-
1
-
-
0015383455
-
Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
-
Kerr J.F., Wyllie A.H., and Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26 4 (1972) 239-257
-
(1972)
Br J Cancer
, vol.26
, Issue.4
, pp. 239-257
-
-
Kerr, J.F.1
Wyllie, A.H.2
Currie, A.R.3
-
2
-
-
34247385565
-
Apoptosis pathways as promising targets for skin cancer therapy
-
Eberle J., Fecker L.F., Forschner T., Ulrich C., Rowert-Huber J., and Stockfleth E. Apoptosis pathways as promising targets for skin cancer therapy. Br J Dermatol 156 (2007) 18-24
-
(2007)
Br J Dermatol
, vol.156
, pp. 18-24
-
-
Eberle, J.1
Fecker, L.F.2
Forschner, T.3
Ulrich, C.4
Rowert-Huber, J.5
Stockfleth, E.6
-
3
-
-
33747884339
-
DNA damage-induced cell death by apoptosis
-
Roos W.P., and Kaina B. DNA damage-induced cell death by apoptosis. Trends Mol Med 12 9 (2006) 440-450
-
(2006)
Trends Mol Med
, vol.12
, Issue.9
, pp. 440-450
-
-
Roos, W.P.1
Kaina, B.2
-
4
-
-
33646087420
-
The apoptosome: physiological, developmental, and pathological modes of regulation
-
Schafer Z.T., and Kornbluth S. The apoptosome: physiological, developmental, and pathological modes of regulation. Dev Cell 10 5 (2006) 549-561
-
(2006)
Dev Cell
, vol.10
, Issue.5
, pp. 549-561
-
-
Schafer, Z.T.1
Kornbluth, S.2
-
5
-
-
0037276437
-
The CD95(APO-1/Fas) DISC and beyond
-
Peter M.E., and Krammer P.H. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ 10 1 (2003) 26-35
-
(2003)
Cell Death Differ
, vol.10
, Issue.1
, pp. 26-35
-
-
Peter, M.E.1
Krammer, P.H.2
-
6
-
-
0036217977
-
Lymphocyte-mediated cytotoxicity
-
Russell J.H., and Ley T.J. Lymphocyte-mediated cytotoxicity. Annu Rev Immunol 20 (2002) 323-370
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 323-370
-
-
Russell, J.H.1
Ley, T.J.2
-
7
-
-
27644466759
-
Autophagy and signaling: their role in cell survival and cell death
-
Codogno P., and Meijer A.J. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12 (2005) 1509-1518
-
(2005)
Cell Death Differ
, vol.12
, pp. 1509-1518
-
-
Codogno, P.1
Meijer, A.J.2
-
8
-
-
22944473652
-
New approaches and therapeutics targeting apoptosis in disease
-
Fischer U., and Schulze-Osthoff K. New approaches and therapeutics targeting apoptosis in disease. Pharmacol Rev 57 2 (2005) 187-215
-
(2005)
Pharmacol Rev
, vol.57
, Issue.2
, pp. 187-215
-
-
Fischer, U.1
Schulze-Osthoff, K.2
-
9
-
-
22144460556
-
Apoptosis-based therapies for hematologic malignancies
-
Reed J.C., and Pellecchia M. Apoptosis-based therapies for hematologic malignancies. Blood 106 2 (2005) 408-418
-
(2005)
Blood
, vol.106
, Issue.2
, pp. 408-418
-
-
Reed, J.C.1
Pellecchia, M.2
-
10
-
-
41149152733
-
How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
-
Chipuk J.E., and Green D.R. How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?. Trends Cell Biol 18 4 (2008) 157-164
-
(2008)
Trends Cell Biol
, vol.18
, Issue.4
, pp. 157-164
-
-
Chipuk, J.E.1
Green, D.R.2
-
11
-
-
37549048249
-
The BCL-2 protein family: opposing activities that mediate cell death
-
Youle R.J., and Strasser A. The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 9 1 (2008) 47-59
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, Issue.1
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
12
-
-
18344377030
-
The p53 pathway: positive and negative feedback loops
-
Harris S.L., and Levine A.J. The p53 pathway: positive and negative feedback loops. Oncogene 24 17 (2005) 2899-2908
-
(2005)
Oncogene
, vol.24
, Issue.17
, pp. 2899-2908
-
-
Harris, S.L.1
Levine, A.J.2
-
13
-
-
33748961826
-
Mitochondria as the target of the pro-apoptotic protein Bax
-
Er E., Oliver L., Cartron P.F., Juin P., Manon S., and Vallette F.M. Mitochondria as the target of the pro-apoptotic protein Bax. Biochim Biophys Acta-Bioenerg 1757 9-10 (2006) 1301-1311
