-
1
-
-
38949175472
-
Thermophilic bacteria
-
Bergey, D. H. (1919) Thermophilic bacteria J. Bacteriol. 4, 301-306
-
(1919)
J. Bacteriol.
, vol.4
, pp. 301-306
-
-
Bergey, D.H.1
-
2
-
-
0030970741
-
Structural basis for thermostability and identification of potential active site residues for adenylate kinases from the archaeal genus Methanococcus
-
Haney, P., Konisky, J., Koretke, K. K., Luthey-Schulten, Z., and Wolynes, P. G. (1997) Structural basis for thermostability and identification of potential active site residues for adenylate kinases from the archaeal genus Methanococcus Proteins 28, 117-130
-
(1997)
Proteins
, vol.28
, pp. 117-130
-
-
Haney, P.1
Konisky, J.2
Koretke, K.K.3
Luthey-Schulten, Z.4
Wolynes, P.G.5
-
3
-
-
0030741375
-
The crystal structure of citrate synthase from the hyperthermophilic Archaeon pyrococcus furiosus at 1.9 Å resolution
-
Russell, R. J. M., Ferguson, J. M. C., Hough, D. W., Danson, M. J., and Taylor, G. L. (1997) The crystal structure of citrate synthase from the hyperthermophilic Archaeon pyrococcus furiosus at 1.9 Å resolution Biochemistry 36, 9983-9994
-
(1997)
Biochemistry
, vol.36
, pp. 9983-9994
-
-
Russell, R.J.M.1
Ferguson, J.M.C.2
Hough, D.W.3
Danson, M.J.4
Taylor, G.L.5
-
4
-
-
0031591389
-
The refined crystal structure of Bacillus cereus oligo-1,6-glucosidase at 2.0 Å resolution: Structural characterization of proline-substitution sites for protein thermostabilization
-
Watanabe, K., Hata, Y., Kizaki, H., Katsube, Y., and Suzuki, Y. (1997) The refined crystal structure of Bacillus cereus oligo-1,6-glucosidase at 2.0 Å resolution: Structural characterization of proline-substitution sites for protein thermostabilization J. Mol. Biol. 269, 142-153
-
(1997)
J. Mol. Biol.
, vol.269
, pp. 142-153
-
-
Watanabe, K.1
Hata, Y.2
Kizaki, H.3
Katsube, Y.4
Suzuki, Y.5
-
5
-
-
0031837178
-
Enhanced thermal stability of Clostridium beijerinckii alcohol dehydrogenase after strategic substitution of amino acid residues with prolines from the homologous thermophilic Thermoanaerobacter brockii alcohol dehydrogenase
-
Bogin, O., Peretz, M., Hacham, Y., Korkhin, Y., Frolow, F., Kalb, A. J., and Burstein, Y. (1998) Enhanced thermal stability of Clostridium beijerinckii alcohol dehydrogenase after strategic substitution of amino acid residues with prolines from the homologous thermophilic Thermoanaerobacter brockii alcohol dehydrogenase Protein Sci. 7, 1156-1163
-
(1998)
Protein Sci.
, vol.7
, pp. 1156-1163
-
-
Bogin, O.1
Peretz, M.2
Hacham, Y.3
Korkhin, Y.4
Frolow, F.5
Kalb, A.J.6
Burstein, Y.7
-
6
-
-
0011186093
-
Protein thermal stability: Hydrogen bonds or internal packing?
-
Vogt, G. and Argos, P. (1997) Protein thermal stability: Hydrogen bonds or internal packing? Folding Des. 2, S40-S46
-
(1997)
Folding Des.
