Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT 2B-induced, transactivation-mediated ERK1/2 phosphorylation

Psychopharmacology

Volumn 207, Issue 1, 2009, Pages 1-12

  Li, Baoman ^a   Zhang, Shiquen ^a   Li, Min ^a   Hertz, Leif ^a   Peng, Liang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Arachidonic acid; Ca2+ dependent phospholipase A2; Epidermal growth factor; Extracellular regulated kinases 1 and 2; Serotonin; Unipolar depression

Indexed keywords

ARACHIDONIC ACID; FLUOXETINE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASE A2; SEROTONIN; SEROTONIN 2B RECEPTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; ASTROCYTE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLUOXETINE; GENE EXPRESSION REGULATION; INDOLES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PHOSPHOLIPASES A2; PHOSPHORYLATION; RECEPTOR, SEROTONIN, 5-HT2B; RNA, MESSENGER; SEROTONIN UPTAKE INHIBITORS; TIME FACTORS; UREA;

EID: 68049119944     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-009-1631-3     Document Type: Article

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