메뉴 건너뛰기




Volumn 12, Issue 5, 2012, Pages 615-622

Monoclonal antibody therapeutics: History and future

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; ALEMTUZUMAB; BASILIXIMAB; BELIMUMAB; BEVACIZUMAB; BRENTUXIMAB VEDOTIN; CANAKINUMAB; CATUMAXOMAB; DACLIZUMAB; DENOSUMAB; DRUG ANTIBODY; ECULIZUMAB; EFALIZUMAB; GEMTUZUMAB OZOGAMICIN; GOLIMUMAB; IPILIMUMAB; MONOCLONAL ANTIBODY; NATALIZUMAB; OFATUMUMAB; OMALIZUMAB; PALIVIZUMAB; PANITUMUMAB; PERTUZUMAB; RANIBIZUMAB; RITUXIMAB; TOCILIZUMAB; TRASTUZUMAB; TRASTUZUMAB EMTANSINE; UNINDEXED DRUG; USTEKINUMAB;

EID: 84867331959     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2012.08.001     Document Type: Review
Times cited : (346)

References (58)
  • 1
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • G. Kohler, and C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
    • (1975) Nature , vol.256 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 2
    • 0035210960 scopus 로고    scopus 로고
    • Differences in promiscuity for antibody-FcRn interactions across species: Implications for therapeutic antibodies
    • R.J. Ober, C.G. Radu, V. Ghetie, and E.S. Ward Differences in promiscuity for antibody-FcRn interactions across species: implications for therapeutic antibodies Int Immunol 13 2001 1551 1559
    • (2001) Int Immunol , vol.13 , pp. 1551-1559
    • Ober, R.J.1    Radu, C.G.2    Ghetie, V.3    Ward, E.S.4
  • 3
    • 15244351004 scopus 로고    scopus 로고
    • Overview of monoclonal antibodies in cancer therapy: Present and promise
    • M. Stern, and R. Herrmann Overview of monoclonal antibodies in cancer therapy: present and promise Crit Rev Oncol Hematol 54 2005 11 29
    • (2005) Crit Rev Oncol Hematol , vol.54 , pp. 11-29
    • Stern, M.1    Herrmann, R.2
  • 4
    • 0021716682 scopus 로고
    • Chimeric human antibody molecules: Mouse antigen-binding domains with human constant region domains
    • S.L. Morrison, M.J. Johnson, L.A. Herzenberg, and V.T. Oi Chimeric human antibody molecules: mouse antigen-binding domains with human constant region domains Proc Natl Acad Sci USA 81 1984 6851 6855
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 6851-6855
    • Morrison, S.L.1    Johnson, M.J.2    Herzenberg, L.A.3    Oi, V.T.4
  • 5
    • 33747616656 scopus 로고    scopus 로고
    • Engineering of therapeutic antibodies to minimize immunogenicity and optimize function
    • L.G. Presta Engineering of therapeutic antibodies to minimize immunogenicity and optimize function Adv Drug Deliv Rev 58 2006 640 656
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 640-656
    • Presta, L.G.1
  • 6
    • 0022558297 scopus 로고
    • Replacing the complementarity-determining regions in a human antibody with those from a mouse
    • P.T. Jones, P.H. Dear, J. Foote, M.S. Neuberger, and G. Winter Replacing the complementarity-determining regions in a human antibody with those from a mouse Nature 321 1986 522 525
    • (1986) Nature , vol.321 , pp. 522-525
    • Jones, P.T.1    Dear, P.H.2    Foote, J.3    Neuberger, M.S.4    Winter, G.5
  • 7
    • 0025226085 scopus 로고
    • Phage antibodies: Filamentous phage displaying antibody variable domains
    • J. McCafferty, A.D. Griffiths, G. Winter, and D.J. Chiswell Phage antibodies: filamentous phage displaying antibody variable domains Nature 348 1990 552 554
    • (1990) Nature , vol.348 , pp. 552-554
    • McCafferty, J.1    Griffiths, A.D.2    Winter, G.3    Chiswell, D.J.4
  • 13
    • 0021713342 scopus 로고
    • Production of functional chimaeric mouse/human antibody
    • G.L. Boulianne, N. Hozumi, and M.J. Shulman Production of functional chimaeric mouse/human antibody Nature 312 1984 643 646
    • (1984) Nature , vol.312 , pp. 643-646
