-
1
-
-
0000527250
-
Antiarthritic and anti-inflammatory activity of gum guggul (Balsamodendron mukul Hook)
-
Gujral,M.L. et al. (1960) Antiarthritic and anti-inflammatory activity of gum guggul (Balsamodendron mukul Hook). Indian J. Physiol. Pharmacol., 4, 267-273.
-
(1960)
Indian J. Physiol. Pharmacol
, vol.4
, pp. 267-273
-
-
Gujral, M.L.1
-
2
-
-
0017687334
-
Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant
-
Sharma,J.N. et al. (1977) Comparison of the anti-inflammatory activity of Commiphora mukul (an indigenous drug) with those of phenylbutazone and ibuprofen in experimental arthritis induced by mycobacterial adjuvant. Arzneimittelforschung, 27, 1455-1457.
-
(1977)
Arzneimittelforschung
, vol.27
, pp. 1455-1457
-
-
Sharma, J.N.1
-
3
-
-
0036718907
-
Guggulsterone: An old approach to a new problem
-
Sinal,C.J. et al. (2002) Guggulsterone: An old approach to a new problem. Trends Endocrinol. Metab., 13, 275-276.
-
(2002)
Trends Endocrinol. Metab
, vol.13
, pp. 275-276
-
-
Sinal, C.J.1
-
4
-
-
0042130513
-
GUGULIPID: A natural cholesterol-lowering agent
-
Urizar,N.L. et al. (2003) GUGULIPID: A natural cholesterol-lowering agent. Annu. Rev. Nutr., 23, 303-313.
-
(2003)
Annu. Rev. Nutr
, vol.23
, pp. 303-313
-
-
Urizar, N.L.1
-
5
-
-
0023769394
-
Thyroid stimulatory action of (Z)-guggulsterone: Mechanism of action
-
Tripathi,Y.B. et al. (1988) Thyroid stimulatory action of (Z)-guggulsterone: Mechanism of action. Planta. Med., 4, 271-277.
-
(1988)
Planta. Med
, vol.4
, pp. 271-277
-
-
Tripathi, Y.B.1
-
6
-
-
0038292991
-
The effectiveness of Commiphora mukul for osteoarthritis of the knee: An outcomes study
-
Singh,B.B. et al. (2003) The effectiveness of Commiphora mukul for osteoarthritis of the knee: An outcomes study. Altern. Ther. Health Med., 9, 74-79.
-
(2003)
Altern. Ther. Health Med
, vol.9
, pp. 74-79
-
-
Singh, B.B.1
-
7
-
-
34547614631
-
Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase
-
Singh,S.V. et al. (2007) Guggulsterone-induced apoptosis in human prostate cancer cells is caused by reactive oxygen intermediate dependent activation of c-Jun NH2-terminal kinase. Cancer Res., 67, 7439-7449.
-
(2007)
Cancer Res
, vol.67
, pp. 7439-7449
-
-
Singh, S.V.1
-
8
-
-
34249058341
-
Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products
-
Shishodia,S. et al. (2007) Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products. Biochem. Pharmacol. 74, 118-130.
-
(2007)
Biochem. Pharmacol
, vol.74
, pp. 118-130
-
-
Shishodia, S.1
-
9
-
-
0020038578
-
Studies on the mechanisms involved in multistage carcinogenesis in mouse skin
-
Slaga,T.J. et al. (1982) Studies on the mechanisms involved in multistage carcinogenesis in mouse skin. J. Cell. Biochem., 18 99-119.
-
(1982)
J. Cell. Biochem
, vol.18
, pp. 99-119
-
-
Slaga, T.J.1
-
10
-
-
0031426307
-
Inhibition of phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate-caused inflammatory responses in SENCAR mouse skin by black tea polyphenols
-
Katiyar,S.K. et al. (1997) Inhibition of phorbol ester tumor promoter 12-O-tetradecanoylphorbol-13-acetate-caused inflammatory responses in SENCAR mouse skin by black tea polyphenols. Carcinogenesis, 18, 1911-1916.
-
(1997)
Carcinogenesis
, vol.18
, pp. 1911-1916
-
-
Katiyar, S.K.1
-
11
-
-
0030042774
-
Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome
-
Katiyar,S.K. et al. (1996) Inhibition of tumor promotion in SENCAR mouse skin by ethanol extract of Zingiber officinale rhizome. Cancer Res., 56, 1023-1030.
