A mutation causing pseudohypoaldosteronism type 1 identifies a conserved glycine that is involved in the gating of the epithelial sodium channel

EMBO Journal

Volumn 16, Issue 5, 1997, Pages 899-907

  Gründer, Stefan ^a   Firsov, Dmitri ^a   Chang, Sue S ^b   Jaeger, Nicole Fowler ^a   Gautschi, Ivan ^a   Schild, Laurent ^a   Lifton, Richard P ^b   Rossier, Bernard C ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Amiloride; Channel gating; Epithelial sodium channel; Pseudohypoaldosteronism; Salt wasting syndrome

Indexed keywords

AMILORIDE; CELL SURFACE PROTEIN; GLYCINE; PROTEIN SUBUNIT; SODIUM CHANNEL;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL SURFACE; CHANNEL GATING; CONTROLLED STUDY; EPITHELIUM CELL; GENE MUTATION; ION CONDUCTANCE; MISSENSE MUTATION; MULTIGENE FAMILY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSEUDOHYPOALDOSTERONISM; SALT LOSING NEPHRITIS; SITE DIRECTED MUTAGENESIS; SODIUM CURRENT; XENOPUS LAEVIS;

AMILORIDE; AMINO ACID SEQUENCE; ANIMALS; CONSERVED SEQUENCE; EPITHELIAL SODIUM CHANNEL; GLYCINE; HUMANS; ION CHANNEL GATING; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN KINASE C; PSEUDOHYPOALDOSTERONISM; SEQUENCE HOMOLOGY, AMINO ACID; SODIUM; SODIUM CHANNELS; XENOPUS LAEVIS;

ANIMALIA; XENOPUS LAEVIS;

EID: 0344743590     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.5.899     Document Type: Article

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