Application of proteomic and bioinformatic techniques for studying the hepatoprotective effect of dioscin against CCl 4-induced liver damage in mice

Planta Medica

Volumn 77, Issue 5, 2011, Pages 407-415

  Lu, Binan ^a   Yin, Lianhong ^a   Xu, Lina ^a   Peng, Jinyong ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

bioinformatics; CCl 4induced liver injury; dioscin; hepatoprotective effect; proteomics

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANNEXIN; ANNEXIN 6; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CYTOGLOBIN; DIOSCIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 5; ISOVALERYL COENZYME A DEHYDROGENASE; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; LIVER PROTEIN; NUCLEOSIDE DIPHOSPHATE KINASE A; PROTEIN S6; SILYMARIN; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BIOINFORMATICS; CHINESE MEDICINE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; GEL ELECTROPHORESIS; HISTOPATHOLOGY; LACTATE DEHYDROGENASE BLOOD LEVEL; LIVER INJURY; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEOMICS;

ANIMALS; CARBON TETRACHLORIDE; COMPUTATIONAL BIOLOGY; DIOSGENIN; DRUG-INDUCED LIVER INJURY; LIVER; MALE; MICE; NECROSIS; PROTECTIVE AGENTS; PROTEIN INTERACTION MAPPING; PROTEOMICS; SILYMARIN;

MUS;

EID: 79953027878     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0030-1250461     Document Type: Article

References (34)