-
(1996)
Cancer Res
, vol.56
, pp. 1023-1030
-
-
Katiyar, S.K.1
-
12
-
-
0029059659
-
Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols
-
Katiyar,S.K. et al. (1995) Inhibition of 12-O-tetradecanoylphorbol-13-acetate and other skin tumor-promoter-caused induction of epidermal interleukin-1 alpha mRNA and protein expression in SENCAR mice by green tea polyphenols. J. Invest. Dermatol., 105, 394-398.
-
(1995)
J. Invest. Dermatol
, vol.105
, pp. 394-398
-
-
Katiyar, S.K.1
-
13
-
-
0036081715
-
Effects of yakuchinone A and yakuchinone B on the phorbol ester-induced expression of COX-2 and iNOS and activation of NF-κB in mouse skin
-
Chun,K.S. et al. (2002) Effects of yakuchinone A and yakuchinone B on the phorbol ester-induced expression of COX-2 and iNOS and activation of NF-κB in mouse skin. J. Environ. Pathol. Toxicol. Oncol., 21, 131-139.
-
(2002)
J. Environ. Pathol. Toxicol. Oncol
, vol.21
, pp. 131-139
-
-
Chun, K.S.1
-
14
-
-
0036681308
-
Inhibitory effects of the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol ester-induced ornithine decarboxylase activity, papilloma formation, cyclooxygenase-2 expression, inducible nitric oxide synthase expression and nuclear transcription factor kappa B activation in mouse skin
-
Seo,H.J. et al. (2002) Inhibitory effects of the standardized extract (DA-9601) of Artemisia asiatica Nakai on phorbol ester-induced ornithine decarboxylase activity, papilloma formation, cyclooxygenase-2 expression, inducible nitric oxide synthase expression and nuclear transcription factor kappa B activation in mouse skin. Int. J. Cancer 100, 456-462.
-
(2002)
Int. J. Cancer
, vol.100
, pp. 456-462
-
-
Seo, H.J.1
-
15
-
-
1642540094
-
Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice
-
Afaq,F. et al. (2003) Suppression of UVB-induced phosphorylation of mitogen-activated protein kinases and nuclear factor kappa B by green tea polyphenol in SKH-1 hairless mice. Oncogene, 22, 9254-9264.
-
(2003)
Oncogene
, vol.22
, pp. 9254-9264
-
-
Afaq, F.1
-
16
-
-
0042090509
-
Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1
-
Shishodia,S. et al. (2003) Ursolic acid inhibits nuclear factor-kappaB activation induced by carcinogenic agents through suppression of IkappaBalpha kinase and p65 phosphorylation: Correlation with down-regulation of cyclooxygenase 2, matrix metalloproteinase 9, and cyclin D1. Cancer Res., 63, 4375-4383.
-
(2003)
Cancer Res
, vol.63
, pp. 4375-4383
-
-
Shishodia, S.1
-
17
-
-
11144335895
-
Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-κB pathways and inhibits skin tumorigenesis in CD-1 mice
-
Afaq,F. et al. (2005) Anthocyanin- and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-κB pathways and inhibits skin tumorigenesis in CD-1 mice. Int. J. Cancer, 113 423-433.
-
(2005)
Int. J. Cancer
, vol.113
, pp. 423-433
-
-
Afaq, F.1
-
18
-
-
3142676732
-
Lupeol modulates NF-κB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice
-
Saleem,M. et al. (2004) Lupeol modulates NF-κB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice. Oncogene, 23 5203-5214.
-
(2004)
Oncogene
, vol.23
, pp. 5203-5214
-
-
Saleem, M.1
-
19
-
-
1042278138
-
Flavopiridol inhibits NF-κB activation induced by various carcinogens and inflammatory agents through inhibition of Ikappa Balpha kinase and p65 phosphorylation: Abrogation of cyclin D1, cyclooxygenase-2 and matrix metalloprotease-9
-
Takada,Y. et al. (2004) Flavopiridol inhibits NF-κB activation induced by various carcinogens and inflammatory agents through inhibition of Ikappa Balpha kinase and p65 phosphorylation: Abrogation of cyclin D1, cyclooxygenase-2 and matrix metalloprotease-9. J. Biol. Chem., 279, 4750-4759.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 4750-4759
-
-
Takada, Y.1
-
20
-
-
0036964816
-
Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization
-
Bharti,A.C. et al. (2002) Chemopreventive agents induce suppression of nuclear factor-kappaB leading to chemosensitization. Ann. N. Y. Acad. Sci., 973, 392-395.