, vol.2
-
-
Vogt, G.1
Argos, P.2
-
7
-
-
0031580199
-
Protein thermal stability, hydrogen bonds, and ion pairs
-
Vogt, G., Woell, S., and Argos, P. (1997) Protein thermal stability, hydrogen bonds, and ion pairs J. Mol. Biol. 269, 631-643
-
(1997)
J. Mol. Biol.
, vol.269
, pp. 631-643
-
-
Vogt, G.1
Woell, S.2
Argos, P.3
-
8
-
-
0029896617
-
An unusual route to thermostability disclosed by the comparison of Thermus thermophilus and Escherichia coli inorganic prophosphatases
-
Salminen, T., Teplyakov, A., Kankare, J., Cooperman, B. S., Lahti, R., and Goldman, A. (1996) An unusual route to thermostability disclosed by the comparison of Thermus thermophilus and Escherichia coli inorganic prophosphatases Protein Sci. 5, 1014-1025
-
(1996)
Protein Sci.
, vol.5
, pp. 1014-1025
-
-
Salminen, T.1
Teplyakov, A.2
Kankare, J.3
Cooperman, B.S.4
Lahti, R.5
Goldman, A.6
-
9
-
-
78049461379
-
Some applications of thermophilies and their enzymes for protein processing
-
Synowiecki, J. (2010) Some applications of thermophilies and their enzymes for protein processing Afr. J. Biotechnol. 9, 7020-7025
-
(2010)
Afr. J. Biotechnol.
, vol.9
, pp. 7020-7025
-
-
Synowiecki, J.1
-
10
-
-
77953386194
-
Temperature denpendence of protein motions in a thermophilic dihydrofolate reductase and its relationship to catalytic efficiency
-
Oyeyemi, O. A., Sours, K. M., Lee, T., Resing, K. A., Ahn, N. G., and Klinman, J. P. (2010) Temperature denpendence of protein motions in a thermophilic dihydrofolate reductase and its relationship to catalytic efficiency Proc. Natl. Acad. Sci. U.S.A. 107, 10074-10079
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 10074-10079
-
-
Oyeyemi, O.A.1
Sours, K.M.2
Lee, T.3
Resing, K.A.4
Ahn, N.G.5
Klinman, J.P.6
-
11
-
-
79953823548
-
A dynamic knockout reveals that conformational fluctuation influence the chemical step of enzyme catalysis
-
Bhabha, G., Lee, J., Ekiert, D. C., Gam, J., Wilson, I. A., Dyson, H. J., Benkovic, S. J., and Wright, P. E. (2011) A dynamic knockout reveals that conformational fluctuation influence the chemical step of enzyme catalysis Science 332, 234-238
-
(2011)
Science
, vol.332
, pp. 234-238
-
-
Bhabha, G.1
Lee, J.2
Ekiert, D.C.3
Gam, J.4
Wilson, I.A.5
Dyson, H.J.6
Benkovic, S.J.7
Wright, P.E.8
-
12
-
-
80052149070
-
Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions
-
Adamczyk, A. J., Cao, J., Kamerlin, S. C. L., and Warshel, A. (2011) Catalysis by dihydrofolate reductase and other enzymes arises from electrostatic preorganization, not conformational motions Proc. Natl. Acad. Sci. U.S.A. 108, 14115-14120
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 14115-14120
-
-
Adamczyk, A.J.1
Cao, J.2
Kamerlin, S.C.L.3
Warshel, A.4
-
13
-
-
0141596172
-
Structural and functional adaptations to extreme temperatures in psychrophilic, mesophilic, and thermophilic DNA ligases
-
Georlette, D., Damien, B., Blaise, V., Depiereux, E., Uversky, V. N., Gerday, C., and Feller, G. (2003) Structural and functional adaptations to extreme temperatures in psychrophilic, mesophilic, and thermophilic DNA ligases J. Biol. Chem. 278, 37015-37023
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37015-37023
-
-
Georlette, D.1
Damien, B.2
Blaise, V.3
Depiereux, E.4
Uversky, V.N.5
Gerday, C.6
Feller, G.7
-
14
-
-
3142653228
-
Structures and analysis of highly homologous psychrophilic, and thermophilic adenylate kinases
-
Bae, E. and Phillips, G. N. (2004) Structures and analysis of highly homologous psychrophilic, and thermophilic adenylate kinases J. Biol. Chem. 279, 28202-28208
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28202-28208
-
-
Bae, E.1
Phillips, G.N.2
-
15
-
-
0032560505
-
Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins
-
Zavodszky, P., Kardos, J., Svingor, A., and Petsko, G. A. (1998) Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins Proc. Natl. Acad. Sci. U.S.A. 95, 7406-7411
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 7406-7411
-
-
Zavodszky, P.1
Kardos, J.2
Svingor, A.3
Petsko, G.A.4
-
16
-
-
37049100967
-
Stereochemistry of reduction of folic-acid using dihydrofolate-reductase
-
Charlton, P. A., Young, D. W., Birdsall, B., Feeney, J., and Roberts, G. C. K. (1979) Stereochemistry of reduction of folic-acid using dihydrofolate-reductase J. Chem. Soc., Chem. Commun. 922-924
-
(1979)