-
(2006)
Biochim Biophys Acta-Bioenerg
, vol.1757
, Issue.9-10
, pp. 1301-1311
-
-
Er, E.1
Oliver, L.2
Cartron, P.F.3
Juin, P.4
Manon, S.5
Vallette, F.M.6
-
14
-
-
4344691959
-
Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology
-
Shiozaki E.N., and Shi Y.G. Caspases, IAPs and Smac/DIABLO: mechanisms from structural biology. Trends Biochem Sci 29 9 (2004) 486-494
-
(2004)
Trends Biochem Sci
, vol.29
, Issue.9
, pp. 486-494
-
-
Shiozaki, E.N.1
Shi, Y.G.2
-
15
-
-
39449115415
-
The mitochondrial serine protease HtrA2/Omi: an overview
-
Walle L.V., Lamkanfi M., and Vandenabeele P. The mitochondrial serine protease HtrA2/Omi: an overview. Cell Death Differ 15 3 (2008) 453-460
-
(2008)
Cell Death Differ
, vol.15
, Issue.3
, pp. 453-460
-
-
Walle, L.V.1
Lamkanfi, M.2
Vandenabeele, P.3
-
16
-
-
38549123294
-
Therapeutic potential of AIF-mediated caspase-independent programmed cell death
-
Lorenzo H.K., and Susin S.A. Therapeutic potential of AIF-mediated caspase-independent programmed cell death. Drug Resist Updates 10 6 (2007) 235-255
-
(2007)
Drug Resist Updates
, vol.10
, Issue.6
, pp. 235-255
-
-
Lorenzo, H.K.1
Susin, S.A.2
-
17
-
-
34347272654
-
Regulation of caspase-9 activity by differential binding to the apoptosome complex
-
Saikumar P., Mikhailova M., and Pandeswara S.L. Regulation of caspase-9 activity by differential binding to the apoptosome complex. Front Biosci 12 (2007) 3343-3354
-
(2007)
Front Biosci
, vol.12
, pp. 3343-3354
-
-
Saikumar, P.1
Mikhailova, M.2
Pandeswara, S.L.3
-
18
-
-
0347601880
-
A decade of caspases
-
Degterev A., Boyce M., and Yuan J. A decade of caspases. Oncogene 22 53 (2003) 8543-8567
-
(2003)
Oncogene
, vol.22
, Issue.53
, pp. 8543-8567
-
-
Degterev, A.1
Boyce, M.2
Yuan, J.3
-
19
-
-
0034912853
-
Caspases: more than just killers?
-
Los M., Stroh C., Janicke R.U., Engels I.H., and Schulze-Osthoff K. Caspases: more than just killers?. Trends Immunol 22 1 (2001) 31-34
-
(2001)
Trends Immunol
, vol.22
, Issue.1
, pp. 31-34
-
-
Los, M.1
Stroh, C.2
Janicke, R.U.3
Engels, I.H.4
Schulze-Osthoff, K.5
-
20
-
-
0242432345
-
Many cuts to ruin: a comprehensive update of caspase substrates
-
Fischer U., Janicke R.U., and Schulze-Osthoff K. Many cuts to ruin: a comprehensive update of caspase substrates. Cell Death Differ 10 1 (2003) 76-100
-
(2003)
Cell Death Differ
, vol.10
, Issue.1
, pp. 76-100
-
-
Fischer, U.1
Janicke, R.U.2
Schulze-Osthoff, K.3
-
22
-
-
0035720233
-
The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis
-
Raisova M., Hossini A.M., Eberle J., Riebeling C., Wieder T., Sturm I., et al. The Bax/Bcl-2 ratio determines the susceptibility of human melanoma cells to CD95/Fas-mediated apoptosis. J Invest Dermatol 117 2 (2001) 333-340
-
(2001)
J Invest Dermatol
, vol.117
, Issue.2
, pp. 333-340
-
-
Raisova, M.1
Hossini, A.M.2
Eberle, J.3
Riebeling, C.4
Wieder, T.5
Sturm, I.6
-
23
-
-
0142027948
-
Ways of dying: multiple pathways to apoptosis
-
Adams J.M. Ways of dying: multiple pathways to apoptosis. Genes Dev 17 20 (2003) 2481-2495
-
(2003)
Genes Dev
, vol.17
, Issue.20
, pp. 2481-2495
-
-
Adams, J.M.1
-
24
-
-
0036463405
-
A matter of life and death
-
Green D.R., and Evan G.I. A matter of life and death. Cancer Cell 1 1 (2002) 19-30
-
(2002)
Cancer Cell
, vol.1
, Issue.1
, pp. 19-30
-
-
Green, D.R.1
Evan, G.I.2
-
25
-
-
0035229427
-
The mitochondrion in apoptosis: how Pandora's box opens
-
Zamzami N., and Kroemer G. The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2 1 (2001) 67-71
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, Issue.1
, pp. 67-71
-
-
Zamzami, N.1
Kroemer, G.2
-
27
-
-
33750619845
-
How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?
