Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 46622-46631

  Hu, Jianxin ^a,c   Reyes Cruz, Guadalupe ^a   Chen, Wangzhong ^b   Jacobson, Kenneth A ^b   Spiegel, Allen M ^a  

^a NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; SENSITIVITY ANALYSIS;

MUTATIONS;

BIOCHEMISTRY;

CALCIUM ION; CALCIUM ION RECEPTOR; G PROTEIN COUPLED RECEPTOR; N [3 (2 CHLOROPHENYL)PROPYL] 1 (3 METHOXYPHENYL)ETHYLAMINE; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID COMPOSITION; ARTICLE; CALCIUM BINDING; CALCIUM MOBILIZATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PHOSPHOINOSITIDE METABOLISM; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION;

ALANINE; ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BLOTTING, WESTERN; CALCIUM; CALCIUM-BINDING PROTEINS; CELL LINE; HUMANS; IMMUNOHISTOCHEMISTRY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED;

EID: 0037195862     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207100200     Document Type: Article

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