Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

EMBO Journal

Volumn 16, Issue 21, 1997, Pages 6325-6336

  Staub, O ^c   Gautschi, I ^a   Ishikawa, T ^c   Breitschopf, K ^b   Ciechanover, A ^b   Schild, L ^a   Rotin, D ^c  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c NONE

Author keywords

ENaC; Half life; Lysosome; Proteasome; Ubiquitination

Indexed keywords

ARGININE; BREFELDIN A; LYSINE; PROTEASOME; PROTEIN SUBUNIT; PROTEINASE INHIBITOR; SODIUM CHANNEL; UBIQUITIN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; ENDOSOME; EPITHELIUM CELL; GENE MUTATION; HALF LIFE TIME; HUMAN; HUMAN CELL; LYSOSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN MODIFICATION; PROTEIN STABILITY; REGULATORY MECHANISM;

ACETYLCYSTEINE; AMINO ACID SEQUENCE; ANIMALS; BREFELDIN A; CALCIUM-BINDING PROTEINS; CELL LINE; CHLOROQUINE; CYCLOPENTANES; CYSTEINE ENDOPEPTIDASES; DOGS; ENDOSOMES; EPITHELIAL SODIUM CHANNEL; EPITHELIUM; HALF-LIFE; ION CHANNEL GATING; ION TRANSPORT; LIGASES; LYSOSOMES; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTAGENESIS, SITE-DIRECTED; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OOCYTES; POINT MUTATION; PROTEASE INHIBITORS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECOMBINANT FUSION PROTEINS; SODIUM; SODIUM CHANNELS; TRANSFECTION; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS; UP-REGULATION; XENOPUS LAEVIS;

ANIMALIA;

EID: 0030731428     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.21.6325     Document Type: Article

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