-
(2002)
Ann. N. Y. Acad. Sci
, vol.973
, pp. 392-395
-
-
Bharti, A.C.1
-
21
-
-
0029002899
-
A role for phosphorylation and degradation in the control of NF-kappa B activity
-
Israel,A. (1995) A role for phosphorylation and degradation in the control of NF-kappa B activity. Trends Genet., 11, 203-205.
-
(1995)
Trends Genet
, vol.11
, pp. 203-205
-
-
Israel, A.1
-
22
-
-
0037455718
-
Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate
-
Afaq,F. et al. (2003) Inhibition of ultraviolet B-mediated activation of nuclear factor kappaB in normal human epidermal keratinocytes by green tea constituent (-)-epigallocatechin-3-gallate. Oncogene, 22, 1035-1044.
-
(2003)
Oncogene
, vol.22
, pp. 1035-1044
-
-
Afaq, F.1
-
23
-
-
0022573719
-
Tannins and related compounds: XLI, isolation and characterization of novel ellagitannins, puicacorteins A, B, C and D, and punigluconin from the bark of Punicum granatum. L
-
Tanaka,T. et al. (1986) Tannins and related compounds: XLI, isolation and characterization of novel ellagitannins, puicacorteins A, B, C and D, and punigluconin from the bark of Punicum granatum. L. Chem. Pharm. Bull., 34, 656-663.
-
(1986)
Chem. Pharm. Bull
, vol.34
, pp. 656-663
-
-
Tanaka, T.1
-
24
-
-
0029874138
-
-
Baldwin,A.S.Jr (1996) The NF-kappa B and I kappa B proteins: New discoveries and insights. Annu. Rev. Immunol., 14, 649-683.
-
Baldwin,A.S.Jr (1996) The NF-kappa B and I kappa B proteins: New discoveries and insights. Annu. Rev. Immunol., 14, 649-683.
-
-
-
-
25
-
-
0030613646
-
Catalysis by a multiprotein IkappaB kinase complex
-
Maniatis,T. (1997) Catalysis by a multiprotein IkappaB kinase complex. Science, 278, 818-819.
-
(1997)
Science
, vol.278
, pp. 818-819
-
-
Maniatis, T.1
-
26
-
-
0034535518
-
Novel approaches to chemoprevention of skin cancer
-
Bickers,D.R. et al. (2000) Novel approaches to chemoprevention of skin cancer. J. Dermatol., 27, 691-695.
-
(2000)
J. Dermatol
, vol.27
, pp. 691-695
-
-
Bickers, D.R.1
-
27
-
-
1642353497
-
Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract
-
Ding,M. et al. (2004) Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract. J. Biol. Chem., 279 10670-10676.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 10670-10676
-
-
Ding, M.1
-
28
-
-
0026083513
-
Modification of multistage carcinogenesis
-
Ito,N. and Sugano,H, eds, Karger, Basel, Switzerland, pp
-
DiGiovanni,J. (1991) Modification of multistage carcinogenesis. In Ito,N. and Sugano,H. (eds.) Modification of Tumor Development in Rodents: Progress in Experimental Tumor Research. Vol. 33. Karger, Basel, Switzerland, pp. 192-229.
-
(1991)
Modification of Tumor Development in Rodents: Progress in Experimental Tumor Research
, vol.33
, pp. 192-229
-
-
DiGiovanni, J.1
-
29
-
-
0030903321
-
Protective effects of silymarin against photocarcinogenesis in a mouse skin model
-
Katiyar,S.K. et al. (1997) Protective effects of silymarin against photocarcinogenesis in a mouse skin model. J. Natl Cancer Inst., 89, 556-566.
-
(1997)
J. Natl Cancer Inst
, vol.89
, pp. 556-566
-
-
Katiyar, S.K.1
-
30
-
-
0141798673
-
Polyamine metabolism and cancer
-
Thomas,T. et al. (2003) Polyamine metabolism and cancer. J. Cell. Mol. Med., 7, 113-126.
