-
1
-
-
0030826929
-
-
Rothenberg M.L. Topoisomerase I inhibitors: review and update. Ann Oncol, 8: 837-855, 1997.
-
Rothenberg M.L. Topoisomerase I inhibitors: review and update. Ann Oncol, 8: 837-855, 1997.
-
-
-
-
2
-
-
0022340594
-
Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I
-
Hsiang Y.H., Hertzberg R., Hecht S., Liu L.F. Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I. J Biol Chem, 260: 14873-14878, 1985.
-
(1985)
J Biol Chem
, vol.260
, pp. 14873-14878
-
-
Hsiang, Y.H.1
Hertzberg, R.2
Hecht, S.3
Liu, L.F.4
-
3
-
-
29144494850
-
Phase II study of weekly irinotecan plus capecitabine for chemotherapy-naive patients with advanced nonsmall cell lung carcinoma
-
Han J.Y., Lee D.H., Lee S.Y., Park C.G., Kim H.Y., Lee H.G., Lee J.J., Kim H.T., Lee J.S. Phase II study of weekly irinotecan plus capecitabine for chemotherapy-naive patients with advanced nonsmall cell lung carcinoma. Cancer, 104: 2759-2765, 2005.
-
(2005)
Cancer
, vol.104
, pp. 2759-2765
-
-
Han, J.Y.1
Lee, D.H.2
Lee, S.Y.3
Park, C.G.4
Kim, H.Y.5
Lee, H.G.6
Lee, J.J.7
Kim, H.T.8
Lee, J.S.9
-
4
-
-
27644502351
-
Topotecan as second-line therapy for ovarian cancer: Dosage versus toxicity
-
Markman M. Topotecan as second-line therapy for ovarian cancer: dosage versus toxicity. Oncologist, 10: 695-697, 2005.
-
(2005)
Oncologist
, vol.10
, pp. 695-697
-
-
Markman, M.1
-
5
-
-
24644462203
-
A phase I study and pharmacologic evaluation of irinotecan and carboplatin for patients with advanced ovarian carcinoma who previously received platinum-containing chemotherapy
-
Yonemori K., Katsumata N., Yamamoto N., Kasamatsu T., Yamada T., Tsunematsu R., Fujiwara Y. A phase I study and pharmacologic evaluation of irinotecan and carboplatin for patients with advanced ovarian carcinoma who previously received platinum-containing chemotherapy. Cancer, 104: 1204-1212, 2005.
-
(2005)
Cancer
, vol.104
, pp. 1204-1212
-
-
Yonemori, K.1
Katsumata, N.2
Yamamoto, N.3
Kasamatsu, T.4
Yamada, T.5
Tsunematsu, R.6
Fujiwara, Y.7
-
6
-
-
0024537205
-
Modification of the hydroxy lactone ring of camptothecinFinhibition of mammalian topoisomerase-I and biological activity
-
Hertzberg R.P., Caranfa M.J., Holden K.G., Jakas D.R., Gallagher G., Mattern M.R., Mong S.M., Bartus J.O., Johnson R.K., Kingsbury W.D. Modification of the hydroxy lactone ring of camptothecinFinhibition of mammalian topoisomerase-I and biological activity. J Med Chem, 32: 715-720, 1989.
-
(1989)
J Med Chem
, vol.32
, pp. 715-720
-
-
Hertzberg, R.P.1
Caranfa, M.J.2
Holden, K.G.3
Jakas, D.R.4
Gallagher, G.5
Mattern, M.R.6
Mong, S.M.7
Bartus, J.O.8
Johnson, R.K.9
Kingsbury, W.D.10
-
7
-
-
0027930186
-
Differential interactions of camptothecin lactone and carboxylate forms with human blood components
-
Mi, Z., Burke, T.G.Differential interactions of camptothecin lactone and carboxylate forms with human blood components. Biochemistry, 33: 10325-10336, 1994.
-
(1994)
Biochemistry
, vol.33
, pp. 10325-10336
-
-
Mi, Z.1
Burke, T.G.2
-
8
-
-
0018901322
-
-
Wani M.C., Ronman P.E., Lindley J.T., Wall M.E. Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues. J Med Chem, 3: 554-560, 1980.
-
Wani M.C., Ronman P.E., Lindley J.T., Wall M.E. Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues. J Med Chem, 3: 554-560, 1980.
-
-
-
-
9
-
-
0027201885
-
Preferential binding of the carboxylate form of camptothecin by human serum albumin
-
Burke T.G., Mi Z.H. Preferential binding of the carboxylate form of camptothecin by human serum albumin. Anal Biochem, 212: 285-287, 1993.
