The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel

Journal of Biological Chemistry

Volumn 288, Issue 25, 2013, Pages 18366-18380

  Buck, Teresa M ^a   Plavchak, Lindsay ^a   Roy, Ankita ^b   Donnelly, Bridget F ^b   Kashlan, Ossama B ^b   Kleyman, Thomas R ^b   Subramanya, Arohan R ^b,c   Brodsky, Jeffrey L ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOPLASMIC RETICULUM ASSOCIATED DEGRADATIONS; EPITHELIAL SODIUM CHANNELS; HUMAN DISEASE; NEW THERAPEUTIC AGENT; SUBSTRATE SELECTION;

BIOCHEMISTRY; BIOLOGY;

CELL MEMBRANES;

CHAPERONE; EPITHELIAL SODIUM CHANNEL; HEAT SHOCK PROTEIN 70; MUTANT PROTEIN; NUCLEOTIDE; PROTEIN GRP170; PROTEIN LHS1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CELL TYPE; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; OOCYTE; PRECIPITATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; XENOPUS; YEAST CELL;

ENAC; ENDOPLASMIC RETICULUM (ER); ER-ASSOCIATED DEGRADATION; MOLECULAR CHAPERONE; PROTEASOME; SODIUM CHANNELS;

ADENOSINE TRIPHOSPHATE; AMILORIDE; ANIMALS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM-ASSOCIATED DEGRADATION; EPITHELIAL SODIUM CHANNELS; FEMALE; GLYCOPROTEINS; HEK293 CELLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; ION TRANSPORT; MEMBRANE POTENTIALS; MUTATION; OOCYTES; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SODIUM; XENOPUS;

EID: 84880066268     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.469882     Document Type: Article

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