J. Chem. Soc., Chem. Commun.
, pp. 922-924
-
-
Charlton, P.A.1
Young, D.W.2
Birdsall, B.3
Feeney, J.4
Roberts, G.C.K.5
-
17
-
-
37049102352
-
Stereochemistry of reduction of the vitamin folic-acid by dihydrofolate-reductase
-
Charlton, P. A., Young, D. W., Birdsall, B., Feeney, J., and Roberts, G. C. K. (1985) Stereochemistry of reduction of the vitamin folic-acid by dihydrofolate-reductase J. Chem. Soc., Perkin Trans. 1 1349-1353
-
(1985)
J. Chem. Soc., Perkin Trans. 1
, pp. 1349-1353
-
-
Charlton, P.A.1
Young, D.W.2
Birdsall, B.3
Feeney, J.4
Roberts, G.C.K.5
-
18
-
-
78649358299
-
The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed H-transfer
-
Stojković, V., Perissinotti, L. L., Lee, J., Benkovic, S. J., and Kohen, A. (2010) The effect of active-site isoleucine to alanine mutation on the DHFR catalyzed H-transfer Chem. Commun. 46, 8974-8976
-
(2010)
Chem. Commun.
, vol.46
, pp. 8974-8976
-
-
Stojković, V.1
Perissinotti, L.L.2
Lee, J.3
Benkovic, S.J.4
Kohen, A.5
-
19
-
-
0041761262
-
Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima
-
Maglia, G., Javed, M. H., and Allemann, R. K. (2003) Hydride transfer during catalysis by dihydrofolate reductase from Thermotoga maritima Biochem. J. 374, 529-535
-
(2003)
Biochem. J.
, vol.374
, pp. 529-535
-
-
Maglia, G.1
Javed, M.H.2
Allemann, R.K.3
-
20
-
-
0345647102
-
Homo-dimeric recombinant dihydrofolate reductase from Thermotoga maritima shows extreme intrinsic stability
-
Dams, T., Bohm, G., Auerbach, G., Bader, G., Schuring, H., and Jaenicke, R. (1998) Homo-dimeric recombinant dihydrofolate reductase from Thermotoga maritima shows extreme intrinsic stability Biol. Chem. 379, 367-371
-
(1998)
Biol. Chem.
