Regulation of renal calcium receptor gene expression by 1,25-dihydroxyvitamin D3 in genetic hypercalciuric stone-forming rats

Journal of the American Society of Nephrology

Volumn 16, Issue 5, 2005, Pages 1300-1308

  Yao, Jim J ^a   Bai, Shaochun ^a   Karnauskas, Alexander J ^a   Bushinsky, David A ^b   Favus, Murray J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITRIOL; CALCIUM ACTIVATED POTASSIUM CHANNEL; MESSENGER RNA; VITAMIN D RECEPTOR; CALCIUM; CALCIUM CHANNEL STIMULATING AGENT; CALCIUM SENSING RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM ABSORPTION; CALCIUM INTAKE; CONTROLLED STUDY; EXTRACELLULAR CALCIUM; FEMALE; GENE CONTROL; GENE EXPRESSION; HALF LIFE TIME; HYPERCALCIURIA; KIDNEY TUBULE; MALE; NEPHROLITHIASIS; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETICS; HYPERCALCEMIA; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT; URINE; UROLITHIASIS;

ANIMALS; CALCITRIOL; CALCIUM; CALCIUM CHANNEL AGONISTS; GENE EXPRESSION; HYPERCALCEMIA; KIDNEY; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CALCIUM-SENSING; RNA, MESSENGER; TRANSCRIPTION, GENETIC; URINARY CALCULI;

EID: 23944440516     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2004110991     Document Type: Article

References (46)

