The neurochemistry of limbic-hypothalamic circuits regulating sexual receptivity

Handbook of Neurochemistry and Molecular Neurobiology: Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology

Volumn , Issue , 2007, Pages 151-193

  Micevych, Paul ^a   Sinchak, Kevin ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84878631009     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-30405-2_4     Document Type: Chapter

References (490)

1. Aberg ND, Brywe KG, Isgaard J. 2006. Aspects of growth hormone and insulin-like growth factor-I related to neuroprotection, regeneration, and functional plasticity in the adult brain. Scientific WorldJournal 6:53-80.
2. Acosta-Martinez M, Etgen AM. 2002a. Activation of muopioid receptors inhibits lordosis behavior in estrogen and progesterone-primed female rats. Horm Behav 41:88-100.
3. Acosta-Martinez M, Etgen AM. 2002b. The role of deltaopioid receptors in estrogen facilitation of lordosis behavior. Behav Brain Res 136:93-102.
4. Adell A, Carceller A, Artigas F. 1993. In vivo brain dialysis study of the somatodendritic release of serotonin in the Raphe nuclei of the rat: effects of 8-hydroxy-2-(di-n-propylamino) tetralin. J Neurochem 60:1673-1681.
5. Adrian TE, Allen JM, Bloom SR, Ghatei MA, Rossor MN, et al. 1983. Neuropeptide Y distribution in human brain. Nature 306:584-586.
6. Agmo A, Soria P, Paredes R. 1989. GABAergic drugs and lordosis behaviorinthe female rat. Horm Behav 23:368-380.
7. Ahlenius S, Engel J, Eriksson H, Modigh K, Sodersten P. 1972a. Importance of central catecholamines in the mediation of lordosis behaviour in ovariectomized rats treated with estrogen and inhibitors of monoamine synthesis. J Neural Transm 33:247-255.
8. Ahlenius S, Engel J, Eriksson H, Sodersten P. 1972b. Effects of tetrabenazine on lordosis behaviour and on brain monoamines in the female rat. J Neural Transm 33:155-162.
9. Aiello-Zaldivar M, Luine V, Frankfurt M. 1992. 5, 7-DHT facilitated lordosis: effects of 5-HT agonists. Neuroreport 3:542-544.
10. Akesson TR, Micevych PE. 1988. Estrogen concentration by substance P-immunoreactive neurons in the medial basal hypothalamus of the female rat. J Neurosci Res 19:412-419.
11. Akesson TR, Ulibarri C, Truitt S. 1994. Divergent axon collaterals originate in the estrogen receptive ventromedial nucleus of hypothalamus in the rat. J Neurobiol 25:406-414.
12. Akesson TR, Mantyh PW, Manthyh CR, Matt DW, Micevych PE. 1987. Estrous cyclicity of 125I-cholecystokinin octapeptide binding in the ventromedial hypothalamic nucleus. Neuroendocrinology 45:257-262.
13. Alderete MR, Tokarz RR, Crews D. 1980. Luteinizing hormone-releasing hormone and thyrotropin-releasing hormone induction of female sexual receptivity in the lizard, Anolis carolinensis. Neuroendocrinology 30:200-205.
14. Alexander SP, Mathie A, Peters JA. 2004. Guide to receptors and channels, 1st edn. Br J Pharmacol 141(Suppl 1):S1-126.
15. Amico JA, Crowley RS, Insel TR, Thomas A, O'Keefe JA. 1995. Effect of gonadal steroids upon hypothalamic oxytocin expression. Adv Exp Med Biol 395:23-35.
16. Apostolakis EM, Garai J, Lohmann JE, Clark JH, O'Malley BW. 2000. Epidermal growth factor activates reproductive behavior independent of ovarian steroids in female rodents. Mol Endocrinol 14:1086-1098.
17. Apostolakis EM, Lanz R, O'Malley BW. 2004. Pituitary adenylate cyclase-activating peptide: a pivotal modulator of steroid-induced reproductive behavior in female rodents. Mol Endocrinol 18:173-183.
18. Apostolakis EM, Riherd DN, O'Malley BW. 2005. PAC1 receptors mediate pituitary adenylate cyclase-activating polypeptide- and progesterone-facilitated receptivity in female rats. Mol Endocrinol 19:2798-2811.
19. Ardati A, Henningsen RA, Higelin J, Reinscheid RK, Civelli O, et al. 1997. Interaction of [H-3]orphanin FQ and I-125-Tyr14-orphanin FQ with the orphanin FQ receptor: Kinetics and modulation by cations and guanine nucleotides. Mol Pharmacol 51:816-824.
20. Arimura A, Shioda S. 1995. Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors: neuroendocrine and endocrine interaction. Front Neuroendocrinol 16:53-88.
21. Arletti R, Bertolini A. 1985 Oxytocin stimulates lordosis behavior in female rats. Neuropeptides 6:247-253.
22. Asarian L, Geary N. 1999. Cyclic estradiol treatment phasically potentiates endogenous cholecystokinin's satiating action in ovariectomized rats. Peptides 20:445-450.
23. Auger AP, Moffatt CA, Blaustein JD. 1996. Reproductivelyrelevant stimuli induce Fos-immunoreactivity within progestin receptor-containing neurons in localized regions of female rat forebrain. J Neuroendocrinol 8:831-838.
24. Bailey JD, Centers A, Jennes L. 2006. Expression of AMPA receptor subunits (GluR1-GluR4) in gonadotrophinreleasing hormone neurones of young and middle-aged persistently oestrous rats during the steroid-induced luteinising hormone surge. J Neuroendocrinol 18:1-12.
25. Bale TL, Dorsa DM. 1995a. Sex differences in and effects of estrogen on oxytocin receptor messenger ribonucleic acid expression in the ventromedial hypothalamus. Endocrinology 136:27-32.
26. Bale TL, Dorsa DM. 1995b. Regulation of oxytocin receptor messenger ribonucleic acid in the ventromedial hypothalamus by testosterone and its metabolites. Endocrinology 136:5135-5138.
27. Bale TL, Dorsa DM. 1997. Cloning, novel promoter sequence, and estrogen regulation of a rat oxytocin receptor gene. Endocrinology 138:1151-1158.
28. Bale TL, Dorsa DM. 1998. NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells. Brain Res Mol Brain Res 53:130-137.
29. Bale TL, Dorsa DM, Johnston CA. 1995a. Oxytocin receptor mRNA expression in the ventromedial hypothalamus during the estrous cycle. J Neurosci 15:5058-5064.
30. Bale TL, Pedersen CA, Dorsa DM. 1995b. CNS oxytocin receptor mRNA expression and regulation by gonadal steroids. Adv Exp Med Biol 395:269-280.
31. Bale TL, Davis AM, Auger AP, Dorsa DM, McCarthy MM. 2001. CNS region-specific oxytocin receptor expression: importance in regulation of anxiety and sex behavior. J Neurosci 21:2546-2552.
32. Barry J, Hoffman G, Wray S. 1985. LHRH-containing systems. Handbook of Chemical Neuroanatomy, Vol. 4. Bjorklund A. Hokfelt T. Eds. New York: Elsevier; pp. 162-215.
33. Baskin DG, Norwood BJ, Schwartz MW, Koerker DJ. 1995. Estradiol inhibits the increase of hypothalamic neuropeptide Y messenger ribonucleic acid expression induced by weight loss in ovariectomized rats. Endocrinology 136:5547-5554.
34. Baskys A, Fang L, Bayazitov I. 2005. Activation of neuroprotective pathways by metabotropic group I glutamate receptors: a potential target for drug discovery? Ann N Y Acad Sci 1053:55-73.
35. Beach F. 1948. Hormones Behavior. New York: Paul & Hoeber.
36. Beach FA. 1976. Sexual attractivity, proceptivity, and receptivity in female mammals. Horm Behav 7:105-138.
37. Beach FA, Leboeuf BJ. 1967. Coital behavior in dogs. 1. Preferential mating in the bitch. Anim Behav 15:546-558.
38. Becker JB, Rudick CN, Jenkins WJ. 2001. The role of dopamine in the nucleus accumbens and striatum during sexual behavior in the female rat. J Neurosci 21:3236-3241.
39. Bedecs K, Berthold M, Bartfai T. 1995. Galanin-10 years with a neuroendocrine peptide. Int J Biochem Cell Biol 27:337-349.
40. Benelli A, Poggioli R, Luppi P, Ruini L, Bertolini A, et al. 1994. Oxytocin enhances, and oxytocin antagonism decreases, sexual receptivity in intact female rats. Neuropeptides 27:245-250.
41. Beyer C, Gonzalez-Flores O, Gonzalez-Mariscal G. 1997. Progesterone receptor participates in the stimulatory effect of LHRH, prostaglandin E2, and cyclic AMP on lordosis and proceptive behaviours in rats. J Neuroendocrinol 9:609-614.
42. Beyer C, Gonzalez-Flores O, Ramirez-Orduna JM, Gonzalez-Mariscal G. 1999. Indomethacin inhibits lordosis induced by ring A-reduced progestins: possible role of 3alphaoxoreduction in progestin-facilitated lordosis. Horm Behav 35:1-8.
43. Blaustein JD, Erskine MS. 2002. Feminine sexual behavior: cellular integration of hormonal and afferent information in the rodent forebrain. Hormones, Brain and Behavior, Vol 1. Pfaff DW, Ed. New York: Academic Press; pp. 139-214.
44. Blaustein JD, Mani SK. 2006. Feminine sexual behavior from neuroendocrine and molecular neuroendocrine perspectives. Springer; in press. Handbook of Neurochemistry and Molecular Biology. Vol 21. Blaustein JD, Ed. Behavioral Neurochemistry, Neuroendocrinology and Molecular Neurobiology (Latha, A, Series Editor), New York: Springer; in Press.