, vol.379
, pp. 367-371
-
-
Dams, T.1
Bohm, G.2
Auerbach, G.3
Bader, G.4
Schuring, H.5
Jaenicke, R.6
-
21
-
-
0033551438
-
Stability and folding of dihydrofolate reductase from the hyperthermophilic bacterium Thermotoga maritima
-
Dams, T. and Jaenicke, R. (1999) Stability and folding of dihydrofolate reductase from the hyperthermophilic bacterium Thermotoga maritima Biochemistry 38, 9169-9178
-
(1999)
Biochemistry
, vol.38
, pp. 9169-9178
-
-
Dams, T.1
Jaenicke, R.2
-
22
-
-
0032145626
-
Purification and characterization of recombinant Thermotoga maritima dihydrofolate reductase
-
Wilquet, V., Gaspar, J. A., van de Lande, M., van de Casteele, M., Legrain, C., Meiering, E. M., and Glansdorff, N. (1998) Purification and characterization of recombinant Thermotoga maritima dihydrofolate reductase Eur. J. Biochem. 255, 628-637
-
(1998)
Eur. J. Biochem.
, vol.255
, pp. 628-637
-
-
Wilquet, V.1
Gaspar, J.A.2
Van De Lande, M.3
Van De Casteele, M.4
Legrain, C.5
Meiering, E.M.6
Glansdorff, N.7
-
23
-
-
71749090188
-
The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer
-
Pijning, T., van Pouderoyen, G., Kluskens, L., van der Oost, J., and Dijkstra, B. W. (2009) The crystal structure of a hyperthermoactive exopolygalacturonase from Thermotoga maritima reveals a unique tetramer FEBS Lett. 583, 3665-3670
-
(2009)
FEBS Lett.
, vol.583
, pp. 3665-3670
-
-
Pijning, T.1
Van Pouderoyen, G.2
Kluskens, L.3
Van Der Oost, J.4
Dijkstra, B.W.5
-
24
-
-
77953879146
-
The temperature dependence of the kinetic isotope effects of dihydrofolate reductase from Thermotoga maritima is influenced by intersubunit interactions
-
Loveridge, E. J. and Allemann, R. K. (2010) The temperature dependence of the kinetic isotope effects of dihydrofolate reductase from Thermotoga maritima is influenced by intersubunit interactions Biochemistry 49, 5390-5396
-
(2010)
Biochemistry
, vol.49
, pp. 5390-5396
-
-
Loveridge, E.J.1
Allemann, R.K.2
-
25
-
-
0034737320
-
The crystal structure of dihydrofolate reductase from Thermotoga maritima: Molecular features of thermostability
-
Dams, T., Auerbach, G., Bader, G., Jacob, U., Ploom, T., Huber, R., and Jaenicke, R. (2000) The crystal structure of dihydrofolate reductase from Thermotoga maritima: Molecular features of thermostability J. Mol. Biol. 297, 659-672
-
(2000)
J. Mol. Biol.
, vol.297
, pp. 659-672
-
-
Dams, T.1
Auerbach, G.2
Bader, G.3
Jacob, U.4
Ploom, T.5
Huber, R.6
Jaenicke, R.7
-
26
-
-
67649610422
-
Effect of dimerization on the stability and catalytic activity of dihydrofolate reductase from the hyperthermophile Thermotoga maritima
-
Loveridge, E. J., Rodriguez, R. J., Swanwick, R. S., and Allemann, R. K. (2009) Effect of dimerization on the stability and catalytic activity of dihydrofolate reductase from the hyperthermophile Thermotoga maritima Biochemistry 48, 5922-5933
-
(2009)
Biochemistry
, vol.48
, pp. 5922-5933
-
-
Loveridge, E.J.1
Rodriguez, R.J.2
Swanwick, R.S.3
Allemann, R.K.4
-
27
-
-
33846889293
-
Molecular dynamics simulation of thermal unfolding of Thermatoga maritima DHFR
-
Pang, J. Y. and Allemann, R. K. (2007) Molecular dynamics simulation of thermal unfolding of Thermatoga maritima DHFR Phys. Chem. Chem. Phys. 9, 711-718
-
(2007)
Phys. Chem. Chem. Phys.
