-
1
-
-
77049189428
-
The distribution of substance P and serotonin in the central nervous system of the dog.
-
Amin AH, Crawford TBB, Gaddum JH. The distribution of substance P and serotonin in the central nervous system of the dog. J Physiol (Lond) 1954, 126:596-618.
-
(1954)
J Physiol (Lond)
, vol.126
, pp. 596-618
-
-
Amin, A.H.1
Crawford, T.B.B.2
Gaddum, J.H.3
-
2
-
-
0032970989
-
A review of central 5-HT receptors and their function.
-
Barnes NM, Sharp T. A review of central 5-HT receptors and their function. Neuropharmacology 1999, 38:1083-1152.
-
(1999)
Neuropharmacology
, vol.38
, pp. 1083-1152
-
-
Barnes, N.M.1
Sharp, T.2
-
3
-
-
2342513607
-
Recent advances in understanding serotonin regulation of cardiovascular function.
-
Cote F, Fligny C, Fromes Y, Mallet J, Vodjdani G. Recent advances in understanding serotonin regulation of cardiovascular function. Trends Mol Med 2004, 10:232-238.
-
(2004)
Trends Mol Med
, vol.10
, pp. 232-238
-
-
Cote, F.1
Fligny, C.2
Fromes, Y.3
Mallet, J.4
Vodjdani, G.5
-
7
-
-
0033018626
-
Activation of ρA by lysophosphatidic acid and Gα 12/13 subunits in neuronal cells: induction of neurite retraction.
-
Kranenburg O, Poland M, van Horck FPG, Drechsel D, Hall A, Moolenaar WH. Activation of ρA by lysophosphatidic acid and Gα 12/13 subunits in neuronal cells: induction of neurite retraction. Mol Biol Cell 1999, 10:1851-1857.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 1851-1857
-
-
Kranenburg, O.1
Poland, M.2
van Horck, F.P.G.3
Drechsel, D.4
Hall, A.5
Moolenaar, W.H.6
-
8
-
-
0026676807
-
Subunits βγ of heterotrimeric G protein activate β 2 isoform of phospholipase C.
-
Katz A, Wu D, Simon MI. Subunits βγ of heterotrimeric G protein activate β 2 isoform of phospholipase C. Nature 1992, 360:686-689.
-
(1992)
Nature
, vol.360
, pp. 686-689
-
-
Katz, A.1
Wu, D.2
Simon, M.I.3
-
9
-
-
0026418426
-
Type-specific regulation of adenylyl cyclase by G protein βγ subunits.
-
Tang WJ, Gilman AG. Type-specific regulation of adenylyl cyclase by G protein βγ subunits. Science 1991, 254:1500-1503.
-
(1991)
Science
, vol.254
, pp. 1500-1503
-
-
Tang, W.J.1
Gilman, A.G.2
-
10
-
-
0028334738
-
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits.
-
Stephens L, Smrcka A, Cooke FT, Jackson TR, Sternweis PC, Hawkins PT. A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits. Cell 1994, 77:83-93.
-
(1994)
Cell
, vol.77
, pp. 83-93
-
-
Stephens, L.1
Smrcka, A.2
Cooke, F.T.3
Jackson, T.R.4
Sternweis, P.C.5
Hawkins, P.T.6
-
11
-
-
0028987271
-
G βγ interactions with PH domains and Ras-MAPK signaling pathways.
-
Inglese J, Koch WJ, Touhara K, Lefkowitz RJ. G βγ interactions with PH domains and Ras-MAPK signaling pathways. Trends Biochem Sci 1995, 20:151-156.
-
(1995)
Trends Biochem Sci
, vol.20
, pp. 151-156
-
-
Inglese, J.1
Koch, W.J.2
Touhara, K.3
Lefkowitz, R.J.4
-
12
-
-
0023132940
-
The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart.
-
Logothetis DE, Kurachi Y, Galper J, Neer EJ, Clapham DE. The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart. Nature 1987, 325:321-326.
-
(1987)
Nature
, vol.325
, pp. 321-326
-
-
Logothetis, D.E.1
Kurachi, Y.2
Galper, J.3
Neer, E.J.4
Clapham, D.E.5
-
13
-
-
0029921401
-
Voltage-dependent modulation of N-type calcium channels by G-protein βγ subunits.
-
Ikeda SR. Voltage-dependent modulation of N-type calcium channels by G-protein βγ subunits. Nature 1996, 380:255-258.
-
(1996)
Nature
, vol.380
, pp. 255-258
-
-
Ikeda, S.R.1
-
14
-
-
0018231884
-
Characteristics of central 5-HT receptors and their adaptive changes following intracerebral 5,7-dihydroxytryptamine administration in the rat.
-
Nelson DL, Herbet A, Bourgoin S, Glowinski J, Hamon M. Characteristics of central 5-HT receptors and their adaptive changes following intracerebral 5, 7-dihydroxytryptamine administration in the rat. Mol Pharmacol 1978, 14:983-995.
-
(1978)
Mol Pharmacol
, vol.14
, pp. 983-995
-
-
Nelson, D.L.1
Herbet, A.2
Bourgoin, S.3
Glowinski, J.4
Hamon, M.5
-
15
-
-
0025582616
-
The central 5-HT1A receptors: pharmacological, biochemical, functional, and regulatory properties.
-
discussion
-
Hamon M, Gozlan H, el Mestikawy S, Emerit MB, Bolanos F, Schechter L. The central 5-HT1A receptors: pharmacological, biochemical, functional, and regulatory properties. Ann N Y Acad Sci 1990, 600(discussion):129-131.
-
(1990)
Ann N Y Acad Sci
, vol.600
, pp. 129-131
-
-
Hamon, M.1
Gozlan, H.2
El Mestikawy, S.3
Emerit, M.B.4
Bolanos, F.5
Schechter, L.6
-
16
-
-
0033827305
-
Central 5-HT(1A) receptors: regional distribution and functional characteristics.
-
Lanfumey L, Hamon M. Central 5-HT(1A) receptors: regional distribution and functional characteristics. Nucl Med Biol 2000, 27:429-435.
-
(2000)
Nucl Med Biol
, vol.27
, pp. 429-435
-
-
Lanfumey, L.1
Hamon, M.2
-
17
-
-
0035728258
-
Multiplicity of mechanisms of serotonin receptor signal transduction.
-
Raymond JR, Mukhin YV, Gelasco A, Turner J, Collinsworth G, Gettys TW, Grewal JS, Garnovskaya MN. Multiplicity of mechanisms of serotonin receptor signal transduction. Pharmacol Ther 2001, 92: 179-212.
-
(2001)
Pharmacol Ther
, vol.92
, pp. 179-212
-
-
Raymond, J.R.1
Mukhin, Y.V.2
Gelasco, A.3
Turner, J.4
Collinsworth, G.5
Gettys, T.W.6
Grewal, J.S.7
Garnovskaya, M.N.8
-
18
-
-
0025357878
-
Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron.
-
Penington NJ, Kelly JS. Serotonin receptor activation reduces calcium current in an acutely dissociated adult central neuron. Neuron 1990, 4:751-758.
-
(1990)
Neuron
, vol.4
, pp. 751-758
-
-
Penington, N.J.1
Kelly, J.S.2
-
19
-
-
33846903638
-
ERK2: a logical AND gate critical for drug-induced plasticity?
-
Girault JA, Valjent E, Caboche J, Herve D. ERK2: a logical AND gate critical for drug-induced plasticity? Curr Opin Pharmacol 2007, 7:77-85.
-
(2007)
Curr Opin Pharmacol
, vol.7
, pp. 77-85
-
-
Girault, J.A.1
Valjent, E.2
Caboche, J.3
Herve, D.4
-
20
-
-
0037019834
-
5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain.
-
Chen JY, Shen CP, Meller E. 5-HT1A receptor-mediated regulation of mitogen-activated protein kinase phosphorylation in rat brain. Eur J Pharmacol 2002, 452:155-162.
-
(2002)
Eur J Pharmacol
, vol.452
, pp. 155-162
-
-
Chen, J.Y.1
Shen, C.P.2
Meller, E.3
-
21
-
-
15044341121
-
Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo.
-
Sullivan NR, Crane JW, Damjanoska KJ, Carrasco GA, D'Souza DN, Garcia F, Van de Kar LD. Tandospirone activates neuroendocrine and ERK (MAP kinase) signaling pathways specifically through 5-HT1A receptor mechanisms in vivo. Naunyn Schmiedebergs Arch Pharmacol 2005, 371:18-26.
-
(2005)
Naunyn Schmiedebergs Arch Pharmacol
, vol.371
, pp. 18-26
-
-
Sullivan, N.R.1
Crane, J.W.2
Damjanoska, K.J.3
Carrasco, G.A.4
D'Souza, D.N.5
Garcia, F.6
Van de Kar, L.D.7
-
22
-
-
18844369809
-
5-HT receptors couple to activation of Akt, but not extracellular-regulated kinase (ERK), in cultured hippocampal neurons.
-
Cowen DS, Johnson-Farley NN, Travkina T. 5-HT receptors couple to activation of Akt, but not extracellular-regulated kinase (ERK), in cultured hippocampal neurons. J Neurochem 2005, 93:910-917.
-
(2005)
J Neurochem
, vol.93
, pp. 910-917
-
-
Cowen, D.S.1
Johnson-Farley, N.N.2
Travkina, T.3
-
23
-
-
7644226766
-
5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors.
-
Cloez-Tayarani I, Kayyali US, Fanburg BL, Cavaillon JM. 5-HT activates ERK MAP kinase in cultured-human peripheral blood mononuclear cells via 5-HT1A receptors. Life Sci 2004, 76:429-443.
-
(2004)
Life Sci
, vol.76
, pp. 429-443
-
-
Cloez-Tayarani, I.1
Kayyali, U.S.2
Fanburg, B.L.3
Cavaillon, J.M.4
-
24
-
-
29144456791
-
Roles of extracellular signal-regulated kinase and Akt signaling in coordinating nuclear transcription factor-κB-dependent cell survival after serotonin 1A receptor activation.
-
Hsiung SC, Tamir H, Franke TF, Liu KP. Roles of extracellular signal-regulated kinase and Akt signaling in coordinating nuclear transcription factor-κB-dependent cell survival after serotonin 1A receptor activation. J Neurochem 2005, 95:1653-1666.
-
(2005)
J Neurochem
, vol.95
, pp. 1653-1666
-
-
Hsiung, S.C.1
Tamir, H.2
Franke, T.F.3
Liu, K.P.4
-
25
-
-
33847067897
-
Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts.