45. Blaustein JD, Finkbohner R, Delville Y. 1987. Estrogeninduced and estrogen-facilitated female rat sexual behavior is not mediated by progestin receptors. Neuroendocrinology 45:152-159.
46. Bloch GJ, Butler PC, Kohlert JG. 1996. Galanin microinjected into the medial preoptic nucleus facilitates female- and male-typical sexual behaviors in the female rat. Physiol Behav 59:1147-1154.
47. Bloch GJ, Eckersell C, Mills R. 1993. Distribution of galaninimmunoreactive cells within sexually dimorphic components of the medial preoptic area of the male and female rat. Brain Res 620:259-268.
48. Bloch GJ, Babcock AM, Gorski RA, Micevych PE. 1987. Cholecystokinin stimulates and inhibits lordosis behavior in female rats. Physiol Behav 39:217-224.
49. Bloch GJ, Babcock AM, Gorski RA, Micevych PE. 1988. Effects of cholecystokinin on male copulatory behavior and lordosis behavior in male rats. Physiol Behav 43:351-357.
50. Bloch GJ, Butler PC, Eckersell CB, Mills RH. 1998. Gonadal steroid-dependent GAL-IR cells within the medial preoptic nucleus (MPN) and the stimulatory effects of GAL within the MPN on sexual behaviors. Ann N Y Acad Sci 863:188-205.
51. Bloch GJ, Kurth SM, Akesson TR, Micevych PE. 1992. Estrogen-concentrating cells within cell groups of the medial preoptic area: sex differences and co-localization with galanin-immunoreactive cells. Brain Res 595:301-308.
52. Bloch GJ, Dornan WA, Babcock AM, Gorski RA, Micevych PE. 1989. Effects of site-specific CNS microinjection of cholecystokinin on lordosis behavior in the male rat. Physiol Behav 46:725-730.
53. Boling FL, Blandau RJ. 1939. The estrogen-progesterone induction of mating responses in the spayed female rat. Endocrinology 25:359-364.
54. Bondy CA, Cheng CM. 2004. Signaling by insulin-like growth factor 1 in brain. Eur J Pharmacol 490:25-31.
55. Bouret S, Prevot V, Croix D, Jegou S, Vaudry H, et al. 1999. Mu-opioid receptor mRNA expression in proopiomelanocortin neurons of the rat arcuate nucleus. Brain Res Mol Brain Res 70:155-158.
56. Bradley KC, Meisel RL. 2001. Sexual behavior induction of c-Fos in the nucleus accumbens and amphetaminestimulated locomotor activity are sensitized by previous sexual experience in female Syrian hamsters. J Neurosci 21:2123-2130.
57. Bradley KC, Haas AR, Meisel RL. 2005. 6-Hydroxydopamine lesions in female hamsters (Mesocricetus auratus) abolish the sensitized effects of sexual experience on copulatory interactions with males. Behav Neurosci 119:224-232.
58. Brann DW. 1995. Glutamate: a major excitatory transmitter in neuroendocrine regulation. Neuroendocrinology 61:213-225.
59. Brit J Pharmacol 2003. Nomenclature guidelines for authors. Br J Pharmacol 138:725-729.
60. Brom GM, Schwartz NB. 1968. Acute changes in the estrous cycle following ovariectomy in the golden hamster. Neuroendocrinology 3:366-377.
61. Brown ER, Harlan RE, Krause JE. 1990. Gonadal steroid regulation of substance P (SP) and SP-encoding messenger ribonucleic acids in the rat anterior pituitary and hypothalamus. Endocrinology 126:330-340.
62. Bueno J, Pfaff DW. 1976. Single unit recording in hypothalamus and preoptic area of estrogen-treated and untreated ovariectomized female rats. Brain Res 101:67-78.
63. Bunzow JR, Zhang G, Bouvier C, Saez C, Ronnekleiv OK, et al. 1995. Characterization and distribution of a cloned rat mu-opioid receptor. J Neurochem 64:14-24.
64. Butler PC, Mills RH, Bloch GJ. 2001. Inhibition of lordosis behavior in male and female rats by androgens and progesterone. Horm Behav 40:384-395.
65. Butour JL, Moisand C, Mazarguil H, Mollereau C, Meunier JC. 1997. Recognition and activation of the opioid receptor-like ORL 1 receptor by nociceptin, nociceptin analogs and opioids. Eur J Pharmacol 321:97-103.
66. Bylund DB, Eikenberg DC, Hieble JP, Langer SZ, Lefkowitz RJ, et al. 1994. International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol Rev 46:121-136.
67. Caggiula AR, Herndon JG Scanlon R, Jr, Greenstone D, Bradshaw W, et al. 1979. Dissociation of active from immobility components of sexual behavior in female rats by central 6-hydroxydopamine: implications for CA involvement in sexual behavior and sensorimotor responsiveness. Brain Res 172:505-520.
68. Caldwell HK, Albers HE. 2002. The effects of serotonin agonists on the hypothalamic regulation of sexual receptivity in Syrian hamsters. Horm Behav 42:78-84.
69. Caldwell JD, Clemens LG. 1986. Norepinephrine infusions into the medial preoptic area inhibit lordosis behavior. Pharmacol Biochem Behav 24:1015-1023.
70. Caldwell JD, Moe BD. 1999. Conjugated estradiol increases female sexual receptivity in response to oxytocin infused into the medial preoptic area and medial basal hypothalamus. Horm Behav 35:38-46.
71. CaldwellJD, Pedersen CA, Prange A Jr. 1984. Oxytocin facilitates sexual behavior in estrogen-treated ovariectomized rats. J Steroid Biochem 20(6B):1510.
72. Caldwell JD, Prange AJ Jr, Pedersen CA. 1986. Oxytocin facilitates the sexual receptivity of estrogen-treated female rats. Neuropeptides 7:175-189.
73. Caldwell JD, Walker CH, Pedersen CA, Mason GA. 1992. Effects of steroids and mating on central oxytocin receptors. Ann N Y Acad Sci 652:433-436.
74. Caldwell JD, Barakat AS, Smith DD, Hruby VJ, Pedersen CA. 1990. A uterotonic antagonist blocks the oxytocin-induced facilitation of female sexual receptivity. Brain Res 512:291-296.
75. Caldwell JD, Johns JM, Faggin BM, Senger MA, Pedersen CA. 1994. Infusion of an oxytocin antagonist into the medial preoptic area prior to progesterone inhibits sexual receptivity and increases rejection in female rats. Horm Behav 28:288-302.
76. Caldwell JD, Brooks PJ, Jirikowski GF, Barakat S, Lund PK, et al. 1989. Estrogen alters oxytocin mRNA levels in the preoptic area. J Neuroendocrinol 1:273-278.
77. Caldwell JD, Morris MA, Walker CH, Carr RB, Faggin BM, et al. 1996a. Estradiol conjugated to BSA releases oxytocin from synaptosome-containing homogenates from the medial preoptic area-hypothalamus. Horm Metab Res 28:119-121.
78. Caldwell JD, Walker CH, O'Rourke ST, Faggin BM, Morris M, et al. 1996b. Analogies between oxytocin systems of the uterus and brain. Horm Metab Res 28:65-74.
79. Camargo AC, Spadaro AC, Martins AR, Greene LJ. 1982. Brain endo-oligopeptidase B: inactivation of LH-RH by hydrolysis of the Pro9-Gly-NH2 (10) peptide bond. Braz J Med Biol Res 15:239-245.
80. Campfield LA, Smith FJ, Burn P. 1996. The OB protein (leptin) pathway-a link between adipose tissue mass and central neural networks. Horm Metab Res 28:619-632.
81. Canteras NS, Simerly RB, Swanson LW. 1994. Organization of projections from the ventromedial nucleus of the hypothalamus: a Phaseolus vulgaris-leucoagglutinin study in the rat. J Comp Neurol 348:41-79.
82. Canteros G, Rettori V, Franchi A, Genaro A, Cebral E, et al. 1995. Ethanol inhibits luteinizing hormone-releasing hormone (LHRH) secretion by blocking the response of LHRH neuronal terminals to nitric oxide. Proc Natl Acad Sci USA 92:3416-3420.
83. Canteros G, Rettori V, Genaro A, Suburo A, Gimeno M, et al. 1996. Nitric oxide synthase content of hypothalamic explants: increase by norepinephrine and inactivated by NO and cGMP. Proc Natl Acad Sci USA 93:4246-4250.
84. Catania A, Gatti S, Colombo G, Lipton JM. 2004. Targeting melanocortin receptors as a novel strategy to control inflammation. Pharmacol Rev 56:1-29.
85. Caulfield MP, Birdsall NJ. 1998. International Union of Pharmacology. XVII. Classification of muscarinic acetylcholine receptors. Pharmacol Rev 50:279-290.
86. Ceccatelli S, Grandison L, Scott RE, Pfaff DW, Kow LM. 1996. Estradiol regulation of nitric oxide synthase mRNAs in rat hypothalamus. Neuroendocrinology 64:357-363.
87. Chappell PE, Levine JE. 2000. Stimulation of gonadotropinreleasing hormone surges by estrogen. I. Role of hypothalamic progesterone receptors. Endocrinology 141:1477-1485.
88. Chen W, Kelly MA, Opitz-Araya X, Thomas RE, Low MJ, et al. 1997. Exocrine gland dysfunction in MC5-R-deficient mice: evidence for coordinated regulation of exocrine gland function by melanocortin peptides. Cell 91:789-798.
89. Chen Y, Mestek A, Liu J, Yu L. 1993b. Molecular cloning of a rat kappa opioid receptor reveals sequence similarities to the mu and delta opioid receptors. Biochem J 295:625-628.
90. Chen Y, Mestek A, Liu J, Hurley JA, Yu L. 1993a. Molecular cloning and functional expression of a mu-opioid receptor from rat brain. Mol Pharmacol 44:8-12.
