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Volumn 350, Issue 2, 2012, Pages 242-247

The role of the ENaC-regulatory complex in aldosterone-mediated sodium transport

Author keywords

Aldosterone signaling; ENaC regulatory complex; Scaffold protein

Indexed keywords

ALDOSTERONE; CELL PROTEIN; EPITHELIAL SODIUM CHANNEL; PROTEIN GILZ1; SODIUM; UNCLASSIFIED DRUG;

EID: 84856349666     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2011.11.003     Document Type: Review
Times cited : (48)

References (72)
  • 1
    • 0037303045 scopus 로고    scopus 로고
    • Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells
    • Alvarez de la Rosa D., Canessa C.M. Role of SGK in hormonal regulation of epithelial sodium channel in A6 cells. Am. J. Physiol. Cell Physiol. 2003, 284:C404-414.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.284
    • Alvarez de la Rosa, D.1    Canessa, C.M.2
  • 2
    • 0033621468 scopus 로고    scopus 로고
    • The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes
    • Alvarez de la Rosa D., Zhang P., Naray-Fejes-Toth A., Fejes-Toth G., Canessa C.M. The serum and glucocorticoid kinase sgk increases the abundance of epithelial sodium channels in the plasma membrane of Xenopus oocytes. J. Biol. Chem. 1999, 274:37834-37839.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37834-37839
    • Alvarez de la Rosa, D.1    Zhang, P.2    Naray-Fejes-Toth, A.3    Fejes-Toth, G.4    Canessa, C.M.5
  • 3
    • 33746658984 scopus 로고    scopus 로고
    • An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery
    • Arteaga M.F., Wang L., Ravid T., Hochstrasser M., Canessa C.M. An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc. Natl. Acad. Sci. USA 2006, 103:11178-11183.
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 11178-11183
    • Arteaga, M.F.1    Wang, L.2    Ravid, T.3    Hochstrasser, M.4    Canessa, C.M.5
  • 4
    • 22444451372 scopus 로고    scopus 로고
    • FoxO3 mediates antagonistic effects of glucocorticoids and interleukin-2 on glucocorticoid-induced leucine zipper expression
    • Asselin-Labat M.L., Biola-Vidamment A., Kerbrat S., Lombes M., Bertoglio J., Pallardy M. FoxO3 mediates antagonistic effects of glucocorticoids and interleukin-2 on glucocorticoid-induced leucine zipper expression. Mol. Endocrinol. 2005, 19:1752-1764.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 1752-1764
    • Asselin-Labat, M.L.1    Biola-Vidamment, A.2    Kerbrat, S.3    Lombes, M.4    Bertoglio, J.5    Pallardy, M.6
  • 5
    • 3042792367 scopus 로고    scopus 로고
    • GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis
    • Asselin-Labat M.L., David M., Biola-Vidamment A., Lecoeuche D., Zennaro M.C., Bertoglio J., Pallardy M. GILZ, a new target for the transcription factor FoxO3, protects T lymphocytes from interleukin-2 withdrawal-induced apoptosis. Blood 2004, 104:215-223.
    • (2004) Blood , vol.104 , pp. 215-223
    • Asselin-Labat, M.L.1    David, M.2    Biola-Vidamment, A.3    Lecoeuche, D.4    Zennaro, M.C.5    Bertoglio, J.6    Pallardy, M.7
  • 6
    • 0035437169 scopus 로고    scopus 로고
    • Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB
    • Ayroldi E., Migliorati G., Bruscoli S., Marchetti C., Zollo O., Cannarile L., D'Adamio F., Riccardi C. Modulation of T-cell activation by the glucocorticoid-induced leucine zipper factor via inhibition of nuclear factor kappaB. Blood 2001, 98:743-753.
    • (2001) Blood , vol.98 , pp. 743-753
    • Ayroldi, E.1    Migliorati, G.2    Bruscoli, S.3    Marchetti, C.4    Zollo, O.5    Cannarile, L.6    D'Adamio, F.7    Riccardi, C.8
  • 7
    • 70350534804 scopus 로고    scopus 로고
    • Glucocorticoid-induced leucine zipper (GILZ): a new important mediator of glucocorticoid action
    • Ayroldi E., Riccardi C. Glucocorticoid-induced leucine zipper (GILZ): a new important mediator of glucocorticoid action. Faseb 2009, J23:3649-3658.