, vol.9
, pp. 711-718
-
-
Pang, J.Y.1
Allemann, R.K.2
-
28
-
-
0033955055
-
Protein dynamics in enzymatic catalysis: Exploration of dihydrofolate reductase
-
Radkiewicz, J. L. and Brooks, C. L. (2000) Protein dynamics in enzymatic catalysis: Exploration of dihydrofolate reductase J. Am. Chem. Soc. 122, 225-231
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 225-231
-
-
Radkiewicz, J.L.1
Brooks, C.L.2
-
29
-
-
0037022683
-
Network of coupled promoting motions in enzyme catalysis
-
Agarwal, F. K., Billeter, S. R., Rajagopalan, P. T. R., Benkovic, S. J., and Hammes-Schiffer, S. (2002) Network of coupled promoting motions in enzyme catalysis Proc. Natl. Acad. Sci. U.S.A. 99, 2794-2799
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 2794-2799
-
-
Agarwal, F.K.1
Billeter, S.R.2
Rajagopalan, P.T.R.3
Benkovic, S.J.4
Hammes-Schiffer, S.5
-
30
-
-
0041821836
-
A perspective on enzyme catalysis
-
Benkovic, S. J. and Hammes-Schiffer, S. (2003) A perspective on enzyme catalysis Science 301, 1196-1202
-
(2003)
Science
, vol.301
, pp. 1196-1202
-
-
Benkovic, S.J.1
Hammes-Schiffer, S.2
-
31
-
-
33745362450
-
Hydride transfer reaction catalyzed by hyperthermophilic dihydrofolate reductase is dominated by quantum mechanical tunneling and is promoted by both inter- and intramonomeric correlated motions
-
Pang, J. Y., Pu, J. Z., Gao, J. L., Truhlar, D. G., and Allemann, R. K. (2006) Hydride transfer reaction catalyzed by hyperthermophilic dihydrofolate reductase is dominated by quantum mechanical tunneling and is promoted by both inter- and intramonomeric correlated motions J. Am. Chem. Soc. 128, 8015-8023
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 8015-8023
-
-
Pang, J.Y.1
Pu, J.Z.2
Gao, J.L.3
Truhlar, D.G.4
Allemann, R.K.5
-
32
-
-
70350561103
-
The role of arginine 28 in catalysis by dihydrofolate reductase from the hyperthermophile Thermotoga maritima
-
Loveridge, E. J., Maglia, G., and Allemann, R. K. (2009) The role of arginine 28 in catalysis by dihydrofolate reductase from the hyperthermophile Thermotoga maritima ChemBioChem 10, 2624-2627
-
(2009)
ChemBioChem
, vol.10
, pp. 2624-2627
-
-
Loveridge, E.J.1
Maglia, G.2
Allemann, R.K.3
-
33
-
-
79955972786
-
Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase
-
Loveridge, E. J. and Allemann, R. K. (2011) Effect of pH on hydride transfer by Escherichia coli dihydrofolate reductase ChemBioChem 12, 1258-1262
-
(2011)
ChemBioChem
, vol.12
, pp. 1258-1262
-
-
Loveridge, E.J.1
Allemann, R.K.2
-
34
-
-
0014027643
-
On mechanism of chemical and enzymatic reduction of folate and dihydrofolate
-
Zakrzewski, S. F. (1966) On mechanism of chemical and enzymatic reduction of folate and dihydrofolate J. Biol. Chem. 241, 2962-2967
-
(1966)
J. Biol. Chem.
, vol.241
, pp. 2962-2967
-
-
Zakrzewski, S.F.1
-
35
-
-
0023668190
-
Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli
-
Fierke, C. A., Johnson, K. A., and Benkovic, S. J. (1987) Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli Biochemistry 26, 4085-4092
-
(1987)
Biochemistry
, vol.26
, pp. 4085-4092
-
-
Fierke, C.A.1
Johnson, K.A.2
Benkovic, S.J.3
-
36
-
-
32944457660
-
Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase
-
Swanwick, R. S., Maglia, G., Tey, L.-H., and Allemann, R. K. (2006) Coupling of protein motions and hydrogen transfer during catalysis by Escherichia coli dihydrofolate reductase Biochem. J. 394, 259-265
-
(2006)
Biochem. J.