91. Chhajlani V, Wikberg JE. 1992. Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA. FEBS Lett 309:417-420.
92. Chhajlani V, Muceniece R, Wikberg JE. 1993. Molecular cloning of a novel human melanocortin receptor. Biochem Biophys Res Commun 195:866-873.
93. Chu HP, Etgen AM. 1997. A potential role of cyclic GMP in the regulation of lordosis behavior of female rats. Horm Behav 32:125-132.
94. Chu HP, Morales JC, Etgen AM. 1999. Cyclic GMP may potentiate lordosis behaviour by progesterone receptor activation. J Neuroendocrinol 11:107-113.
95. Clark JT, Kalra PS, Kalra SP. 1985. Neuropeptide Y stimulates feeding but inhibits sexual behavior in rats. Endocrinology 117:2435-2442.
96. Clark JT, Kalra PS, Crowley WR, Kalra SP. 1984. Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats. Endocrinology 115:427-429.
97. Clarke WP, Maayani S. 1990. Estrogen effects on 5-HT1A receptors in hippocampal membranes from ovariectomized rats: functional and binding studies. Brain Res 518:287-291.
98. Clemens LG, Weaver DR. 1985. The role of gonadal hormone in the activation of feminine sexual behavior. Handbook of Behavioral Neurobiology, Vol. 7. Adler N, Pfaff D, Goy RW, Eds. New York: Plenum Press; pp. 183-227.
99. Clemens LG, Barr P, Dohanich GP. 1989. Cholinergic regulation of female sexual behavior in rats demonstrated by manipulation of endogenous acetylcholine. Physiol Behav 45:437-442.
100. Clemens LG, Dohanich GP, Witcher JA. 1981. Cholinergic influences on estrogen-dependent sexual behavior in female rats. J Comp Physiol Psychol 95:763-770.
101. Clemens LG, Humphrys RR, Dohanich GP. 1980. Cholinergic brain mechanisms and the hormonal regulation of female sexual behavior in the rat. Pharmacol Biochem Behav 13:81-88.
102. Coirini H, Schumacher M, Flanagan LM, McEwen BS. 1991. Transport of estrogen-induced oxytocin receptors in the ventromedial hypothalamus. J Neurosci 11:3317-3324.
103. Corp ES, Greco B, Powers JB, Marin Bivens CL, Wade GN. 2001. Neuropeptide Y inhibits estrous behavior and stimulates feeding via separate receptors in Syrian hamsters. Am J Physiol Regul Integr Comp Physiol 280:R1061-1068.
104. Cragnolini A, Scimonelli T, Celis ME, Schioth HB. 2000. The role of melanocortin receptors in sexual behavior in female rats. Neuropeptides 34:211-215.
105. Daniels D, Flanagan-Cato LM. 2000. Functionally-defined compartments of the lordosis neural circuit in the ventromedial hypothalamus in female rats. J Neurobiol 45:1-13.
106. Daniels D, Miselis RR, Flanagan-Cato LM. 1999. Central neuronal circuit innervating the lordosis-producing muscles defined by transneuronal transport of pseudorabies virus. J Neurosci 19:2823-2833.
107. Daniels D, Miselis RR, Flanagan-Cato LM. 2003. Hypothalamic co-localization of substance P receptor and transneuronal tracer from the lordosis-relevant lumbar epaxial muscles in the female rat. Neurosci Lett 338:111-114.
108. Darland T, Heinricher MM, Grandy DK. 1998. Orphanin FQ/nociceptin: a role in pain and analgesia, but so much more. Trends Neurosci 21:215-221.
109. Darnaudery M, Perez-Martin M, Belizaire G, Maccari S, Garcia-Segura LM. 2006. Insulin-like growth factor 1 reduces age-related disorders induced by prenatal stress in female rats. Neurobiol Aging 27:119-127.
110. Daughaday WH, Rotwein P. 1989. Insulin-like growth factors I and II. Peptide, messenger ribonucleic acid and gene structures, serum, and tissue concentrations. Endocr Rev 10:68-91.
111. Davis BL, Manzanares J, Lookingland KJ, Moore KE, Clemens LG. 1991. Noradrenergic innervation to the VMN or MPN is not necessary for lordosis. Pharmacol Biochem Behav 39:737-742.
112. Davis GA, Kohl R. 1977. The influence of alpha-receptors on lordosis in the female rat. Pharmacol Biochem Behav 6:47-53.
113. Day JR, Morales TH, Lu JK. 1988. Male stimulation of luteinizing hormone surge, progesterone secretion and ovulation in spontaneously persistent-estrous, aging rats. Biol Reprod 38:1019-1026.
114. Desjardins GC, Brawer JR, Beaudet A. 1990. Distribution of mu, delta, and kappa opioid receptors in the hypothalamus of the rat. Brain Res 536:114-123.
115. Dewing P, Sinchak K, Cook M, Micevych P. 2005. Orphanin FQ/Nociceptin facilitation of lordosis in the medial preoptic area and ventromedial nucleus of the hypothalamus. In Society for Neuroscience Meetings, Washington D. C. Abst 320.17.
116. Dhawan BN, Cesselin F, Raghubir R, Reisine T, Bradley PB, et al. 1996. International union of pharmacology. 12. Classification of opioid receptors. Pharmacol Rev 48:567-592.
117. Dickson RB, Huff KK, Spencer EM, Lippman ME. 1986. Induction of epidermal growth factor-related polypeptides by 17 beta-estradiol in MCF-7 human breast cancer cells. Endocrinology 118:138-142.
118. Dingledine R, Borges K, Bowie D, Traynelis SF. 1999. The glutamate receptor ion channels. Pharmacol Rev 51:7-61.
119. Dohanich GP, Clemens LG. 1981. Brain areas implicated in cholinergic regulation of sexual behavior. Horm Behav 15:157-167.
120. Dohanich GP, McMullan DM, Brazier MM. 1990. Cholinergic regulation of sexual behavior in female hamsters. Physiol Behav 47:127-131.
121. Dohanich GP, Barr PJ, Witcher JA, Clemens LG. 1984. Pharmacological and anatomical aspects of cholinergic activation of female sexual behavior. Physiol Behav 32:1021-1026.
122. Dohanich GP, McMullan DM, Cada DA, Mangum KA. 1991. Muscarinic receptor subtypes and sexual behavior in female rats. Pharmacol Biochem Behav 38:115-124.
123. Dohanich GP, Witcher JA, Weaver DR, Clemens LG. 1982. Alteration of muscarinic binding in specific brain areas following estrogen treatment. Brain Res 241:347-350.
124. Dooley CT, Houghten RA. 1996. Orphanin FQ: receptor binding and analog structure activity relationships in rat brain. Life Sci 59:L23-29.
125. Dornan WA, Malsbury CW. 1989. Peptidergic control of male rat sexual behavior: The effects of intracerebral injections of substance P and cholecystokinin. Physiol Behav 46:547-556.
126. Dornan WA, Akesson TR, Micevych PE. 1990. A substance P projection from the VMH to the dorsal midbrain central gray: Implication for lordosis. Brain Res Bull 25:791-796.
127. Dornan WA, Malsbury CW, Penney RB. 1987. Facilitation of lordosis by injection of substance P into the midbrain central gray. Neuroendocrinology 45:498-506.
128. Dornan WA, Bloch GJ, Priest CA, Micevych PE. 1989. Microinjection of cholecystokinin into the medial preoptic nucleus facilitates lordosis behavior in the female rat. Physiol Behav 45:969-974.
129. Dudley CA, Moss RL. 1985. LHRH and mating behavior: sexual receptivity versus sexual preference. Pharmacol Biochem Behav 22:967-972.
130. Dudley CA, Vale W, Rivier J, Moss RL. 1983. Facilitation of sexual receptivity in the female rat by a fragment of the LHRH decapeptide, Ac-LHRH. Neuroendocrinology 36(6):486-488.
131. Duenas M, Torres-Aleman I, Naftolin F, Garcia-Segura LM. 1996. Interaction of insulin-like growth factor-I and estradiol signaling pathways on hypothalamic neuronal differentiation. Neuroscience 74:531-539.
132. Dumont Y, Jacques D, St Pierre JA, Tong Y, Parker R, Herzog H & Quirion R. 2000. Neuropeptide Y, peptide YYand pancreatic polypeptide receptor proteins and mRNAs in mammalian brains. Handbook of Chemical Neuroanatomy, Vol 16. Peptide Receptor, Part1Quirion, R., Bjorklund, A & Hokfelt, T. ed. London, U. K.: Elsevier. pp 375-475.
133. Eckersell CB, Micevych PE. 1997. Opiate receptors modulate estrogen-induced cholecystokinin and tachykinin but not enkephalin mRNA levels in the limbic system and hypothalamus. Neuroscience 80:473-485.
134. Eckersell CB, Popper P, Micevych PE. 1998. Estrogen-induced alteration of mu-opioid receptor immunoreactivity in the medial preoptic nucleus and medial amygdala. J Neurosci 18:3967-3976.
135. Eddy N, Reid J. 1939. Studies of morphine, codeine, and their derivatives VIII. Dihydromorphine (paramorphan), dihydromorphinone (dilaudid), and dihydrocodeine (dicodid). J Pharmacol Exp Ther 52:468-493.
136. Ehlert FJ, Tran LP. 1990. Regional distribution of M1, M2 and non-M1, non-M2 subtypes of muscarinic binding sites in rat brain. J Pharmacol Exp Ther 255:1148-1157.
137. Erskine MS. 1987. Serum 5 alpha-androstane-3 alpha, 17 betadiol increases in response to paced coital stimulation in cycling female rats. Biol Reprod 37:1139-1148.
