid biosynthesis. Biochemistry 31: 4737-4749, 1992.
49. Schweinfest C, Henderson K, Suster S, Kondoh N, and Papas T. Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas. Proc Natl Acad Sci USA 90: 4166-4170, 1993.
50. Smyth GK and Speed T. Normalization of cDNA microarray data. Methods 31: 265-273, 2003.
51. Stoughton RB. Applications of DNA microarrays in biology. Annu Rev Biochem 74: 53-82, 2005.
52. Strott CA. Sulfonation and molecular action. Endocr Rev 23: 703-732, 2002.
53. Tong MH, Jiang H, Liu P, Lawson JA, Brass LF, and Song WC. Spontaneous fetal loss caused by placental thrombosis in estrogen sulfotransferase-deficient mice. Nat Med 11: 153-159, 2005.
54. Vergnes L, Phan J, Strauss M, Tafuri S, and Reue K. Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression. J Biol Chem 278: 42774-42784, 2003.
55. Waring RH, Ngong JM, Klovrza LV, Green S, and Sharp H. Biochemical parameters in autistic children. Dev Brain Dysfunct 10: 40-43, 1997.
56. Zangar RC and Novak RF. Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes. Arch Biochem Biophys 337: 217-224, 1997.