    • (2009) Faseb , vol.J23 , pp. 3649-3658
    • Ayroldi, E.1    Riccardi, C.2
  • 9
    • 0036840376 scopus 로고    scopus 로고
    • Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1
    • Ayroldi E., Zollo O., Macchiarulo A., Di Marco B., Marchetti C., Riccardi C. Glucocorticoid-induced leucine zipper inhibits the Raf-extracellular signal-regulated kinase pathway by binding to Raf-1. Mol. Cell Biol. 2002, 22:7929-7941.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 7929-7941
    • Ayroldi, E.1    Zollo, O.2    Macchiarulo, A.3    Di Marco, B.4    Marchetti, C.5    Riccardi, C.6
  • 10
    • 1942518228 scopus 로고    scopus 로고
    • Mechanisms of mineralocorticoid action: determinants of receptor specificity and actions of regulated gene products
    • Bhargava A., Pearce D. Mechanisms of mineralocorticoid action: determinants of receptor specificity and actions of regulated gene products. Trends Endocrinol. Metab. 2004, 15:147-153.
    • (2004) Trends Endocrinol. Metab. , vol.15 , pp. 147-153
    • Bhargava, A.1    Pearce, D.2
  • 11
    • 2342477841 scopus 로고    scopus 로고
    • Regulation of epithelial ion transport by aldosterone through changes in gene expression
    • Bhargava A., Wang J., Pearce D. Regulation of epithelial ion transport by aldosterone through changes in gene expression. Mol. Cell. Endocrinol. 2004, 217:189-196.
    • (2004) Mol. Cell. Endocrinol. , vol.217 , pp. 189-196
    • Bhargava, A.1    Wang, J.2    Pearce, D.3
  • 12
    • 33745188921 scopus 로고    scopus 로고
    • A novel N-terminal hydrophobic motif mediates constitutive degradation of serum- and glucocorticoid-induced kinase-1 by the ubiquitin-proteasome pathway
    • Bogusz A.M., Brickley D.R., Pew T., Conzen S.D. A novel N-terminal hydrophobic motif mediates constitutive degradation of serum- and glucocorticoid-induced kinase-1 by the ubiquitin-proteasome pathway. Febs 2006, J273:2913-2928.
    • (2006) Febs , vol.J273 , pp. 2913-2928
    • Bogusz, A.M.1    Brickley, D.R.2    Pew, T.3    Conzen, S.D.4
  • 13
    • 10644290934 scopus 로고    scopus 로고
    • PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes
    • Brone B., Eggermont J. PDZ proteins retain and regulate membrane transporters in polarized epithelial cell membranes. Am. J. Physiol. Cell Physiol. 2005, 288:C20-29.
    • (2005) Am. J. Physiol. Cell Physiol. , vol.288
    • Brone, B.1    Eggermont, J.2
  • 14
    • 18044375802 scopus 로고    scopus 로고
    • Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells
    • Cao L., Owsianik G., Becq F., Nilius B. Chronic exposure to EGF affects trafficking and function of ENaC channel in cystic fibrosis cells. Biochem. Biophys. Res. Commun. 2005, 331:503-511.
    • (2005) Biochem. Biophys. Res. Commun. , vol.331 , pp. 503-511
    • Cao, L.1    Owsianik, G.2    Becq, F.3    Nilius, B.4
  • 16
    • 34248576576 scopus 로고    scopus 로고
    • KSR and CNK: two scaffolds regulating RAS-mediated RAF activation
    • Claperon A., Therrien M. KSR and CNK: two scaffolds regulating RAS-mediated RAF activation. Oncogene 2007, 26:3143-3158.