138. Erskine MS, Hanrahan SB. 1997. Effects of paced mating on c-fos gene expression in the female rat brain. J Neuroendocrinol 9:903-912.
139. Erskine MS, Lehmann ML, Cameron NM, Polston EK. 2004. Co-regulation of female sexual behavior and pregnancy induction: an exploratory synthesis. Behav Brain Res 153:295-315.
140. Etgen AM. 1990. Intrahypothalamic implants of noradrenergic antagonists disrupt lordosis behavior in female rats. Physiol Behav 48:31-36.
141. Etgen AM, Morales JC. 2002. Somatosensory stimuli evoke norepinephrine release in the anterior ventromedial hypothalamus of sexually receptive female rats. J Neuroendocrinology 14:213-218.
142. Everitt BJ, Fuxe K, Hokfelt T. 1974. Inhibitory role of dopamine and 5-hydroxytryptamine in the sexual behaviour of female rats. Eur J Pharmacol 29:187-191.
143. Everitt BJ, Fuxe K, Hokfelt FT, Jonsson G. 1975. Role of monoamines in the control by hormones of sexual receptivity in the female rat. J Comp Physiol Psychol 89:556-572.
144. Fabre-Nys C, Chesneau D, de la Riva C, Hinton MR, Locatelli A, et al. 2003. Biphasic role of dopamine on female sexual behaviour via D2 receptors in the mediobasal hypothalamus. Neuropharmacology 44:354-366.
145. Farmer CJ, Isakson TR, Coy DJ, Renner KJ. 1996. In vivo evidence for progesterone dependent decreases in serotonin release in the hypothalamus and midbrain central grey: relation to the induction of lordosis. Brain Res 711:84-92.
146. Feder HH, Marrone BL. 1977. Progesterone: Its role in the central nervous system as a facilitator and inhibitor of sexual behavior and gonadotropin release. Ann NY Acad Sci 286:331-354.
147. Ferin M, Tempone A, Zimmering PE, Van de Wiele RL. 1969. Effect of antibodies to 17beta-estradiol and progesterone on the estrous cycle of the rat. Endocrinology 85:1070-1078.
148. Fernandez-Galaz MC, Naftolin F, Garcia-Segura LM. 1999. Phasic synaptic remodeling of the rat arcuate nucleus during the estrous cycle depends on insulin-like growth factor-I receptor activation. J Neurosci Res 55:286-292.
149. Fernandez-Guasti A, Larsson K, Beyer C. 1985a. Potentiative action of alpha- and beta-adrenergic receptor stimulation in inducing lordosis behavior. Pharmacol Biochem Behav 22:613-617.
150. Fernandez-Guasti A, Larsson K, Beyer C. 1985b. Prevention of progesterone-induced lordosis behavior by alpha or beta adrenergic antagonists in ovariectomized estrogen-primed rats. Pharmacol Biochem Behav 22:279-282.
151. Fernandez-Guasti A, Rodriguez-Manzo G, Beyer C. 1983. Effect of guanine derivatives on lordosis behavior in estrogen primed rats. Physiol Behav 31:589-592.
152. Fernandez-Guasti A, Ahlenius S, Hjorth S, Larsson K. 1987. Separation of dopaminergic and serotonergic inhibitory mechanisms in the mediation of estrogen-induced lordosis behaviour in the rat. Pharmacol Biochem Behav 27:93-98.
153. Fiorino DF, Phillips AG. 1999. Facilitation of sexual behavior and enhanced dopamine efflux in the nucleus accumbens of male rats after D-amphetamine-induced behavioral sensitization. J Neurosci 19:456-463.
154. Flanagan LM, Lee B, Calizo L. 2006. Co-localization of midbrain projections, progestin receptors, and mating-induced fos in the hypothalamic ventromedial nucleus of the female rat. Horm Behav: 50:52-60.
155. Flanagan LM, Pfaus JG, Pfaff DW, McEwen BS. 1993. Induction of FOS immunoreactivity in oxytocin neurons after sexual activity in female rats. Neuroendocrinology 58:352-358.
156. Foreman MM, Moss RL. 1979. Role of hypothalamic dopaminergic receptors in the control of lordosis behavior in the female rat. Physiol Behav 22:283-289.
157. Fox AS, Olster DH. 2000. Effects of intracerebroventricular leptin administration on feeding and sexual behaviors in lean and obese female Zucker rats. Horm Behav 37:377-387.
158. Fraley GS, Thomas-Smith SE, Acohido BV, Steiner RA, Clifton DK. 2004. Stimulation of sexual behavior in the male rat by galanin-like peptide. Horm Behav 46:551-557.
159. Frankfurt M, McKittrick CR, Mendelson SD, McEwen BS. 1994. Effect of 5, 7-dihydroxytryptamine, ovariectomy and gonadal steroids on serotonin receptor binding in rat brain. Neuroendocrinology 59:245-250.
160. Frankfurt M, Renner K, Azmitia E, Luine V. 1985. Intrahypothalamic 5, 7-dihydroxytryptamine: temporal analysis of effects on 5-hydroxytryptamine content in brain nuclei and on facilitated lordosis behavior. Brain Res 340:127-133.
161. Frye CA, De Bold JF. 1992. Muscimol facilitates sexual receptivity in hamsters when infused into the ventral tegmentum. Pharmacol Biochem Behav 42:879-887.
162. Frye CA, Mermelstein PG, De Bold JF. 1993. Bicuculline infused into the hamster ventral tegmentum inhibits, while sodium valproate facilitates, sexual receptivity. Pharmacol Biochem Behav 46:1-8.
163. Fukuda K, Kato S, Mori K, Nishi M, Takeshima H, et al. 1994. cDNA Cloning and Regional Distribution of a Novel Member of the Opioid Receptor Family. FEBS Lett 343:42-46.
164. Fulwiler C, Saper CB. 1985. Cholectocystokinin-immunoreactive innervation of the ventrome-dial hypothalamusin the rat: Possible substrate for the autonomic regulation of the feeding. Neurosci Lett 53:289-296.
165. Fushimi S, Shirabe T. 2004. Expression of insulin-like growth factors in remyelination following ethidium bromideinduced demyelination in the mouse spinal cord. Neuropathology 24:208-218.
166. Fuxe K, Everett B, Holkfelt T. 1977. Enhancement of sexual behavior in the female rat by nicotine. Pharmacol Biochem Behav 7:147-151.
167. Garcia-Segura LM, Duenas M, Fernandez-Galaz MC, Chowen JA, Argente J, et al. 1996. Interaction of the signalling pathways of insulin-like growth factor-I and sex steroids in the neuroendocrine hypothalamus. Horm Res 46:160-164.
168. Gargiulo PA, Donoso AO. 1995. Interaction between glutamate and luteinizing hormone-releasing hormone (LHRH) in lordosis behavior and luteinizing hormone release (LH): further studies on NMDA receptor mediation. Physiol Behav 58:169-173.
169. Gargiulo PA, Munoz V, Donoso AO. 1992. Inhibition by N-methyl-D-aspartic acid (NMDA) receptor antagonist of lordosis behavior induced by estrogen followed by progesterone or luteinizing hormone-releasing hormone (LHRH) in the rat. Physiol Behav 52:737-739.
170. Getting SJ. 2006. Targeting melanocortin receptors as potential novel therapeutics. Pharmacol Ther 111:1-15.
171. Gonzalez-Flores O, Shu J, Camacho-Arroyo I, Etgen AM. 2004. Regulation of lordosis by cyclic 3', 5'-guanosine monophosphate, progesterone, and its 5alpha-reduced metabolites involves mitogen-activated protein kinase. Endocrinology 145:5560-5567.
172. Gonzalez F, Chang L, Horab T, Stanczyk FZ, Crickard K, et al. 1999. Adrenal dynamic responses to physiologic and pharmacologic adrenocorticotropic hormone stimulation before and after ovarian steroid modulation in women with polycystic ovary syndrome. Fertil Steril 71:439-444.
173. Gonzalez MI, Vaziri S, Wilson CA. 1996. Behavioral effects of alpha-MSH
174. Gonzalez MI, Celis ME, Hole DR, Wilson CA. 1993. Interaction of oestradiol, alpha-melanotrophin and noradrenaline within the ventromedial nucleus in the control of female sexual behaviour. Neuroendocrinology 58:218-226.
175. Gonzalez MI, Greengrass P, Russell M, Wilson CA. 1997. Comparison of serotonin receptor numbers and activity in specific hypothalamic areas of sexually active and inactive female rats. Neuroendocrinology 66:384-392.
176. Gorski RA, Yanase M. 1981. Estrogen facilitation of lordosis behavior in the female rat. Exp Brain Res (Suppl) 3:222-237.
177. Gorzalka BB, Lester GL. 1987. Oxytocin-induced facilitation of lordosis behaviour in rats is progesterone-dependent. Neuropeptides 10:55-65.
178. Gorzalka BB, Brotto LA, Hong JJ. 1999. Corticosterone regulation of 5-HT2A receptor-mediated behaviors: attenuation by melatonin. Physiol Behav 67:439-442.
179. Gorzalka BB, Hanson LA, Brotto LA. 1998. Chronic stress effects on sexual behavior in male and female rats: mediation by 5-HT2A receptors. Pharmacol Biochem Behav 61:405-412.
180. Gorzalka BB, Heddema GM, Lester GL, Hanson LA. 1997. beta-endorphin inhibits and facilitates lordosis behaviour in rats depending on ventricular site of administration. Neuropeptides 31:517-521.
181. Goy RW, Phoenix CH, Young WC. 1966. Inhibitory action in the corpus luteum on the hormonal induction of estrous behavior in the guinea pig. Gen Comp Endocrinol 6:267-275.
182. Grierson JP, James MD, Pearson JR, Wilson CA. 1988. The effect of selective D1 and D2 dopaminergic agents on sexual receptivity in the female rat. Neuropharmacology 27:181-189.
