The CASR gene: Alternative splicing and transcriptional control, and calcium-sensing receptor (CaSR) protein: Structure and ligand binding sites

Best Practice and Research: Clinical Endocrinology and Metabolism

Volumn 27, Issue 3, 2013, Pages 285-301

  Hendy, Geoffrey N ^a,b   Canaff, Lucie ^a   Cole, David E C ^c  

^a ROYAL VICTORIA HOSPITAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

1 ,25 dihydroxyvitamin D; alternative splicing; calcium sensing receptor; Class C G protein coupled receptor; glial cells missing 2; ligand binding; nine cysteines domain; proinflammatory cytokines; seven transmembrane domain; transcription; Venus flytrap domain

Indexed keywords

AMINO ACID; ASPARAGINE; CALCITRIOL; CALCIUM SENSING RECEPTOR; CYSTEINE; CYTOKINE; G PROTEIN COUPLED RECEPTOR; HOMODIMER; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MESSENGER RNA; MONOMER; RHODOPSIN;

5' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; BINDING SITE; BURN; CARCINOGENESIS; COLON CARCINOMA; CONFERENCE PAPER; CRITICALLY ILL PATIENT; CYTOKINE RELEASE; DIMERIZATION; EXON; FAMILIAL ISOLATED HYPOPARATHYROIDISM; GENE ACTIVITY; GENE EXPRESSION; GENE LINKAGE DISEQUILIBRIUM; GENE STRUCTURE; GLIA CELL; HINGE REGION; HUMAN; HYPERCALCIURIA; HYPOPARATHYROIDISM; KERATINOCYTE; LIGAND BINDING; MISSENSE MUTATION; MUTAGENESIS; NONHUMAN; PARATHYROID ADENOMA; PATHOGENESIS; PRIMARY HYPERPARATHYROIDISM; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN STRUCTURE; SEPSIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; TATA BOX; TRANSCRIPTION REGULATION; VITAMIN D RESPONSIVE ELEMENT;

1Α,25-DIHYDROXYVITAMIN D; ALTERNATIVE SPLICING; CALCIUM-SENSING RECEPTOR; CLASS C G PROTEIN-COUPLED RECEPTOR; GLIAL CELLS MISSING-2; LIGAND BINDING; NINE-CYSTEINES DOMAIN; PROINFLAMMATORY CYTOKINES; SEVEN-TRANSMEMBRANE DOMAIN; TRANSCRIPTION; VENUS-FLYTRAP DOMAIN;

ALTERNATIVE SPLICING; BINDING SITES; CALCIUM; GENE EXPRESSION REGULATION; HUMANS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, CALCIUM-SENSING; TRANSCRIPTION, GENETIC;

EID: 84880323835     PISSN: 1521690X     EISSN: 15321908     Source Type: Journal    
DOI: 10.1016/j.beem.2013.02.009     Document Type: Conference Paper

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