-
Antignani A., and Youle R.J. How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?. Curr Opin Cell Biol 18 6 (2006) 685-689
-
(2006)
Curr Opin Cell Biol
, vol.18
, Issue.6
, pp. 685-689
-
-
Antignani, A.1
Youle, R.J.2
-
28
-
-
0021270716
-
Molecular-cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the T(11-14) chromosome-translocation
-
Tsujimoto Y., Yunis J., Onoratoshowe L., Erikson J., Nowell P.C., and Croce C.M. Molecular-cloning of the chromosomal breakpoint of B-cell lymphomas and leukemias with the T(11-14) chromosome-translocation. Science 224 4656 (1984) 1403-1406
-
(1984)
Science
, vol.224
, Issue.4656
, pp. 1403-1406
-
-
Tsujimoto, Y.1
Yunis, J.2
Onoratoshowe, L.3
Erikson, J.4
Nowell, P.C.5
Croce, C.M.6
-
29
-
-
0027166048
-
Bcl-2 heterodimerizes in-vivo with a conserved homolog, Bax, that accelerates programmed cell-death
-
Oltvai Z.N., Milliman C.L., and Korsmeyer S.J. Bcl-2 heterodimerizes in-vivo with a conserved homolog, Bax, that accelerates programmed cell-death. Cell 74 4 (1993) 609-619
-
(1993)
Cell
, vol.74
, Issue.4
, pp. 609-619
-
-
Oltvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
30
-
-
33847328289
-
The Bcl-2 apoptotic switch in cancer development and therapy
-
Adams J.M., and Cory S. The Bcl-2 apoptotic switch in cancer development and therapy. Oncogene 26 9 (2007) 1324-1337
-
(2007)
Oncogene
, vol.26
, Issue.9
, pp. 1324-1337
-
-
Adams, J.M.1
Cory, S.2
-
31
-
-
20344398190
-
G(1)/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression
-
Collins N.L., Reginato M.J., Paulus J.K., Sgroi D.C., LaBaer J., and Brugge J.S. G(1)/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression. Mol Cell Biol 25 12 (2005) 5282-5291
-
(2005)
Mol Cell Biol
, vol.25
, Issue.12
, pp. 5282-5291
-
-
Collins, N.L.1
Reginato, M.J.2
Paulus, J.K.3
Sgroi, D.C.4
LaBaer, J.5
Brugge, J.S.6
-
32
-
-
85047699843
-
Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53
-
Mathai J.P., Germain M., Marcellus R.C., and Shore G.C. Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53. Oncogene 21 16 (2002) 2534-2544
-
(2002)
Oncogene
, vol.21
, Issue.16
, pp. 2534-2544
-
-
Mathai, J.P.1
Germain, M.2
Marcellus, R.C.3
Shore, G.C.4
-
33
-
-
27544446991
-
Life in the balance: how BH3-only proteins induce apoptosis
-
Willis S.N., and Adams J.M. Life in the balance: how BH3-only proteins induce apoptosis. Curr Opin Cell Biol 17 6 (2005) 617-625
-
(2005)
Curr Opin Cell Biol
, vol.17
, Issue.6
, pp. 617-625
-
-
Willis, S.N.1
Adams, J.M.2
-
34
-
-
34748924281
-
Bcl-2-regulated apoptosis: mechanism and therapeutic potential
-
Adams J.M., and Cory S. Bcl-2-regulated apoptosis: mechanism and therapeutic potential. Curr Opin Immunol 19 5 (2007) 488-496
-
(2007)
Curr Opin Immunol
, vol.19
, Issue.5
, pp. 488-496
-
-
Adams, J.M.1
Cory, S.2
-
35
-
-
19944432123
-
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
-
Chen L., Willis S.N., Wei A., Smith B.J., Fletcher J.I., Hinds M.G., et al. Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17 3 (2005) 393-403
-
(2005)
Mol Cell
, vol.17
, Issue.3
, pp. 393-403
-
-
Chen, L.1
Willis, S.N.2
Wei, A.3
Smith, B.J.4
Fletcher, J.I.5
Hinds, M.G.6
-
36
-
-
13944277343
-
BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
-
Kuwana T., Bouchier-Hayes L., Chipuk J.E., Bonzon C., Sullivan B.A., Green D.R., et al. BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol Cell 17 4 (2005) 525-535
-
(2005)
Mol Cell
, vol.17
, Issue.4
, pp. 525-535
-
-
Kuwana, T.1
Bouchier-Hayes, L.2
Chipuk, J.E.3
Bonzon, C.4
Sullivan, B.A.5
Green, D.R.6
-
37
-
-
37549069901
-
BCL-2 family proteins: critical checkpoints of apoptotic cell death
-