-
(2003)
J. Cell. Mol. Med
, vol.7
, pp. 113-126
-
-
Thomas, T.1
-
31
-
-
0346593194
-
Skin cancer chemoprevention: Strategies to save our skin
-
Einspahr,J.G. et al. (2003) Skin cancer chemoprevention: strategies to save our skin. Recent Results Cancer Res., 163 151-164.
-
(2003)
Recent Results Cancer Res
, vol.163
, pp. 151-164
-
-
Einspahr, J.G.1
-
32
-
-
0034847478
-
A definitive role of ornithine decarboxylase in photocarcinogenesis
-
Ahmad,N. et al. (2001) A definitive role of ornithine decarboxylase in photocarcinogenesis. Am. J. Pathol., 159, 885-892.
-
(2001)
Am. J. Pathol
, vol.159
, pp. 885-892
-
-
Ahmad, N.1
-
33
-
-
0031574786
-
Cell transformation, invasion, and angiogenesis: A regulatory role for ornithine decarboxylase and polyamines?
-
Auvinen,M. (1997) Cell transformation, invasion, and angiogenesis: A regulatory role for ornithine decarboxylase and polyamines? J. Natl Cancer Inst., 89, 533-537.
-
(1997)
J. Natl Cancer Inst
, vol.89
, pp. 533-537
-
-
Auvinen, M.1
-
34
-
-
0032947601
-
Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans
-
Mohan,R.R. et al. (1999) Overexpression of ornithine decarboxylase in prostate cancer and prostatic fluid in humans. Clin. Cancer Res. 5, 143-147.
-
(1999)
Clin. Cancer Res
, vol.5
, pp. 143-147
-
-
Mohan, R.R.1
-
35
-
-
0018355087
-
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion
-
Verma,A.K. et al. (1979) Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion. Cancer Res., 39, 419-425.
-
(1979)
Cancer Res
, vol.39
, pp. 419-425
-
-
Verma, A.K.1
-
36
-
-
0021993434
-
Inhibition of teleocidin-caused epidermal ornithine decarboxylase induction by phospholipase A2-, cyclooxygenase- and lipoxygenase-inhibitors
-
Nakadate,T. et al. (1985) Inhibition of teleocidin-caused epidermal ornithine decarboxylase induction by phospholipase A2-, cyclooxygenase- and lipoxygenase-inhibitors. Jpn. J. Pharmacol., 37, 253-258.
-
(1985)
Jpn. J. Pharmacol
, vol.37
, pp. 253-258
-
-
Nakadate, T.1
-
37
-
-
0027443278
-
Inhibition of oxidative stress in HeLa cells by chemopreventive agents
-
Bhimani,R.S. et al. (1993) Inhibition of oxidative stress in HeLa cells by chemopreventive agents. Cancer Res., 53, 4528-4533.
-
(1993)
Cancer Res
, vol.53
, pp. 4528-4533
-
-
Bhimani, R.S.1
-
38
-
-
0028555837
-
Regulation of prostaglandin synthase-1 and prostaglandin synthase-2
-
Herschman,H.R. (1994) Regulation of prostaglandin synthase-1 and prostaglandin synthase-2. Cancer Metastasis Rev., 13, 241-256.
-
(1994)
Cancer Metastasis Rev
, vol.13
, pp. 241-256
-
-
Herschman, H.R.1
-
39
-
-
0030479496
-
Prostaglandin endoperoxide H synthases (cyclo-oxygenases)-1 and -2
-
Smith,W.L. et al. (1996) Prostaglandin endoperoxide H synthases (cyclo-oxygenases)-1 and -2. J. Biol. Chem., 271, 33157-33160.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 33157-33160
-
-
Smith, W.L.1
-
40
-
-
0002772397
-
-
Fischer,S.M. and Slaga,T.J, eds, Martinus Nijhoff Publishing, Boston, MA, pp
-
Furstenberger,G. et al. (1985) In Fischer,S.M. and Slaga,T.J. (eds.) Arachidonic Acid Metabolism and Tumor Promotion. Martinus Nijhoff Publishing, Boston, MA, pp. 49-72.
