Amino Acids in the Cytoplasmic C Terminus of the Parathyroid Ca 2+-sensing Receptor Mediate Efficient Cell-surface Expression and Phospholipase C Activation

Journal of Biological Chemistry

Volumn 276, Issue 47, 2001, Pages 44129-44136

  Chang, Wenhan ^b   Pratt, Stacy ^b   Chen, Tsui Hua ^b   Bourguignon, Lilly ^b   Shoback, Dolores ^a  

^a SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CELLS; CYTOLOGY; IMMUNOLOGY; MOLECULAR STRUCTURE; MUTAGENESIS; REDUCTION;

DESENSITIZATION; LIGANDS;

BIOCHEMISTRY;

ALANINE; AMINO ACID; CALCIUM; CALCIUM SENSING RECEPTOR; COMPLEMENTARY DNA; HISTIDINE; INOSITOL PHOSPHATE; PHENYLALANINE; PHOSPHOLIPASE C; SERINE; VALINE; CELL SURFACE RECEPTOR;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DESENSITIZATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GENETIC TRANSFECTION; GLYCOSYLATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MOLECULAR MODEL; MUTAGENESIS; NONHUMAN; PARATHYROID GLAND; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; CATTLE; CELL LINE; CELL MEMBRANE; CHEMISTRY; CYTOPLASM; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY;

BOVINAE;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BASE SEQUENCE; CATTLE; CELL LINE; CELL MEMBRANE; CYTOPLASM; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; PHOSPHOLIPASE C; RECEPTORS, CALCIUM-SENSING; RECEPTORS, CELL SURFACE; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION;

EID: 0035941276     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104834200     Document Type: Article

References (31)

1. Brown, E. M., Gamba, G., Riccardi, D., Lombardi, M., Butters, R., Kifor, O., Sun, A., Hediger, M. A., Lytton, J., and Hebert, S. C. (1993) Nature 366, 575-580
2. Ye, C., Kanazirska, M., Quinn, S., Brown, E. M., and Vassilev, P. M. (1996) Biochem. Biophys. Res. Commun. 224, 271-280
3. Chang, W., Pratt, S., Chen, T.-H., Nemeth, E., Huang, Z., and Shoback, D. (1998) J. Bone Miner. Res. 13, 570-580
4. Chang, W., Chen, T. H., Pratt, S., and Shoback, D. (1998) Am. J. Physiol. 275, E213-E221
5. Gomeza, J., Joly, C., Kuhn, R., Knopfel, T., Bockaert, J., and Pin, J. P. (1996) J. Biol. Chem. 271, 2199-2205
6. Flor, P. J., Gomeza, J., Tones, M. A., Kuhn, R., Pin, J. P., and Knopfel, T. (1996) J. Neurochem. 67, 58-63
7. Kaupmann, K., Huggel, K., Heid, J., Flor, P. J., Bischoff, S., Mickel, S. J., McMaster, G., Angst, C., Bittiger, H., Froestl, W., and Bettler, B. (1997) Nature 386, 239-246
8. Ryba, N. J., and Tirindelli, R. (1997) Neuron 19, 371-379
9. Cao, Y., Oh, B. C., and Stryer, L. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 11987-11992
10. Brown, E. M., Bai, M., and Pollak, M. (1998) in Metabolic Bone Disease (Avioli, L. V., and Krane, S. M., eds) pp. 479-499, Academic Press, New York
11. Chang, W., Chen, T.-H., Pratt, S. A., and Shoback, D. (2000) J. Biol. Chem. 275, 19955-19963
12. Ray, K., Fan, G. F., Goldsmith, P. K., and Spiegel, A. M. (1997) J. Biol. Chem. 272, 31355-31361
13. Bai, M., Janicic, N., Trivedi, S., Quinn, S. J., Cole, D. E., Brown, E. M., and Hendy, G. N. (1997) J. Clin. Invest. 99, 1917-1925
14. Gama, L., and Breitwieser, G. E. (1998) J. Biol. Chem. 273, 29712-29718
15. Carling, T., Szabo, E., Bai, M., Ridefelt, P., Westin, G., Gustavsson, P., Trivedi, S., Hellman, P., Brown, E. M., Dahl, N., and Rastad, J. (2000) J. Clin. Endocrinol. & Metab. 85, 2042-2047
16. Lienhardt, A., Garabedian, M., Bai, M., Sinding, C., Zhang, Z., Lagarde, J. P., Boulesteix, J., Rigaud, M., Brown, E. M., and Kottler, M. L. (2000) J. Clin. Endocrinol. & Metab. 85, 1695-1702
17. Bourguignon, L. Y., Lokeshwar, V. B., Chen, X., and Kerrick, W. G. (1993) J. Immunol. 151, 6634-6644
18. Iida, N., and Bourguignon, L. Y. (1995) J. Cell. Physiol. 162, 127-133
19. Chang, W., Tu, C., Bajra, R., Komuves, L., Miller, S., Strewler, G., and Shoback, D. (1999) Endocrinology 140, 1911-1919
20. Chang, W., Pratt, S., Chen, T. H., and Shoback, D. (1999) Mol. Cell. Endocrinol. 158, 13-23
21. Shoback, D. M., and McGhee, J. M. (1988) Endocrinology 122, 2833-2839
22. Chang, W., Tu, C., Chen, T. H., Komuves, L., Oda, Y., Pratt, S. A., Miller, S., and Shoback, D. (1999) Endocrinology 140, 5883-5893
23. Bai, M., Quinn, S., Trivedi, S., Kifor, O., Pearce, S. H. S., Pollak, M. R., Krapcho, K., Hebert, S. C., and Brown, E. M. (1996) J. Biol. Chem. 271, 19537-19545
24. Fan, G., Goldsmith, P. K., Collins, R., Dunn, C. K., Krapcho, K. J., Rogers, K. V., and Spiegel, A. M. (1997) Endocrinology 138, 1916-1922
25. Haas, I. G. (1994) Experientia (Basel) 50, 1012-1020
26. Kassenbrock, C. K., Garcia, P. D., Walter, P., and Kelly, R. B. (1988) Nature 333, 90-93
27. Lauffer, L., Garcia, P. D., Harkins, R. N., Coussens, L., Ullrich, A., and Walter, P. (1985) Nature 318, 334-338
28. Munro, S., and Pelham, H. R. (1987) Cell 48, 899-907
29. Munro, S., and Pelham, H. R. (1986) Cell 46, 291-300
30. Kozutsumi, Y., Segal, M., Normington, K., Gething, M. J., and Sambrook, J. (1988) Nature 332, 462-464
31. Chou, P. Y., and Fasman, G. D. (1978) Adv. Enzymol. 47, 45-148