-
Turner JH, Garnovskaya MN, Raymond JR. Serotonin 5-HT1A receptor stimulates c-Jun N-terminal kinase and induces apoptosis in Chinese hamster ovary fibroblasts. Biochim Biophys Acta 2007, 1773:391-399.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 391-399
-
-
Turner, J.H.1
Garnovskaya, M.N.2
Raymond, J.R.3
-
26
-
-
33845887518
-
Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor.
-
Turner JH, Garnovskaya MN, Coaxum SD, Vlasova TM, Yakutovich M, Lefler DM, Raymond JR. Ca2+-calmodulin and janus kinase 2 are required for activation of sodium-proton exchange by the Gi-coupled 5-hydroxytryptamine 1a receptor. J Pharmacol Exp Ther 2007, 320:314-322.
-
(2007)
J Pharmacol Exp Ther
, vol.320
, pp. 314-322
-
-
Turner, J.H.1
Garnovskaya, M.N.2
Coaxum, S.D.3
Vlasova, T.M.4
Yakutovich, M.5
Lefler, D.M.6
Raymond, J.R.7
-
27
-
-
20444398445
-
Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism.
-
Yuen EY, Jiang Q, Chen P, Gu Z, Feng J, Yan Z. Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism. J Neurosci 2005, 25:5488-5501.
-
(2005)
J Neurosci
, vol.25
, pp. 5488-5501
-
-
Yuen, E.Y.1
Jiang, Q.2
Chen, P.3
Gu, Z.4
Feng, J.5
Yan, Z.6
-
28
-
-
77249132263
-
Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors.
-
Zhang J, Huang XY, Ye ML, Luo CX, Wu HY, Hu Y, Zhou QG, Wu DL, Zhu LJ, Zhu DY. Neuronal nitric oxide synthase alteration accounts for the role of 5-HT1A receptor in modulating anxiety-related behaviors. J Neurosci 2010, 30:2433-2441.
-
(2010)
J Neurosci
, vol.30
, pp. 2433-2441
-
-
Zhang, J.1
Huang, X.Y.2
Ye, M.L.3
Luo, C.X.4
Wu, H.Y.5
Hu, Y.6
Zhou, Q.G.7
Wu, D.L.8
Zhu, L.J.9
Zhu, D.Y.10
-
29
-
-
77954645113
-
RGS inhibition at G(α)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.
-
Talbot JN, Jutkiewicz EM, Graves SM, Clemans CF, Nicol MR, Mortensen RM, Huang X, Neubig RR, Traynor JR. RGS inhibition at G(α)i2 selectively potentiates 5-HT1A-mediated antidepressant effects. Proc Natl Acad Sci U S A 2010, 107:11086-11091.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 11086-11091
-
-
Talbot, J.N.1
Jutkiewicz, E.M.2
Graves, S.M.3
Clemans, C.F.4
Nicol, M.R.5
Mortensen, R.M.6
Huang, X.7
Neubig, R.R.8
Traynor, J.R.9
-
30
-
-
33747593745
-
Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain.
-
Mannoury la Cour C, El Mestikawy S, Hanoun N, Hamon M, Lanfumey L. Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain. Mol Pharmacol 2006, 70:1013-1021.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1013-1021
-
-
Mannoury la Cour, C.1
El Mestikawy, S.2
Hanoun, N.3
Hamon, M.4
Lanfumey, L.5
-
31
-
-
67650222044
-
Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist.
-
Newman-Tancredi A, Martel JC, Assie MB, Buritova J, Lauressergues E, Cosi C, Heusler P, Bruins Slot L, Colpaert FC, Vacher B, et al. Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist. Br J Pharmacol 2009, 156:338-353.
-
(2009)
Br J Pharmacol
, vol.156
, pp. 338-353
-
-
Newman-Tancredi, A.1
Martel, J.C.2
Assie, M.B.3
Buritova, J.4
Lauressergues, E.5
Cosi, C.6
Heusler, P.7
Bruins Slot, L.8
Colpaert, F.C.9
Vacher, B.10
-
32
-
-
53149111135
-
Molecular biology of 5-HT receptors.
-
Hannon J, Hoyer D. Molecular biology of 5-HT receptors. Behav Brain Res 2008, 195:198-213.
-
(2008)
Behav Brain Res
, vol.195
, pp. 198-213
-
-
Hannon, J.1
Hoyer, D.2
-
33
-
-
0036024243
-
Differential coupling of 5-HT(1) receptors to G proteins of the G(i) family.
-
Lin SL, Setya S, Johnson-Farley NN, Cowen DS. Differential coupling of 5-HT(1) receptors to G proteins of the G(i) family. Br J Pharmacol 2002, 136:1072-1078.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 1072-1078
-
-
Lin, S.L.1
Setya, S.2
Johnson-Farley, N.N.3
Cowen, D.S.4
-
34
-
-
0037363664
-
h5-HT(1B) receptor-mediated constitutive Gαi3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT.
-
Newman-Tancredi A, Cussac D, Marini L, Touzard M, Millan MJ. h5-HT(1B) receptor-mediated constitutive Gαi3-protein activation in stably transfected Chinese hamster ovary cells: an antibody capture assay reveals protean efficacy of 5-HT. Br J Pharmacol 2003, 138:1077-1084.
-
(2003)
Br J Pharmacol
, vol.138
, pp. 1077-1084
-
-
Newman-Tancredi, A.1
Cussac, D.2
Marini, L.3
Touzard, M.4
Millan, M.J.5
-
35
-
-
0031565119
-
Adenovirus-mediated expression of 5-HT1B receptors in cardiac ventricle myocytes; coupling to inwardly rectifying K+ channels.
-
Ghavami A, Baruscotti M, Robinson RB, Hen R. Adenovirus-mediated expression of 5-HT1B receptors in cardiac ventricle myocytes; coupling to inwardly rectifying K+ channels. Eur J Pharmacol 1997, 340: 259-266.
-
(1997)
Eur J Pharmacol
, vol.340
, pp. 259-266
-
-
Ghavami, A.1
Baruscotti, M.2
Robinson, R.B.3
Hen, R.4
-
36
-
-
0031674609
-
Activation of recombinant h 5-HT1B and h 5-HT1D receptors stably expressed in C6 glioma cells produces increases in Ca2+-dependent K+ current.
-
Le Grand B, Panissie A, Pauwels PJ, John GW. Activation of recombinant h 5-HT1B and h 5-HT1D receptors stably expressed in C6 glioma cells produces increases in Ca2+-dependent K+ current. Naunyn Schmiedebergs Arch Pharmacol 1998, 358:608-615.
-
(1998)
Naunyn Schmiedebergs Arch Pharmacol
, vol.358
, pp. 608-615
-
-
Le Grand, B.1
Panissie, A.2
Pauwels, P.J.3
John, G.W.4
-
37
-
-
0036015179
-
Involvement of 5-HT1B and 5-HT1D receptors in sumatriptan mediated vasocontractile response in rabbit common carotid artery.
-
Akin D, Gurdal H. Involvement of 5-HT1B and 5-HT1D receptors in sumatriptan mediated vasocontractile response in rabbit common carotid artery. Br J Pharmacol 2002, 136:177-182.
-
(2002)
Br J Pharmacol
, vol.136
, pp. 177-182
-
-
Akin, D.1
Gurdal, H.2
-
38
-
-
74549226468
-
Mechanisms involved in the regulation of bovine pulmonary vascular tone by the 5-HT1B receptor.
-
McKenzie C, Alapati VR, MacDonald A, Shaw AM. Mechanisms involved in the regulation of bovine pulmonary vascular tone by the 5-HT1B receptor. Br J Pharmacol 2010, 159:188-200.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 188-200
-
-
McKenzie, C.1
Alapati, V.R.2
MacDonald, A.3
Shaw, A.M.4
-
39
-
-
33750087837
-
5-HT1B receptor-mediated presynaptic inhibition at the calyx of Held of immature rats.
-
Mizutani H, Hori T, Takahashi T. 5-HT1B receptor-mediated presynaptic inhibition at the calyx of Held of immature rats. Eur J Neurosci 2006, 24:1946-1954.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 1946-1954
-
-
Mizutani, H.1
Hori, T.2
Takahashi, T.3
-
40
-
-
53849083055
-
Novel interactions between the 5-HT transporter, 5-HT1B receptors and ρ kinase in vivo and in pulmonary fibroblasts.
-
Mair KM, MacLean MR, Morecroft I, Dempsie Y, Palmer TM. Novel interactions between the 5-HT transporter, 5-HT1B receptors and ρ kinase in vivo and in pulmonary fibroblasts. Br J Pharmacol 2008, 155:606-616.
-
(2008)
Br J Pharmacol
, vol.155
, pp. 606-616
-
-
Mair, K.M.1
MacLean, M.R.2
Morecroft, I.3
Dempsie, Y.4
Palmer, T.M.5
-
41
-
-
73149113991
-
Regulation of serotonin 1B receptor by glycogen synthase kinase-3.
-
Chen L, Salinas GD, Li X. Regulation of serotonin 1B receptor by glycogen synthase kinase-3. Mol Pharmacol 2009, 76:1150-1161.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 1150-1161
-
-
Chen, L.1
Salinas, G.D.2
Li, X.3
-
42
-
-
0030052084
-
Pharmacology of cloned human 5-HT1D receptor-mediated functional responses in stably transfected rat C6-glial cell lines: further evidence differentiating human 5-HT1D and 5-HT1B receptors.
-
Pauwels PJ, Palmier C, Wurch T, Colpaert FC. Pharmacology of cloned human 5-HT1D receptor-mediated functional responses in stably transfected rat C6-glial cell lines: further evidence differentiating human 5-HT1D and 5-HT1B receptors. Naunyn Schmiedebergs Arch Pharmacol 1996, 353:144-156.
-
(1996)
Naunyn Schmiedebergs Arch Pharmacol
, vol.353
, pp. 144-156
-
-
Pauwels, P.J.1
Palmier, C.2
Wurch, T.3
Colpaert, F.C.4
-
43
-
-
79551689024
-
Acute treatment of migraine with the selective 5-HT1F receptor agonist lasmiditan-a randomised proof-of-concept trial.
-
Ferrari MD, Farkkila M, Reuter U, Pilgrim A, Davis C, Krauss M, Diener HC. Acute treatment of migraine with the selective 5-HT1F receptor agonist lasmiditan-a randomised proof-of-concept trial. Cephalalgia 2010, 30:1170-1178.
