The mitotic-arresting and apoptosis-inducing effects of diosgenyl saponins on human leukemia cell lines

Biological and Pharmaceutical Bulletin

Volumn 27, Issue 7, 2004, Pages 1059-1065

  Liu, Ming Jie ^a   Wang, Zhao ^a   Ju, Yong ^a   Zhou, Jiang Bing ^a   Wang, Yu ^a   Wong, Ricky Ngok Shun ^b  

^a TSINGHUA UNIVERSITY   (China)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Apoptosis; Dioscin; Diosgenin; Diosgenyl saponin; Mitotic arrest; Trillin

Indexed keywords

DIOSCIN; DIOSGENIN; PHOSPHATIDYLSERINE; PROTEIN HYDROLYSATE; SAPOGENIN; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; PLANT EXTRACT; SAPONIN;

APOPTOSIS; ARTICLE; CELL LINE; CELL STRAIN HL 60; CELL STRUCTURE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOSIS INHIBITION; MYELOID LEUKEMIA; STAINING; CELL CYCLE; CELL STRAIN K 562; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; ISOLATION AND PURIFICATION; LEUKEMIA; MITOSIS; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; K562 CELLS; LEUKEMIA; MITOSIS; PLANT EXTRACTS; SAPONINS;

EID: 14844347909     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.27.1059     Document Type: Article

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