Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 19, 1998, Pages 11107-11112

  Sengupta, Tapas K ^a   Talbot, Erika S ^a   Scherle, Peggy A ^b   Ivashkiv, Lionel B ^a  

^a Weill Cornell Graduate School of Biomedical Sciences   (United States)

^b DUPONT COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; SERINE; STAT3 PROTEIN;

ANIMAL CELL; CELL STRAIN HEPG2; CHO CELL; CONFERENCE PAPER; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVATION; GENE ACTIVATION; GENE MUTATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; REPORTER GENE; SIGNAL TRANSDUCTION;

EID: 0032530159     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.19.11107     Document Type: Article

References (55)

1. O'Shea, J. J. (1997) Immunity 7, 1-11.
2. Darnell, J. E., Jr. (1997) Science 277, 1630-1635.
3. Azam, M., Lee, C., Strehlow, I. & Schindler, C. (1997) Immunity 6, 691-701.
4. Kim, T. K. & Maniatis, T. (1996) Science 273, 1717-1719.
5. Haspel, R. L., Salditt-Georgieff, M. & Darnell, J. E., Jr. (1996) EMBO J. 15, 6262-6268.
6. Shuai, K., Liao, J. & Song, M. M. (1996) Mol. Cell. Biol. 16, 4932-4941.
7. Aragane, Y., Kulms, D., Luger, T. A. & Schwarz, T. (1997) Proc. Natl. Acad. Sci. USA 94, 11490-11495.
8. Chung, C. D., Liao, J., Liu, B., Rao, X., Jay, P., Berta, P. & Shuai, K. (1997) Science 278, 1803-1805.
9. Endo, T. A., Masuhara, M., Yokouchi, M., Suzuki, R., Sakamoto, H., Mitsui, K., Matsumoto, A., Tanimura, S., Ohtsubo, M., Misawa, H., et al. (1997) Nature (London) 387, 921-924.
10. Naka, T., Narazaki, M., Hirata, M., Matsumoto, T., Minamoto, S., Aono, A., Nishimoto, N., Kajita, T., Taga, T., Yoshizaki, K., et al. (1997) Nature (London) 387, 924-929.
11. Starr, R., Willson, T. A., Viney, E. M., Murray, L. J., Rayner, J. R., Jenkins, B. J., Gonda, T. J., Alexander, W. S., Metcalf, D., Nicola, N. A., et al. (1997) Nature (London) 387, 917-921.
12. Feldman, G. M., Chuang, E. J. & Finbloom, D. S. (1995) J. Immunol. 154, 318-325.
13. Marth, T. & Kelsall, B. L. (1997) J. Exp. Med. 185, 1987-1995.
14. Bhat, G. J., Abraham, S. T. & Baker, K. M. (1996) J. Biol. Chem. 271, 22447-22452.
15. Bright, J. J., Kerr, L. D. & Sriram, S. (1997) J. Immunol. 159, 175-183.
16. Pazdrak, K., Justement, L. & Alam, R. (1995) J. Immunol. 155, 4454-4458.
17. Sengupta, T. K., Schmitt, E. M. & Ivashkiv, L. B. (1996) Proc. Natl. Acad. Sci. USA 93, 9499-9504.
18. David, M., Petricoin III, E. & Larner, A. C. (1996) J. Biol. Chem. 271, 4585-4588.
19. Petricoin III, E., David, M., Igarashi, K., Benjamin, C., Ling, L., Goelz, S., Finbloom, D. S. & Larner, A. C. (1996) Mol. Cell. Biol. 16, 1419-1424.
20. Boulton, T. G., Nye, S. H., Robbins, D. J., Ip, N. Y., Radziejewska, E., Morgenbesser, S. D., DePinho, R. A., Panayotatos, N., Cobb, M. H. & Yancopoulos, G. D. (1991) Cell 65, 663-675.
21. Woodgett, J. R., Kyriakis, J. M., Avruch, J., Zon, L. I., Zanke, B. & Templeton, D. J. (1996) Philos. Trans. R. Soc. London B 351, 135-141.
22. Marshall, C. J. (1995) Cell 80, 179-185.
23. David, M., Petricoin, E., 3rd, Benjamin, C., Pine, R., Weber, M. J. & Larner, A. C. (1995) Science 269, 1721-1723.
24. Boccaccio, C., Ando, M., Tamagnone, L., Bardelli, A., Michieli, P., Battistini, C. & Comoglio, P. M. (1998) Nature (London) 391, 285-288.
25. Bonni, A., Sun, Y., Nadal-Vicens, M., Bhatt, A., Frank, D. A., Rozovsky, I., Stahl, N., Yancopoulos, G. D. & Greenberg, M. E. (1997) Science 278, 477-483.