-
(2010)
Cephalalgia
, vol.30
, pp. 1170-1178
-
-
Ferrari, M.D.1
Farkkila, M.2
Reuter, U.3
Pilgrim, A.4
Davis, C.5
Krauss, M.6
Diener, H.C.7
-
44
-
-
0021248714
-
Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex.
-
Conn PJ, Sanders-Bush E. Selective 5HT-2 antagonists inhibit serotonin stimulated phosphatidylinositol metabolism in cerebral cortex. Neuropharmacology 1984, 23:993-996.
-
(1984)
Neuropharmacology
, vol.23
, pp. 993-996
-
-
Conn, P.J.1
Sanders-Bush, E.2
-
45
-
-
0031200926
-
Stimulation of 5-HT2A receptors on astrocytes in primary culture opens voltage-independent Ca2+ channels.
-
Hagberg GB, Blomstrand F, Nilsson M, Tamir H, Hansson E. Stimulation of 5-HT2A receptors on astrocytes in primary culture opens voltage-independent Ca2+ channels. Neurochem Int 1998, 32:153-162.
-
(1998)
Neurochem Int
, vol.32
, pp. 153-162
-
-
Hagberg, G.B.1
Blomstrand, F.2
Nilsson, M.3
Tamir, H.4
Hansson, E.5
-
46
-
-
0042731683
-
A complex signaling cascade links the serotonin2A receptor to phospholipase A2 activation: the involvement of MAP kinases.
-
Kurrasch-Orbaugh DM, Parrish JC, Watts VJ, Nichols DE. A complex signaling cascade links the serotonin2A receptor to phospholipase A2 activation: the involvement of MAP kinases. J Neurochem 2003, 86:980-991.
-
(2003)
J Neurochem
, vol.86
, pp. 980-991
-
-
Kurrasch-Orbaugh, D.M.1
Parrish, J.C.2
Watts, V.J.3
Nichols, D.E.4
-
47
-
-
0036086484
-
Stimulation of 5-HT(2) receptors in prefrontal pyramidal neurons inhibits Ca(v)1.2 L type Ca(2+) currents via a PLCβ/IP3/calcineurin signaling cascade.
-
Day M, Olson PA, Platzer J, Striessnig J, Surmeier DJ. Stimulation of 5-HT(2) receptors in prefrontal pyramidal neurons inhibits Ca(v)1.2 L type Ca(2+) currents via a PLCβ/IP3/calcineurin signaling cascade. J Neurophysiol 2002, 87:2490-2504.
-
(2002)
J Neurophysiol
, vol.87
, pp. 2490-2504
-
-
Day, M.1
Olson, P.A.2
Platzer, J.3
Striessnig, J.4
Surmeier, D.J.5
-
48
-
-
0037104778
-
Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism.
-
Carr DB, Cooper DC, Ulrich SL, Spruston N, Surmeier DJ. Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism. J Neurosci 2002, 22:6846-6855.
-
(2002)
J Neurosci
, vol.22
, pp. 6846-6855
-
-
Carr, D.B.1
Cooper, D.C.2
Ulrich, S.L.3
Spruston, N.4
Surmeier, D.J.5
-
49
-
-
0036758605
-
Activation of presynaptic 5-hydroxytryptamine 2A receptors facilitates excitatory synaptic transmission via protein kinase C in the dorsolateral septal nucleus.
-
Hasuo H, Matsuoka T, Akasu T. Activation of presynaptic 5-hydroxytryptamine 2A receptors facilitates excitatory synaptic transmission via protein kinase C in the dorsolateral septal nucleus. J Neurosci 2002, 22:7509-7517.
-
(2002)
J Neurosci
, vol.22
, pp. 7509-7517
-
-
Hasuo, H.1
Matsuoka, T.2
Akasu, T.3
-
50
-
-
77957742904
-
Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ss-arrestin2/Src/Akt signaling complex in vivo.
-
Schmid CL, Bohn LM. Serotonin, but not N-methyltryptamines, activates the serotonin 2A receptor via a ss-arrestin2/Src/Akt signaling complex in vivo. J Neurosci 2010, 30:13513-13524.
-
(2010)
J Neurosci
, vol.30
, pp. 13513-13524
-
-
Schmid, C.L.1
Bohn, L.M.2
-
51
-
-
73349108833
-
Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling.
-
Jones KA, Srivastava DP, Allen JA, Strachan RT, Roth BL, Penzes P. Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling. Proc Natl Acad Sci U S A 2009, 106:19575-19580.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19575-19580
-
-
Jones, K.A.1
Srivastava, D.P.2
Allen, J.A.3
Strachan, R.T.4
Roth, B.L.5
Penzes, P.6
-
52
-
-
66749118877
-
PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors.
-
Abbas AI, Yadav PN, Yao WD, Arbuckle MI, Grant SG, Caron MG, Roth BL. PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. J Neurosci 2009, 29:7124-7136.
-
(2009)
J Neurosci
, vol.29
, pp. 7124-7136
-
-
Abbas, A.I.1
Yadav, P.N.2
Yao, W.D.3
Arbuckle, M.I.4
Grant, S.G.5
Caron, M.G.6
Roth, B.L.7
-
53
-
-
50049120656
-
c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta.
-
Lu R, Alioua A, Kumar Y, Kundu P, Eghbali M, Weisstaub NV, Gingrich JA, Stefani E, Toro L. c-Src tyrosine kinase, a critical component for 5-HT2A receptor-mediated contraction in rat aorta. J Physiol 2008, 586:3855-3869.
-
(2008)
J Physiol
, vol.586
, pp. 3855-3869
-
-
Lu, R.1
Alioua, A.2
Kumar, Y.3
Kundu, P.4
Eghbali, M.5
Weisstaub, N.V.6
Gingrich, J.A.7
Stefani, E.8
Toro, L.9
-
54
-
-
0036827963
-
Activation of extracellular-regulated kinase by 5-hydroxytryptamine(2A) receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases.
-
Quinn JC, Johnson-Farley NN, Yoon J, Cowen DS. Activation of extracellular-regulated kinase by 5-hydroxytryptamine(2A) receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases. J Pharmacol Exp Ther 2002, 303:746-752.
-
(2002)
J Pharmacol Exp Ther
, vol.303
, pp. 746-752
-
-
Quinn, J.C.1
Johnson-Farley, N.N.2
Yoon, J.3
Cowen, D.S.4
-
55
-
-
65549102184
-
Ribosomal S6 kinase 2 directly phosphorylates the 5-hydroxytryptamine 2A (5-HT2A) serotonin receptor, thereby modulating 5-HT2A signaling.
-
Strachan RT, Sheffler DJ, Willard B, Kinter M, Kiselar JG, Roth BL. Ribosomal S6 kinase 2 directly phosphorylates the 5-hydroxytryptamine 2A (5-HT2A) serotonin receptor, thereby modulating 5-HT2A signaling. J Biol Chem 2009, 284:5557-5573.
-
(2009)
J Biol Chem
, vol.284
, pp. 5557-5573
-
-
Strachan, R.T.1
Sheffler, D.J.2
Willard, B.3
Kinter, M.4
Kiselar, J.G.5
Roth, B.L.6
-
56
-
-
33746328093
-
5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-α-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells.
-
Gooz M, Gooz P, Luttrell LM, Raymond JR. 5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-α-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells. J Biol Chem 2006, 281:21004-21012.
-
(2006)
J Biol Chem
, vol.281
, pp. 21004-21012
-
-
Gooz, M.1
Gooz, P.2
Luttrell, L.M.3
Raymond, J.R.4
-
57
-
-
77951978885
-
The 5-HT 2A serotonin receptor enhances cell viability, affects cell cycle progression and activates MEK-ERK1/2 and JAK2-STAT3 signalling pathways in human choriocarcinoma cell lines.
-
Oufkir T, Arseneault M, Sanderson JT, Vaillancourt C. The 5-HT 2A serotonin receptor enhances cell viability, affects cell cycle progression and activates MEK-ERK1/2 and JAK2-STAT3 signalling pathways in human choriocarcinoma cell lines. Placenta 2010, 31:439-447.
-
(2010)
Placenta
, vol.31
, pp. 439-447
-
-
Oufkir, T.1
Arseneault, M.2
Sanderson, J.T.3
Vaillancourt, C.4
-
58
-
-
0030902977
-
Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway.
-
Guillet-Deniau I, Burnol AF, Girard J. Identification and localization of a skeletal muscle secrotonin 5-HT2A receptor coupled to the Jak/STAT pathway. J Biol Chem 1997, 272:14825-14829.
-
(1997)
J Biol Chem
, vol.272
, pp. 14825-14829
-
-
Guillet-Deniau, I.1
Burnol, A.F.2
Girard, J.3
-
59
-
-
15444366204
-
Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin.
-
Banes AK, Shaw SM, Tawfik A, Patel BP, Ogbi S, Fulton D, Marrero MB. Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin. Am J Physiol Cell Physiol 2005, 288:C805-C812.
-
(2005)
Am J Physiol Cell Physiol
, vol.288
-
-
Banes, A.K.1
Shaw, S.M.2
Tawfik, A.3
Patel, B.P.4
Ogbi, S.5
Fulton, D.6
Marrero, M.B.7
-
60
-
-
77953783776
-
Activation of the JAK-STAT pathway by olanzapine is necessary for desensitization of serotonin2A receptor-stimulated phospholipase C signaling in rat frontal cortex but not serotonin2A receptor-stimulated hormone release.
-
Singh RK, Jia C, Garcia F, Carrasco GA, Battaglia G, Muma NA. Activation of the JAK-STAT pathway by olanzapine is necessary for desensitization of serotonin2A receptor-stimulated phospholipase C signaling in rat frontal cortex but not serotonin2A receptor-stimulated hormone release. J Psychopharmacol 2010, 24:1079-1088.
-
(2010)
J Psychopharmacol
, vol.24
, pp. 1079-1088
-
-
Singh, R.K.1
Jia, C.2
Garcia, F.3
Carrasco, G.A.4
Battaglia, G.5
Muma, N.A.6
-
61
-
-
0035912862
-
Ablation of serotonin 5-HT(2B) receptors in mice leads to abnormal cardiac structure and function.
-
Nebigil CG, Hickel P, Messaddeq N, Vonesch JL, Douchet MP, Monassier L, Gyorgy K, Matz R, Andriantsitohaina R, Manivet P, et al. Ablation of serotonin 5-HT(2B) receptors in mice leads to abnormal cardiac structure and function. Circulation 2001, 103:2973-2979.