, vol.394
, pp. 259-265
-
-
Swanwick, R.S.1
Maglia, G.2
Tey, L.-H.3
Allemann, R.K.4
-
37
-
-
0020466628
-
Kinetic mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli
-
Stone, S. R. and Morrison, J. F. (1982) Kinetic mechanism of the reaction catalyzed by dihydrofolate reductase from Escherichia coli Biochemistry 21, 3757-3765
-
(1982)
Biochemistry
, vol.21
, pp. 3757-3765
-
-
Stone, S.R.1
Morrison, J.F.2
-
38
-
-
0020441466
-
Crystal-structures of Escherichia coli and Lactobacillus casei dihydrofolate-reductase refined at 1.7 Å resolution. 1. General features and binding of methotrexate
-
Bolin, J. T., Filman, D. J., Matthews, D. A., Hamlin, R. C., and Kraut, J. (1982) Crystal-structures of Escherichia coli and Lactobacillus casei dihydrofolate-reductase refined at 1.7 Å resolution. 1. General features and binding of methotrexate J. Biol. Chem. 257, 3650-3662
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 3650-3662
-
-
Bolin, J.T.1
Filman, D.J.2
Matthews, D.A.3
Hamlin, R.C.4
Kraut, J.5
-
39
-
-
77749255402
-
Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms
-
Goihberg, E., Peretz, M., Tel-Or, S., Dym, O., Shimon, L., Frolow, F., and Burstein, Y. (2010) Biochemical and structural properties of chimeras constructed by exchange of cofactor-binding domains in alcohol dehydrogenases from thermophilic and mesophilic microorganisms Biochemistry 49, 1943-1953
-
(2010)
Biochemistry
, vol.49
, pp. 1943-1953
-
-
Goihberg, E.1
Peretz, M.2
Tel-Or, S.3
Dym, O.4
Shimon, L.5
Frolow, F.6
Burstein, Y.7
-
40
-
-
1842531419
-
Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: The altered structure of a mutant enzyme may form the basis of its diminished catalytic performance
-
Swanwick, R. S., Shrimpton, P. J., and Allemann, R. K. (2004) Pivotal role of Gly 121 in dihydrofolate reductase from Escherichia coli: The altered structure of a mutant enzyme may form the basis of its diminished catalytic performance Biochemistry 43, 4119-4127
-
(2004)
Biochemistry
, vol.43
, pp. 4119-4127
-
-
Swanwick, R.S.1
Shrimpton, P.J.2
Allemann, R.K.3
-
41
-
-
0037083390
-
Thermal unfolding molecular dynamics simulation of Escherichia coli dihydrofolate reductase: Thermal stability of protein domains and unfolding pathway
-
Sham, Y. Y., Ma, B. Y., Tsai, C. J., and Nussinov, R. (2002) Thermal unfolding molecular dynamics simulation of Escherichia coli dihydrofolate reductase: Thermal stability of protein domains and unfolding pathway Proteins 46, 308-320
-
(2002)
Proteins
, vol.46
, pp. 308-320
-
-
Sham, Y.Y.1
Ma, B.Y.2
Tsai, C.J.3
Nussinov, R.4
-
42
-
-
0025373255
-
Refolding of Escherichia coli dihydrofolate reductase: Sequential formation of substrate binding sites
-
Frieden, C. (1990) Refolding of Escherichia coli dihydrofolate reductase: Sequential formation of substrate binding sites Proc. Natl. Acad. Sci. U.S.A. 87, 4413-4416
-
(1990)
Proc. Natl. Acad. Sci. U.S.A.