1. Larson A M., Polson J, Fontana R J., Davern T J., Lalani E, Hynan L S., Reisch J S., Schiødt F V., Ostapowicz G, Shakil A O., Lee W M. Acute Liver Failure Study Group. Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study. Hepatology 2005 42 1364-1372 (Pubitemid 43260039)
2. 4- induced cirrhosis with ascites in the mouse. J Hepatol 2009 51 991-999
3. Mohamed Saleem T S., Madhusudhana Chetty C, Ramkanth S, Rajan V S. T., Mahesh Kumar K, Gauthaman K. Hepatoprotective Herbs - A Review. Int J Res Pharm Sci 2010 1 1-5
4. Nakamura T, Komori C, Lee Y, Hashimoto F, Yahara S, Nohara T, Ejima A. Cytotoxic activities of Solanum steroidal glycosides. Biol Pharm Bull 1996 19 564-566 (Pubitemid 26144614)
5. Wang Z, Zhou J B., Ju Y, Zhang H, Liu M, Li X. Effect of two saponins extracted from the Polygonatum zanlanscianense Pamp on the human leukemia (HL-60) cells. Biol Pharm Bull 2001 24 159-162 (Pubitemid 32175567)
6. Sautour M, Mitaine-Offer A C., Miyamoto T, Dongmo A, Lacaille-Dubois M A. Antifungal steroid saponins from Dioscorea cayenensis. Planta Med 2004 70 90-92 (Pubitemid 38233925)
7. Takechi M, Shimada S, Tanaka Y. Structure-activity relationships of the saponins dioscin and dioscinin. Phytochemistry 1991 30 3943-3944
8. Zhao J, Jiang P, Zhang W. Molecular networks for the study of TCM pharmacology. Brief Bioinform 2010 11 417-430
9. Yue Q X., Cao Z W., Guan S H., Liu X H., Tao L, Wu W Y., Li Y X., Yang P Y., Liu X, Guo D A. Proteomics characterization of the cytotoxicity mechanism of ganoderic acid D and computer-automated estimation of the possible drug target network. Mol Cell Proteomics 2008 7 949-961 (Pubitemid 351737094)
10. Cecconi D, Donadelli M, Dalla P E., Rinalducci S, Zolla L, Scupoli M T., Righetti P G., Scarpa A, Palmieri M. Synergistic effect of trichostatin A and 5-aza-2- deoxycytidine on growth inhibition of pancreatic endocrine tumour cell lines: a proteomic study. Proteomics 2009 9 1952-1966
11. Rodríguez-Martín A, Acosta R, Liddell S, Núñez F, Benito M J., Asensio M A. Characterization of the novel antifungal chitosanase PgChP and the encoding gene from Penicillium chrysogenum. Appl Microbiol Biotechnol 2010 88 519-528
12. Boutin M, Berthelette C, Gervais F G., Scholand M B., Hoidal J, Leppert M F., Bateman K P., Thibault P. High-sensitivity nanoLC-MS/MS analysis of urinary desmosine and isodesmosine. Anal Chem 2009 81 1881-1887
13. Mohammed S, Kraiczek K, Pinkse M W., Lemeer S, Benschop J J., Heck A J. Chip-Based Enrichment and NanoLC-MS/MS Analysis of Phosphopeptides from Whole Lysates. J Proteome Res 2008 7 1565-1571
14. Lu B N., Hu M M., Liu K X., Peng J Y. Cytotoxicity of berberine on human cervical carcinoma HeLa cells through mitochondria, death receptor and MAPK path- ways, and in-silico drug-target prediction. Toxicol In Vitro 2010 24 1482-1490
15. Hsu Y W., Tsai C F., Chen W K., Lu F J. Protective effects of seabuckthorn (Hippophae rhamnoides L.) seed oil against carbon tetrachloride-induced hepatotoxicity in mice. Food Chem Toxicol 2009 47 2281-2288
16. Wang N, Li P, Wang Y, Peng W, Wu Z, Tan S, Liang S, Shen X, Su W. Hepatoprotective effect of Hypericum japonicum extract and its fractions. J Ethnopharmacol 2008 116 1-6
17. Xenarios I, Rice D W., Salwinski L, Baron M K., Marcotte E M., Eisenberg D. DIP: the database of interacting proteins. Nucl Acids Res 2000 28 289-291 (Pubitemid 30047782)
18. Zanzoni A, Montecchi-Palazzi L, Quondam M, Ausiello G, Helmer-Citterich M, Cesareni G. MINT: a Molecular INTeraction database. FEBS Lett 2002 513 135-140 (Pubitemid 34242991)
19. Klein P, Ravi R. A nearly best-possible approximation algorithm for node-weighted steiner trees. J Algorith 1995 19 104-14
20. Tavazoie S, Hughes J D., Campbell M J., Cho R J., Church G M. Systematic determination of genetic network architecture. Nat Genet 1999 22 281-285 (Pubitemid 29297256)
21. Zhao J, Ding G H., Tao L, Yu H, Yu Z H., Luo J H., Cao Z W., Li Y X. Modular co-evolution of metabolic networks. BMC Bioinform 2007 8 311
22. Yu C, Wang F, Jin C, Wu X, Chan W K., McKeehan W L. Increased carbon tetrachloride-induced liver injury and fibrosis in FGFR4-deficient mice. Am J Pathol 2002 161 2003-2010 (Pubitemid 35434846)
23. Recknagel R O., Glende Jr. E A., Dolak J A., Waller R L. Mechanisms of carbon tetrachloride toxicity. Pharmacol Ther 1989 43 139-154 (Pubitemid 19200126)
24. Jia N, Liu X, Wen J, Qian L, Qian X, Wu Y, Fan G. A proteomic method for analysis of CYP450s protein expression changes in carbon tetrachloride induced male rat liver microsomes. Toxicology 2007 237 1-11 (Pubitemid 47033948)
25. Yuan L P., Chen F H., Ling L, Dou P F., Bo H, Zhong M M., Xia L J. Protective effects of total flavonoids of Bidens pilosa L. (TFB) on animal liver injury and liver fibrosis. J Ethnopharmacol 2008 116 539-546
26. 2+. J Biol Chem 1997 272 30873-30879 (Pubitemid 27527530)
27. Little E, Ramakrishnan M, Roy B, Gazita G, Lee A S. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit Rev Eukaryot Gene Expr 1994 4 1-18 (Pubitemid 24238439)
28. Yu Z, Luo H, Fu W, Mattson M P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp Neurol 1999 155 302-314 (Pubitemid 29124724)
29. Gerke V, Moss S E. Annexins and membrane dynamics. Biochim Biophys Acta 1997 1357 129-154 (Pubitemid 27278039)
30. Donato R, Russo-Marie F. The annexins: structure and functions. Cell Calcium 1999 26 85-89
31. 2+ entry by stabilizing the cortical actin cytoskeleton. J Biol Chem 2009 284 17227-17242
32. Förster-Fromme K, Jendrossek D. Biochemical characterization of isovaleryl-CoA dehydrogenase (LiuA) of Pseudomonas aeruginosa and the importance of liu genes for a functional catabolic pathway of methyl-branched compounds. FEMS Microbiol Lett 2008 286 78-84 (Pubitemid 352040402)
33. Man K N., Philipsen S, Tan-Un K C. Localization and expression pattern of cytoglobin in carbon tetrachloride-induced liver fibrosis. Toxicol Lett 2008 183 36-44
34. Colomb M G., Chéruy A, Vignais P V. Nucleoside diphosphokinase from beef heart mitochondria. Purification and properties. Biochemistry 1969 8 1926-1939