-
(2001)
Circulation
, vol.103
, pp. 2973-2979
-
-
Nebigil, C.G.1
Hickel, P.2
Messaddeq, N.3
Vonesch, J.L.4
Douchet, M.P.5
Monassier, L.6
Gyorgy, K.7
Matz, R.8
Andriantsitohaina, R.9
Manivet, P.10
-
62
-
-
0026706347
-
Cloning and functional characterization of the rat stomach fundus serotonin receptor.
-
Foguet M, Hoyer D, Pardo LA, Parekh A, Kluxen FW, Kalkman HO, Stuhmer W, Lubbert H. Cloning and functional characterization of the rat stomach fundus serotonin receptor. EMBO J 1992, 11:3481-3487.
-
(1992)
EMBO J
, vol.11
, pp. 3481-3487
-
-
Foguet, M.1
Hoyer, D.2
Pardo, L.A.3
Parekh, A.4
Kluxen, F.W.5
Kalkman, H.O.6
Stuhmer, W.7
Lubbert, H.8
-
63
-
-
0027055699
-
Molecular cloning, functional expression, and pharmacological characterization of a novel serotonin receptor (5-hydroxytryptamine2F) from rat stomach fundus.
-
Kursar JD, Nelson DL, Wainscott DB, Cohen ML, Baez M. Molecular cloning, functional expression, and pharmacological characterization of a novel serotonin receptor (5-hydroxytryptamine2F) from rat stomach fundus. Mol Pharmacol 1992, 42:549-557.
-
(1992)
Mol Pharmacol
, vol.42
, pp. 549-557
-
-
Kursar, J.D.1
Nelson, D.L.2
Wainscott, D.B.3
Cohen, M.L.4
Baez, M.5
-
64
-
-
0034987347
-
Developmentally regulated serotonin 5-HT2B receptors.
-
Nebigil CG, Etienne N, Schaerlinger B, Hickel P, Launay JM, Maroteaux L. Developmentally regulated serotonin 5-HT2B receptors. Int J Dev Neurosci 2001, 19:365-372.
-
(2001)
Int J Dev Neurosci
, vol.19
, pp. 365-372
-
-
Nebigil, C.G.1
Etienne, N.2
Schaerlinger, B.3
Hickel, P.4
Launay, J.M.5
Maroteaux, L.6
-
65
-
-
0030955863
-
5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells.
-
Choi DS, Ward SJ, Messaddeq N, Launay JM, Maroteaux L. 5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells. Development 1997, 124:1745-1755.
-
(1997)
Development
, vol.124
, pp. 1745-1755
-
-
Choi, D.S.1
Ward, S.J.2
Messaddeq, N.3
Launay, J.M.4
Maroteaux, L.5
-
66
-
-
0042934294
-
Functional consequence of serotonin/5-HT2B receptor signaling in heart: role of mitochondria in transition between hypertrophy and heart failure?
-
Nebigil CG, Maroteaux L. Functional consequence of serotonin/5-HT2B receptor signaling in heart: role of mitochondria in transition between hypertrophy and heart failure? Circulation 2003, 108:902-908.
-
(2003)
Circulation
, vol.108
, pp. 902-908
-
-
Nebigil, C.G.1
Maroteaux, L.2
-
67
-
-
0032504230
-
Cross-talk between 5-hydroxytryptamine receptors in a serotonergic cell line. Involvement of arachidonic acid metabolism.
-
Tournois C, Mutel V, Manivet P, Launay JM, Kellermann O. Cross-talk between 5-hydroxytryptamine receptors in a serotonergic cell line. Involvement of arachidonic acid metabolism. J Biol Chem 1998, 273:17498-17503.
-
(1998)
J Biol Chem
, vol.273
, pp. 17498-17503
-
-
Tournois, C.1
Mutel, V.2
Manivet, P.3
Launay, J.M.4
Kellermann, O.5
-
68
-
-
0034737423
-
PDZ-dependent activation of nitric-oxide synthases by the serotonin 2B receptor.
-
Manivet P, Mouillet-Richard S, Callebert J, Nebigil CG, Maroteaux L, Hosoda S, Kellermann O, Launay JM. PDZ-dependent activation of nitric-oxide synthases by the serotonin 2B receptor. J Biol Chem 2000, 275:9324-9331.
-
(2000)
J Biol Chem
, vol.275
, pp. 9324-9331
-
-
Manivet, P.1
Mouillet-Richard, S.2
Callebert, J.3
Nebigil, C.G.4
Maroteaux, L.5
Hosoda, S.6
Kellermann, O.7
Launay, J.M.8
-
69
-
-
0029665354
-
5-HT2B receptor signaling in the rat stomach fundus: dependence on calcium influx, calcium release and protein kinase C.
-
Cox DA, Cohen ML. 5-HT2B receptor signaling in the rat stomach fundus: dependence on calcium influx, calcium release and protein kinase C. Behav Brain Res 1996, 73:289-292.
-
(1996)
Behav Brain Res
, vol.73
, pp. 289-292
-
-
Cox, D.A.1
Cohen, M.L.2
-
70
-
-
0033624903
-
5-Hydroxytryptamine2B receptors stimulate Ca2+ increases in cultured astrocytes from three different brain regions.
-
Sanden N, Thorlin T, Blomstrand F, Persson PA, Hansson E. 5-Hydroxytryptamine2B receptors stimulate Ca2+ increases in cultured astrocytes from three different brain regions. Neurochem Int 2000, 36:427-434.
-
(2000)
Neurochem Int
, vol.36
, pp. 427-434
-
-
Sanden, N.1
Thorlin, T.2
Blomstrand, F.3
Persson, P.A.4
Hansson, E.5
-
71
-
-
77949311128
-
Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo.
-
Tharayil VS, Wouters MM, Stanich JE, Roeder JL, Lei S, Beyder A, Gomez-Pinilla PJ, Gershon MD, Maroteaux L, Gibbons SJ, et al. Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo. Neurogastroenterol Motil 2010, 22:e109-e410.
-
(2010)
Neurogastroenterol Motil
, vol.22
-
-
Tharayil, V.S.1
Wouters, M.M.2
Stanich, J.E.3
Roeder, J.L.4
Lei, S.5
Beyder, A.6
Gomez-Pinilla, P.J.7
Gershon, M.D.8
Maroteaux, L.9
Gibbons, S.J.10
-
72
-
-
69249118194
-
Protein kinase C{γ} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B.
-
Wouters MM, Roeder JL, Tharayil VS, Stanich JE, Strege PR, Lei S, Bardsley MR, Ordog T, Gibbons SJ, Farrugia G. Protein kinase C{γ} mediates regulation of proliferation by the serotonin 5-hydroxytryptamine receptor 2B. J Biol Chem 2009, 284:21177-21184.
-
(2009)
J Biol Chem
, vol.284
, pp. 21177-21184
-
-
Wouters, M.M.1
Roeder, J.L.2
Tharayil, V.S.3
Stanich, J.E.4
Strege, P.R.5
Lei, S.6
Bardsley, M.R.7
Ordog, T.8
Gibbons, S.J.9
Farrugia, G.10
-
73
-
-
77950614403
-
Serotonin promotes tumor growth in human hepatocellular cancer.
-
Soll C, Jang JH, Riener MO, Moritz W, Wild PJ, Graf R, Clavien PA. Serotonin promotes tumor growth in human hepatocellular cancer. Hepatology 2010, 51:1244-1254.
-
(2010)
Hepatology
, vol.51
, pp. 1244-1254
-
-
Soll, C.1
Jang, J.H.2
Riener, M.O.3
Moritz, W.4
Wild, P.J.5
Graf, R.6
Clavien, P.A.7
-
74
-
-
65549134709
-
Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation.
-
Asada M, Ebihara S, Yamanda S, Niu K, Okazaki T, Sora I, Arai H. Depletion of serotonin and selective inhibition of 2B receptor suppressed tumor angiogenesis by inhibiting endothelial nitric oxide synthase and extracellular signal-regulated kinase 1/2 phosphorylation. Neoplasia 2009, 11:408-417.
-
(2009)
Neoplasia
, vol.11
, pp. 408-417
-
-
Asada, M.1
Ebihara, S.2
Yamanda, S.3
Niu, K.4
Okazaki, T.5
Sora, I.6
Arai, H.7
-
75
-
-
0034646263
-
5-hydroxytryptamine 2B receptor regulates cell-cycle progression: cross-talk with tyrosine kinase pathways.
-
Nebigil CG, Launay JM, Hickel P, Tournois C, Maroteaux L. 5-hydroxytryptamine 2B receptor regulates cell-cycle progression: cross-talk with tyrosine kinase pathways. Proc Natl Acad Sci U S A 2000, 97:2591-2596.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2591-2596
-
-
Nebigil, C.G.1
Launay, J.M.2
Hickel, P.3
Tournois, C.4
Maroteaux, L.5
-
76
-
-
34147095275
-
Functions of serotonin in hypoxic pulmonary vascular remodeling.
-
Esteve JM, Launay JM, Kellermann O, Maroteaux L. Functions of serotonin in hypoxic pulmonary vascular remodeling. Cell Biochem Biophys 2007, 47:33-44.
-
(2007)
Cell Biochem Biophys
, vol.47
, pp. 33-44
-
-
Esteve, J.M.1
Launay, J.M.2
Kellermann, O.3
Maroteaux, L.4
-
77
-
-
68049119944
-
Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation.
-
Li B, Zhang S, Li M, Hertz L, Peng L. Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation. Psychopharmacology (Berl) 2009, 207:1-12.
-
(2009)
Psychopharmacology (Berl)
, vol.207
, pp. 1-12
-
-
Li, B.1
Zhang, S.2
Li, M.3
Hertz, L.4
Peng, L.5
-
78
-
-
33947596291
-
Control of bioamine metabolism by 5-HT2B and α 1D autoreceptors through reactive oxygen species and tumor necrosis factor-α signaling in neuronal cells.
-
Schneider B, Pietri M, Mouillet-Richard S, Ermonval M, Mutel V, Launay JM, Kellermann O. Control of bioamine metabolism by 5-HT2B and α 1D autoreceptors through reactive oxygen species and tumor necrosis factor-α signaling in neuronal cells. Ann N Y Acad Sci 2006, 1091:123-141.