Danial N.N. BCL-2 family proteins: critical checkpoints of apoptotic cell death. Clin Cancer Res 13 24 (2007) 7254-7263
-
(2007)
Clin Cancer Res
, vol.13
, Issue.24
, pp. 7254-7263
-
-
Danial, N.N.1
-
38
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis S.N., Fletcher J.I., Kaufmann T., van Delft M.F., Chen L., Czabotar P.E., et al. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315 5813 (2007) 856-859
-
(2007)
Science
, vol.315
, Issue.5813
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
van Delft, M.F.4
Chen, L.5
Czabotar, P.E.6
-
39
-
-
0034520466
-
Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells
-
Saeki K., Yuo A., Okuma E., Yazaki Y., Susin S.A., Kroemer G., et al. Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells. Cell Death Differ 7 12 (2000) 1263-1269
-
(2000)
Cell Death Differ
, vol.7
, Issue.12
, pp. 1263-1269
-
-
Saeki, K.1
Yuo, A.2
Okuma, E.3
Yazaki, Y.4
Susin, S.A.5
Kroemer, G.6
-
40
-
-
43149099007
-
BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes
-
Terrones O., Etxebarria A., Landajuela A., Landeta O., Antonsson B., and Basanez G. BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes. J Biol Chem 283 12 (2008) 7790-7803
-
(2008)
J Biol Chem
, vol.283
, Issue.12
, pp. 7790-7803
-
-
Terrones, O.1
Etxebarria, A.2
Landajuela, A.3
Landeta, O.4
Antonsson, B.5
Basanez, G.6
-
41
-
-
0028832667
-
A conserved domain in Bak, distinct from Bh1 and Bh2, mediates cell-death and protein-binding functions
-
Chittenden T., Flemington C., Houghton A.B., Ebb R.G., Gallo G.J., Elangovan B., et al. A conserved domain in Bak, distinct from Bh1 and Bh2, mediates cell-death and protein-binding functions. EMBO J 14 22 (1995) 5589-5596
-
(1995)
EMBO J
, vol.14
, Issue.22
, pp. 5589-5596
-
-
Chittenden, T.1
Flemington, C.2
Houghton, A.B.3
Ebb, R.G.4
Gallo, G.J.5
Elangovan, B.6
-
42
-
-
0028812606
-
Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins
-
Boyd J.M., Gallo G.J., Elangovan B., Houghton A.B., Malstrom S., Avery B.J., et al. Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. Oncogene 11 9 (1995) 1921-1928
-
(1995)
Oncogene
, vol.11
, Issue.9
, pp. 1921-1928
-
-
Boyd, J.M.1
Gallo, G.J.2
Elangovan, B.3
Houghton, A.B.4
Malstrom, S.5
Avery, B.J.6
-
43
-
-
0028809209
-
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death
-
Yang E., Zha J., Jockel J., Boise L.H., Thompson C.B., and Korsmeyer S.J. Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death. Cell 80 2 (1995) 285-291
-
(1995)
Cell
, vol.80
, Issue.2
, pp. 285-291
-
-
Yang, E.1
Zha, J.2
Jockel, J.3
Boise, L.H.4
Thompson, C.B.5
Korsmeyer, S.J.6
-
44
-
-
33750834023
-
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized
-
van Delft M.F., Wei A.H., Mason K.D., Vandenberg C.J., Chen L., Czabotar P.E., et al. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. Cancer Cell 10 5 (2006) 389-399
-
(2006)
Cancer Cell
, vol.10
, Issue.5
, pp. 389-399
-
-
van Delft, M.F.1
Wei, A.H.2
Mason, K.D.3
Vandenberg, C.J.4
Chen, L.5
Czabotar, P.E.6
-
45
-
-
38549130324
-
BH3 mimetics to improve cancer therapy; mechanisms and examples
-
Zhang L., Ming L., and Yu H. BH3 mimetics to improve cancer therapy; mechanisms and examples. Drug Resist Updates 10 6 (2007) 207-217
-
(2007)
Drug Resist Updates
, vol.10
, Issue.6
, pp. 207-217
-
-
Zhang, L.1
Ming, L.2
Yu, H.3
-
46
-
-
38549111246
-
Overcoming apoptosis deficiency of melanoma - hope for new therapeutic approaches
-
Eberle J., Kurbanov B.M., Hossini A.M., Trefter U., and Fecker L.F. Overcoming apoptosis deficiency of melanoma - hope for new therapeutic approaches. Drug Resist Updates 10 6 (2007) 218-234
-
(2007)
Drug Resist Updates
, vol.10
, Issue.6
, pp. 218-234
-
-
Eberle, J.1
Kurbanov, B.M.2