183. Guerrini R, Calo G, Rizzi A, Bianchi C, Lazarus LH, et al. 1997. Address and message sequences for the nociceptin receptor: A structure-activity study of nociceptin-(1-13) - peptide amide. J Med Chem 40:1789-1793.
184. Hall NR, Luttge WG. 1977. Diencephalic sites responsive to prostaglandin E2 facilitation of sexual receptivity in estrogen-primed ovariectomized rats. Brain Res Bull 2:203-207.
185. Hall NR, Luttge WG. 1978. Effects of prostaglandin synthesis inhibitor, indomethacin on estrogen- and estrogen plus progesterone-induced sexual receptivity in ovariectomized rats. Pharmacol Biochem Behav 8:597-602.
186. Hamburger-Bar R, Rigter H. 1975. Apomorphine: facilitation of sexual behaviour in female rats. Eur J Pharmacol 32:357-360.
187. Hansen S, Stanfield E, Everitt B. 1980. The role of ventral bundle noradrenergic neurons in sensory components of sexual behaviour and coitus-induced pseudopregnancy. Nature 286:152-154.
188. Hansen S, Stanfield EJ, Everitt BJ. 1981. The effects of lesions of lateral tegmental noradrenergic neurons on components of sexual behavior and pseudopregnancy in female rats. Neuroscience 6:1105-1117.
189. Healy DP, Orlowski M. 1992. Immunocytochemical localization of endopeptidase 24. 15 in rat brain. Brain Res 571:121-128.
190. Hebert TJ, Menard CS, Dohanich GP. 1995. Inhibition of lordosis in female hamsters and rats by 8-OH-DPAT treatment. Physiol Behav 57:523-527.
191. Hennessey AC, Camak L, Gordon F, Edwards DA. 1990. Connections between the pontine central gray and the ventromedial hypothalamus are essential for lordosis in female rats. Behav Neurosci 104:477-488.
192. Herndon JG Jr, Caggiula AR, Sharp D, Ellis D, Redgate E. 1978. Selective enhancement of the lordotic component of female sexual behavior in rats following destruction of central catecholamine-containing systems. Brain Res 141:137-151.
193. Hilleson-Gayne CK, Clapper JA. 2005. Effects of decreased estradiol-17beta on the serum and anterior pituitary IGF-I system in pigs. J Endocrinol 187:369-378.
194. Hjorth S, Sharp T. 1991. Effect of the 5-HT1A receptor agonist 8-OH-DPAT on the release of 5-HT in dorsal and median raphe-innervated rat brain regions as measured by in vivo microdialysis. Life Sci 48:1779-1786.
195. Hjorth S, Suchowski CS, Galloway MP. 1995. Evidence for 5-HT autoreceptor-mediated, nerve impulse-independent, control of 5-HT synthesis in the rat brain. Synapse 19:170-176.
196. Ho GK, Quadagno DM, Cooke PH, Gorski RA. 1973. Intracranial implants of actinomycin-D: effects on sexual behavior and nucleolar ultrastructure in the rat. Neuroendocrinology 13:47-55.
197. Hokfelt T, Johansson O, Fuxe K, Goldstein M, Park D. 1976. Immunohistochemical studies on the localization and distribution of monoamine neuron systems in the rat brain. I. Tyrosine hydroxylase in the mes- and diencephalon. Med Biol 54:427-453.
198. Holland KL, Abelson L, Micevych PE. 1996. Estrogen stimulates cholecystokinin and preproenkephalin mRNA in the female limbic-hypothalamic circuit during the peripubertal period. Abstr Soc Neurosci Vol. 22:561
199. Holland KL, Popper P, Micevych PE. 1997. Infusion of CCK-A receptor mRNA antisense oligodeoxynucleotides inhibits lordosis behavior. Physiol Behav 62:537-543.
200. Hsu C, Lee JN, Ho ML, Cheng BH, Li PH, et al. 1993. The facilitatory effect of N-methyl-D-aspartate on sexual receptivity in female rats through GnRH release. Acta Endocrinol (Copenh) 128:385-388.
201. Hunter AJ, Hole DR, Wilson CA. 1985. Studies into the dual effects of serotonergic pharmacological agents on female sexual behaviour in the rat: preliminary evidence that endogenous 5HT is stimulatory. Pharmacol Biochem Behav 22:5-13.
202. Huszar D, Lynch CA, Fairchild-Huntress V, Dunmore JH, Fang Q, et al. 1997. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88:131-141.
203. Imura H, Nakao K, Yanaihara N, Katsuura G, Nakamura M. 1986. Potent action of leumorphin on consummatory behaviors in rats: comparison with other opioid peptides. Neuroendocrinology 44:142-148.
204. Imura H, Kato Y, Nakai Y, Nakao K, Tanaka I, et al. 1985. Endogenous opioids and related peptides: from molecular biology to clinical medicine. The Sir Henry Dale lecture for 1985. J Endocrinol 107:147-157.
205. Innes DL, Michal EK. 1970. Effects of progesterone and estrogen on the electrical activity of the limbic system. J Exp Zool 175:487-492.
206. Irving SM, Goy RW, Haning RV, Davis GA. 1981. Prostaglandins, clonidine and sexual receptivity in the guinea pig. Brain Res 204:65-77.
207. Ishihara T, Shigemoto R, Mori K, Takahashi K, Nagata S. 1992. Functional expression and tissue distribution of a novel receptor for vasoactive intestinal polypeptide. Neuron 8:811-819.
208. Itier V, Bertrand D. 2001. Neuronal nicotinic receptors: from protein structure to function. FEBS Lett 504:118-125.
209. Jackson A, Etgen AM. 2001. Estrogen modulates 5-HT1A agonist inhibition of lordosis behavior but not binding of [H-3]-8-OH-DPAT. Pharmacol Biochem Behav 68:221-227.
210. James MD, Hole DR, Wilson CA. 1989. Differential involvement of 5-hydroxytryptamine (5HT) in specific hypothalamic areas in the mediation of steroid-induced changes in gonadotrophin release and sexual behaviour in female rats. Neuroendocrinology 49:561-569.
211. Jaworski DM, Proctor MD. 2000. Developmental regulation of pituitary adenylate cyclase-activating polypeptide and PAC (1) receptor mRNA expression in the rat central nervous system. Brain Res Dev Brain Res 120:27-39.
212. Jirikowski GF, Caldwell JD, Pedersen CA, Stumpf WE. 1988. Estradiol influences oxytocin-immunoreactive brain systems. Neuroscience 25:237-248.
213. Johnson AE, Coirini H, Insel TR, McEwen BS. 1991. The regulation of oxytocin receptor binding in the ventromedial hypothalamic nucleus by testosterone and its metabolites. Endocrinology 128:891-896.
214. Jones JI, Clemmons DR. 1995. Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev 16:3-34.
215. Kalra SP, Clark JT, Sahu A, Dube MG, Kalra PS. 1988. Control of feeding and sexual behaviors by neuropeptide Y: physiological implications. Synapse 2:254-257.
216. Kamat A, Yu WH, Rettori V, McCann SM. 1995. Glutamic acid induces luteinizing hormone releasing hormone release via alpha receptors. Brain Res Bull 37:233-235.
217. Karlin A, Akabas MH. 1995. Toward a structural basis for the function of nicotinic acetylcholine receptors and their cousins. Neuron 15:1231-1244.
218. Kaufman LS, McEwen BS, Pfaff DW. 1988. Cholinergic mechanisms of lordotic behavior in rats. Physiol Behav 43:507-514.
219. Kaur C, Sivakumar V, Dheen ST, Ling EA. 2006. Insulin-like growth factor I and II expression and modulation in amoeboid microglial cells by lipopolysaccharide and retinoic acid. Neuroscience 138:1233-1244.
220. Ke FC, Ramirez VD. 1990. Binding of progesterone to nerve cell membranes of rat brain using progesterone conjugated to 125I-bovine serum albumin as a ligand. J Neurochem 54:467-472.
221. Kendrick KM, Dixson AF. 1985. Luteinizing hormone releasing hormone enhances proceptivity in a primate. Neuroendocrinology 41:449-453.
222. Kimura F, Kawakami M, Nakano H, McCann SM. 1980. Changes in adenosine 3', 5'-monophosphate and guanosine 3', 5'-monophosphate concentrations in the anterior pituitary and hypothalamus during the rat estrous cycle and effects of administration of sodium pentobarbital in proestrus. Endocrinology 106:631-635.
223. Kirby LG, Chou-Green JM, Davis K, Lucki I. 1997. The effects of different stressors on extracellular 5-hydroxytryptamine and 5-hydroxyindoleacetic acid. Brain Res 760:218-230.
224. Ko K. 1934. The influence of opium alkaloids on the sexual cycle of female mice. Taiwan Igk Zeitschr 33:50-62.
225. Ko K. 1935. The influence of opium alkaloids on the sexual cycle of female mice. Jpn J Med Sci IV Pharmacol 8:97-108.
226. Kohlert JG, Rowe RK, Meisel RL. 1997. Intromissive stimulation from the male increases extracellular dopamine release from fluoro-gold-identified neurons within the midbrain of female hamsters. Horm Behav 32:143-154.
227. Kow LM, Pfaff DW. 1985. Estrogen effects on neuronal responsiveness to electrical and neurotransmitter stimulation: an in vitro study on the ventromedial nucleus of the hypothalamus. Brain Res 347:1-10.
228. Kow LM, Pfaff DW. 1996. Thyrotropin-releasing hormone (TRH) has independent excitatory and modulatory actions on lamina IX neurons of lumbosacral spinal cord slices from adult rats. Peptides 17:131-138.
229. Kow LM, Weesner GD, Pfaff DW. 1992. Alpha 1-adrenergic agonists act on the ventromedial hypothalamus to cause neuronal excitation and lordosis facilitation: electrophysiological and behavioral evidence. Brain Res 588:237-245.