-
(1985)
Arachidonic Acid Metabolism and Tumor Promotion
, pp. 49-72
-
-
Furstenberger, G.1
-
41
-
-
19244378298
-
Chemoprevention of colon cancer by Korean food plant components
-
Kim,D.J. et al. (2003) Chemoprevention of colon cancer by Korean food plant components. Mutat. Res., 523-524, 99-107.
-
(2003)
Mutat. Res
, vol.523-524
, pp. 99-107
-
-
Kim, D.J.1
-
42
-
-
8744234076
-
Guggulsterone inhibits NF-κB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis
-
Shishodia,S. et al. (2004) Guggulsterone inhibits NF-κB and IkappaBalpha kinase activation, suppresses expression of anti-apoptotic gene products, and enhances apoptosis. J. Biol. Chem., 279, 47148-47158.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 47148-47158
-
-
Shishodia, S.1
-
43
-
-
0033610802
-
UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratino-cyte cell line
-
Chen,W. et al. (1998) UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratino-cyte cell line. J. Biol. Chem., 273, 32176-32181.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 32176-32181
-
-
Chen, W.1
-
44
-
-
0036733681
-
Regulation of angiogenesis by vascular endothelial growth factor and angiopoietin-1 in the rat aorta model: Distinct temporal patterns of intracellular signaling correlate with induction of angiogenic sprouting
-
Zhu,W.H. et al. (2002) Regulation of angiogenesis by vascular endothelial growth factor and angiopoietin-1 in the rat aorta model: distinct temporal patterns of intracellular signaling correlate with induction of angiogenic sprouting. Am. J. Pathol., 161, 823-830.
-
(2002)
Am. J. Pathol
, vol.161
, pp. 823-830
-
-
Zhu, W.H.1
-
45
-
-
0034637575
-
c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells
-
Potapova,O. et al. (2000) c-Jun N-terminal kinase is essential for growth of human T98G glioblastoma cells. J. Biol. Chem., 275 24767-24775.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 24767-24775
-
-
Potapova, O.1
-
46
-
-
0031913814
-
Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells
-
Huang,C. et al. (1998) Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells. Proc. Natl Acad. Sci. USA, 95, 156-161.
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 156-161
-
-
Huang, C.1
-
47
-
-
0033582464
-
Oxidative damage of cardiomyocytes is limited by extracellular regulated kinases 1/2-mediated induction of cyclooxygenase-2
-
Adderley,S.R. et al. (1999) Oxidative damage of cardiomyocytes is limited by extracellular regulated kinases 1/2-mediated induction of cyclooxygenase-2. J. Biol. Chem., 274, 5038-5046.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 5038-5046
-
-
Adderley, S.R.1
-
48
-
-
0032698069
-
The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression: The role of TATA-binding protein (TBP)
-
Carter,A.B. et al. (1999) The p38 mitogen-activated protein kinase is required for NF-κB-dependent gene expression: The role of TATA-binding protein (TBP). J. Biol. Chem., 274, 30858-30863.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 30858-30863
-
-
Carter, A.B.1
-
49
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity
-
Karin,M. et al. (2000) Phosphorylation meets ubiquitination: The control of NF-[kappa]B activity. Annu. Rev. Immunol., 18, 621-663.
-
(2000)
Annu. Rev. Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
-
50
-
-
85047699198
-
Nuclear transcription factor-kappaB as a target for cancer drug development
-
Garg,A. et al. (2002) Nuclear transcription factor-kappaB as a target for cancer drug development. Leukemia, 16, 1053-1068.
-
(2002)
Leukemia
, vol.16
, pp. 1053-1068
-
-
Garg, A.1
-
51
-
-
0033596126
-
Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway
-
Epinat,J.C. et al. (1999) Diverse agents act at multiple levels to inhibit the Rel/NF-κB signal transduction pathway. Oncogene, 18, 6896-6909.
-
(1999)
Oncogene
, vol.18
, pp. 6896-6909
-
-
Epinat, J.C.1
-
52
-
-
33744969804
-
Transcriptional regulation via cysteine thiol modification: A novel molecular strategy for chemoprevention and cytoprotection
-
Na,H.K. et al. (2006) Transcriptional regulation via cysteine thiol modification: A novel molecular strategy for chemoprevention and cytoprotection. Mol. Carcinog., 45, 368-380.
-
(2006)
Mol. Carcinog
, vol.45
, pp. 368-380
-
-
Na, H.K.1
|