Bicyclic triterpenoid Iripallidal induces apoptosis and inhibits Akt/mTOR pathway in glioma cells

BMC Cancer

Volumn 10, Issue , 2010, Pages

  Koul, Nitin ^a   Sharma, Vivek ^a   Dixit, Deobrat ^a   Ghosh, Sadashib ^a   Sen, Ellora ^a  

^a NATIONAL BRAIN RESEARCH CENTRE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

26 HYDROXY 22 ALPHA METHYLCYCLOIRID 16 ENAL; CASPASE 3; CYCLIN D; IRIPALLIDAL; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; S6 KINASE; STAT3 PROTEIN; TELOMERASE; TRITERPENOID; TYROSINE; UNCLASSIFIED DRUG; 26 HYDROXY 22 METHYLCYCLOIRID 16 ENAL; 26-HYDROXY-22-METHYLCYCLOIRID-16-ENAL; ACROLEIN; CYCLOHEXANOL DERIVATIVE; DRUG DERIVATIVE;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL PROLIFERATION; CELL VIABILITY; COLONY FORMATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; GLIOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; BRAIN TUMOR; DRUG ANTAGONISM; DRUG EFFECT; GLIOBLASTOMA; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

ACROLEIN; APOPTOSIS; BLOTTING, WESTERN; BRAIN NEOPLASMS; CASPASE 3; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOHEXANOLS; GLIOBLASTOMA; HUMANS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TELOMERASE; TOR SERINE-THREONINE KINASES;

EID: 78650899052     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-10-328     Document Type: Article

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