FK506 binding protein 8 peptidylprolyl isomerase activity manages a late stage of cystic fibrosis transmembrane conductance regulator (CFTR) folding and stability

Journal of Biological Chemistry

Volumn 287, Issue 26, 2012, Pages 21914-21925

  Hutt, Darren M ^a   Roth, Daniela Martino ^a   Chalfant, Monica A ^a   Youker, Robert T ^b,c   Matteson, Jeanne ^a   Brodsky, Jeffrey L ^b   Balch, William E ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE CHANNELS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; ENDOPLASMIC RETICULUM; EXPRESSION LEVELS; FK506-BINDING PROTEINS; FOLDING INTERMEDIATES; INTERCONVERSIONS; LATE STAGE; PEPTIDYL-PROLYL ISOMERASE; PROLYL BONDS; WILD TYPES;

BIOSYNTHESIS; CELL MEMBRANES; CHLORINE COMPOUNDS; DEGRADATION; PROTEIN FOLDING;

PROTEINS;

FK 506 BINDING PROTEIN; FK 506 BINDING PROTEIN 8; HEAT SHOCK PROTEIN 90; ISOMERASE INHIBITOR; PEPTIDYLPROLYL ISOMERASE; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CHEMICAL BOND; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FOLDING; PROTEIN STABILITY; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; WILD TYPE;

CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; DNA; ENDOPLASMIC RETICULUM; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOPHILINS; IODIDES; PROTEIN DENATURATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY; TACROLIMUS BINDING PROTEINS; TEMPERATURE; TIME FACTORS;

EID: 84862641651     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.339788     Document Type: Article

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