Thermal unfolding molecular dynamics simulation of Escherichia coli dihydrofolate reductase: Thermal stability of protein domains and unfolding pathway

Proteins: Structure, Function and Genetics

Volumn 46, Issue 3, 2002, Pages 308-320

  Sham, Yuk Yin ^a   Ma, Buyong ^a   Tsai, Chung Jung ^b   Nussinov, Ruth ^a,b,c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b SAIC FREDERICK INC   (United States)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

Dihydrofolate reductase; Folding pathway; Protein folding; Protein stability; Temperature induced unfolding simulation

Indexed keywords

DIHYDROFOLATE REDUCTASE;

CONFERENCE PAPER; ENZYME ANALYSIS; ESCHERICHIA COLI; HIGH TEMPERATURE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; SIMULATION; STRUCTURE ANALYSIS; TEMPERATURE SENSITIVITY; THERMAL ANALYSIS;

COMPUTER SIMULATION; ESCHERICHIA COLI; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; TETRAHYDROFOLATE DEHYDROGENASE; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 0037083390     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/prot.10040     Document Type: Conference Paper

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