    • (2007) Oncogene , vol.26 , pp. 3143-3158
    • Claperon, A.1    Therrien, M.2
  • 19
    • 4644240440 scopus 로고    scopus 로고
    • A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit
    • Diakov A., Korbmacher C. A novel pathway of epithelial sodium channel activation involves a serum- and glucocorticoid-inducible kinase consensus motif in the C terminus of the channel's alpha-subunit. J. Biol. Chem. 2004, 279:38134-38142.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38134-38142
    • Diakov, A.1    Korbmacher, C.2
  • 22
    • 28144461773 scopus 로고    scopus 로고
    • Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells
    • Flores S.Y., Loffing-Cueni D., Kamynina E., Daidie D., Gerbex C., Chabanel S., Dudler J., Loffing J., Staub O. Aldosterone-induced serum and glucocorticoid-induced kinase 1 expression is accompanied by Nedd4-2 phosphorylation and increased Na+ transport in cortical collecting duct cells. J. Am. Soc. Nephrol. 2005, 16:2279-2287.
    • (2005) J. Am. Soc. Nephrol. , vol.16 , pp. 2279-2287
    • Flores, S.Y.1    Loffing-Cueni, D.2    Kamynina, E.3    Daidie, D.4    Gerbex, C.5    Chabanel, S.6    Dudler, J.7    Loffing, J.8    Staub, O.9
  • 23
    • 0347360288 scopus 로고    scopus 로고
    • ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells
    • Fujita H., Omori S., Ishikura K., Hida M., Awazu M. ERK and p38 mediate high-glucose-induced hypertrophy and TGF-beta expression in renal tubular cells. Am. J. Physiol. 2004, 286:F120-126.
    • (2004) Am. J. Physiol. , vol.286
    • Fujita, H.1    Omori, S.2    Ishikura, K.3    Hida, M.4    Awazu, M.5
  • 24
    • 58649092475 scopus 로고    scopus 로고
    • MTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
    • Garcia-Martinez J.M., Alessi D.R. MTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). Biochemistry 2008, J416:375-385.
    • (2008) Biochemistry , vol.J416 , pp. 375-385
    • Garcia-Martinez, J.M.1    Alessi, D.R.2
  • 25
    • 0037072892 scopus 로고    scopus 로고
    • Identification of cytoplasmic domains within the epithelial Na+ channel reactive at the plasma membrane
    • Hendron E., Patel P., Hausenfluke M., Gamper N., Shapiro M.S., Booth R.E., Stockand J.D. Identification of cytoplasmic domains within the epithelial Na+ channel reactive at the plasma membrane. J. Biol. Chem. 2002, 277:34480-34488.
    • (2002) J. Biol. Chem. , vol.277 , pp. 34480-34488
    • Hendron, E.1    Patel, P.2    Hausenfluke, M.3    Gamper, N.4    Shapiro, M.S.5    Booth, R.E.6    Stockand, J.D.7
  • 27
    • 34547177916 scopus 로고    scopus 로고
    • The integration of signaling by multiprotein complexes containing Raf kinases
    • Kyriakis J.M. The integration of signaling by multiprotein complexes containing Raf kinases. Biochim. Biophys. Acta. 2007, 1773:1238-1247.
    • (2007) Biochim. Biophys. Acta. , vol.1773 , pp. 1238-1247
    • Kyriakis, J.M.1
  • 28
    • 77954852559 scopus 로고    scopus 로고
    • The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling
    • Lim J., Zhou M., Veenstra T.D., Morrison D.K. The CNK1 scaffold binds cytohesins and promotes insulin pathway signaling. Genes Dev. 2010, 24:1496-1506.
    • (2010) Genes Dev. , vol.24 , pp. 1496-1506
    • Lim, J.1    Zhou, M.2    Veenstra, T.D.3    Morrison, D.K.4
  • 29
    • 64149085069 scopus 로고    scopus 로고
    • Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC)
    • Loffing J., Korbmacher C. Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC). Pflugers Arch. 2009, 458:111-135.
    • (2009) Pflugers Arch. , vol.458 , pp. 111-135
    • Loffing, J.1    Korbmacher, C.2
  • 33
    • 18244382092 scopus 로고    scopus 로고
    • SGK1: a rapid aldosterone-induced regulator of renal sodium reabsorption
    • (Bethesda)
    • McCormick JA, Bhalla V, Pao AC, Pearce D (2005) SGK1: a rapid aldosterone-induced regulator of renal sodium reabsorption. Physiology (Bethesda) 20: 134-139.