, vol.87
, pp. 4413-4416
-
-
Frieden, C.1
-
43
-
-
23644442411
-
Incresed thermal stability of site-selectively glycosylated dihydrofolate reductase
-
Swanwick, R. S., Daines, A. M., Tey, L. H., Flitsch, S. L., and Allemann, R. K. (2005) Incresed thermal stability of site-selectively glycosylated dihydrofolate reductase ChemBioChem 6, 1338-1340
-
(2005)
ChemBioChem
, vol.6
, pp. 1338-1340
-
-
Swanwick, R.S.1
Daines, A.M.2
Tey, L.H.3
Flitsch, S.L.4
Allemann, R.K.5
-
44
-
-
77951209387
-
Highly site-selective stability increases by glycosylation of dihydrofolate reductase
-
Tey, L. H., Loveridge, E. J., Swanwick, R. S., Flitsch, S. L., and Allemann, R. K. (2010) Highly site-selective stability increases by glycosylation of dihydrofolate reductase FEBS J. 277, 2171-2179
-
(2010)
FEBS J.
, vol.277
, pp. 2171-2179
-
-
Tey, L.H.1
Loveridge, E.J.2
Swanwick, R.S.3
Flitsch, S.L.4
Allemann, R.K.5
-
45
-
-
0242267579
-
Evidence for environmentally coupled hydrogen tunneling during dihydrofolate reductase catalysis
-
Maglia, G. and Allemann, R. K. (2003) Evidence for environmentally coupled hydrogen tunneling during dihydrofolate reductase catalysis J. Am. Chem. Soc. 125, 13372-13373
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 13372-13373
-
-
Maglia, G.1
Allemann, R.K.2
-
46
-
-
0028305058
-
Determination by raman spectroscopy of the pKa of N5 of dihydrofolate bond to dihydrofolate reductase: Mechanistic implications
-
Chen, Y.-Q., Kraut, J., Blakely, R. L., and Callender, R. (1994) Determination by raman spectroscopy of the pKa of N5 of dihydrofolate bond to dihydrofolate reductase: Mechanistic implications Biochemistry 33, 7021-7026
-
(1994)
Biochemistry
, vol.33
, pp. 7021-7026
-
-
Chen, Y.-Q.1
Kraut, J.2
Blakely, R.L.3
Callender, R.4
-
47
-
-
76149110500
-
Solvent effects on catalysis by Escherichia coli dihydrofolate reductase
-
Loveridge, E. J., Tey, L.-H., and Allemann, R. K. (2010) Solvent effects on catalysis by Escherichia coli dihydrofolate reductase J. Am. Chem. Soc. 132, 1137-1143
-
(2010)
J. Am. Chem. Soc.
, vol.132
, pp. 1137-1143
-
-
Loveridge, E.J.1
Tey, L.-H.2
Allemann, R.K.3
-
49
-
-
0031015737
-
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: Crystallographic evidence
-
Sawaya, M. R. and Kraut, J. (1997) Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: Crystallographic evidence Biochemistry 36, 586-603
-
(1997)
Biochemistry
, vol.36
, pp. 586-603
-
-
Sawaya, M.R.1
Kraut, J.2
-
50
-
-
83755168786
-
The role of large-scale motion in catalysis by dihydrofolate reductase
-
Loveridge, E. J., Tey, L.-H., Behiry, E. M., Dawson, W. M., Evans, R. M., Whittaker, S. B.-M., Gunther, U. L., Williams, C., Crump, M. P., and Allemann, R. K. (2011) The role of large-scale motion in catalysis by dihydrofolate reductase J. Am. Chem. Soc. 133, 20561-20570
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 20561-20570
-
-
Loveridge, E.J.1
Tey, L.-H.2
Behiry, E.M.3
Dawson, W.M.4
Evans, R.M.5
Whittaker, S.B.-M.6
Gunther, U.L.7
Williams, C.8
Crump, M.P.9
Allemann, R.K.10
-
51
-
-
84858758329
-
Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis
-
Loveridge, E. J., Behiry, E. M., Guo, J., and Allemann, R. K. (2012) Evidence that a 'dynamic knockout' in Escherichia coli dihydrofolate reductase does not affect the chemical step of catalysis Nat. Chem. 4, 292-297
-
(2012)
Nat. Chem.
