Icaritin causes sustained ERK1/2 activation and induces apoptosis in human endometrial cancer cells

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Tong, Jing Shan ^a,b   Zhang, Qing Hua ^a   Huang, Xin ^a   Fu, Xue Qi ^b   Qi, Shu Tao ^a   Wang, Ya Peng ^a   Hou, Yi ^a   Sheng, Jun ^b,c   Sun, Qing Yuan ^a  

^a INSTITUTE OF ZOOLOGY   (China)

^b JILIN UNIVERSITY   (China)

^c YUNNAN AGRICULTURAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; ANTINEOPLASTIC AGENT; CASPASE; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; CYTOCHROME C; ICARITIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P21; PROTEIN P27; UNCLASSIFIED DRUG; FLAVONOID; MITOGEN ACTIVATED PROTEIN KINASE 3;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE REGULATION; CELL PROLIFERATION; CHEMICAL STRUCTURE; ENDOMETRIUM CANCER; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; HUMAN; INTRACELLULAR SIGNALING; PROTEIN EXPRESSION; PROTEIN SECRETION; BIOSYNTHESIS; CELL CYCLE; CHEMISTRY; DRUG EFFECT; ENDOMETRIUM TUMOR; ENZYMOLOGY; FEMALE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

EPIMEDIUM;

APOPTOSIS; CASPASES; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOMETRIAL NEOPLASMS; ENZYME ACTIVATION; ENZYME INDUCTION; FEMALE; FLAVONOIDS; HUMANS; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 79952371679     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016781     Document Type: Article

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