Squalestatin 1-inducible expression of rat CYP2B: Evidence that an endogenous isoprenoid is an activator of the constitutive androstane receptor

Molecular Pharmacology

Volumn 62, Issue 5, 2002, Pages 1177-1186

  Kocarek, Thomas A ^a   Mercer Haines, Nancy A ^a  

^a Inst of Environ Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANE RECEPTOR; CIPROFIBRATE; CYTOCHROME P450 2B; FARNESOL; HORMONE RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ISOPRENOID; LUCIFERASE; MESSENGER RNA; MEVALONIC ACID; PHENOBARBITAL; PRAVASTATIN; SQ 34919; STEROL REGULATORY ELEMENT BINDING PROTEIN; UNCLASSIFIED DRUG; ZARAGOZIC ACID A;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; ENZYME INDUCTION; FEMALE; GENE EXPRESSION REGULATION; HORMONE RECEPTOR INTERACTION; LIVER CELL; MALE; NONHUMAN; PLASMID; PRIORITY JOURNAL; RAT; REPORTER GENE; SEX DIFFERENCE; STEROL SYNTHESIS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CELLS, CULTURED; CYTOCHROME P-450 CYP2B1; FARNESYL-DIPHOSPHATE FARNESYLTRANSFERASE; GENE EXPRESSION; HEPATOCYTES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION FACTORS; TRICARBOXYLIC ACIDS;

EID: 0036840528     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.62.5.1177     Document Type: Article

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