-
(2006)
Ann N Y Acad Sci
, vol.1091
, pp. 123-141
-
-
Schneider, B.1
Pietri, M.2
Mouillet-Richard, S.3
Ermonval, M.4
Mutel, V.5
Launay, J.M.6
Kellermann, O.7
-
79
-
-
33748648565
-
Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells.
-
Launay JM, Schneider B, Loric S, Da Prada M, Kellermann O. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB J 2006, 20:1843-1854.
-
(2006)
FASEB J
, vol.20
, pp. 1843-1854
-
-
Launay, J.M.1
Schneider, B.2
Loric, S.3
Da Prada, M.4
Kellermann, O.5
-
80
-
-
33749437283
-
Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-κB in cardiomyocytes.
-
Liang YJ, Lai LP, Wang BW, Juang SJ, Chang CM, Leu JG, Shyu KG. Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-κB in cardiomyocytes. Cardiovasc Res 2006, 72:303-312.
-
(2006)
Cardiovasc Res
, vol.72
, pp. 303-312
-
-
Liang, Y.J.1
Lai, L.P.2
Wang, B.W.3
Juang, S.J.4
Chang, C.M.5
Leu, J.G.6
Shyu, K.G.7
-
81
-
-
59649114815
-
Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
-
Jaffre F, Bonnin P, Callebert J, Debbabi H, Setola V, Doly S, Monassier L, Mettauer B, Blaxall BC, Launay JM, et al. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy. Circ Res 2009, 104:113-123.
-
(2009)
Circ Res
, vol.104
, pp. 113-123
-
-
Jaffre, F.1
Bonnin, P.2
Callebert, J.3
Debbabi, H.4
Setola, V.5
Doly, S.6
Monassier, L.7
Mettauer, B.8
Blaxall, B.C.9
Launay, J.M.10
-
82
-
-
69549126263
-
Amyloid β-derived neuroplasticity in bone marrow-derived mesenchymal stem cells is mediated by NPY and 5-HT2B receptors via ERK1/2 signalling pathways.
-
Jin HK, Bae JS, Furuya S, Carter JE. Amyloid β-derived neuroplasticity in bone marrow-derived mesenchymal stem cells is mediated by NPY and 5-HT2B receptors via ERK1/2 signalling pathways. Cell Prolif 2009, 42:571-586.
-
(2009)
Cell Prolif
, vol.42
, pp. 571-586
-
-
Jin, H.K.1
Bae, J.S.2
Furuya, S.3
Carter, J.E.4
-
83
-
-
0023708425
-
Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus.
-
Sanders-Bush E, Breeding M. Putative selective 5-HT-2 antagonists block serotonin 5-HT-1c receptors in the choroid plexus. J Pharmacol Exp Ther 1988, 247:169-173.
-
(1988)
J Pharmacol Exp Ther
, vol.247
, pp. 169-173
-
-
Sanders-Bush, E.1
Breeding, M.2
-
84
-
-
27744445373
-
Serotonin 5-ht2c receptor agonists: potential for the treatment of obesity.
-
Miller KJ. Serotonin 5-ht2c receptor agonists: potential for the treatment of obesity. Mol Interv 2005, 5:282-291.
-
(2005)
Mol Interv
, vol.5
, pp. 282-291
-
-
Miller, K.J.1
-
85
-
-
78649652034
-
New horizons for selective 5-HT2C receptor ligands in psychiatric/neurological disorders.
-
Rosenzweig-Lipson S. New horizons for selective 5-HT2C receptor ligands in psychiatric/neurological disorders. Neuropsychopharmacology 2011, 36:363-364.
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 363-364
-
-
Rosenzweig-Lipson, S.1
-
86
-
-
46149088211
-
RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function.
-
Werry TD, Loiacono R, Sexton PM, Christopoulos A. RNA editing of the serotonin 5HT2C receptor and its effects on cell signalling, pharmacology and brain function. Pharmacol Ther 2008, 119:7-23.
-
(2008)
Pharmacol Ther
, vol.119
, pp. 7-23
-
-
Werry, T.D.1
Loiacono, R.2
Sexton, P.M.3
Christopoulos, A.4
-
87
-
-
1442276297
-
Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells.
-
Speake T, Kibble JD, Brown PD. Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells. Am J Physiol Cell Physiol 2004, 286:C611-C620.
-
(2004)
Am J Physiol Cell Physiol
, vol.286
-
-
Speake, T.1
Kibble, J.D.2
Brown, P.D.3
-
88
-
-
34748903427
-
Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females.
-
Qiu J, Xue C, Bosch MA, Murphy JG, Fan W, Ronnekleiv OK, Kelly MJ. Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females. Mol Pharmacol 2007, 72:885-896.
-
(2007)
Mol Pharmacol
, vol.72
, pp. 885-896
-
-
Qiu, J.1
Xue, C.2
Bosch, M.A.3
Murphy, J.G.4
Fan, W.5
Ronnekleiv, O.K.6
Kelly, M.J.7
-
89
-
-
64849090472
-
Serotonin excites fast-spiking interneurons in the striatum.
-
Blomeley CP, Bracci E. Serotonin excites fast-spiking interneurons in the striatum. Eur J Neurosci 2009, 29:1604-1614.
-
(2009)
Eur J Neurosci
, vol.29
, pp. 1604-1614
-
-
Blomeley, C.P.1
Bracci, E.2
-
90
-
-
20744434986
-
Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2.
-
Werry TD, Gregory KJ, Sexton PM, Christopoulos A. Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2. J Neurochem 2005, 93:1603-1615.
-
(2005)
J Neurochem
, vol.93
, pp. 1603-1615
-
-
Werry, T.D.1
Gregory, K.J.2
Sexton, P.M.3
Christopoulos, A.4
-
91
-
-
77958130024
-
Constitutive activity of Serotonin2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants.
-
Labasque M, Meffre J, Carrat G, Becamel C, Bockaert J, Marin P. Constitutive activity of Serotonin2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants. Mol Pharmacol 2010, 78:818-826.
-
(2010)
Mol Pharmacol
, vol.78
, pp. 818-826
-
-
Labasque, M.1
Meffre, J.2
Carrat, G.3
Becamel, C.4
Bockaert, J.5
Marin, P.6
-
92
-
-
1642453638
-
RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoforms.
-
Marion S, Weiner DM, Caron MG. RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoforms. J Biol Chem 2004, 279:2945-2954.
-
(2004)
J Biol Chem
, vol.279
, pp. 2945-2954
-
-
Marion, S.1
Weiner, D.M.2
Caron, M.G.3
-
93
-
-
0024073762
-
5-HT3 receptors mediate rapid responses in cultured hippocampus and a clonal cell line.
-
Yakel JL, Jackson MB. 5-HT3 receptors mediate rapid responses in cultured hippocampus and a clonal cell line. Neuron 1988, 1:615-621.
-
(1988)
Neuron
, vol.1
, pp. 615-621
-
-
Yakel, J.L.1
Jackson, M.B.2
-
94
-
-
0036458391
-
Differential subcellular localization of the 5-HT3-As receptor subunit in the rat central nervous system.
-
Miquel MC, Emerit MB, Nosjean A, Simon A, Rumajogee P, Brisorgueil MJ, Doucet E, Hamon M, Verge D. Differential subcellular localization of the 5-HT3-As receptor subunit in the rat central nervous system. Eur J Neurosci 2002, 15:449-457.
-
(2002)
Eur J Neurosci
, vol.15
, pp. 449-457
-
-
Miquel, M.C.1
Emerit, M.B.2
Nosjean, A.3
Simon, A.4
Rumajogee, P.5
Brisorgueil, M.J.6
Doucet, E.7
Hamon, M.8
Verge, D.9
-
96
-
-
1642344952
-
A nitrergic secretomotor neurotransmitter in the chloride secretory response to serotonin.
-
King BN, Stoner MC, Haque SM, Kellum JM. A nitrergic secretomotor neurotransmitter in the chloride secretory response to serotonin. Dig Dis Sci 2004, 49:196-201.
-
(2004)
Dig Dis Sci
, vol.49
, pp. 196-201
-
-
King, B.N.1
Stoner, M.C.2
Haque, S.M.3
Kellum, J.M.4
-
97
-
-
0031025390
-
5-Hydroxytryptamine-facilitated release of substance P from rat spinal cord slices is mediated by nitric oxide and cyclic GMP.
-
Inoue A, Hashimoto T, Hide I, Nishio H, Nakata Y. 5-Hydroxytryptamine-facilitated release of substance P from rat spinal cord slices is mediated by nitric oxide and cyclic GMP. J Neurochem 1997, 68:128-133.
-
(1997)
J Neurochem
, vol.68
, pp. 128-133
-
-
Inoue, A.1
Hashimoto, T.2
Hide, I.3
Nishio, H.4
Nakata, Y.5
-
98
-
-
58049215463
-
The 5-HT3 receptor-the relationship between structure and function.
-
Barnes NM, Hales TG, Lummis SC, Peters JA. The 5-HT3 receptor-the relationship between structure and function. Neuropharmacology 2009, 56:273-284.
-
(2009)
Neuropharmacology
, vol.56
, pp. 273-284
-
-
Barnes, N.M.1
Hales, T.G.2
Lummis, S.C.3
Peters, J.A.4
-
99
-
-
78650661080
-
5-HT(3) receptors: role in disease and target of drugs.
-
Walstab J, Rappold G, Niesler B. 5-HT(3) receptors: role in disease and target of drugs. Pharmacol Ther 2010, 128:146-169.
-
(2010)
Pharmacol Ther
, vol.128
, pp. 146-169
-
-
Walstab, J.1
Rappold, G.2
Niesler, B.3
-
100
-
-
0033611396
-
The 5-HT3B subunit is a major determinant of serotonin-receptor function.
-
Davies PA, Pistis M, Hanna MC, Peters JA, Lambert JJ, Hales TG, Kirkness EF. The 5-HT3B subunit is a major determinant of serotonin-receptor function. Nature 1999, 397:359-363.
-
(1999)
Nature
, vol.397
, pp. 359-363
-
-
Davies, P.A.1
Pistis, M.2
Hanna, M.C.3
Peters, J.A.4
Lambert, J.J.5
Hales, T.G.6
Kirkness, E.F.7
-
101
-
-
0029002791
-
Phosphorylation controls conductance of 5-HT3 receptor ligand-gated ion channels.
-
Van Hooft JA, Vijverberg HP. Phosphorylation controls conductance of 5-HT3 receptor ligand-gated ion channels. Receptors Channels 1995, 3:7-12.