-
(1993)
Anal Biochem
, vol.212
, pp. 285-287
-
-
Burke, T.G.1
Mi, Z.H.2
-
10
-
-
1542330612
-
Subcellular localization of the camptothecin analogues, topotecan and gimatecan
-
Croce A.C., Bottiroli G., Supino R., Favini E., Zuco V., Zunino F. Subcellular localization of the camptothecin analogues, topotecan and gimatecan. Biochem Pharmacol, 67: 1035-1045, 2004.
-
(2004)
Biochem Pharmacol
, vol.67
, pp. 1035-1045
-
-
Croce, A.C.1
Bottiroli, G.2
Supino, R.3
Favini, E.4
Zuco, V.5
Zunino, F.6
-
11
-
-
8344283579
-
Cytotoxic effect of different camptothecin formulations on human colon carcinoma in vitro
-
Sætern A.M., Brandl M., Bakkelund W.H., Sveinbjørnsson B. Cytotoxic effect of different camptothecin formulations on human colon carcinoma in vitro. Anti-Cancer Drugs, 15: 899-906, 2004.
-
(2004)
Anti-Cancer Drugs
, vol.15
, pp. 899-906
-
-
Sætern, A.M.1
Brandl, M.2
Bakkelund, W.H.3
Sveinbjørnsson, B.4
-
12
-
-
23344444244
-
Tumor-targeted and activated bioconjugates for improved camptothecin delivery
-
Paranjpe P.V., Stein S., Sinko P.J. Tumor-targeted and activated bioconjugates for improved camptothecin delivery. Anti-Cancer Drugs, 16: 763-775, 2005.
-
(2005)
Anti-Cancer Drugs
, vol.16
, pp. 763-775
-
-
Paranjpe, P.V.1
Stein, S.2
Sinko, P.J.3
-
13
-
-
0036354863
-
Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethyleneglycol) conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells
-
Minko T., Paranjpe P.V., Qiu B., Lalloo A., Won R., Sinko P.J. Enhancing the anticancer efficacy of camptothecin using biotinylated poly(ethyleneglycol) conjugates in sensitive and multidrug-resistant human ovarian carcinoma cells. Cancer Chemother Pharmacol, 50: 143-150, 2002.
-
(2002)
Cancer Chemother Pharmacol
, vol.50
, pp. 143-150
-
-
Minko, T.1
Paranjpe, P.V.2
Qiu, B.3
Lalloo, A.4
Won, R.5
Sinko, P.J.6
-
14
-
-
0141955909
-
Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors
-
Williams J., Lansdown R., Sweitzer R., Romanowski M., LaBell R., Ramaswami R., Unger E. Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors. J Control Release, 9: 167-172, 2003.
-
(2003)
J Control Release
, vol.9
, pp. 167-172
-
-
Williams, J.1
Lansdown, R.2
Sweitzer, R.3
Romanowski, M.4
LaBell, R.5
Ramaswami, R.6
Unger, E.7
-
15
-
-
0034908665
-
Effects of 10-hydroxycamptothecin, delivered from locally injectable poly(lactide-co-glycolide) microspheres, in a murine human oral squamous cell carcinoma regression model
-
Mallery S.R., Shenderova A., Pei P., Begum S., Ciminieri J.R., Wilson R.F., Casto B.C., Schuller D.E., Morse M.A. Effects of 10-hydroxycamptothecin, delivered from locally injectable poly(lactide-co-glycolide) microspheres, in a murine human oral squamous cell carcinoma regression model. Anticancer Res, 21: 1713-1722, 2001.
-
(2001)
Anticancer Res
, vol.21
, pp. 1713-1722
-
-
Mallery, S.R.1
Shenderova, A.2
Pei, P.3
Begum, S.4
Ciminieri, J.R.5
Wilson, R.F.6
Casto, B.C.7
Schuller, D.E.8
Morse, M.A.9
-
16
-
-
33646403692
-
Development and validation of a sensitive reversed-phase HPLC method to determine intracellular accumulation of hydroxycamptothecin
-
Zhao Y.X., Gao J.Q., Qiao H.L., Chen H.L., Liang W.Q. Development and validation of a sensitive reversed-phase HPLC method to determine intracellular accumulation of hydroxycamptothecin. J Pharm Biomed Anal, 41: 1007-1010, 2006.
-
(2006)
J Pharm Biomed Anal
, vol.41
, pp. 1007-1010
-
-
Zhao, Y.X.1
Gao, J.Q.2
Qiao, H.L.3
Chen, H.L.4
Liang, W.Q.5
-
17
-
-
0037426690
-
A lipophilic paclitaxel derivative incorporated in a lipid emulsion for parenteral administration
-
Lundberg B.B., Risovic V., Ramaswamy M., Wasan K.M. A lipophilic paclitaxel derivative incorporated in a lipid emulsion for parenteral administration. J Control Release, 86: 93-100, 2003.