Hossini, A.M.3
Trefter, U.4
Fecker, L.F.5
-
47
-
-
0037390872
-
Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum
-
Mund T., Gewies A., Schoenfeld N., Bauer M.K., and Grimm S. Spike, a novel BH3-only protein, regulates apoptosis at the endoplasmic reticulum. FASEB J 17 6 (2003) 696-698
-
(2003)
FASEB J
, vol.17
, Issue.6
, pp. 696-698
-
-
Mund, T.1
Gewies, A.2
Schoenfeld, N.3
Bauer, M.K.4
Grimm, S.5
-
48
-
-
0030970085
-
Harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)
-
Inohara N., Ding L., Chen S., and Nunez G. Harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L). EMBO J 16 7 (1997) 1686-1694
-
(1997)
EMBO J
, vol.16
, Issue.7
, pp. 1686-1694
-
-
Inohara, N.1
Ding, L.2
Chen, S.3
Nunez, G.4
-
49
-
-
0035903220
-
Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranes
-
Basanez G., Zhang J., Chau B.N., Maksaev G.I., Frolov V.A., Brandt T.A., et al. Pro-apoptotic cleavage products of Bcl-xL form cytochrome c-conducting pores in pure lipid membranes. J Biol Chem 276 33 (2001) 31083-31091
-
(2001)
J Biol Chem
, vol.276
, Issue.33
, pp. 31083-31091
-
-
Basanez, G.1
Zhang, J.2
Chau, B.N.3
Maksaev, G.I.4
Frolov, V.A.5
Brandt, T.A.6
-
50
-
-
0033597785
-
Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c
-
Kirsch D.G., Doseff A., Chau B.N., Lim D.S., de Souza-Pinto N.C., Hansford R., et al. Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. J Biol Chem 274 30 (1999) 21155-21161
-
(1999)
J Biol Chem
, vol.274
, Issue.30
, pp. 21155-21161
-
-
Kirsch, D.G.1
Doseff, A.2
Chau, B.N.3
Lim, D.S.4
de Souza-Pinto, N.C.5
Hansford, R.6
-
51
-
-
0032481346
-
The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4
-
Huang D.C., Adams J.M., and Cory S. The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4. EMBO J 17 4 (1998) 1029-1039
-
(1998)
EMBO J
, vol.17
, Issue.4
, pp. 1029-1039
-
-
Huang, D.C.1
Adams, J.M.2
Cory, S.3
-
52
-
-
0034724190
-
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
-
Shimizu S., Konishi A., Kodama T., and Tsujimoto Y. BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death. Proc Natl Acad Sci USA 97 7 (2000) 3100-3105
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.7
, pp. 3100-3105
-
-
Shimizu, S.1
Konishi, A.2
Kodama, T.3
Tsujimoto, Y.4
-
53
-
-
33645988546
-
TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo
-
Hotchkiss R.S., McConnell K.W., Bullok K., Davis C.G., Chang K.C., Schwulst S.J., et al. TAT-BH4 and TAT-Bcl-xL peptides protect against sepsis-induced lymphocyte apoptosis in vivo. J Immunol 176 9 (2006) 5471-5477
-
(2006)
J Immunol
, vol.176
, Issue.9
, pp. 5471-5477
-
-
Hotchkiss, R.S.1
McConnell, K.W.2
Bullok, K.3
Davis, C.G.4
Chang, K.C.5
Schwulst, S.J.6
-
54
-
-
33846781454
-
TAT-BH4 counteracts Abeta toxicity on capillary endothelium
-
Cantara S., Thorpe P.E., Ziche M., and Donnini S. TAT-BH4 counteracts Abeta toxicity on capillary endothelium. FEBS Lett 581 4 (2007) 702-706
-
(2007)
FEBS Lett
, vol.581
, Issue.4
, pp. 702-706
-
-
Cantara, S.1
Thorpe, P.E.2
Ziche, M.3
Donnini, S.4
-
55
-
-
0346753589
-
BH4-domain peptide from Bcl-x(L) exerts anti-apoptotic activity in vivo
-
Sugioka R., Shimizu S., Funatsu T., Tamagawa H., Sawa Y., Kawakami T., et al. BH4-domain peptide from Bcl-x(L) exerts anti-apoptotic activity in vivo. Oncogene 22 52 (2003) 8432-8440
-
(2003)
Oncogene
, vol.22
, Issue.52
, pp. 8432-8440
-
-
Sugioka, R.1
Shimizu, S.2
Funatsu, T.3
Tamagawa, H.4
Sawa, Y.5
Kawakami, T.6
-
56
-
-
42049091619
-
Unique biology of Mcl-1: therapeutic opportunities in cancer
-
Warr M.R., and Shore G.C. Unique biology of Mcl-1: therapeutic opportunities in cancer. Curr Mol Med 8 2 (2008) 138-147
-
(2008)
Curr Mol Med
, vol.8
, Issue.2