    • Boulianne, G.L.1    Hozumi, N.2    Shulman, M.J.3
  • 16
    • 79851475357 scopus 로고    scopus 로고
    • Immunogenicity of protein therapeutics: The key causes, consequences and challenges
    • M.P. Baker, H.M. Reynolds, B. Lumicisi, and C.J. Bryson Immunogenicity of protein therapeutics: the key causes, consequences and challenges Self Nonself 1 2010 314 322
    • (2010) Self Nonself , vol.1 , pp. 314-322
    • Baker, M.P.1    Reynolds, H.M.2    Lumicisi, B.3    Bryson, C.J.4
  • 17
    • 54849437047 scopus 로고    scopus 로고
    • Prediction of immunogenicity: In silico paradigms, ex vivo and in vivo correlates
    • A.S. De Groot, J. McMurry, and L. Moise Prediction of immunogenicity: in silico paradigms, ex vivo and in vivo correlates Curr Opin Pharmacol 8 2008 620 626
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 620-626
    • De Groot, A.S.1    McMurry, J.2    Moise, L.3
  • 18
    • 48649094750 scopus 로고    scopus 로고
    • Fully human antibodies from transgenic mouse and phage display platforms
    • N. Lonberg Fully human antibodies from transgenic mouse and phage display platforms Curr Opin Immunol 20 2008 450 459
    • (2008) Curr Opin Immunol , vol.20 , pp. 450-459
    • Lonberg, N.1
  • 19
    • 77957361348 scopus 로고    scopus 로고
    • Development trends for human monoclonal antibody therapeutics
    • A.L. Nelson, E. Dhimolea, and J.M. Reichert Development trends for human monoclonal antibody therapeutics Nat Rev Drug Discov 9 2010 767 774
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 767-774
    • Nelson, A.L.1    Dhimolea, E.2    Reichert, J.M.3
  • 22
    • 77951886324 scopus 로고    scopus 로고
    • Impact of glycosylation on effector functions of therapeutic IgG
    • R. Abès, and J.L. Teillaud Impact of glycosylation on effector functions of therapeutic IgG Pharmaceuticals 3 2010 146 157
    • (2010) Pharmaceuticals , vol.3 , pp. 146-157
    • Abès, R.1    Teillaud, J.L.2
  • 23
    • 70449727004 scopus 로고    scopus 로고
    • Optimization of Fc-mediated effector functions of monoclonal antibodies
    • W.R. Strohl Optimization of Fc-mediated effector functions of monoclonal antibodies Curr Opin Biotechnol 20 2009 685 691
    • (2009) Curr Opin Biotechnol , vol.20 , pp. 685-691
    • Strohl, W.R.1
  • 24
    • 77951529848 scopus 로고    scopus 로고
    • Therapeutic antibodies for autoimmunity and inflammation
    • A.C. Chan, and P.J. Carter Therapeutic antibodies for autoimmunity and inflammation Nat Rev Immunol 10 2010 301 316
    • (2010) Nat Rev Immunol , vol.10 , pp. 301-316
    • Chan, A.C.1    Carter, P.J.2
  • 27
    • 33747631571 scopus 로고    scopus 로고
    • Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn)
    • W.F. Dall'Acqua, P.A. Kiener, and H. Wu Properties of human IgG1s engineered for enhanced binding to the neonatal Fc receptor (FcRn) J Biol Chem 281 2006 23514 23524
    • (2006) J Biol Chem , vol.281 , pp. 23514-23524
    • Dall'Acqua, W.F.1    Kiener, P.A.2    Wu, H.3
  • 28
    • 36849001338 scopus 로고    scopus 로고
    • Isotype selection in antibody engineering
    • J.G. Salfeld Isotype selection in antibody engineering Nat Biotechnol 25 2007 1369 1372
    • (2007) Nat Biotechnol , vol.25 , pp. 1369-1372
    • Salfeld, J.G.1
  • 32
    • 0031058617 scopus 로고    scopus 로고
    • Intrachain disulfide bond in the core hinge region of human IgG4
    • J.W. Bloom, M.S. Madanat, D. Marriott, T. Wong, and S.Y. Chan Intrachain disulfide bond in the core hinge region of human IgG4 Protein Sci 6 1997 407 415
    • (1997) Protein Sci , vol.6 , pp. 407-415
    • Bloom, J.W.1    Madanat, M.S.2    Marriott, D.3    Wong, T.4    Chan, S.Y.5
  • 33
    • 39749114621 scopus 로고    scopus 로고
