The human 5-ht(5A) receptor couples to G(i)/G(o) proteins and inhibits adenylate cyclase in HEK 293 cells

European Journal of Pharmacology

Volumn 361, Issue 2-3, 1998, Pages 299-309

  Francken, Bart J B ^a   Jurzak, Mirek ^a   Vanhauwe, Jurgen F M ^a   Luyten, Walter H M L ^a   Leysen, Josée E ^a  

^a JANSSEN RESEARCH FOUNDATION   (Belgium)

Author keywords

5 ht(5A) receptor; Cyclic adenosine monophosphate; G protein; Guanosine 5' 35S thiotriphosphate binding; Human; Pertussis toxin

Indexed keywords

5 CARBAMOYLTRYPTAMINE; ADENYLATE CYCLASE; CYCLIC AMP; DIHYDROERGOTAMINE; DOPAMINE; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANYLYLIMIDODIPHOSPHATE; LYSERGIDE; METITEPINE; NORADRENALIN; PERTUSSIS TOXIN; RADIOLIGAND; SEROTONIN; SEROTONIN 1A RECEPTOR; 5-CARBOXAMIDOTRYPTAMINE; ADENYLATE CYCLASE TOXIN; BORDETELLA VIRULENCE FACTOR; DRUG DERIVATIVE; RECOMBINANT PROTEIN; SEROTONIN 5 RECEPTOR; SEROTONIN AGONIST; SEROTONIN RECEPTOR;

ARTICLE; CELL STRAIN; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; KIDNEY CELL; PRIORITY JOURNAL; RECEPTOR BINDING; CELL LINE; CELL MEMBRANE; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; METABOLISM; SECOND MESSENGER;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; CELL LINE; CELL MEMBRANE; CYCLIC AMP; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); GUANYLYL IMIDODIPHOSPHATE; HUMANS; LYSERGIC ACID DIETHYLAMIDE; PERTUSSIS TOXIN; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SECOND MESSENGER SYSTEMS; SEROTONIN; SEROTONIN AGONISTS; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0032553120     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(98)00744-4     Document Type: Article

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