-
(2003)
J Control Release
, vol.86
, pp. 93-100
-
-
Lundberg, B.B.1
Risovic, V.2
Ramaswamy, M.3
Wasan, K.M.4
-
18
-
-
0141703401
-
An assessment of techniques for evaluating the physical stability of parenteral emulsions
-
Zhang X.G., Kirsch L.E. An assessment of techniques for evaluating the physical stability of parenteral emulsions. PDA. J Pharm Sci Technol, 57: 300-315, 2003.
-
(2003)
PDA. J Pharm Sci Technol
, vol.57
, pp. 300-315
-
-
Zhang, X.G.1
Kirsch, L.E.2
-
19
-
-
0033379879
-
In vitro cellular accumulation and cytotoxicity of liposomal and conventional formulations of daunorubicin and doxorubicin in resistant K562 cells
-
Wang Y., Eksborg S., Lewensohn R., Lindberg A., Liliemark E. In vitro cellular accumulation and cytotoxicity of liposomal and conventional formulations of daunorubicin and doxorubicin in resistant K562 cells. Anticancer Drugs, 10:921-928, 1999.
-
(1999)
Anticancer Drugs
, vol.10
, pp. 921-928
-
-
Wang, Y.1
Eksborg, S.2
Lewensohn, R.3
Lindberg, A.4
Liliemark, E.5
-
20
-
-
33750056080
-
-
Serpe L., Guido M., Canaparo R., Muntoni E., Cavalli R., Panzanelli P., Della Pepal C., Bargoni A., Mauro A., Gasco MR., Eandi M., Zara GP.Intracellular accumulation and cytotoxicity of doxorubicin with different pharmaceutical formulations in human cancer cell lines. J Nanosci Nanotechnol, 6(9-10):3062-3069, 2006.
-
Serpe L., Guido M., Canaparo R., Muntoni E., Cavalli R., Panzanelli P., Della Pepal C., Bargoni A., Mauro A., Gasco MR., Eandi M., Zara GP.Intracellular accumulation and cytotoxicity of doxorubicin with different pharmaceutical formulations in human cancer cell lines. J Nanosci Nanotechnol, 6(9-10):3062-3069, 2006.
-
-
-
-
21
-
-
21244494846
-
Enhanced intracellular uptake of sterically stabilized liposomal Doxorubicin in vitro resulting in improved antitumor activity in vivo
-
Xiong X.B., Huang Y., Lu W.L., Zhang H., Zhang X., Zhang Q. Enhanced intracellular uptake of sterically stabilized liposomal Doxorubicin in vitro resulting in improved antitumor activity in vivo. Pharm Res, 22(6):933-939, 2005.
-
(2005)
Pharm Res
, vol.22
, Issue.6
, pp. 933-939
-
-
Xiong, X.B.1
Huang, Y.2
Lu, W.L.3
Zhang, H.4
Zhang, X.5
Zhang, Q.6
-
22
-
-
0037687903
-
Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro
-
Shabbits J.A., Mayer L.D. Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro. Biochim Biophys Acta, 1612: 98-106, 2003.
-
(2003)
Biochim Biophys Acta
, vol.1612
, pp. 98-106
-
-
Shabbits, J.A.1
Mayer, L.D.2
-
23
-
-
0031800370
-
-
van, Ark-Otte J., Kedde M.A., van, der, Vijgh W.J., Dingemans A.M., Jansen W.J., Pinedo H.M., Boven E., Giaccone G. Determinants of CPT-11 and SN-38 activities in human lung cancer cells. Br J Cancer, 77: 2171-2176, 1998.
-
van, Ark-Otte J., Kedde M.A., van, der, Vijgh W.J., Dingemans A.M., Jansen W.J., Pinedo H.M., Boven E., Giaccone G. Determinants of CPT-11 and SN-38 activities in human lung cancer cells. Br J Cancer, 77: 2171-2176, 1998.
-
-
-
-
24
-
-
0030856115
-
Cellular pharmacokinetics and cytotoxicity of camptothecin and topotecan at normal and acidic pH
-
Gabr A., Kuin A., Aalders M., El-Gawly H., Smets L.A. Cellular pharmacokinetics and cytotoxicity of camptothecin and topotecan at normal and acidic pH. Cancer Res, 57: 4811-4816, 1997.
-
(1997)
Cancer Res
, vol.57
, pp. 4811-4816
-
-
Gabr, A.1
Kuin, A.2
Aalders, M.3
El-Gawly, H.4
Smets, L.A.5
-
25
-
-
3142729057
-
-
Pratesi G., Beretta G.L., Zunino F. Gimatecan, a novel camptothecin with a promising preclinical profile. Anticancer Drugs, 15: 545-552, 2004.