, vol.4
, pp. 292-297
-
-
Loveridge, E.J.1
Behiry, E.M.2
Guo, J.3
Allemann, R.K.4
-
52
-
-
0036782099
-
Crystal structure of Thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 Å resolution
-
Kuhn, P., Lesley, S. A., Mathews, I. I., Canaves, J. M., Brinen, L. S., Dai, X. P., Deacon, A. M., Elsliger, M. A., Eshaghi, S., Floyd, R., Godzik, A., Grittini, C., Klock, H. E., Koesema, E., Kovarik, J. M., Kreusch, A. T., McMullan, D., McPhillips, T. M., Miller, M. A., Miller, M., Morse, A., Moy, K., Ouyang, J., Robb, A., Rodrigues, K., Selby, T. L., Spraggon, G., Stevens, R. C., Taylor, S. S., van der Bedem, H., Velasquez, J., Vincnet, J., Wang, X. H., West, B., Wolf, G., Wooley, J., and Wilson, I. A. (2002) Crystal structure of Thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 Å resolution Proteins 49, 142-145
-
(2002)
Proteins
, vol.49
, pp. 142-145
-
-
Kuhn, P.1
Lesley, S.A.2
Mathews, I.I.3
Canaves, J.M.4
Brinen, L.S.5
Dai, X.P.6
Deacon, A.M.7
Elsliger, M.A.8
Eshaghi, S.9
Floyd, R.10
Godzik, A.11
Grittini, C.12
Klock, H.E.13
Koesema, E.14
Kovarik, J.M.15
Kreusch, A.T.16
McMullan, D.17
McPhillips, T.M.18
Miller, M.A.19
Miller, M.20
Morse, A.21
Moy, K.22
Ouyang, J.23
Robb, A.24
Rodrigues, K.25
Selby, T.L.26
Spraggon, G.27
Stevens, R.C.28
Taylor, S.S.29
Van Der Bedem, H.30
Velasquez, J.31
Vincnet, J.32
Wang, X.H.33
West, B.34
Wolf, G.35
Wooley, J.36
Wilson, I.A.37
more..
-
53
-
-
3543039400
-
How oligomerization contributes to the thermostability of an archaeon protein
-
Tanaka, Y., Tsumoto, K., Yasutake, Y., Umetsu, M., Yao, M., Fukada, H., Tanaka, I., and Kumaga, I. (2004) How oligomerization contributes to the thermostability of an archaeon protein J. Biol. Chem. 279, 32957-32967
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 32957-32967
-
-
Tanaka, Y.1
Tsumoto, K.2
Yasutake, Y.3
Umetsu, M.4
Yao, M.5
Fukada, H.6
Tanaka, I.7
Kumaga, I.8
-
54
-
-
0034625317
-
Strengthening the dimerisation interface of Lac repressor increases its thermostability by 40 C
-
Gerk, L. P., Levon, O., and Muller-Hill, B. (2000) Strengthening the dimerisation interface of Lac repressor increases its thermostability by 40 C J. Mol. Biol. 299, 805-812
-
(2000)
J. Mol. Biol.
, vol.299
, pp. 805-812
-
-
Gerk, L.P.1
Levon, O.2
Muller-Hill, B.3
-
55
-
-
0034654087
-
Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima
-
Thoma, R., Hennig, M., Sterner, R., and Kirschner, K. (2000) Structure and function of mutationally generated monomers of dimeric phosphoribosylanthranilate isomerase from Thermotoga maritima Structure 8, 265-276
-
(2000)
Structure
, vol.8
, pp. 265-276
-
-
Thoma, R.1
Hennig, M.2
Sterner, R.3
Kirschner, K.4
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