    • (2005) Physiology , vol.20 , pp. 134-139
    • McCormick, J.A.1    Bhalla, V.2    Pao, A.C.3    Pearce, D.4
  • 34
    • 40449098229 scopus 로고    scopus 로고
    • WNK kinases and renal sodium transport in health and disease: an integrated view
    • McCormick J.A., Yang C.L., Ellison D.H. WNK kinases and renal sodium transport in health and disease: an integrated view. Hypertension 2008, 51:588-596.
    • (2008) Hypertension , vol.51 , pp. 588-596
    • McCormick, J.A.1    Yang, C.L.2    Ellison, D.H.3
  • 35
    • 33644675944 scopus 로고    scopus 로고
    • Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism
    • Michlig S., Harris M., Loffing J., Rossier B.C., Firsov D. Progesterone down-regulates the open probability of the amiloride-sensitive epithelial sodium channel via a Nedd4-2-dependent mechanism. J. Biol. Chem. 2005, 280:38264-38270.
    • (2005) J. Biol. Chem. , vol.280 , pp. 38264-38270
    • Michlig, S.1    Harris, M.2    Loffing, J.3    Rossier, B.C.4    Firsov, D.5
  • 36
    • 0345352652 scopus 로고    scopus 로고
    • Mineralocorticoid effects in the kidney: correlation between alphaENaC, GILZ, and Sgk-1 mRNA expression and urinary excretion of Na+ and K+
    • Muller O.G., Parnova R.G., Centeno G., Rossier B.C., Firsov D., Horisberger J.D. Mineralocorticoid effects in the kidney: correlation between alphaENaC, GILZ, and Sgk-1 mRNA expression and urinary excretion of Na+ and K+. J. Am. Soc. Nephrol. 2003, 14:1107-1115.
    • (2003) J. Am. Soc. Nephrol. , vol.14 , pp. 1107-1115
    • Muller, O.G.1    Parnova, R.G.2    Centeno, G.3    Rossier, B.C.4    Firsov, D.5    Horisberger, J.D.6
  • 37
    • 0037249699 scopus 로고    scopus 로고
    • Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease
    • Nagao S., Yamaguchi T., Kusaka M., Maser R.L., Takahashi H., Cowley B.D., Grantham J.J. Renal activation of extracellular signal-regulated kinase in rats with autosomal-dominant polycystic kidney disease. Kidney Int. 2003, 63:427-437.
    • (2003) Kidney Int. , vol.63 , pp. 427-437
    • Nagao, S.1    Yamaguchi, T.2    Kusaka, M.3    Maser, R.L.4    Takahashi, H.5    Cowley, B.D.6    Grantham, J.J.7
  • 38
    • 0033546341 scopus 로고    scopus 로고
    • Sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels
    • Naray-Fejes-Toth A., Canessa C., Cleaveland E.S., Aldrich G., Fejes-Toth G. sgk is an aldosterone-induced kinase in the renal collecting duct. Effects on epithelial na+ channels. J. Biol. Chem. 1999, 274:16973-16978.
    • (1999) J. Biol. Chem. , vol.274 , pp. 16973-16978
    • Naray-Fejes-Toth, A.1    Canessa, C.2    Cleaveland, E.S.3    Aldrich, G.4    Fejes-Toth, G.5
  • 39
    • 10644223454 scopus 로고    scopus 로고
    • The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport
    • Naray-Fejes-Toth A., Snyder P.M., Fejes-Toth G. The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport. Proc. Natl Acad. Sci. USA 2004, 101:17434-17439.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 17434-17439
    • Naray-Fejes-Toth, A.1    Snyder, P.M.2    Fejes-Toth, G.3
  • 40
    • 0012927828 scopus 로고    scopus 로고
    • PDZ domain proteins: plug and play! Sci STKE2003: RE7.
    • Nourry C, Grant SG, Borg JP (2003) PDZ domain proteins: plug and play! Sci STKE2003: RE7.
    • (2003)
    • Nourry, C.1    Grant, S.G.2    Borg, J.P.3
  • 42
    • 34447648371 scopus 로고    scopus 로고
    • NH2 terminus of serum and glucocorticoid-regulated kinase 1 binds to phosphoinositides and is essential for isoform-specific physiological functions
    • Pao A.C., McCormick J.A., Li H., Siu J., Govaerts C., Bhalla V., Soundararajan R., Pearce D. NH2 terminus of serum and glucocorticoid-regulated kinase 1 binds to phosphoinositides and is essential for isoform-specific physiological functions. Am. J. Physiol. 2007, 292:F1741-1750.