-
(1995)
Receptors Channels
, vol.3
, pp. 7-12
-
-
Van Hooft, J.A.1
Vijverberg, H.P.2
-
102
-
-
0036395239
-
Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins.
-
Boyd GW, Low P, Dunlop JI, Robertson LA, Vardy A, Lambert JJ, Peters JA, Connolly CN. Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: the role of oligomerization and chaperone proteins. Mol Cell Neurosci 2002, 21:38-50.
-
(2002)
Mol Cell Neurosci
, vol.21
, pp. 38-50
-
-
Boyd, G.W.1
Low, P.2
Dunlop, J.I.3
Robertson, L.A.4
Vardy, A.5
Lambert, J.J.6
Peters, J.A.7
Connolly, C.N.8
-
103
-
-
20444483701
-
Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3.
-
Cheng A, McDonald NA, Connolly CN. Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3. J Biol Chem 2005, 280:22502-22507.
-
(2005)
J Biol Chem
, vol.280
, pp. 22502-22507
-
-
Cheng, A.1
McDonald, N.A.2
Connolly, C.N.3
-
104
-
-
0037443123
-
Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels.
-
Boue-Grabot E, Barajas-Lopez C, Chakfe Y, Blais D, Belanger D, Emerit MB, Seguela P. Intracellular cross talk and physical interaction between two classes of neurotransmitter-gated channels. J Neurosci 2003, 23:1246-1253.
-
(2003)
J Neurosci
, vol.23
, pp. 1246-1253
-
-
Boue-Grabot, E.1
Barajas-Lopez, C.2
Chakfe, Y.3
Blais, D.4
Belanger, D.5
Emerit, M.B.6
Seguela, P.7
-
105
-
-
0036283377
-
Native and cloned 5-HT(3A)(S) receptors are anchored to F-actin in clonal cells and neurons.
-
Emerit MB, Doucet E, Darmon M, Hamon M. Native and cloned 5-HT(3A)(S) receptors are anchored to F-actin in clonal cells and neurons. Mol Cell Neurosci 2002, 20:110-124.
-
(2002)
Mol Cell Neurosci
, vol.20
, pp. 110-124
-
-
Emerit, M.B.1
Doucet, E.2
Darmon, M.3
Hamon, M.4
-
106
-
-
38849150236
-
Modulation of 5-HT3 receptor desensitization by the light chain of microtubule-associated protein 1B expressed in HEK 293 cells.
-
Sun H, Hu XQ, Emerit MB, Schoenebeck JC, Kimmel CE, Peoples RW, Miko A, Zhang L. Modulation of 5-HT3 receptor desensitization by the light chain of microtubule-associated protein 1B expressed in HEK 293 cells. J Physiol 2008, 586:751-762.
-
(2008)
J Physiol
, vol.586
, pp. 751-762
-
-
Sun, H.1
Hu, X.Q.2
Emerit, M.B.3
Schoenebeck, J.C.4
Kimmel, C.E.5
Peoples, R.W.6
Miko, A.7
Zhang, L.8
-
107
-
-
33748943679
-
Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation.
-
Bockaert J, Claeysen S, Becamel C, Dumuis A, Marin P. Neuronal 5-HT metabotropic receptors: fine-tuning of their structure, signaling, and roles in synaptic modulation. Cell Tissue Res 2006, 326:553-572.
-
(2006)
Cell Tissue Res
, vol.326
, pp. 553-572
-
-
Bockaert, J.1
Claeysen, S.2
Becamel, C.3
Dumuis, A.4
Marin, P.5
-
108
-
-
53449091766
-
5-HT(4) receptors: history, molecular pharmacology and brain functions.
-
Bockaert J, Claeysen S, Compan V, Dumuis A. 5-HT(4) receptors: history, molecular pharmacology and brain functions. Neuropharmacology 2008, 55:922-931.
-
(2008)
Neuropharmacology
, vol.55
, pp. 922-931
-
-
Bockaert, J.1
Claeysen, S.2
Compan, V.3
Dumuis, A.4
-
109
-
-
0037036372
-
5-Hydroxytryptamine 4(a) receptor is coupled to the Gα subunit of heterotrimeric G13 protein.
-
Ponimaskin EG, Profirovic J, Vaiskunaite R, Richter DW, Voyno-Yasenetskaya TA. 5-Hydroxytryptamine 4(a) receptor is coupled to the Gα subunit of heterotrimeric G13 protein. J Biol Chem 2002, 277:20812-20819.
-
(2002)
J Biol Chem
, vol.277
, pp. 20812-20819
-
-
Ponimaskin, E.G.1
Profirovic, J.2
Vaiskunaite, R.3
Richter, D.W.4
Voyno-Yasenetskaya, T.A.5
-
110
-
-
0036140947
-
Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Gαs- and Gαi/o-proteins.
-
Pindon A, van Hecke G, van Gompel P, Lesage AS, Leysen JE, Jurzak M. Differences in signal transduction of two 5-HT4 receptor splice variants: compound specificity and dual coupling with Gαs- and Gαi/o-proteins. Mol Pharmacol 2002, 61:85-96.
-
(2002)
Mol Pharmacol
, vol.61
, pp. 85-96
-
-
Pindon, A.1
van Hecke, G.2
van Gompel, P.3
Lesage, A.S.4
Leysen, J.E.5
Jurzak, M.6
-
111
-
-
35948953185
-
Regulation of apoptosis signal-regulating kinase 1 degradation by G α13.
-
Kutuzov MA, Andreeva AV, Voyno-Yasenetskaya TA. Regulation of apoptosis signal-regulating kinase 1 degradation by G α13. FASEB J 2007, 21:3727-3736.
-
(2007)
FASEB J
, vol.21
, pp. 3727-3736
-
-
Kutuzov, M.A.1
Andreeva, A.V.2
Voyno-Yasenetskaya, T.A.3
-
112
-
-
29444439666
-
Serotonin (5-HT) receptor subtypes mediate specific modes of 5-HT-induced signaling and regulation of neurosecretion in gonadotropin-releasing hormone neurons.
-
Wada K, Hu L, Mores N, Navarro CE, Fuda H, Krsmanovic LZ, Catt KJ. Serotonin (5-HT) receptor subtypes mediate specific modes of 5-HT-induced signaling and regulation of neurosecretion in gonadotropin-releasing hormone neurons. Mol Endocrinol 2006, 20:125-135.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 125-135
-
-
Wada, K.1
Hu, L.2
Mores, N.3
Navarro, C.E.4
Fuda, H.5
Krsmanovic, L.Z.6
Catt, K.J.7
-
113
-
-
79953677455
-
5-HT(4) receptors, a place in the sun: act two.
-
Bockaert J, Claeysen S, Compan V, Dumuis A. 5-HT(4) receptors, a place in the sun: act two. Curr Opin Pharmacol 2011, 11:87-93.
-
(2011)
Curr Opin Pharmacol
, vol.11
, pp. 87-93
-
-
Bockaert, J.1
Claeysen, S.2
Compan, V.3
Dumuis, A.4
-
114
-
-
34548026555
-
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux.
-
Mohler EG, Shacham S, Noiman S, Lezoualc'h F, Robert S, Gastineau M, Rutkowski J, Marantz Y, Dumuis A, Bockaert J, et al. VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux. Neuropharmacology 2007, 53:563-573.
-
(2007)
Neuropharmacology
, vol.53
, pp. 563-573
-
-
Mohler, E.G.1
Shacham, S.2
Noiman, S.3
Lezoualc'h, F.4
Robert, S.5
Gastineau, M.6
Rutkowski, J.7
Marantz, Y.8
Dumuis, A.9
Bockaert, J.10
-
115
-
-
49549091142
-
The promnesic effect of G-protein-coupled 5-HT4 receptors activation is mediated by a potentiation of learning-induced spine growth in the mouse hippocampus.
-
Restivo L, Roman F, Dumuis A, Bockaert J, Marchetti E, Ammassari-Teule M. The promnesic effect of G-protein-coupled 5-HT4 receptors activation is mediated by a potentiation of learning-induced spine growth in the mouse hippocampus. Neuropsychopharmacology 2008, 33:2427-2434.
-
(2008)
Neuropsychopharmacology
, vol.33
, pp. 2427-2434
-
-
Restivo, L.1
Roman, F.2
Dumuis, A.3
Bockaert, J.4
Marchetti, E.5
Ammassari-Teule, M.6
-
116
-
-
34248570473
-
5-HT4 receptor and Alzheimer's disease: the amyloid connection.
-
Lezoualc'h F. 5-HT4 receptor and Alzheimer's disease: the amyloid connection. Exp Neurol 2007, 205:325-329.
-
(2007)
Exp Neurol
, vol.205
, pp. 325-329
-
-
Lezoualc'h, F.1
-
117
-
-
0029047231
-
cAMP-dependent, long-lasting inhibition of a K+ current in mammalian neurons.
-
Ansanay H, Dumuis A, Sebben M, Bockaert J, Fagni L. cAMP-dependent, long-lasting inhibition of a K+ current in mammalian neurons. Proc Natl Acad Sci U S A 1995, 92:6635-6639.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 6635-6639
-
-
Ansanay, H.1
Dumuis, A.2
Sebben, M.3
Bockaert, J.4
Fagni, L.5
-
118
-
-
0037052728
-
The 5-HT(4) receptor-induced depolarization in rat hippocampal neurons is mediated by cAMP but is independent of I(h).
-
Chapin EM, Haj-Dahmane S, Torres G, Andrade R. The 5-HT(4) receptor-induced depolarization in rat hippocampal neurons is mediated by cAMP but is independent of I(h). Neurosci Lett 2002, 324:1-4.
-
(2002)
Neurosci Lett
, vol.324
, pp. 1-4
-
-
Chapin, E.M.1
Haj-Dahmane, S.2
Torres, G.3
Andrade, R.4
-
119
-
-
0026611585
-
The 5-HT4 receptor subtype inhibits K+ current in colliculi neurones via activation of a cyclic AMP-dependent protein kinase.
-
Fagni L, Dumuis A, Sebben M, Bockaert J. The 5-HT4 receptor subtype inhibits K+ current in colliculi neurones via activation of a cyclic AMP-dependent protein kinase. Br J Pharmacol 1992, 105:973-979.
-
(1992)
Br J Pharmacol
, vol.105
, pp. 973-979
-
-
Fagni, L.1
Dumuis, A.2
Sebben, M.3
Bockaert, J.4
-
120
-
-
33747172198
-
5-HT4 receptor activation induces long-lasting EPSP-spike potentiation in CA1 pyramidal neurons.