    • The effect of a point mutation on the stability of IgG4 as monitored by analytical ultracentrifugation
    • Y. Lu, S.E. Harding, A.J. Rowe, K.G. Davis, B. Fish, P. Varley, C. Gee, and S. Mulot The effect of a point mutation on the stability of IgG4 as monitored by analytical ultracentrifugation J Pharm Sci 97 2008 960 969
    • (2008) J Pharm Sci , vol.97 , pp. 960-969
    • Lu, Y.1    Harding, S.E.2    Rowe, A.J.3    Davis, K.G.4    Fish, B.5    Varley, P.6    Gee, C.7    Mulot, S.8
  • 34
    • 79961118371 scopus 로고    scopus 로고
    • Pharma interest surges in antibody drug conjugates
    • S. Webb Pharma interest surges in antibody drug conjugates Nat Biotechnol 29 2011 297 298
    • (2011) Nat Biotechnol , vol.29 , pp. 297-298
    • Webb, S.1
  • 35
    • 80054742117 scopus 로고    scopus 로고
    • Seattle genetics rare cancer drug sails through accelerated approval
    • L. DeFrancesco Seattle genetics rare cancer drug sails through accelerated approval Nat Biotechnol 29 2011 851 852
    • (2011) Nat Biotechnol , vol.29 , pp. 851-852
    • Defrancesco, L.1
  • 36
    • 79959700509 scopus 로고    scopus 로고
    • Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer
    • T.T. Junttila, G. Li, K. Parsons, G.L. Phillips, and M.X. Sliwkowski Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer Breast Cancer Res Treat 128 2011 347 356
    • (2011) Breast Cancer Res Treat , vol.128 , pp. 347-356
    • Junttila, T.T.1    Li, G.2    Parsons, K.3    Phillips, G.L.4    Sliwkowski, M.X.5
  • 42
    • 76549085643 scopus 로고    scopus 로고
    • Sym004: A novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy
    • M.W. Pedersen, H.J. Jacobsen, K. Koefoed, A. Hey, C. Pyke, J.S. Haurum, and M. Kragh Sym004: a novel synergistic anti-epidermal growth factor receptor antibody mixture with superior anticancer efficacy Cancer Res 70 2010 588 597
    • (2010) Cancer Res , vol.70 , pp. 588-597
    • Pedersen, M.W.1    Jacobsen, H.J.2    Koefoed, K.3    Hey, A.4    Pyke, C.5    Haurum, J.S.6    Kragh, M.7
  • 43
    • 77955342209 scopus 로고    scopus 로고
    • Therapeutic bispecific antibodies: The selection of stable single-chain fragments to overcome engineering obstacles
    • R. Mabry, and M. Snavely Therapeutic bispecific antibodies: the selection of stable single-chain fragments to overcome engineering obstacles IDrugs 13 2010 543 549
    • (2010) IDrugs , vol.13 , pp. 543-549
    • Mabry, R.1    Snavely, M.2
  • 44
    • 77749239974 scopus 로고    scopus 로고
    • Bispecific antibodies for cancer immunotherapy current perspectives
    • D. Müller, and R.E. Kontermann Bispecific antibodies for cancer immunotherapy current perspectives BioDrugs 24 2010 89 98
    • (2010) BioDrugs , vol.24 , pp. 89-98
    • Müller, D.1    Kontermann, R.E.2
  • 45
    • 77951596808 scopus 로고    scopus 로고
    • Catumaxomab: Clinical development and future directions
    • R. Linke, A. Klein, and D. Seimetz Catumaxomab: clinical development and future directions MAbs 2 2010 129 136
    • (2010) MAbs , vol.2 , pp. 129-136
    • Linke, R.1    Klein, A.2    Seimetz, D.3
  • 46
    • 0021832361 scopus 로고
    • Hybrid antibodies can target sites for attack by T cells
    • U.D. Staerz, O. Kanagawa, and M.J. Bevan Hybrid antibodies can target sites for attack by T cells Nature 314 1985 628 631
    • (1985) Nature , vol.314 , pp. 628-631
    • Staerz, U.D.1    Kanagawa, O.2    Bevan, M.J.3
  • 47
    • 58849085569 scopus 로고    scopus 로고
    • BiTE: Teaching antibodies to eng age T-cells for cancer therapy
    • P.A. Baeuerle, P. Kufer, and R. Bargou BiTE: teaching antibodies to eng age T-cells for cancer therapy Curr Opin Mol Ther 11 2009 22 30
    • (2009) Curr Opin Mol Ther , vol.11 , pp. 22-30