230. Kow LM, Tsai YF, Weiland NG, McEwen BS, Pfaff DW. 1995. In vitro electro-pharmacological and autoradiographic analyses of muscarinic receptor subtypes in rat hypothalamic ventromedial nucleus: implications for cholinergic regulation of lordosis. Brain Res 694:29-39.
231. Krause JE, Advis JP, McKelvy JF. 1982. Characterization of the site of cleavage of luteinizing hormone-releasing hormone under conditions of measurement in which LHRH degradation undergoes physiologically related change. Biochem Biophys Res Commun 108:1475-1481.
232. Kubo K, Gorski RA, Kawakami M. 1975. Effects of estrogen on neuronal excitability in the hippocampal-septal-hypothalamic system. Neuroendocrinology 18:176-191.
233. Kudwa AE, Dominguez-Salazar E, Cabrera DM, Sibley DR, Rissman EF. 2005. Dopamine D5 receptor modulates male and female sexual behavior in mice. Psychopharmacology (Berl) 180:206-214.
234. Kulkosky PJ, Glazner GW, Moore HD, Low CA, Woods SC. 1988. Neuropeptide Y: behavioral effects in the golden hamster. Peptides 9:1389-1393.
235. Kurtz MM, Wang R, Clements MK, Cascieri MA, Austin CP, et al. 2002. Identification, localization and receptor characterization of novel mammalian substance P-like peptides. Gene 296:205-212.
236. Labhsetwar AP. 1970. Role of estrogens in ovulation: A study using the estrogen-antagonist, I. C. I. 46, 474. Endocrinology 87:542-551.
237. Lachowicz JE, Shen Y, Monsma FJ Jr, Sibley DR. 1995. Molecular cloning of a novel G protein-coupled receptor related to the opiate receptor family. J Neurochem 64:34-40.
238. Lauber AH, Romano GJ, Mobbs CV, Howells RD, Pfaff DW. 1990. Estradiol induction of proenkephalin messenger RNA in hypothalamus: dose-response and relation to reproductive behavior in the female rat. Brain Res Mol Brain Res 8:47-54.
239. Law PY, Loh HH. 1999. Regulation of opioid receptor activities. J Pharmacol Exp Ther 289:607-624.
240. Lee K, Nicholson JR, McKnight AT. 1997. Nociceptin hyperpolarises neurones in the rat ventromedial hypothalamus. Neurosci Lett 239:37-40.
241. Lee NM, Smith AP. 1980. A protein-lipid model of the opiate receptor. Life Sci 26:1459-1464.
242. Lee WH, Wang GM, Seaman LB, Vannucci SJ. 1996. Coordinate IGF-I and IGFBP5 gene expression in perinatal rat brain after hypoxia-ischemia. J Cereb Blood Flow Metab 16:227-236.
243. Lindstrom JM. 2003. Nicotinic acetylcholine receptors of muscles and nerves: comparison of their structures, functional roles, and vulnerability to pathology. Ann N Y Acad Sci 998:41-52.
244. Lindstrom LH, Meyerson BJ. 1967. The effect of pilocarpine, oxotremorine and arecoline in combination with methylatropine or atropine on hormone activated oestrous behaviour in ovariectomized rats. Psychopharmacologia 11:405-413.
245. Loughlin SE, Leslie FM, Fallon JJ. 1995. Endogenous opioid systems. The Rat Nervous System. Paxinos G. Ed. San Diego: Academic Press; pp. 975-1001.
246. Luine VN, Paden CM. 1982. Effects of monoamine oxidase inhibition on female sexual behavior, serotonin levels and type A and B monoamine oxidase activity. Neuroendocrinology 34:245-251.
247. Luine VN, Renner KJ, Frankfurt M, Azmitia EC. 1984. Facilitated sexual behavior reversed and serotonin restored by raphe nuclei transplanted into denervated hypothalamus. Science 226:1436-1439.
248. Lundberg JM, Terenius L, Hokfelt T, Tatemoto K. 1984. Comparative immunohistochemical and biochemical analysis of pancreatic polypeptide-like peptides with special reference to presence of neuropeptide Y in central and peripheral neurons. J Neurosci 4:2376-2386.
249. Mackay-Sim A, Rose JD. 1986. Removal of the vomeronasal organ impairs lordosis in female hamsters: effect is reversed by luteinising hormone-releasing hormone. Neuroendocrinology 42:489-493.
250. Maggi CA. 1995. The mammalian tachykinin receptors. Gen Pharmacol 26:911-944.
251. Mahesh VB, Brann DW. 1998. Regulation of the preovulatory gonadotropin surge by endogenous steroids. Steroids 63:616-629.
252. Mahachoklertwattana P, Black SM, Kaplan SL, Bristow JD, Grumbach MM. 1994. Nitric oxide synthesized by gonadotropin-releasing hormone neurons is a mediator of N-methyl-D-aspartate (NMDA)-induced GnRH secretion. Endocrinology 135:1709-1712.
253. Maney DL, Richardson RD, Wingfield JC. 1997. Central administration of chicken gonadotropin-releasing hormone-II enhances courtship behavior in a female sparrow. Horm Behav 32:11-18.
254. Mani SK, Blaustein JD, O'Malley BW. 1997. Progesterone receptor function from a behavioral perspective. Horm Behav 31:244-255.
255. Mani SK, Mitchell A, O'Malley BW. 2001. Progesterone receptor and dopamine receptors are required in Delta (9) - tetrahydrocannabinol modulation of sexual receptivity in female rats. Proc Natl Acad Sci USA 98:1249-1254, 1241.
256. Mani SK, Allen JM, Clark JH, Blaustein JD, O'Malley BW. 1994a. Convergent pathways for steroid hormone- and neurotransmitter-induced rat sexual behavior. Science 265:1246-1249.
257. Mani SK, Allen JM, Valeria R, McCann SM, O'Malley BW, et al. 1994b. Nitric Oxide mediates sexual behavior in female rats. Proc Natl Acad Sci USA 91:6468-6472.
258. Mani SK, Blaustein JD, Allen JM, Law SW, O'Malley BW, et al. 1994c. Inhibition of rat sexual behavior by antisense oligonucleotides to the progesterone receptor. Endocrinology 135:1409-1414.
259. Mani SK, Allen JM, Lydon JP, Mulac-Jericevic B, Blaustein JD, et al. 1996. Dopamine requires the unoccupied progesterone receptor to induce sexual behavior in mice [published erratum appears in Mol. Endocrinol 1997 Apr;11 (4) :423]. Mol Endocrinol 10:1728-1737.
260. Mansour A, Fox CA, Thompson RC, Akil H, Watson SJ. 1994b. Mu-opioid receptor mRNA expression in the rat CNS: comparison to mu-receptor binding. Brain Res 643:245-265.
261. Mansour A, Fox CA, Burke S, Meng F, Thompson RC, et al. 1994a. Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study. J Comp Neurol 350:412-438.
262. Marrone BL, Rodriguez-Sierra JF, Feder HH. 1977. Lordosis: inhibiting effects progesterone in the female rat. Horm Behav 8:391-402.
263. Marrone BL, Rodriguez-Sierra JF, Feder HH. 1979. Differential effects of prostaglandins on lordosis behavior in female guinea pigs and rats. Biol Reprod 20:853-861.
264. Maswood N, Caldarola-Pastuszka M, Uphouse L. 1998. Functional integration among 5-hydroxytryptamine receptor families in the control of female rat sexual behavior. Brain Res 802:98-103.
265. Maswood S, Truitt W, Hotema M, Caldarola-Pastuszka M, Uphouse L. 1999. Estrous cycle modulation of extracellular serotonin in mediobasal hypothalamus: role of the serotonin transporter and terminal autoreceptors. Brain Res 831:146-154.
266. Matt DW, Coquelin A, Lu JK. 1987. Neuroendocrine control of luteinizing hormone secretion and reproductive function in spontaneously persistent-estrous aging rats. Biol Reprod 37:1198-1206.
267. Matthews SG, Heavens RP, Sirinathsinghji DJ. 1991. Cellular localization of corticotropin releasing factor mRNA in the ovine brain. Brain Res Mol Brain Res 11:171-176.
268. McCall T, Vallance P. 1992. Nitric oxide takes centre-stage with newly defined roles. Trends Pharmacol Sci 13:1-6.
269. McCarthy MM, Curran GH, Feder HH. 1991a. Excitatory amino acid modulation of lordosis in the rat. Neurosci Lett 126:94-97.
270. McCarthy MM, Malik KF, Feder HH. 1990. Increased GABAergic transmission in medial hypothalamus facilitates lordosis but has the opposite effect in preoptic area. Brain Res 507:40-44.
271. McCarthy MM, Pfaff DW, Schwartz-Giblin S. 1991b. Midbrain central gray GABAA receptor activation enhances, and blockade reduces, sexual behavior in the female rat. Exp Brain Res 86:108-116.
272. McCarthy M, Kleopoulos St, Mobbs C, Pfaff D. 1994a. Infusion of antisense oligodeoxynucleotides to the oxytocin receptor in the ventromedial hypothalamus reduces estrogen-induced sexual receptivity and oxytocin receptor binding in the female rat. Neuronal Reg 59:432-440.
273. 67 mRNAs modulate reproductive behavior in the female rat. Brain Res 636:209-220.
274. McCarthy MM, Masters DB, Fiber JM, Lópex-Colomé A, Beyer C, et al. 1991. GABAergic Control of Receptivity in the Female Rat. Neuroendocrinology 53:473-479.
275. McLean S, Rothman RB, Herkenham M. 1986. Autoradiographic localization of mu- and delta-opiate receptors in the forebrain of the rat. Brain Res 378:49-60.