-
Mlinar B, Mascalchi S, Mannaioni G, Morini R, Corradetti R. 5-HT4 receptor activation induces long-lasting EPSP-spike potentiation in CA1 pyramidal neurons. Eur J Neurosci 2006, 24:719-731.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 719-731
-
-
Mlinar, B.1
Mascalchi, S.2
Mannaioni, G.3
Morini, R.4
Corradetti, R.5
-
121
-
-
0025923176
-
5-Hydroxytryptamine4-like receptors mediate the slow excitatory response to serotonin in the rat hippocampus.
-
Andrade R, Chaput Y. 5-Hydroxytryptamine4-like receptors mediate the slow excitatory response to serotonin in the rat hippocampus. J Pharmacol Exp Ther 1991, 257:930-937.
-
(1991)
J Pharmacol Exp Ther
, vol.257
, pp. 930-937
-
-
Andrade, R.1
Chaput, Y.2
-
122
-
-
0029661852
-
5-Hydroxy tryptamine4 receptors reduce afterhyperpolarization in hippocampus by inhibiting calcium-induced calcium release.
-
Torres GE, Arfken CL, Andrade R. 5-Hydroxy tryptamine4 receptors reduce afterhyperpolarization in hippocampus by inhibiting calcium-induced calcium release. Mol Pharmacol 1996, 50:1316-1322.
-
(1996)
Mol Pharmacol
, vol.50
, pp. 1316-1322
-
-
Torres, G.E.1
Arfken, C.L.2
Andrade, R.3
-
123
-
-
35348946325
-
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes.
-
Birkeland JA, Swift F, Tovsrud N, Enger U, Lunde PK, Qvigstad E, Levy FO, Sejersted OM, Sjaastad I. Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes. Am J Physiol Heart Circ Physiol 2007, 293:H2367-H2376.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
-
-
Birkeland, J.A.1
Swift, F.2
Tovsrud, N.3
Enger, U.4
Lunde, P.K.5
Qvigstad, E.6
Levy, F.O.7
Sejersted, O.M.8
Sjaastad, I.9
-
124
-
-
34250320534
-
5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or β-arrestin signaling.
-
Barthet G, Framery B, Gaven F, Pellissier L, Reiter E, Claeysen S, Bockaert J, Dumuis A. 5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or β-arrestin signaling. Mol Biol Cell 2007, 18:1979-1991.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 1979-1991
-
-
Barthet, G.1
Framery, B.2
Gaven, F.3
Pellissier, L.4
Reiter, E.5
Claeysen, S.6
Bockaert, J.7
Dumuis, A.8
-
125
-
-
33845665020
-
Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells.
-
Norum JH, Dawood H, Mattingly RR, Sandnes D, Levy FO. Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells. FEBS Lett 2007, 581:15-20.
-
(2007)
FEBS Lett
, vol.581
, pp. 15-20
-
-
Norum, J.H.1
Dawood, H.2
Mattingly, R.R.3
Sandnes, D.4
Levy, F.O.5
-
126
-
-
0037474246
-
Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a).
-
Norum JH, Hart K, Levy FO. Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a). J Biol Chem 2003, 278:3098-3104.
-
(2003)
J Biol Chem
, vol.278
, pp. 3098-3104
-
-
Norum, J.H.1
Hart, K.2
Levy, F.O.3
-
127
-
-
70349210074
-
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
-
Barthet G, Carrat G, Cassier E, Barker B, Gaven F, Pillot M, Framery B, Pellissier LP, Augier J, Kang DS, et al. Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling. EMBO J 2009, 28:2706-2718.
-
(2009)
EMBO J
, vol.28
, pp. 2706-2718
-
-
Barthet, G.1
Carrat, G.2
Cassier, E.3
Barker, B.4
Gaven, F.5
Pillot, M.6
Framery, B.7
Pellissier, L.P.8
Augier, J.9
Kang, D.S.10
-
128
-
-
17144397989
-
Serotonin inhibits Na+/H+ exchange activity via 5-HT4 receptors and activation of PKC α in human intestinal epithelial cells.
-
Gill RK, Saksena S, Tyagi S, Alrefai WA, Malakooti J, Sarwar Z, Turner JR, Ramaswamy K, Dudeja PK. Serotonin inhibits Na+/H+ exchange activity via 5-HT4 receptors and activation of PKC α in human intestinal epithelial cells. Gastroenterology 2005, 128:962-974.
-
(2005)
Gastroenterology
, vol.128
, pp. 962-974
-
-
Gill, R.K.1
Saksena, S.2
Tyagi, S.3
Alrefai, W.A.4
Malakooti, J.5
Sarwar, Z.6
Turner, J.R.7
Ramaswamy, K.8
Dudeja, P.K.9
-
129
-
-
68549123001
-
5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice.
-
Liu MT, Kuan YH, Wang J, Hen R, Gershon MD. 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice. J Neurosci 2009, 29:9683-9699.
-
(2009)
J Neurosci
, vol.29
, pp. 9683-9699
-
-
Liu, M.T.1
Kuan, Y.H.2
Wang, J.3
Hen, R.4
Gershon, M.D.5
-
130
-
-
0027339423
-
Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization.
-
Matthes H, Boschert U, Amlaiky N, Grailhe R, Plassat JL, Muscatelli F, Mattei MG, Hen R. Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors define a new family of serotonin receptors: cloning, functional expression, and chromosomal localization. Mol Pharmacol 1993, 43:313-319.
-
(1993)
Mol Pharmacol
, vol.43
, pp. 313-319
-
-
Matthes, H.1
Boschert, U.2
Amlaiky, N.3
Grailhe, R.4
Plassat, J.L.5
Muscatelli, F.6
Mattei, M.G.7
Hen, R.8
-
131
-
-
0029658014
-
The 5HT5A serotonin receptor is expressed predominantly by astrocytes in which it inhibits cAMP accumulation: a mechanism for neuronal suppression of reactive astrocytes.
-
Carson MJ, Thomas EA, Danielson PE, Sutcliffe JG. The 5HT5A serotonin receptor is expressed predominantly by astrocytes in which it inhibits cAMP accumulation: a mechanism for neuronal suppression of reactive astrocytes. Glia 1996, 17:317-326.
-
(1996)
Glia
, vol.17
, pp. 317-326
-
-
Carson, M.J.1
Thomas, E.A.2
Danielson, P.E.3
Sutcliffe, J.G.4
-
132
-
-
0035957719
-
Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution.
-
Grailhe R, Grabtree GW, Hen R. Human 5-HT(5) receptors: the 5-HT(5A) receptor is functional but the 5-HT(5B) receptor was lost during mammalian evolution. Eur J Pharmacol 2001, 418:157-167.
-
(2001)
Eur J Pharmacol
, vol.418
, pp. 157-167
-
-
Grailhe, R.1
Grabtree, G.W.2
Hen, R.3
-
133
-
-
0037269430
-
Recombinant human serotonin 5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways.
-
Noda M, Yasuda S, Okada M, Higashida H, Shimada A, Iwata N, Ozaki N, Nishikawa K, Shirasawa S, Uchida M, et al. Recombinant human serotonin 5A receptors stably expressed in C6 glioma cells couple to multiple signal transduction pathways. J Neurochem 2003, 84:222-232.
-
(2003)
J Neurochem
, vol.84
, pp. 222-232
-
-
Noda, M.1
Yasuda, S.2
Okada, M.3
Higashida, H.4
Shimada, A.5
Iwata, N.6
Ozaki, N.7
Nishikawa, K.8
Shirasawa, S.9
Uchida, M.10
-
134
-
-
0032553120
-
The human 5-ht5A receptor couples to Gi/Go proteins and inhibits adenylate cyclase in HEK 293 cells.
-
Francken BJ, Jurzak M, Vanhauwe JF, Luyten WH, Leysen JE. The human 5-ht5A receptor couples to Gi/Go proteins and inhibits adenylate cyclase in HEK 293 cells. Eur J Pharmacol 1998, 361:299-309.
-
(1998)
Eur J Pharmacol
, vol.361
, pp. 299-309
-
-
Francken, B.J.1
Jurzak, M.2
Vanhauwe, J.F.3
Luyten, W.H.4
Leysen, J.E.5
-
135
-
-
0031874682
-
Functional coupling of a recombinant human 5-HT5A receptor to G-proteins in HEK-293 cells.
-
Hurley PT, McMahon RA, Fanning P, O'Boyle KM, Rogers M, Martin F. Functional coupling of a recombinant human 5-HT5A receptor to G-proteins in HEK-293 cells. Br J Pharmacol 1998, 124:1238-1244.
-
(1998)
Br J Pharmacol
, vol.124
, pp. 1238-1244
-
-
Hurley, P.T.1
McMahon, R.A.2
Fanning, P.3
O'Boyle, K.M.4
Rogers, M.5
Martin, F.6
-
136
-
-
0027212940
-
A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation.
-
Ruat M, Traiffort E, Arrang JM, Tardivel-Lacombe J, Diaz J, Leurs R, Schwartz JC. A novel rat serotonin (5-HT6) receptor: molecular cloning, localization and stimulation of cAMP accumulation. Biochem Biophys Res Commun 1993, 193:268-276.
-
(1993)
Biochem Biophys Res Commun
, vol.193
, pp. 268-276
-
-
Ruat, M.1
Traiffort, E.2
Arrang, J.M.3
Tardivel-Lacombe, J.4
Diaz, J.5
Leurs, R.6
Schwartz, J.C.7
-
137
-
-
0029987475
-
Quantitative RT-PCR distribution of serotonin 5-HT6 receptor mRNA in the central nervous system of control or 5,7-dihydroxytryptamine-treated rats.
-
Gerard C, el Mestikawy S, Lebrand C, Adrien J, Ruat M, Traiffort E, Hamon M, Martres MP. Quantitative RT-PCR distribution of serotonin 5-HT6 receptor mRNA in the central nervous system of control or 5, 7-dihydroxytryptamine-treated rats. Synapse 1996, 23:164-173.
-
(1996)
Synapse
, vol.23
, pp. 164-173
-
-
Gerard, C.1
El Mestikawy, S.2
Lebrand, C.3
Adrien, J.4
Ruat, M.5
Traiffort, E.6
Hamon, M.7
Martres, M.P.8
-
138
-
-
0032216591
-
The putative 5-ht6 receptor: localization and function.