    • (2007) Am. J. Physiol. , vol.292
    • Pao, A.C.1    McCormick, J.A.2    Li, H.3    Siu, J.4    Govaerts, C.5    Bhalla, V.6    Soundararajan, R.7    Pearce, D.8
  • 43
    • 0033151832 scopus 로고    scopus 로고
    • Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
    • Park J., Leong M.L., Buse P., Maiyar A.C., Firestone G.L., Hemmings B.A. Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. Embo 1999, J18:3024-3033.
    • (1999) Embo , vol.J18 , pp. 3024-3033
    • Park, J.1    Leong, M.L.2    Buse, P.3    Maiyar, A.C.4    Firestone, G.L.5    Hemmings, B.A.6
  • 44
    • 33847402692 scopus 로고    scopus 로고
    • Salt, sodium channels, and SGK1
    • Pearce D., Kleyman T.R. Salt, sodium channels, and SGK1. J. Clin. Invest. 2007, 117:592-595.
    • (2007) J. Clin. Invest. , vol.117 , pp. 592-595
    • Pearce, D.1    Kleyman, T.R.2
  • 45
    • 0041421190 scopus 로고    scopus 로고
    • A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactions
    • Raghuram V., Hormuth H., Foskett J.K. A kinase-regulated mechanism controls CFTR channel gating by disrupting bivalent PDZ domain interactions. Proc. Natl Acad. Sci. USA 2003, 100:9620-9625.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 9620-9625
    • Raghuram, V.1    Hormuth, H.2    Foskett, J.K.3
  • 46
    • 0033399323 scopus 로고    scopus 로고
    • Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes
    • Riccardi C., Cifone M.G., Migliorati G. Glucocorticoid hormone-induced modulation of gene expression and regulation of T-cell death: role of GITR and GILZ, two dexamethasone-induced genes. Cell Death Differ. 1999, 6:1182-1189.
    • (1999) Cell Death Differ. , vol.6 , pp. 1182-1189
    • Riccardi, C.1    Cifone, M.G.2    Migliorati, G.3
  • 48
    • 34247236088 scopus 로고    scopus 로고
    • An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis
    • Ring A.M., Leng Q., Rinehart J., Wilson F.H., Kahle K.T., Hebert S.C., Lifton R.P. An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proc. Natl Acad. Sci. USA 2007, 104:4025-4029.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 4025-4029
    • Ring, A.M.1    Leng, Q.2    Rinehart, J.3    Wilson, F.H.4    Kahle, K.T.5    Hebert, S.C.6    Lifton, R.P.7
  • 50
    • 0029948974 scopus 로고    scopus 로고
    • Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome
    • Schild L., Lu Y., Gautschi I., Schneeberger E., Lifton R.P., Rossier B.C. Identification of a PY motif in the epithelial Na channel subunits as a target sequence for mutations causing channel activation found in Liddle syndrome. Embo 1996, J15:2381-2387.
    • (1996) Embo , vol.J15 , pp. 2381-2387
    • Schild, L.1    Lu, Y.2    Gautschi, I.3    Schneeberger, E.4    Lifton, R.P.5    Rossier, B.C.6
  • 51
    • 0037134459 scopus 로고    scopus 로고
    • Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation
    • Shi H., Asher C., Chigaev A., Yung Y., Reuveny E., Seger R., Garty H. Interactions of beta and gamma ENaC with Nedd4 can be facilitated by an ERK-mediated phosphorylation. J. Biol. Chem. 2002, 277:13539-13547.
    • (2002) J. Biol. Chem. , vol.277 , pp. 13539-13547
    • Shi, H.1    Asher, C.2    Chigaev, A.3    Yung, Y.4    Reuveny, E.5    Seger, R.6    Garty, H.7
  • 52
    • 0033994483 scopus 로고    scopus 로고
    • Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel
    • Shigaev A., Asher C., Latter H., Garty H., Reuveny E. Regulation of sgk by aldosterone and its effects on the epithelial Na(+) channel. Am. J. Physiol. 2000, 278:F613-619.