276. Meisel RL, Camp DM, Robinson TE. 1993. A microdialysis study of ventral striatal dopamine during sexual behavior in female Syrian hamsters. Behav Brain Res 55:151-157.
277. Melis MR, Argiolas A. 1995. Dopamine and sexual behavior. Neurosci Biobehav Rev 19:19-38.
278. Menard CS, Dohanich GP. 1989. Scopolamine inhibition of lordosis in naturally cycling female rats. Physiol Behav 45:819-823.
279. Mendelson SD. 1992. A review and reevaluation of the role of serotonin in the modulation of lordosis behavior in the female rat. Neurosci Biobehav Rev 16:309-350.
280. Mendelson SD, Gorzalka BB. 1985. A facilitatory role for serotonin in the sexual behavior of the female rat. Pharmacol Biochem Behav 22:1025-1033.
281. Mendelson SD, Gorzalka BB. 1987. An improved chamber for the observation and analysis of the sexual behavior of the female rat. Physiol Behav 39:67-71.
282. Mendelson SD, Gorzalka BB. 1990. Sex differences in the effects of 1-(m-trifluoromethylphenyl) piperazine and 1-(m-chlorophenyl) piperazine on copulatory behavior in the rat. Neuropharmacology 29:783-786.
283. Mendelson SD, McEwen BS. 1991. Autoradiographic analyses of the effects of restraint-induced stress on 5-HT1A, 5-HT1C and 5-HT2 receptors in the dorsal hippocampus of male and female rats. Neuroendocrinology 54:454-461.
284. Mendez P, Azcoitia I, Garcia-Segura LM. 2005. Interdependence of oestrogen and insulin-like growth factor-I in the brain: potential for analysing neuroprotective mechanisms. J Endocrinol 185:11-17.
285. Mercer JG, Lawrence CB, Atkinson T. 1996. Hypothalamic NPY and CRF gene expression in the food-deprived Syrian hamster. Physiol Behav 60:121-127.
286. Mermelstein PG, Becker JB. 1995. Increased extracellular dopamine in the nucleus accumbens and striatum the female rat during paced copulatory behavior. Behav Neurosci 109:354-365.
287. Meunier JC. 1997. Nociceptin/orphanin FQ and the opioid receptor-like ORL1 receptor. Eur J Pharmacol 340:1-15.
288. Meunier JC, Mollereau C, Toll L, Suaudeau C, Moisand C, et al. 1995. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377:532-535.
289. Meyers T, Clemens LG. 1985. Dissociation of cholinergic facilitation of feminine sexual behavior and estrogen induction of muscarinic cholinergic receptors. In Conference on Reproductive Behavior, Pacific Grove, CA.
290. Meyerson BJ. 1964. The Effect Of Neuropharmacological Agents On Hormone-Activated Estrus Behaviour In Ovariectomised Rats. Arch Int Pharmacodyn Ther 150:4-33.
291. Micevych P, Sinchak K. 2001. Estrogen and endogenous opioids regulate CCK in reproductive circuits. Peptides 22:1235-1244.
292. Micevych P, Chaban V, Quesada A, Sinchak K. 2002. Oestrogen modulates cholecystokinin: opioid interactions in the nervous system. Pharmacol Toxicol 91:387-397.
293. Micevych P, Sinchak K, Mills RH, Tao L, LaPolt P, et al. 2003a. The luteinizing hormone surge is preceded by an estrogeninduced increase of hypothalamic progesterone in ovariectomized and adrenalectomized rats. Neuroendocrinology 78:29-35.
294. Micevych PE, Ulibarri C. 1992. Development of the limbichypothalamic cholecystokinin circuit: A model of sexual differentiation. Dev Neurosci 14:11-34.
295. Micevych PE, Akesson T, Elde R. 1988a. Distribution of cholecystokinin-immunoreactive cell bodies in the male and female rat: II. Bed nucleus of the stria terminalis and amygdala. J Comp Neurol 269:381-391.
296. Micevych PE, Matt DW, Go VL. 1988b. Concentrations of cholecystokinin, substance P, and bombesin in discrete regions of male and female rat brain: Sex differences and estrogen effects. Exp Neurol 100:416-425.
297. Micevych PE, Yaksh TL, Go VLW. 1982. Opiate-mediated inhibition of the release of cholecystokinin and substance P, but not neurotensin from cat hypothalamic slices. Brain Res 250:283-289.
298. Micevych PE, Eckersell CB, Brecha N, Holland K. 1997. Estrogenic modulation of opiate and cholecystokinin systems in the limbic-hypothalamic circuit. Brain Res Bull 44:335-343.
299. Micevych PE, Eckersell CB, Holland KL, Smith A. 1996. Induction of CCK mRNA levels in the limbic-hypothalamic circuit: Time course and site-specific effects of estrogen. J Neurobiol 30:465-479.
300. Micevych PE, Park SS, Akesson TR, Elde R. 1987. Distribution of cholecystokinin-immunoreactive cell bodies in the male and female rat: I. Hypothalamus. J Comp Neurol 255:124-136.
301. Micevych PE, Rissman EF, Gustafsson JA, Sinchak K. 2003b. Estrogen receptor-alpha is required for estrogen-induced mu-opioid receptor internalization. J Neurosci Res 71:802-810.
302. Micevych PE, Rissman EF, Macias L, Sinchak K. 2000. Estrogen receptor α deficient mice do not internalized muopioid receptors in response to estrogen. In Society of Behavioral Neuroendocrinology Madrid Spain 129-130.
303. Micevych PE, Stroink A, Yaksh T, Go VL. 1986. Immunochemical studies of substance P and cholecystokinin octapeptide recovery in dorsal horn following unilateral lumbosacral ganglionectomy. Somatosens Res 3:239-260.
304. Micevych PE, Yaksh TL, Go VW, Finkelstein JA. 1985. Effect of opiates on the release of cholecystokinin from in vitro hypothalamus and frontal cortex of Zucker lean (Fa/-) and obese (fa/fa) rats. Brain Res 337:382-385.
305. Micevych PE, Abelson L, Fok H, Ulibarri C, Priest CA. 1994. Gonadal steroid control of preprocholecystokinin mRNA expression in the limbic-hypothalamic circuit: Comparison of adult with neonatal steroid treatments. J Neurosci Res 38:386-398.
306. Michel MC, Beck-Sickinger A, Cox H, Doods HN, Herzog H, et al. 1998. XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol Rev 50:143-150.
307. Mills RH, Sinchak K, Mann DM, R, Wright R, Micevych P. 2003. Neuroprogesterone regulation of female reproductive behavior. In Society for Neuroscience, New Orleans, LA, USA. Abst 726.10
308. Mills RH, Sohn RK, Micevych PE. 2004. Estrogen-induced mu-opioid receptor internalization in the medial preoptic nucleus is mediated via neuropeptide Y-Y1 receptor activation in the arcuate nucleus of female rats. J Neurosci 24:947-955.
309. Minami M, Onogi T, Toya T, Katao Y, Hosoi Y, et al. 1994. Molecular cloning and in situ hybridization histochemistry for rat mu-opioid receptor. Neurosci Res 18:315-322.
310. Mollereau C, Parmentier M, Mailleux P, Butour JL, Moisand C, et al. 1994. ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett 341:33-38.
311. Morin LP. 1977. Progesterone: inhibition of rodent behavior. Physiol Behav 18:701-715.
312. Morrell JI, Pfaff DW. 1982. Characterization of estrogen-concentrating hypothalamic neurons by their axonal projections. Science 217:1273-1276.
313. Moss RL. 1974. Relationship between the central regulation of gonadotropins and mating behavior in female rats. Adv Behav Biol 11:55-76.
314. Moss RL, Foreman MM. 1976. Potentiation of lordosis behavior by intrahypothalamic infusion of synthetic luteinizing hormone-releasing hormone. Neuroendocrinology 20:176-181.
315. Moss RL, McCann SM. 1973. Induction of mating behavior in rats by luteinizing hormone-releasing factor. Science 181:177-179.
316. Moss RL, McCann SM. 1975. Action of luteinizing hormonereleasing factor (lrf) in the initiation of lordosis behavior in the estrone-primed ovariectomized female rat. Neuroendocrinology 17:309-318.
317. Mountjoy KG, Robbins LS, Mortrud MT, Cone RD. 1992. The cloning of a family of genes that encode the melanocortin receptors. Science 257:1248-1251.
318. Mountjoy KG, Mortrud MT, Low MJ, Simerly RB, Cone RD. 1994. Localization of the melanocortin-4 receptor (MC4-R) in neuroendocrine and autonomic control circuits in the brain. Mol Endocrinol 8:1298-1308.
319. Myers H, Flynn J. 1931. The effect of chronic morphine poisoning upon growth, the oestrous cycle, and fertility of the white rat. J Pharmacol Exp Ther 41:317-331.
320. Nadler RD. 1970. A biphasic influence of progesterone on sexual receptivity of spayed female rats. Physiol Behav 5:95-97.
321. Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, et al. 1999a. Opioid receptor-like (ORL1) receptor distribution in the rat central nervous system: Comparison of ORL1 receptor mRNA expression with I-125-[(14) Tyr]-orphanin FQ binding. J Comp Neurol 412:563-605.
322. Neal CR, Mansour A, Reinscheid R, Nothacker HP, Civelli O, et al. 1999b. Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat. J Comp Neurol 406:503-547.
323. Neubig RR, Spedding M, Kenakin T, Christopoulos A. 2003. International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacology. Pharmacol Rev 55:597-606.
324. Nguyen Y, Sinchak K, Dewing P, Micevych P. 2006. Orphanin FQ/nociceptin regulation of steroid activation of μ-opioid receptors and sexual behavior in rat models. J Investig Med 54(Suppl 1):71.