26. Czerniecki, B. J., Carter, C., Rivoltini, L., Koski, G. K., Kim, H. I., Weng, D. E., Roros, J. G., Hijazi, Y. M., Xu, S., Rosenberg, S. A. & Cohen, P. A. (1997) J. Immunol. 159, 3823-3837.
27. Fukada, T., Hibi, M., Yamanaka, Y., Takahashi-Tezuka, M., Fujitani, Y., Yamaguchi, T., Nakajima, K. & Hirano, T. (1996) Immunity 5, 449-460.
28. Ihara, S., Nakajima, K., Fukada, T., Hibi, M., Nagata, S., Hirano, T. & Fukui, Y. (1997) EMBO J. 16, 5345-5352.
29. Yamanaka, Y., Nakajima, K., Fukada, T., Hibi, M. & Hirano, T. (1996) EMBO J. 15, 1557-1565.
30. Minami, M., Inoue, M., Wei, S., Takeda, K., Matsumoto, M., Kishimoto, T. & Akira, S. (1996) Proc. Natl. Acad. Sci. USA 93, 3963-3966.
31. Chung, J., Uchida, E., Grammer, T. C. & Blenis, J. (1997) Mol. Cell. Biol. 17, 6508-6516.
32. Beadling, C., Ng, J., Babbage, J. W. & Cantrell, D. A. (1996) EMBO J. 15, 1902-1913.
33. Boulton, T. G., Zhong, Z., Wen, Z., Darnell, J. E., Jr., Stahl, N. & Yancopoulos, G. D. (1995) Proc. Natl. Acad. Sci. USA 92, 6915-6919.
34. Eilers, A., Georgellis, D., Klose, B., Schindler, C., Ziemiecki, A., Harpur, A. G., Wilks, A. F. & Decker, T. (1995) Mol. Cell. Biol. 15, 3579-3586.
35. Ceresa, B. P., Horvath, C. M. & Pessin, J. E. (1997) Endocrinology 138, 4131-4137.
36. Ng, J. & Cantrell, D. (1997) J. Biol. Chem. 272, 24542-24549.
37. Zhu, X., Wen, Z., Xu, L. Z. & Darnell, J. E., Jr. (1997) Mol. Cell. Biol. 17, 6618-6623.
38. Zhang, X., Blenis, J., Li, H. C., Schindler, C. & Chen-Kiang, S. (1995) Science 267, 1990-1994.
39. Wen, Z., Zhong, Z. & Darnell, J. E., Jr. (1995) Cell 82, 241-250.
40. Ihle, J. N. (1996) BioEssays 18, 95-98.
41. Welham, M. J., Duronio, V., Sanghera, J. S., Pelech, S. L. & Schrader, J. W. (1992) J. Immunol. 149, 1683-1693.
42. Ziegler-Heitbrock, H. W., Thiel, E., Futterer, A., Herzog, V., Wirtz, A. & Riethmuller, G. (1988) Int. J. Cancer 41, 456-461.
43. Sengupta, T. K., Chen, A., Zhong, Z., Darnell, J. E., Jr., & Ivashkiv, L. B. (1995) J. Exp. Med. 181, 1015-1025.
44. Zhong, Z., Wen, Z. & Darnell, J. E., Jr. (1994) Science 264, 95-98.
45. Mainiero, F., Murgia, C., Wary, K. K., Curatola, A. M., Pepe, A., Blumemberg, M., Westwick, J. K., Der, C. J. & Giancotti, F. G. (1997) EMBO J. 16, 2365-2375.
46. Zanke, B. W., Rubie, E. A., Winnett, E., Chan, J., Randall, S., Parsons, M., Boudreau, K., McInnis, M., Yan, M., Templeton, D. J., et al. (1996) J. Biol. Chem. 271, 29876-29881.
47. Alessi, D. R., Cuenda, A., Cohen, P., Dudley, D. T. & Saltiel, A. R. (1995) J. Biol. Chem. 270, 27489-27494.
48. Dudley, D. T., Pang, L., Decker, S. J., Bridges, A. J. & Saltiel, A. R. (1995) Proc. Natl. Acad. Sci. USA 92, 7686-7689.
49. Taga, T. & Kishimoto, T. (1997) Annu. Rev. Immunol. 15, 797-819.
50. Stahl, N., Farruggella, T. J., Boulton, T. G., Zhong, Z., Darnell, J. E., Jr., & Yancopoulos, G. D. (1995) Science 267, 1349-1353.
51. Kishimoto, T., Taga, T. & Akira, S. (1994) Cell 76, 253-262.
52. Ogata, A., Chauhan, D., Teoh, G., Treon, S. P., Urashima, M., Schlossman, R. L. & Anderson, K. C. (1997) J. Immunol. 159, 2212-2221.
53. Symes, A., Stahl, N., Reeves, S. A., Farruggella, T., Servidei, T., Gearan, T., Yancopoulos, G. & Fink, J. S. (1997) Curr. Biol. 7, 697-700.
54. Kim, H., Hawley, T. S., Hawley, R. G. & Baumann, H. (1998) Mol. Cell. Biol. 18, 1525-1533.
55. Ivashkiv, L. B. (1996) Adv. Immunol. 63, 337-376.