Proteomic analysis of bioreactor cultures of an antibody expressing CHOGS cell line that promotes high productivity

Journal of Proteomics and Bioinformatics

Volumn 6, Issue 5, 2013, Pages 99-108

  Dorai, Haimanti ^a   Liu, Suli ^b   Yao, Xiang ^a   Wang, Yonghui ^a   Tekindemir, Uelke ^a   Lewis, Michael J ^a   Wu, Shiaw Lin ^b   Hancock, William ^b  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Antibody; CHO GS; DasGip mini bioreactors; Production cell line; Proteomic analysis

Indexed keywords

ACTIN RELATED PROTEIN; ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ALPHA TUBULIN; ANGIOPOIETIN; ANNEXIN; ANTIBODY; BETA ACTIN; BETA TUBULIN; COLLAGEN TYPE 4; COLONY STIMULATING FACTOR 1; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE; GLUTATHIONE TRANSFERASE; HEAT SHOCK PROTEIN; ISOCITRATE DEHYDROGENASE; KERATIN TYPE II; MALATE DEHYDROGENASE (DECARBOXYLATING); PROTEASOME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; RETINAL DEHYDROGENASE; SERINE PROTEINASE INHIBITOR;

ANIMAL CELL; ANTIBODY PRODUCTION; ARTICLE; CELL CULTURE; CELL DENSITY; CELL GROWTH; CELL ISOLATION; CELL METABOLISM; CELL STRAIN; CELL STRAIN CHO GS; CELL VIABILITY; CELLULAR SECRETION; CONTROLLED STUDY; CYTOSKELETON; FED BATCH CULTURE; FED BATCH REACTOR; FEMALE; GENETIC TRANSFECTION; GENOME; MOLECULAR CLONING; NONHUMAN; PROCESS OPTIMIZATION; PRODUCTIVITY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEOMICS; VALIDATION STUDY; WESTERN BLOTTING;

EID: 84878683756     PISSN: None     EISSN: 0974276X     Source Type: Journal    
DOI: 10.4172/jpb.1000268     Document Type: Article

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