    • (2000) Am. J. Physiol. , vol.278
    • Shigaev, A.1    Asher, C.2    Latter, H.3    Garty, H.4    Reuveny, E.5
  • 53
    • 0037016772 scopus 로고    scopus 로고
    • Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel
    • Snyder P.M., Olson D.R., Thomas B.C. Serum and glucocorticoid-regulated kinase modulates Nedd4-2-mediated inhibition of the epithelial Na+ channel. J. Biol. Chem. 2002, 277:5-8.
    • (2002) J. Biol. Chem. , vol.277 , pp. 5-8
    • Snyder, P.M.1    Olson, D.R.2    Thomas, B.C.3
  • 54
    • 66049127140 scopus 로고    scopus 로고
    • Epithelial sodium channel regulated by differential composition of a signaling complex
    • Soundararajan R., Melters D., Shih I.C., Wang J., Pearce D. Epithelial sodium channel regulated by differential composition of a signaling complex. Proc. Natl Acad. Sci. USA 2009, 106:7804-7809.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 7804-7809
    • Soundararajan, R.1    Melters, D.2    Shih, I.C.3    Wang, J.4    Pearce, D.5
  • 55
    • 77957258311 scopus 로고    scopus 로고
    • Role of epithelial sodium channels and their regulators in hypertension
    • Soundararajan R., Pearce D., Hughey R.P., Kleyman T.R. Role of epithelial sodium channels and their regulators in hypertension. J. Biol. Chem. 2010, 285:30363-30369.
    • (2010) J. Biol. Chem. , vol.285 , pp. 30363-30369
    • Soundararajan, R.1    Pearce, D.2    Hughey, R.P.3    Kleyman, T.R.4
  • 56
    • 37549040597 scopus 로고    scopus 로고
    • Differential Activities of Glucocorticoid-induced Leucine Zipper Protein Isoforms
    • Soundararajan R., Wang J., Melters D., Pearce D. Differential Activities of Glucocorticoid-induced Leucine Zipper Protein Isoforms. J. Biol. Chem. 2007, 282:36303-36313.
    • (2007) J. Biol. Chem. , vol.282 , pp. 36303-36313
    • Soundararajan, R.1    Wang, J.2    Melters, D.3    Pearce, D.4
  • 57
    • 78650059349 scopus 로고    scopus 로고
    • Glucocorticoid-induced Leucine Zipper 1 Stimulates the Epithelial Sodium Channel by Regulating Serum- and Glucocorticoid-induced Kinase 1 Stability and Subcellular Localization
    • Soundararajan R., Wang J., Melters D., Pearce D. Glucocorticoid-induced Leucine Zipper 1 Stimulates the Epithelial Sodium Channel by Regulating Serum- and Glucocorticoid-induced Kinase 1 Stability and Subcellular Localization. J. Biol. Chem. 2010, 285:39905-39913.
    • (2010) J. Biol. Chem. , vol.285 , pp. 39905-39913
    • Soundararajan, R.1    Wang, J.2    Melters, D.3    Pearce, D.4
  • 58
    • 28844506609 scopus 로고    scopus 로고
    • A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport
    • Soundararajan R., Zhang T.T., Wang J., Vandewalle A., Pearce D. A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport. J. Biol. Chem. 2005, 280:39970-39981.
    • (2005) J. Biol. Chem. , vol.280 , pp. 39970-39981
    • Soundararajan, R.1    Zhang, T.T.2    Wang, J.3    Vandewalle, A.4    Pearce, D.5
  • 59
    • 0029874436 scopus 로고    scopus 로고
    • WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome
    • Staub O., Dho S., Henry P., Correa J., Ishikawa T., McGlade J., Rotin D. WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome. Embo 1996, J15:2371-2380.
    • (1996) Embo , vol.J15 , pp. 2371-2380
    • Staub, O.1    Dho, S.2    Henry, P.3    Correa, J.4    Ishikawa, T.5    McGlade, J.6    Rotin, D.7
  • 60
  • 61
    • 0032582663 scopus 로고    scopus 로고
    • CNK, a RAF-binding multidomain protein required for RAS signaling
    • Therrien M., Wong A.M., Rubin G.M. CNK, a RAF-binding multidomain protein required for RAS signaling. Cell 1998, 95:343-353.
