Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner

Cancer Letters

Volumn 336, Issue 2, 2013, Pages 347-358

  Dixit, Deobrat ^a   Ghildiyal, Ruchi ^a   Anto, Nikhil Ponnor ^a   Ghosh, Sourav ^a   Sharma, Vivek ^b   Sen, Ellora ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Glioblastoma; Guggulsterone; NF B; Ras; Shh

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 9; GUGGULSTERONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN; SANT 1; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME ACTIVATION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SENSITIZATION;

APOPTOSIS; CASPASES; CELL LINE, TUMOR; DRUG SYNERGISM; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HEDGEHOG PROTEINS; HUMANS; NF-KAPPA B; PIPERAZINES; PREGNENEDIONES; PYRAZOLES; RAS PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION;

ERINACEIDAE;

EID: 84879780888     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2013.03.025     Document Type: Article

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