, pp. 138-147
-
-
Warr, M.R.1
Shore, G.C.2
-
57
-
-
33646846666
-
Mcl-1 interacts with truncated bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis
-
Clohessy J.G., Zhuang J.G., de Boer J., Gil-Gomez G., and Brady H.J.M. Mcl-1 interacts with truncated bid and inhibits its induction of cytochrome c release and its role in receptor-mediated apoptosis. J Biol Chem 281 9 (2006) 5750-5759
-
(2006)
J Biol Chem
, vol.281
, Issue.9
, pp. 5750-5759
-
-
Clohessy, J.G.1
Zhuang, J.G.2
de Boer, J.3
Gil-Gomez, G.4
Brady, H.J.M.5
-
58
-
-
44349182097
-
Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1
-
Zhai D.Y., Jin C.F., Huang Z.W., Satterthwait A.C., and Reed J.C. Differential regulation of Bax and Bak by anti-apoptotic Bcl-2 family proteins Bcl-B and Mcl-1. J Biol Chem 283 15 (2008) 9580-9586
-
(2008)
J Biol Chem
, vol.283
, Issue.15
, pp. 9580-9586
-
-
Zhai, D.Y.1
Jin, C.F.2
Huang, Z.W.3
Satterthwait, A.C.4
Reed, J.C.5
-
59
-
-
39849108605
-
Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist
-
Simmons M.J., Fan G., Zong W.X., Degenhardt K., White E., and Gelinas C. Bfl-1/A1 functions, similar to Mcl-1, as a selective tBid and Bak antagonist. Oncogene 27 10 (2008) 1421-1428
-
(2008)
Oncogene
, vol.27
, Issue.10
, pp. 1421-1428
-
-
Simmons, M.J.1
Fan, G.2
Zong, W.X.3
Degenhardt, K.4
White, E.5
Gelinas, C.6
-
60
-
-
3142652618
-
BOK and NOXA are essential mediators of p53-dependent apoptosis
-
Yakovlev A.G., Di Giovanni S., Wang G.P., Liu W.F., Stoica B., and Faden A.I. BOK and NOXA are essential mediators of p53-dependent apoptosis. J Biol Chem 279 27 (2004) 28367-28374
-
(2004)
J Biol Chem
, vol.279
, Issue.27
, pp. 28367-28374
-
-
Yakovlev, A.G.1
Di Giovanni, S.2
Wang, G.P.3
Liu, W.F.4
Stoica, B.5
Faden, A.I.6
-
61
-
-
0001003612
-
Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members
-
Hsu S.Y., Kaipia A., Mcgee E., Lomeli M., and Hsueh A.J.W. Bok is a pro-apoptotic Bcl-2 protein with restricted expression in reproductive tissues and heterodimerizes with selective anti-apoptotic Bcl-2 family members. Proc Natl Acad Sci USA 94 23 (1997) 12401-12406
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.23
, pp. 12401-12406
-
-
Hsu, S.Y.1
Kaipia, A.2
Mcgee, E.3
Lomeli, M.4
Hsueh, A.J.W.5
-
62
-
-
0032502776
-
Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL
-
Inohara N., Ekhterae D., Garcia I., Carrio R., Merino J., Merry A., et al. Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL. J Biol Chem 273 15 (1998) 8705-8710
-
(1998)
J Biol Chem
, vol.273
, Issue.15
, pp. 8705-8710
-
-
Inohara, N.1
Ekhterae, D.2
Garcia, I.3
Carrio, R.4
Merino, J.5
Merry, A.6
-
63
-
-
0028113218
-
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins
-
Boyd J.M., Malstrom S., Subramanian T., Venkatesh L.K., Schaeper U., Elangovan B., et al. Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79 2 (1994) 341-351
-
(1994)
Cell
, vol.79
, Issue.2
, pp. 341-351
-
-
Boyd, J.M.1
Malstrom, S.2
Subramanian, T.3
Venkatesh, L.K.4
Schaeper, U.5
Elangovan, B.6
-
64
-
-
0033942613
-
BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore
-
Vande Velde C., Cizeau J., Dubik D., Alimonti J., Brown T., Israels S., et al. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol 20 15 (2000) 5454-5468
-
(2000)
Mol Cell Biol
, vol.20
, Issue.15
, pp. 5454-5468
-
-
Vande Velde, C.1
Cizeau, J.2
Dubik, D.3
Alimonti, J.4
Brown, T.5
Israels, S.6
-
65
-
-
0033984094
-
BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites
-
Ray R., Chen G., Vande V.C., Cizeau J., Park J.H., Reed J.C., et al. BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites. J Biol Chem 275 2 (2000) 1439-1448
-
(2000)
J Biol Chem
, vol.275
, Issue.2
