The Venus's-flytrap and Cysteine-rich Domains of the Human Ca2+ Receptor are Not Linked by Disulfide Bonds

Journal of Biological Chemistry

Volumn 276, Issue 10, 2001, Pages 6901-6904

  Hu, Jianxin ^a   Reyes Cruz, Guadalupe ^b   Goldsmith, Paul K ^b   Spiegel, Allen M ^b  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; DIMERS; POSITIVE IONS; VIRUSES;

SIGNAL TRANSMISSION;

PROTEINS;

CALCIUM RECEPTOR; CYSTEINE; G PROTEIN COUPLED RECEPTOR; PROTEINASE; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; DISULFIDE; GLUTAMIC ACID; SIGNAL PEPTIDE; TEV PROTEASE; VALINE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CONTROLLED STUDY; DIMERIZATION; DISULFIDE BOND; HUMAN; HUMAN CELL; PLANT VIRUS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TOBACCO VIRUS; WESTERN BLOTTING; BINDING SITE; CELL LINE; CHEMISTRY; DOSE RESPONSE; GENETIC TRANSFECTION; IMMUNOBLOTTING; METABOLISM; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

DIONAEA; NICOTIANA TABACUM; TOBACCO ETCH VIRUS;

AMINO ACID SEQUENCE; BINDING SITES; CALCIUM-BINDING PROTEINS; CELL LINE; CYSTEINE; DIMERIZATION; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPEPTIDASES; GLUTAMIC ACID; HUMANS; IMMUNOBLOTTING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY; TRANSFECTION; VALINE;

EID: 0035831515     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C000865200     Document Type: Article

References (19)

1. Brown, E. M., Pollak, M., and Hebert, S. C. (1998) Annu. Rev. Med. 49, 15-29
2. Brown, E. M. (1999) Am. J. Med. 106, 238-253
3. Masu, M., Tanabe, Y., Tsuchida, K., Shigemoto, R., and Nakanishi, S. (1991) Nature 349, 760-765
4. Kaupmann, K., Huggel, K., Heid, J., Flor, P. J., Bischoff, S., Mickel, S. J., McMaster, G., Angst, C., Bittiger, H., Froestl, W., and Bettler, B. (1997) Nature 386, 239-246
5. Ryba, N. J. P., and Tirindelli, R. (1997) Neuron 19, 371-379
6. Hoon, M. A., Adler, E., Lindemeier, J., Batter, J. F., Ryba, N. J. P., and Zuker, C. S. (1999) Cell 96, 541-551
7. Kunishima, N., Shimada, Y., Tsuji, Y., Sato, T., Yamamoto, M., Kumasaka, T., Nakanishi, S., Jingami, H., and Morikawa, K. (2000) Nature 407, 971-977
8. Tsuji, Y., Shimada, Y., Takeshita, T. Kajimura, N., Nomura, S., Sekiyama, M., Otomo, J., Usukura, J., Nakanishi, S., and Jingami, H. (2000) J. Biol. Chem. 275, 28144-28151
9. Ray, K., Hauschild, B. C., Steinbach, P. J., Goldsmith, P. K., Hauache, O., and Spiegel, A. M. (1999) J. Biol. Chem. 274, 27642-27650
10. Fan, G. F., Ray, K., Zhao, X. M., Goldsmith, P. K., and Spiegel, A. M. (1998) FEBS Lett. 436, 353-356
11. Hu, J., Hauache, O., and Spiegel, A. M. (2000) J. Biol. Chem. 275, 16382-16389
12. Dougherty, W. G., and Semler, B. L. (1993) Microbiol. Rev. 57, 781-822
13. Ray, K., Fan, G. F., Goldsmith, P. K., and Spiegel, A. M. (1997) J. Biol. Chem. 272, 31355-31361
14. Bai, M., Quinn, S., Trivedi, S., Kifor, O., Pearce, S. H. S., Pollak, M. R., Srapcho, K., Hebert, S. C., and Brown, E. M. (1996) J. Biol. Chem. 271, 19537-19545
15. Ray, K., Clapp, P., Goldsmith, P. K., and Spiegel, A. M. (1998) J. Biol. Chem. 273, 34558-34567
16. Hammerland, L. G., Krapcho, K. J., Garrett, J. E., Alasti, N., Hung, B. C. P., Simin, R. T., Levinthal, C., Nemeth, E. F., and Fuller, F. H. (1999) Mol. Pharmacol. 77, 642-648
17. Brauner-Osborne, H., Jensen, A. A., Sheppard, P. O., O'Hara, P., and Krogsgaard-Larsen, P. (1999) J. Biol. Chem. 274, 18382-18386
18. Bockaert, J., and Pin, J. P. (1999) EMBO J. 18, 1723-1729
19. Garrett, J. E., Capuano, I. V., Hammerland, L. G., Hung, B. C. P., Brown, E. M., Hebert, S. C., Nemeth, E. F., and Fuller, F. (1995) J. Biol. Chem. 270, 12919-12925