-
Pratesi G., Beretta G.L., Zunino F. Gimatecan, a novel camptothecin with a promising preclinical profile. Anticancer Drugs, 15: 545-552, 2004.
-
-
-
-
26
-
-
0037072576
-
Prospects for cationic polymers in gene and oligonucleotide therapy against cancer
-
Merdan T., Kopecek J., Kissel T. Prospects for cationic polymers in gene and oligonucleotide therapy against cancer. Adv Drug Deliv Rev, 54: 715-758, 2002.
-
(2002)
Adv Drug Deliv Rev
, vol.54
, pp. 715-758
-
-
Merdan, T.1
Kopecek, J.2
Kissel, T.3
-
27
-
-
0028037175
-
Polyethylene glycol modified phospholipids stabilize emulsions prepared from triacylglycerol
-
Wheeler J.J., Wong K.F., Ansell S.M., Masin D., Bally M.B. Polyethylene glycol modified phospholipids stabilize emulsions prepared from triacylglycerol. J Pharm Sci, 83: 1558-1564, 1994.
-
(1994)
J Pharm Sci
, vol.83
, pp. 1558-1564
-
-
Wheeler, J.J.1
Wong, K.F.2
Ansell, S.M.3
Masin, D.4
Bally, M.B.5
-
28
-
-
0033947102
-
Electrophoretic mobility shift assay for the detection of specific DNA-protein complex in nuclear extracts from the cultured cells and frozen autopsy human brain tissue
-
Lahiri D.K., Ge Y. Electrophoretic mobility shift assay for the detection of specific DNA-protein complex in nuclear extracts from the cultured cells and frozen autopsy human brain tissue. Brain Res Brain Res Protoc, 5: 257-265, 2000.
-
(2000)
Brain Res Brain Res Protoc
, vol.5
, pp. 257-265
-
-
Lahiri, D.K.1
Ge, Y.2
-
29
-
-
34247842638
-
-
Spector D.; Goldman R.; Leinwand L., Cells: A Laboratory Manual 1: Culture and Biochemical Analysis of cells. Cold Spring Harbor Laboratory Press, USA, 1997.
-
Spector D.; Goldman R.; Leinwand L., Cells: A Laboratory Manual Volume 1: Culture and Biochemical Analysis of cells. Cold Spring Harbor Laboratory Press, USA, 1997.
-
-
-
-
30
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assay
-
Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assay. J Immunol Methods, 65: 55-63, 1983.
-
(1983)
J Immunol Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
31
-
-
0033043628
-
The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins
-
Shenderova, A., Burke, T.G., Schwendeman, S.P. The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins. Pharm Res, 16: 241-248, 1999
-
(1999)
Pharm Res
, vol.16
, pp. 241-248
-
-
Shenderova, A.1
Burke, T.G.2
Schwendeman, S.P.3
-
32
-
-
27244447364
-
Mechanisms and functional aspects of multidrug resistance in Ehrlichascites tumour cells
-
Nielsen D.L. Mechanisms and functional aspects of multidrug resistance in Ehrlichascites tumour cells. Dan Med Bull, 51: 393-414, 2004.
-
(2004)
Dan Med Bull
, vol.51
, pp. 393-414
-
-
Nielsen, D.L.1
-
33
-
-
0035048881
-
Optimization of lipid composition in cationic emulsion as in vitro and in vivo transfection agents
-
Kim T.W., Chung H., Kwon I.C., Sung H.C., Jeong S.Y. Optimization of lipid composition in cationic emulsion as in vitro and in vivo transfection agents. Pharm Res, 18: 54-60, 2001.
-
(2001)
Pharm Res
, vol.18
, pp. 54-60
-
-
Kim, T.W.1
Chung, H.2
Kwon, I.C.3
Sung, H.C.4
Jeong, S.Y.5
-
34
-
-
4444313274
-
Improved gene expression pattern using Epstein-Barr virus (EBV)-based plasmid and cationic emulsion
-
Min K.A., Lee S.K., Kim C.K. Improved gene expression pattern using Epstein-Barr virus (EBV)-based plasmid and cationic emulsion. Biomaterials, 26: 1063-1070, 2005.
-
(2005)
Biomaterials
, vol.26
, pp. 1063-1070
-
-
Min, K.A.1
Lee, S.K.2
Kim, C.K.3
-
35
-
-
17644386496
-
Polycations enhance emulsion-mediated in vitro and in vivo transfection
-
Kim T.W., Chung H., Kwon I.C., Sung H.C., Jeong S.Y. Polycations enhance emulsion-mediated in vitro and in vivo transfection. Int J Pharm, 295: 35-45, 2005.
-
(2005)
Int J Pharm
, vol.295
, pp. 35-45
-
-
Kim, T.W.1
Chung, H.2
Kwon, I.C.3
Sung, H.C.4
Jeong, S.Y.5
|