, pp. 1439-1448
-
-
Ray, R.1
Chen, G.2
Vande, V.C.3
Cizeau, J.4
Park, J.H.5
Reed, J.C.6
-
66
-
-
0032932923
-
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins
-
Chen G., Cizeau J., Vande V.C., Park J.H., Bozek G., Bolton J., et al. Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J Biol Chem 274 1 (1999) 7-10
-
(1999)
J Biol Chem
, vol.274
, Issue.1
, pp. 7-10
-
-
Chen, G.1
Cizeau, J.2
Vande, V.C.3
Park, J.H.4
Bozek, G.5
Bolton, J.6
-
67
-
-
0037085244
-
The carboxy terminal C-tail of BNip3 is crucial in induction of mitochondrial permeability transition in isolated mitochondria
-
Kim J.Y., Cho J.J., Ha J., and Park J.H. The carboxy terminal C-tail of BNip3 is crucial in induction of mitochondrial permeability transition in isolated mitochondria. Arch Biochem Biophys 398 2 (2002) 147-152
-
(2002)
Arch Biochem Biophys
, vol.398
, Issue.2
, pp. 147-152
-
-
Kim, J.Y.1
Cho, J.J.2
Ha, J.3
Park, J.H.4
-
68
-
-
43949125194
-
Mitochondrial autophagy: life and breath of the cell
-
Semenza G.L. Mitochondrial autophagy: life and breath of the cell. Autophagy 4 4 (2008) 534-536
-
(2008)
Autophagy
, vol.4
, Issue.4
, pp. 534-536
-
-
Semenza, G.L.1
-
69
-
-
0035377522
-
Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension
-
Kataoka T., Holler N., Micheau O., Martinon F., Tinel A., Hofmann K., et al. Bcl-rambo, a novel Bcl-2 homologue that induces apoptosis via its unique C-terminal extension. J Biol Chem 276 22 (2001) 19548-19554
-
(2001)
J Biol Chem
, vol.276
, Issue.22
, pp. 19548-19554
-
-
Kataoka, T.1
Holler, N.2
Micheau, O.3
Martinon, F.4
Tinel, A.5
Hofmann, K.6
-
70
-
-
0035951886
-
Bcl-G, a novel pro-apoptotic member of the Bcl-2 family
-
Guo B., Godzik A., and Reed J.C. Bcl-G, a novel pro-apoptotic member of the Bcl-2 family. J Biol Chem 276 4 (2001) 2780-2785
-
(2001)
J Biol Chem
, vol.276
, Issue.4
, pp. 2780-2785
-
-
Guo, B.1
Godzik, A.2
Reed, J.C.3
-
71
-
-
0038702644
-
Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region
-
Coultas L., Pellegrini M., Visvader J.E., Lindeman G.J., Chen L., Adams J.M., et al. Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region. Cell Death Differ 10 2 (2003) 185-192
-
(2003)
Cell Death Differ
, vol.10
, Issue.2
, pp. 185-192
-
-
Coultas, L.1
Pellegrini, M.2
Visvader, J.E.3
Lindeman, G.J.4
Chen, L.5
Adams, J.M.6
-
72
-
-
35148815554
-
Bim and the pro-survival bcl-2 proteins - opposites attract, ERK repels
-
Ewings K.E., Wiggins C.M., and Cook S.J. Bim and the pro-survival bcl-2 proteins - opposites attract, ERK repels. Cell Cycle 6 18 (2007) 2236-2240
-
(2007)
Cell Cycle
, vol.6
, Issue.18
, pp. 2236-2240
-
-
Ewings, K.E.1
Wiggins, C.M.2
Cook, S.J.3
-
73
-
-
4644299291
-
Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications
-
Akgul C., Moulding D.A., and Edwards S.W. Alternative splicing of Bcl-2-related genes: functional consequences and potential therapeutic applications. Cell Mol Life Sci 61 17 (2004) 2189-2199
-
(2004)
Cell Mol Life Sci
, vol.61
, Issue.17
, pp. 2189-2199
-
-
Akgul, C.1
Moulding, D.A.2
Edwards, S.W.3
-
74
-
-
0027282044
-
Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
-
Boise L.H., Gonzalez-Garcia M., Postema C.E., Ding L., Lindsten T., Turka L.A., et al. Bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 74 4 (1993) 597-608
-
(1993)
Cell
, vol.74
, Issue.4
, pp. 597-608
-
-
Boise, L.H.1
Gonzalez-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
-
75
-
-
2542584622
-
Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation
-
Schmitt E., Paquet C., Beauchemin M., and Bertrand R. Bcl-xES, a BH4- and BH2-containing antiapoptotic protein, delays Bax oligomer formation and binds Apaf-1, blocking procaspase-9 activation. Oncogene 23 22 (2004) 3915-3931
