The Endosomal protein-sorting receptor sortilin has a role in trafficking α-1 antitrypsin

Genetics

Volumn 192, Issue 3, 2012, Pages 889-903

  Gelling, Cristy L ^a   Dawes, Ian W ^b   Perlmutter, David H ^c   Fisher, Edward A ^d   Brodsky, Jeffrey L ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; MUTANT PROTEIN; SORTILIN;

ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; CARDIOVASCULAR DISEASE; CELL VACUOLE; DISEASE SEVERITY; ENDOSOME; GENE EXPRESSION SYSTEM; GENE IDENTIFICATION; GENE LIBRARY; GENETIC ASSOCIATION; GENETIC CONSERVATION; GENETIC RISK; GOLGI COMPLEX; LIVER DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; PROTEIN TRANSPORT; RISK ASSESSMENT; SEQUENCE HOMOLOGY;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ALPHA 1-ANTITRYPSIN; ANIMALS; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; ENDOSOMES; EXTRACELLULAR SPACE; GENE EXPRESSION; GOLGI APPARATUS; HUMANS; INTRACELLULAR SPACE; MUTATION; PROTEIN TRANSPORT; RATS; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; VACUOLES; VESICULAR TRANSPORT PROTEINS;

MAMMALIA;

EID: 84869022453     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.143487     Document Type: Article

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