    • (1998) Cell , vol.95 , pp. 343-353
    • Therrien, M.1    Wong, A.M.2    Rubin, G.M.3
  • 62
    • 4344592072 scopus 로고    scopus 로고
    • New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis
    • Thomas C.P., Itani O.A. New insights into epithelial sodium channel function in the kidney: site of action, regulation by ubiquitin ligases, serum- and glucocorticoid-inducible kinase and proteolysis. Curr. Opin. Nephrol. Hypertens. 2004, 13:541-548.
    • (2004) Curr. Opin. Nephrol. Hypertens. , vol.13 , pp. 541-548
    • Thomas, C.P.1    Itani, O.A.2
  • 63
    • 12144279572 scopus 로고    scopus 로고
    • New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure
    • Vallon V., Lang F. New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure. Curr. Opin. Nephrol. Hypertens. 2005, 14:59-66.
    • (2005) Curr. Opin. Nephrol. Hypertens. , vol.14 , pp. 59-66
    • Vallon, V.1    Lang, F.2
  • 64
    • 69449100055 scopus 로고    scopus 로고
    • Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1
    • Vallon V., Schroth J., Lang F., Kuhl D., Uchida S. Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1. Am. J. Physiol. 2009, 297:F704-F712.
    • (2009) Am. J. Physiol. , vol.297
    • Vallon, V.1    Schroth, J.2    Lang, F.3    Kuhl, D.4    Uchida, S.5
  • 67
    • 0027195407 scopus 로고
    • Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase
    • Webster M.K., Goya L., Firestone G.L. Immediate-early transcriptional regulation and rapid mRNA turnover of a putative serine/threonine protein kinase. J. Biol. Chem. 1993, 268:11482-11485.
    • (1993) J. Biol. Chem. , vol.268 , pp. 11482-11485
    • Webster, M.K.1    Goya, L.2    Firestone, G.L.3
  • 68
    • 0027534990 scopus 로고
    • Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum
    • Webster M.K., Goya L., Ge Y., Maiyar A.C., Firestone G.L. Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum. Mol. Cell Biol. 1993, 13:2031-2040.
    • (1993) Mol. Cell Biol. , vol.13 , pp. 2031-2040
    • Webster, M.K.1    Goya, L.2    Ge, Y.3    Maiyar, A.C.4    Firestone, G.L.5
  • 70
    • 0037040897 scopus 로고    scopus 로고
    • Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2
    • Yun C.C., Chen Y., Lang F. Glucocorticoid activation of Na(+)/H(+) exchanger isoform 3 revisited. The roles of SGK1 and NHERF2. J. Biol. Chem. 2002, 277:7676-7683.
    • (2002) J. Biol. Chem. , vol.277 , pp. 7676-7683
    • Yun, C.C.1    Chen, Y.2    Lang, F.3
  • 71
    • 33847412788 scopus 로고    scopus 로고
    • Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha
    • Zhang W., Xia X., Reisenauer M.R., Rieg T., Lang F., Kuhl D., Vallon V., Kone B.C. Aldosterone-induced Sgk1 relieves Dot1a-Af9-mediated transcriptional repression of epithelial Na+ channel alpha. J. Clin. Invest. 2007, 117:773-783.
    • (2007) J. Clin. Invest. , vol.117 , pp. 773-783
    • Zhang, W.1    Xia, X.2    Reisenauer, M.R.3    Rieg, T.4    Lang, F.5    Kuhl, D.6    Vallon, V.7    Kone, B.C.8
  • 72
    • 70350540870 scopus 로고    scopus 로고
    • Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel
    • Ziera T., Irlbacher H., Fromm A., Latouche C., Krug S.M., Fromm M., Jaisser F., Borden S.A. Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel. Faseb 2009, J23:3936-3946.
    • (2009) Faseb , vol.J23 , pp. 3936-3946
    • Ziera, T.1    Irlbacher, H.2    Fromm, A.3    Latouche, C.4    Krug, S.M.5    Fromm, M.6    Jaisser, F.7    Borden, S.A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.