    • Baeuerle, P.A.1    Kufer, P.2    Bargou, R.3
  • 48
    • 0036953160 scopus 로고    scopus 로고
    • Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease
    • W.A. Banks, B. Terrell, S.A. Farr, S.M. Robinson, N. Nonaka, and J.E. Morley Passage of amyloid beta protein antibody across the blood-brain barrier in a mouse model of Alzheimer's disease Peptides 23 2002 2223 2226
    • (2002) Peptides , vol.23 , pp. 2223-2226
    • Banks, W.A.1    Terrell, B.2    Farr, S.A.3    Robinson, S.M.4    Nonaka, N.5    Morley, J.E.6
  • 50
    • 33845599378 scopus 로고    scopus 로고
    • Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier
    • H.J. Stemmler, M. Schmitt, A. Willems, H. Bernhard, N. Harbeck, and V. Heinemann Ratio of trastuzumab levels in serum and cerebrospinal fluid is altered in HER2-positive breast cancer patients with brain metastases and impairment of blood-brain barrier Anticancer Drugs 18 2007 23 28
    • (2007) Anticancer Drugs , vol.18 , pp. 23-28
    • Stemmler, H.J.1    Schmitt, M.2    Willems, A.3    Bernhard, H.4    Harbeck, N.5    Heinemann, V.6
  • 51
    • 79960874985 scopus 로고    scopus 로고
    • Strategies for enhancing antibody delivery to the brain
    • R.T. Frank, K.S. Aboody, and J. Najbauer Strategies for enhancing antibody delivery to the brain Biochim Biophys Acta 1816 2011 191 198
    • (2011) Biochim Biophys Acta , vol.1816 , pp. 191-198
    • Frank, R.T.1    Aboody, K.S.2    Najbauer, J.3
  • 52
    • 57449121882 scopus 로고    scopus 로고
    • Getting into the brain: Approaches to enhance brain drug delivery
    • M.M. Patel, B.R. Goyal, S.V. Bhadada, J.S. Bhatt, and A.F. Amin Getting into the brain: approaches to enhance brain drug delivery CNS Drugs 23 2009 35 58
    • (2009) CNS Drugs , vol.23 , pp. 35-58
    • Patel, M.M.1    Goyal, B.R.2    Bhadada, S.V.3    Bhatt, J.S.4    Amin, A.F.5
  • 53
    • 57649136406 scopus 로고    scopus 로고
    • Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS
    • G.A. Silva Nanotechnology approaches to crossing the blood-brain barrier and drug delivery to the CNS BMC Neurosci 10 9 Suppl. 3 2008 S4
    • (2008) BMC Neurosci , vol.10 , Issue.9 SUPPL. 3 , pp. 4
    • Silva, G.A.1
  • 55
    • 74849088013 scopus 로고    scopus 로고
    • IgG-single chain Fv fusion protein therapeutic for Alzheimer's disease: Expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey
    • R.J. Boado, J.Z. Lu, E.K. Hui, and W.M. Pardridge IgG-single chain Fv fusion protein therapeutic for Alzheimer's disease: expression in CHO cells and pharmacokinetics and brain delivery in the rhesus monkey Biotechnol Bioeng 105 2010 627 635
    • (2010) Biotechnol Bioeng , vol.105 , pp. 627-635
    • Boado, R.J.1    Lu, J.Z.2    Hui, E.K.3    Pardridge, W.M.4
  • 56
    • 28244432240 scopus 로고    scopus 로고
    • The blood-brain barrier transmigrating single domain antibody: Mechanisms of transport and antigenic epitopes in human brain endothelial cells
    • A. Abulrob, H. Sprong, P. Van Bergen en Henegouwen, and D. Stanimirovic The blood-brain barrier transmigrating single domain antibody: mechanisms of transport and antigenic epitopes in human brain endothelial cells J Neurochem 95 2005 1201 1214
    • (2005) J Neurochem , vol.95 , pp. 1201-1214
    • Abulrob, A.1    Sprong, H.2    Van Bergen En Henegouwen, P.3    Stanimirovic, D.4
  • 58
    • 0000146003 scopus 로고
    • A theoretical model of gamma-globulin catabolism
    • F.W. Brambell, W.A. Hemmings, and I.G. Morris A theoretical model of gamma-globulin catabolism Nature 203 1964 1352 1354
    • (1964) Nature , vol.203 , pp. 1352-1354
    • Brambell, F.W.1    Hemmings, W.A.2    Morris, I.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.