Structural analogues of diosgenyl saponins: Synthesis and anticancer activity

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 22, 2009, Pages 7670-7679

  Kaskiw, Matthew J ^a   Tassotto, Mary Lynn ^b   Mok, Mac ^a   Tokar, Stacey L ^a   Pycko, Roxanne ^a,b,c   Th'ng, John ^a,b,c   Jiang, Zi Hua ^a  

^a LAKEHEAD UNIVERSITY   (Canada)

^b Regional Cancer Care   (Canada)

^c NORTHERN ONTARIO SCHOOL OF MEDICINE   (Canada)

Author keywords

Anticancer; Aromatic nitro functionality; Cytotoxicity; Dioscin; Diosgenin; Saponin; Synthesis

Indexed keywords

DIOSGENIN; DIOSGENIN DERIVATIVE; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL STRAIN MCF 7; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DIOSGENIN; DISACCHARIDES; FEMALE; HELA CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MONOSACCHARIDES; SAPONINS; UTERINE CERVICAL NEOPLASMS;

EID: 71749084455     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.09.046     Document Type: Article

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