1. Pak CY, Britton F, Peterson R, Ward D, Northcutt C, Breslau NA, McGuire J, Sakhaee K, Bush S, Nicar M, Norman DA, Peters P: Ambulatory evaluation of nephrolithiasis: Classification, clinical presentation and diagnostic criteria. Am J Med 69: 19-30, 1980
2. Coe FL, Parks JH, Asplin JR: The pathogenesis and treatment of kidney stones. N Engl J Med 327: 1141-1152, 1992
3. Coe FL, Favus MJ, Asplin JR: Nephrolithiasis. In: The Kidney, 7th Ed., edited by Brenner BM, Philadelphia, WB Saunders, 2004, pp 1819-1866
4. Parks JH, Coward M, Coe FL: Correspondence between stone composition and urine supersaturation in nephrolithiasis. Kidney Int 51: 894-900, 1997
5. Coe FL, Parks JH: New insights into the pathophysiology and treatment of nephrolithiasis: New research venues. J Bone Miner Res 12: 522-533, 1997
6. Kaplan RA, Haussler MR, Deftos LJ, Bone H, Pak CY: The role of 1-alpha-25-dihydroxyvitamin D in the mediation of intestinal hyperabsorption of calcium in primary hyperparathyroidism and absorptive hypercalciuria. J Clin Invest 59: 756-760, 1977
7. Bushinsky DA, Grynpas MD, Nilsson EL, Nakagawa Y, Coe FL: Stone formation in genetic hypercalciuric rats. Kidney Int 48: 1705-1713, 1995
8. Bushinsky DA, Parker WR, Asplin J: Calcium phosphate supersaturation regulates stone formation in genetic hypercalciuric stone forming rats. Kidney Int 57: 550-560, 2000
9. Bushinsky DA, Grynpas MD, Asplin JR: Effect of acidosis on urine supersaturation and stone formation in genetic hypercalciuric stone forming rats. Kidney Int 59: 1415-1423, 2001
10. Bushinsky DA, Asplin JR, Grynpas MD, Evan AP, Parker WR, Alexander KM, Coe FL: Calcium oxalate stone formation in genetic hypercalciuric stone forming rats. Kidney Int 61: 975-987, 2002
11. Bushinsky DA, Favus MJ: Mechanism of hypercalciuria in genetic hypercalciuric rats. Inherited defect in intestinal calcium transport. J Clin Invest 82: 1585-1591, 1988
12. Li XQ, Tembe V, Horwitz GM, Bushinsky DA, Favus MJ: Increased intestinal vitamin D receptor in genetic hypercalciuric rats. A cause of intestinal calcium hyperabsorption. J Clin Invest 91: 661-667, 1993
13. Kim M, Sessler NE, Tembe V, Favus MJ, Bushinsky DA: Response of genetic hypercalciuric rats to a low calcium diet. Kidney Int 43: 189-196, 1993
14. 3 levels in patients with idiopathic hypercalciuria and in normal subjects. Am J Med 72: 25-32, 1982
15. Birge SJ, Peck WA, Herman M, Whedon GD: Study of calcium absorption in man. A kinetic analysis and physiologic model. J Clin Invest 48: 1705-1713, 1969
16. Pak CY, East DA, Sanzenbacher LJ, Delea CS, Bartter FC: Gastrointestinal calcium absorption in nephrolithiasis. J Clin Endocrinol Metab 35: 261-270, 1972
17. Zerwekh JE, Pak CYC: Selective effects of thiazide therapy on serum 1 alpha 25-dihydroxyvitamin D and intestinal calcium absorption in renal and absorptive hypercalciuria. Metab Clin Exp 29: 13-17, 1980
18. 3 in bone from genetic hypercalciuric rats. Am J Physiol 271: C130-C135, 1996
19. Tsuruoka S, Bushinsky DA, Schwartz GJ: Defective renal calcium reabsorption in genetic hypercalciuric rats. Kidney Int 51: 1540-1547, 1997
20. Shen FH, Baylink DJ, Nielsen RL, Sherrard DJ, Ivey JL, Haussler MR: Increased serum 1,25-dihydroxyvitamin D in idiopathic hypercalciuria. J Lab Clin Med 90: 955-962, 1977
21. Broadus AE, Insogna KL, Lang R, Ellison AF, Dreyer BE: Evidence for disordered control of 1,25-dihydroxyvitamin D production in absorptive hypercalciuria. N Engl J Med 311: 73-80, 1984
22. Insogna KL, Broadus AE, Dreyer BE, Ellison AF, Gertner JM: Elevated production rate of 1,25-dihydroxyvitamin D in patients with absorptive hypercalciuria. J Clin Endocrinol Metab 61: 490-495, 1985
23. Sutton RAL, Walker SA: Responses to hydrochlorothiazide and acetazolamide in patients with calcium stones. Evidence suggesting a defect in renal tubular function. N Engl J Med 302: 709-713, 1980
24. 3. A new characteristic of genetic hypercalciuric stone-forming rats. J Clin Invest 101: 2223-2232, 1998
25. Goodman WG: Calcium-sensing receptors. Semin Nephrol 24: 17-24, 2004
26. Brown EM, MacLeod RJ: Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 81: 239-297, 2001
27. Riccardi D, Park J, Lee WS, Gamba G, Brown EM, Hebert SC: Cloning and functional expression of a rat kidney extracellular calcium/polyvalent cation-sensing receptor. Proc Natl Acad Sci U S A 92: 131-135, 1994
28. 2 is involved in mediating the effect of extracellular Ca2+ on apical K+ channels in rat TAL. Am J Physiol 273: F421-F429, 1997
29. Wang W, Lu M, Hebert SC: Cytochrome P-450 metabolites mediate extracellular Ca(2+)-induced inhibition of apical K+ channels in the TAL. Am J Physiol 271: C103-C111, 1996
30. Yarden N, Lavelin I, Genina O, Hurwitz S, Diaz R, Brown EM, Pines M: Expression of calcium-sensing receptor gene by avian parathyroid gland in vivo: Relationship to plasma calcium. Gen Comp Endocrinol 117: 173-181, 2000
31. Bushinsky DA, Neumann K, Asplin J, Krieger NS: Alendronate decreases urine calcium and supersaturation in genetic hypercalciuric rats. Kidney Int 55: 234-243, 1999
32. Asplin JR, Bushinsky DA, Singharetnam W, Riordon D, Parks JH, Coe FL: Relationship between supersaturation and crystal inhibition in hypercalciuric rats. Kidney Int 51: 640-645, 1997
33. Bushinsky DA, Bashir MA, Riordon DR, Nakagawa Y, Coe FL, Grynpas: Increased dietary oxalate does not increase urinary calcium oxalate saturation in hypercalciuric rats. Kidney Int 55: 602-612, 1999
34. Yao J, Bone RC, Sawhney R: Differential effect of tumor necrosis factor-alpha on the expression of fibronectin and collagen genes in cultured bovine endothelial cells. Cell Mol Biol Res 41: 17-28, 1995
35. Brown AJ, Zhong M, Finch J, Ritter C, McCracken R, Morrissey J, Slatopolsky E: Rat calcium-sensing receptor is regulated by vitamin D but not by calcium. Am J Physiol 270: F454-F460, 1996
36. Yao J, Eghbali M: Decreased collagen gene expression and absence of fibrosis in thyroid hormone-induced myocardial hypertrophy: Response of cardiac fibroblasts to thyroid hormone in vitro. Circ Res 71: 831-839, 1992
37. Yao J, Giant TT, Lark MW, Mikecz K, Jacobs JJ, Hutchinson NI, Hoerrner LA, Kuettner KE, Galante JO: The potential role of fibroblasts in periprosthetic osteolysis: Fibroblast response to titanium particles. J Bone Miner Res 10: 1417-1427, 1995
38. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159, 1987
39. Favus MJ, Coe FL: Evidence for spontaneous hypercalciuria in the rat. Miner Electrolyte Metab 2: 150-154, 1979
40. Bushinsky DA, Kim M, Sessler NE, Nakagawa Y, Coe FL: Increased urinary saturation and kidney calcium content in genetic hypercalciuric rats. Kidney Int 48: 58-65, 1994
41. Karnauskas AJ, van Leeuwen JPTM, van den Bemd G-JCM, Kathpalia PP, DeLuca HF, Bushinsky DA, Favus MJ: Mechanism and function of high vitamin D receptor levels in genetic hypercalciuric stone-forming rats. J Bone Miner Res 20: 447-454, 2004
42. Canaff L, Hendy GN: Human calcium-sensing receptor gene. Vitamin D response elements in promoters P1 and P2 confer transcriptional responsiveness to 1,25-dihydroxyvitamin D. J Biol Chem 277: 30337-30350, 2002
43. 3. Endocrinology 136: 499-504, 1995
44. Riccardi D, Lee WS, Lee K, Segre GV, Brown EM, Hebert SC: Localization of the extracellular Ca(2+)-sensing receptor and PTH/PTHrP receptor in rat kidney. Am J Physiol 271: F951-F956, 1996
45. Riccardi D, Hall AE, Chattopadhyay N, Xu JZ, Brown EM, Hebert SC: Localization of the extracellular Ca(2+)/polyvalent cation-sensing protein in rat kidney. Am J Physiol 274: F611-F622, 1998
46. Motoyama HI, Friedman PA: Calcium-sensing receptor regulation of PTH-dependent calcium absorption by mouse cortical ascending limbs. Am J Physiol 283: F399-F406, 2002