Inhibition of constitutively active Stat3 suppresses proliferation and induces apoptosis in glioblastoma multiforme cells

Oncogene

Volumn 21, Issue 55, 2002, Pages 8404-8413

  Rahaman, Shaik Ohidar ^a   Harbor, Phyllis C ^a   Chernova, Olga ^a   Barnett, Gene H ^a   Vogelbaum, Michael A ^a   Haque, S Jaharul ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Apoptosis; Glioblastoma; IL 6; Jak Stat signal transduction; Stat3

Indexed keywords

ENZYME INHIBITOR; INTERLEUKIN 6; JANUS KINASE INHIBITOR; LIPOCORTIN 5; MUTANT PROTEIN; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL 2; PROTEIN BCL X; PROTEIN MCL 1; STAT3 PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; ASTROCYTE; AUTOCRINE EFFECT; BRAIN TISSUE; CANCER CELL; CELL PROLIFERATION; CONTROLLED STUDY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; WHITE MATTER;

ACUTE-PHASE PROTEINS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BRAIN NEOPLASMS; CELL DIVISION; CELL SURVIVAL; DNA-BINDING PROTEINS; ENZYME INHIBITORS; GLIOBLASTOMA; HUMANS; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR CELLS, CULTURED; TYRPHOSTINS;

JANUS;

EID: 0037028249     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206047     Document Type: Article

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