-
(2004)
Oncogene
, vol.23
, Issue.22
, pp. 3915-3931
-
-
Schmitt, E.1
Paquet, C.2
Beauchemin, M.3
Bertrand, R.4
-
76
-
-
33645730665
-
A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain
-
Hossini A.M., Geilen C.C., Fecker L.F., Daniel P.T., and Eberle J. A novel Bcl-x splice product, Bcl-xAK, triggers apoptosis in human melanoma cells without BH3 domain. Oncogene 25 15 (2006) 2160-2169
-
(2006)
Oncogene
, vol.25
, Issue.15
, pp. 2160-2169
-
-
Hossini, A.M.1
Geilen, C.C.2
Fecker, L.F.3
Daniel, P.T.4
Eberle, J.5
-
77
-
-
0028206341
-
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax
-
Yin X.M., Oltvai Z.N., and Korsmeyer S.J. BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax. Nature 369 6478 (1994) 321-323
-
(1994)
Nature
, vol.369
, Issue.6478
, pp. 321-323
-
-
Yin, X.M.1
Oltvai, Z.N.2
Korsmeyer, S.J.3
-
78
-
-
0030614915
-
Structure of Bcl-x(L)-Bak peptide complex: recognition between regulators of apoptosis
-
Sattler M., Liang H., Nettesheim D., Meadows R.P., Harlan J.E., Eberstadt M., et al. Structure of Bcl-x(L)-Bak peptide complex: recognition between regulators of apoptosis. Science 275 5302 (1997) 983-986
-
(1997)
Science
, vol.275
, Issue.5302
, pp. 983-986
-
-
Sattler, M.1
Liang, H.2
Nettesheim, D.3
Meadows, R.P.4
Harlan, J.E.5
Eberstadt, M.6
-
79
-
-
0034769833
-
Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L)
-
Mitra R.S., Benedict M.A., Qian D., Foreman K.E., Ekhterae D., Nickoloff B.J., et al. Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L). Neoplasia 3 5 (2001) 437-445
-
(2001)
Neoplasia
, vol.3
, Issue.5
, pp. 437-445
-
-
Mitra, R.S.1
Benedict, M.A.2
Qian, D.3
Foreman, K.E.4
Ekhterae, D.5
Nickoloff, B.J.6
-
80
-
-
0142138711
-
Conditional expression of exogenous Bcl-X-s triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts
-
Hossini A.M., Eberle R., Fecker L.F., Orfanos C.E., and Geilen C.C. Conditional expression of exogenous Bcl-X-s triggers apoptosis in human melanoma cells in vitro and delays growth of melanoma xenografts. FEBS Lett 553 3 (2003) 250-256
-
(2003)
FEBS Lett
, vol.553
, Issue.3
, pp. 250-256
-
-
Hossini, A.M.1
Eberle, R.2
Fecker, L.F.3
Orfanos, C.E.4
Geilen, C.C.5
-
81
-
-
0031008397
-
Channel formation by antiapoptotic protein Bcl-2
-
Schendel S.L., Xie Z., Montal M.O., Matsuyama S., Montal M., and Reed J.C. Channel formation by antiapoptotic protein Bcl-2. Proc Natl Acad Sci USA 94 10 (1997) 5113-5118
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.10
, pp. 5113-5118
-
-
Schendel, S.L.1
Xie, Z.2
Montal, M.O.3
Matsuyama, S.4
Montal, M.5
Reed, J.C.6
-
82
-
-
0034641676
-
NMR studies of the anti-apoptotic protein Bcl-xL in micelles
-
Losonczi J.A., Olejniczak E.T., Betz S.F., Harlan J.E., Mack J., and Fesik S.W. NMR studies of the anti-apoptotic protein Bcl-xL in micelles. Biochemistry 39 36 (2000) 11024-11033
-
(2000)
Biochemistry
, vol.39
, Issue.36
, pp. 11024-11033
-
-
Losonczi, J.A.1
Olejniczak, E.T.2
Betz, S.F.3
Harlan, J.E.4
Mack, J.5
Fesik, S.W.6
-
83
-
-
41349099104
-
Cancer statistics
-
Jemal A., Siegel R., Ward E., Hao Y.P., Xu J.Q., Murray T., et al. Cancer statistics. CA Cancer J Clin 58 2 (2008) 71-96
-
(2008)
CA Cancer J Clin
, vol.58
, Issue.2
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.P.4
Xu, J.Q.5
Murray, T.6
-
84
-
-
44949192861
-
Making progress against cancer in Europe in 2008
-
Albreht T., McKee M., Alexe D.M., Coleman M.P., and Martin-Moreno J.M. Making progress against cancer in Europe in 2008. Eur J Cancer PMID (2008) 18353629
-
(2008)
Eur J Cancer PMID
, pp. 18353629
-
-
Albreht, T.1
McKee, M.2
Alexe, D.M.3
Coleman, M.P.4
Martin-Moreno, J.M.5
|