Cytotoxicity of dioscin in human gastric carcinoma cells through death receptor and mitochondrial pathways

Journal of Applied Toxicology

Volumn 33, Issue 8, 2013, Pages 712-722

  Hu, Mingming ^a   Xu, Lina ^a   Yin, Lianhong ^a   Qi, Yan ^a   Li, Hua ^a   Xu, Youwei ^a   Han, Xu ^a   Peng, Jinyong ^a   Wan, Xianyao ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Death receptor pathway; Dioscin; Mitochondrial pathway; SGC 7901 cancer cells

Indexed keywords

ACRIDINE ORANGE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CYTOCHROME C; DEATH RECEPTOR; DIOSCIN; ETHIDIUM BROMIDE; FAS LIGAND; MESSENGER RNA; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN BID; PROTEIN P53; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; CYTOTOXICITY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CARCINOMA; WESTERN BLOTTING;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2 HOMOLOGOUS ANTAGONIST-KILLER PROTEIN; BCL-2-ASSOCIATED X PROTEIN; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; DIOSGENIN; DOWN-REGULATION; FAS LIGAND PROTEIN; HUMANS; MITOCHONDRIA; RADIOIMMUNOASSAY; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84879503246     PISSN: 0260437X     EISSN: 10991263     Source Type: Journal    
DOI: 10.1002/jat.2715     Document Type: Article

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