-
Sleight AJ, Boess FG, Bos M, Bourson A. The putative 5-ht6 receptor: localization and function. Ann N Y Acad Sci 1998, 861:91-96.
-
(1998)
Ann N Y Acad Sci
, vol.861
, pp. 91-96
-
-
Sleight, A.J.1
Boess, F.G.2
Bos, M.3
Bourson, A.4
-
139
-
-
0032504229
-
Stimulation of type 1 and type 8 Ca2+/calmodulin-sensitive adenylyl cyclases by the Gs-coupled 5-hydroxytryptamine subtype 5-HT7A receptor.
-
Baker LP, Nielsen MD, Impey S, Metcalf MA, Poser SW, Chan G, Obrietan K, Hamblin MW, Storm DR. Stimulation of type 1 and type 8 Ca2+/calmodulin-sensitive adenylyl cyclases by the Gs-coupled 5-hydroxytryptamine subtype 5-HT7A receptor. J Biol Chem 1998, 273:17469-17476.
-
(1998)
J Biol Chem
, vol.273
, pp. 17469-17476
-
-
Baker, L.P.1
Nielsen, M.D.2
Impey, S.3
Metcalf, M.A.4
Poser, S.W.5
Chan, G.6
Obrietan, K.7
Hamblin, M.W.8
Storm, D.R.9
-
140
-
-
33947209946
-
Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line.
-
Nawoschik SP, Olsen M, Smith DL, Khawaja X. Stable expression of adenylyl cyclase 2 leads to the functional rescue of human 5-HT6 receptor in a CHODUKX cell line. J Pharmacol Toxicol Methods 2007, 55:323-331.
-
(2007)
J Pharmacol Toxicol Methods
, vol.55
, pp. 323-331
-
-
Nawoschik, S.P.1
Olsen, M.2
Smith, D.L.3
Khawaja, X.4
-
141
-
-
34250191571
-
Endogenous serotonin excites striatal cholinergic interneurons via the activation of 5-HT 2C, 5-HT6, and 5-HT7 serotonin receptors: implications for extrapyramidal side effects of serotonin reuptake inhibitors.
-
Bonsi P, Cuomo D, Ding J, Sciamanna G, Ulrich S, Tscherter A, Bernardi G, Surmeier DJ, Pisani A. Endogenous serotonin excites striatal cholinergic interneurons via the activation of 5-HT 2C, 5-HT6, and 5-HT7 serotonin receptors: implications for extrapyramidal side effects of serotonin reuptake inhibitors. Neuropsychopharmacology 2007, 32:1840-1854.
-
(2007)
Neuropsychopharmacology
, vol.32
, pp. 1840-1854
-
-
Bonsi, P.1
Cuomo, D.2
Ding, J.3
Sciamanna, G.4
Ulrich, S.5
Tscherter, A.6
Bernardi, G.7
Surmeier, D.J.8
Pisani, A.9
-
142
-
-
34247174396
-
The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn.
-
Yun HM, Kim S, Kim HJ, Kostenis E, Kim JI, Seong JY, Baik JH, Rhim H. The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn. J Biol Chem 2007, 282:5496-5505.
-
(2007)
J Biol Chem
, vol.282
, pp. 5496-5505
-
-
Yun, H.M.1
Kim, S.2
Kim, H.J.3
Kostenis, E.4
Kim, J.I.5
Seong, J.Y.6
Baik, J.H.7
Rhim, H.8
-
143
-
-
77951226972
-
Physical interaction of Jab1 with human serotonin 6 G-protein-coupled receptor and their possible roles in cell survival.
-
Yun HM, Baik JH, Kang I, Jin C, Rhim H. Physical interaction of Jab1 with human serotonin 6 G-protein-coupled receptor and their possible roles in cell survival. J Biol Chem 2010, 285:10016-10029.
-
(2010)
J Biol Chem
, vol.285
, pp. 10016-10029
-
-
Yun, H.M.1
Baik, J.H.2
Kang, I.3
Jin, C.4
Rhim, H.5
-
144
-
-
77957108249
-
Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects.
-
Marcos B, Cabero M, Solas M, Aisa B, Ramirez MJ. Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects. Int J Neuropsychopharmacol 2010, 13:775-784.
-
(2010)
Int J Neuropsychopharmacol
, vol.13
, pp. 775-784
-
-
Marcos, B.1
Cabero, M.2
Solas, M.3
Aisa, B.4
Ramirez, M.J.5
-
146
-
-
4344710330
-
Functional, molecular and pharmacological advances in 5-HT7 receptor research.
-
Hedlund PB, Sutcliffe JG. Functional, molecular and pharmacological advances in 5-HT7 receptor research. Trends Pharmacol Sci 2004, 25:481-486.
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 481-486
-
-
Hedlund, P.B.1
Sutcliffe, J.G.2
-
147
-
-
0037436063
-
5-HT7 receptor-mediated relaxation of the oviduct in nonpregnant proestrus pigs.
-
Inoue M, Kitazawa T, Cao J, Taneike T. 5-HT7 receptor-mediated relaxation of the oviduct in nonpregnant proestrus pigs. Eur J Pharmacol 2003, 461:207-218.
-
(2003)
Eur J Pharmacol
, vol.461
, pp. 207-218
-
-
Inoue, M.1
Kitazawa, T.2
Cao, J.3
Taneike, T.4
-
148
-
-
0035082314
-
A 5-HT(7) receptor-mediated depolarization in the anterodorsal thalamus. II. Involvement of the hyperpolarization-activated current I(h).
-
Chapin EM, Andrade R. A 5-HT(7) receptor-mediated depolarization in the anterodorsal thalamus. II. Involvement of the hyperpolarization-activated current I(h). J Pharmacol Exp Ther 2001, 297:403-409.
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 403-409
-
-
Chapin, E.M.1
Andrade, R.2
-
149
-
-
23944516797
-
5-HT7 receptor is coupled to G α subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology.
-
Kvachnina E, Liu G, Dityatev A, Renner U, Dumuis A, Richter DW, Dityateva G, Schachner M, Voyno-Yasenetskaya TA, Ponimaskin EG. 5-HT7 receptor is coupled to G α subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology. J Neurosci 2005, 25:7821-7830.
-
(2005)
J Neurosci
, vol.25
, pp. 7821-7830
-
-
Kvachnina, E.1
Liu, G.2
Dityatev, A.3
Renner, U.4
Dumuis, A.5
Richter, D.W.6
Dityateva, G.7
Schachner, M.8
Voyno-Yasenetskaya, T.A.9
Ponimaskin, E.G.10
-
150
-
-
0036932987
-
Involvement of T-type calcium channels in the mechanism of action of 5-HT in rat glomerulosa cells: a novel signaling pathway for the 5-HT7 receptor.
-
Lenglet S, Louiset E, Delarue C, Vaudry H, Contesse V. Involvement of T-type calcium channels in the mechanism of action of 5-HT in rat glomerulosa cells: a novel signaling pathway for the 5-HT7 receptor. Endocr Res 2002, 28:651-655.
-
(2002)
Endocr Res
, vol.28
, pp. 651-655
-
-
Lenglet, S.1
Louiset, E.2
Delarue, C.3
Vaudry, H.4
Contesse, V.5
-
151
-
-
18444415156
-
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells.
-
Norum JH, Methi T, Mattingly RR, Levy FO. Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells. FEBS J 2005, 272:2304-2316.
-
(2005)
FEBS J
, vol.272
, pp. 2304-2316
-
-
Norum, J.H.1
Methi, T.2
Mattingly, R.R.3
Levy, F.O.4
-
152
-
-
34147125008
-
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor.
-
Leon-Ponte M, Ahern GP, O'Connell PJ. Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor. Blood 2007, 109:3139-3146.
-
(2007)
Blood
, vol.109
, pp. 3139-3146
-
-
Leon-Ponte, M.1
Ahern, G.P.2
O'Connell, P.J.3
-
153
-
-
0344874709
-
Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac.
-
Lin SL, Johnson-Farley NN, Lubinsky DR, Cowen DS. Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac. J Neurochem 2003, 87:1076-1085.
-
(2003)
J Neurochem
, vol.87
, pp. 1076-1085
-
-
Lin, S.L.1
Johnson-Farley, N.N.2
Lubinsky, D.R.3
Cowen, D.S.4
-
154
-
-
33645113904
-
Reciprocal interaction of serotonin and neuronal activity in regulation of cAMP-responsive element-dependent gene expression.
-
Mahgoub MA, Sara Y, Kavalali ET, Monteggia LM. Reciprocal interaction of serotonin and neuronal activity in regulation of cAMP-responsive element-dependent gene expression. J Pharmacol Exp Ther 2006, 317:88-96.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 88-96
-
-
Mahgoub, M.A.1
Sara, Y.2
Kavalali, E.T.3
Monteggia, L.M.4
-
155
-
-
14844334743
-
Serotonin via 5-HT7 receptors activates p38 mitogen-activated protein kinase and protein kinase C epsilon resulting in interleukin-6 synthesis in human U373 MG astrocytoma cells.
-
Lieb K, Biersack L, Waschbisch A, Orlikowski S, Akundi RS, Candelario-Jalil E, Hull M, Fiebich BL. Serotonin via 5-HT7 receptors activates p38 mitogen-activated protein kinase and protein kinase C epsilon resulting in interleukin-6 synthesis in human U373 MG astrocytoma cells. J Neurochem 2005, 93:549-559.
-
(2005)
J Neurochem
, vol.93
, pp. 549-559
-
-
Lieb, K.1
Biersack, L.2
Waschbisch, A.3
Orlikowski, S.4
Akundi, R.S.5
Candelario-Jalil, E.6
Hull, M.7
Fiebich, B.L.8
-
156
-
-
71749087889
-
Constitutive Gs-mediated, but not G12-mediated, activity of the 5-hydroxytryptamine 5-HT7(a) receptor is modulated by the palmitoylation of its C-terminal domain.
-
Kvachnina E, Dumuis A, Wlodarczyk J, Renner U, Cochet M, Richter DW, Ponimaskin E. Constitutive Gs-mediated, but not G12-mediated, activity of the 5-hydroxytryptamine 5-HT7(a) receptor is modulated by the palmitoylation of its C-terminal domain. Biochim Biophys Acta 2009, 1793:1646-1655.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1646-1655
-
-
Kvachnina, E.1
Dumuis, A.2
Wlodarczyk, J.3
Renner, U.4
Cochet, M.5
Richter, D.W.6
Ponimaskin, E.7
|