325. Nocetto C, Cragnolini AB, Schioth HB, Scimonelli TN. 2004. Evidence that the effect of melanocortins on female sexual behavior in preoptic area is mediated by the MC3 receptor; Participation of nitric oxide. Behav Brain Res 153:537-541.
326. Ogawa S, Kow LM, Pfaff DW. 1992. Effects of Lordosis-Relevant Neuropeptides on Midbrain Periaqueductal Gray Neuronal Activity Invitro. Peptides 13:965-975.
327. Ogawa S, Eng V, Taylor J, Lubahn DB, Korach KS, et al. 1998. Roles of estrogen receptor alpha gene expression in reproduction-related behaviors in female mice. Endocrinology 139:5070-5081.
328. Ohtaki T, Kumano S, Ishibashi Y, Ogi K, Matsui H, et al. 1999. Isolation and cDNA cloning of a novel galanin-like peptide (GALP) from porcine hypothalamus. J Biol Chem 274:37041-37045.
329. Okamura H, Yokosuka M, McEwen BS, Hayashi S. 1994. Colocalization of NADPH-diaphorase and estrogen receptor immunoreactivity in the rat ventromedial hypothalamic nucleus: stimulatory effect of estrogen on NADPH-diaphorase activity. Endocrinology 135:1705-1708.
330. Olschowka JA, Jacobowitz DM. 1983. The coexistence and release of bovine pancreatic polypeptide-like immunoreactivity from noradrenergic superior cervical ganglia neurons. Peptides 4:231-238.
331. Olster DH, Blaustein JD. 1992. Estradiol pulses induce progestin receptors selectively in substance P-immunoreactive neurons in the ventrolateral hypothalamus of female guinea pigs. J Neurobiol 23:293-301.
332. Oro AE, Simerly RB, Swanson LW. 1988. Estrous cycle variations in levels of cholecystokinin immunoreactivity within cells of three interconnected sexually dimorphic forebrain nuclei. Neuroendocrinology 47:225-235.
333. Page NM. 2004. Hemokinins and endokinins. Cell Mol Life Sci 61:1652-1663.
334. Parsons B, Rainbow T, McEewn B. 1984. Organizational effects of testosterone via aromatization on female reproductive behavior and neural proogestine receptors in the rat brain. Endocrinology 115:1412-1417.
335. Patacchini R, Lecci A, Holzer P, Maggi CA. 2004. Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature. Trends Pharmacol Sci 25:1-3.
336. Patterson SJ, Robson LE, Kosterlitz HW. 1983. Classification of opiate receptors. Br Med Bull 39:31-36.
337. Pedersen CA, Boccia ML. 2002. Oxytocin maintains as well as initiates female sexual behavior: effects of a highly selective oxytocin antagonist. Horm Behav 41:170-177.
338. Pedersen CA, Boccia ML. 2006. Vasopressin interactions with oxytocin in the control of female sexual behavior. Neuroscience 139:843-851.
339. Pennefather JN, Lecci A, Candenas ML, Patak E, Pinto FM, et al. 2004. Tachykinins and tachykinin receptors: a growing family. Life Sci 74:1445-1463.
340. Petitti N, Karkanias GB, Etgen AM. 1992. Estradiol selectively regulates alpha 1B-noradrenergic receptors in the hypothalamus and preoptic area. J Neurosci 12:3869-3876.
341. Pfaff DW. 1970. Nature of sex hormone effects on rat sex behavior: Specificity of effects and individual patterns of response. J Comp Physiol Psychol 73:349-358.
342. Pfaff DW. 1973. Luteinizing hormone-releasing factor potentiates lordosis behavior in hypophysectomized ovariectomized female rats. Science 182:1148-1149.
343. Pfaff DW, Keiner M. 1973. Atlas of estradiol-concentrating neurons in the central nervous system of the female rat. J Comp Neurol 151:121-158.
344. Pfaff DW, Sakuma Y. 1979. Facilitation of the lordosis reflex of female rats from the ventromedial nucleus of the hypothalamus. J Physiol 288:189-202.
345. Pfaff DW, Schwartz-Giblin S, McCarthy M, Kow LM. 1994. Cellular and molecular mechanisms of female reproductive behaviors. The Physiology of Reproduction, Vol. 2. Knobil E, Neill, JD, Eds. New York: Raven Press, Ltd; pp. 107-220.
346. Pfaus JG, Gorzalka BB. 1987a. Opioids and sexual behavior. Neurosci Biobehav Rev 11:1-34.
347. Pfaus JG, Gorzalka BB. 1987b. Selective activation of opioid receptors differentially affects lordosis behavior in female rats. Peptides 8:309-317.
348. Pfaus JG, Pfaff DW. 1992a. μ-, δ-, and κ-opioid receptor agonists selectively modulate sexual behaviors in the female rat: Differential dependence on progesterone. Horm Behav 26:457-473.
349. Pfaus JG, Pfaff DW. 1992b. Mu-, delta-, and kappa-opioid receptor agonists selectively modulate sexual behaviors in the female rat: differential dependence on progesterone. Horm Behav 26:457-473.
350. Pfaus JG, Smith WJ, Coopersmith CB. 1999. Appetitive and consummatory sexual behaviors of female rats in bilevel chambers. I. A correlational and factor analysis and the effects of ovarian hormones. Horm Behav 35:224-240.
351. Pfaus JG, Pendleton N, Gorzalka BB. 1986. Dual effect of morphiceptin on lordosis behavior: possible mediation by different opioid receptor subtypes. Pharmacol Biochem Behav 24:1461-1464.
352. Pfaus JG, Damsma G, Wenkstern D, Fibiger HC. 1995. Sexual activity increases dopamine transmission in the nucleus accumbens and striatum of female rats. Brain Res 693:21-30.
353. Pfaus JG, Kleopoulos SP, Mobbs CV, Gibbs RB, Pfaff DW. 1993. Sexual stimulation activates c-fos within estrogenconcentrating regions of the female rat forebrain. Brain Res 624:253-267.
354. Pfaus JG, Shadiack A, Van Soest T, Tse M, Molinoff P. 2004. Selective
355. Pietrzkowski Z, Wernicke D, Porcu P, Jameson BA, Baserga R. 1992. Inhibition of cellular proliferation by peptide analogues of insulin-like growth factor 1. Cancer Res 52:6447-6451.
356. Plant O, Pierce I. 1928. Studies of chronic morphine poisoning in dogs. I General symptoms and behavior during addiction and withdrawal. J Pharmacol Exp Ther 33:329-357.
357. Pons S, Torres-Aleman I. 1993. Estradiol modulates insulinlike growth factor I receptors and binding proteins in neurons from the hypothalamus. J Neuroendocrinol 5:267-271.
358. Priest CA, Vink KL, Micevych PE. 1995. Temporal regulation by estrogen of beta-preprotachykinin mRNA expression in the rat ventromedial nucleus of the hypothalamus. Brain Res Mol Brain Res 28:61-71.
359. Pu S, Kalra PS, Kalra SP. 1998. Ovarian steroid-independent diurnal rhythm in cyclic GMP/nitric oxide efflux in the medial preoptic area: possible role in preovulatory and ovarian steroid-induced LH surge. J Neuroendocrinol 10:617-625.
360. Quadagno DM, McCullough J, Langan R. 1972. The effect of varying amounts of exogenous estradiol benzoate on estrous behavior in the rat. Horm Behav 3:175-179.
361. Quesada A, Etgen AM. 2001. Insulin-like growth factor-1 regulation of alpha (1)-adrenergic receptor signaling is estradiol dependent in the preoptic area and hypothalamus of female rats. Endocrinology 142:599-607.
362. Quesada A, Etgen AM. 2002. Functional interactions between estrogen and insulin-like growth factor-i in the regulation of alpha (1B)-adrenoceptors and female reproductive function. J Neurosci 22:2401-2408.
363. Quesada A, Micevych PE. 2004. Estrogen interacts with the IGF-1 system to protect nigrostriatal dopamine and maintain motoric behavior after 6-hydroxdopamine lesions. J Neurosci Res 75:107-116.
364. Quick MW, Lester RA. 2002. Desensitization of neuronal nicotinic receptors. J Neurobiol 53:457-478.
365. Qureshi GA, Bednar I, Forsberg BG, Sodersten P. 1988. GABA inhibits sexual behaviour in female rats. Neuroscience 27:169-174.
366. Rachman IM, Unnerstall JR, Pfaff DW, Cohen RS. 1998. Regulation of neuronal nitric oxide synthase mRNA in lordosis-relevant neurons of the ventromedial hypothalamus following short-term estrogen treatment. Brain Res Mol Brain Res 59:105-108.
367. Raible LH, Gorzalka BB. 1986. Short and long term inhibitory actions of alpha-melanocyte stimulating hormone on lordosis in rats. Peptides 7:581-586.
368. Rainbow T, Davis P, McEwen B. 1980a. Anisomycin inhibits the activation of sexual behavior by estradiol and progesterone. Brain Res 194:548-555.
369. Rainbow TC, Degroff V, Luine VN, McEwen BS. 1980b. Estradiol 17 beta increases the number of muscarinic receptors in hypothalamic nuclei. Brain Res 198:239-243.
370. Rao IM, Mahesh VB. 1986. Role of progesterone in the modulation of the preovulatory surge of gonadotropins and ovulation in the pregnant mare's serum gonadotropinprimed immature rat and the adult rat. Biol Reprod 35:1154-1161.
371. Reinscheid RK, Ardati A, Monsma FJ, Civelli O. 1996. Structure-Activity Relationship Studies on the Novel Neuropeptide Orphanin FQ. J Biol Chem 271:14163-14168.
372. Reinscheid RK, Higelin J, Henningsen RA, Monsma FJ, Civelli O. 1998. Structures that delineate orphanin FQ and dynorphin A pharmacological selectivities. J Biol Chem 273:1490-1495.
373. Reisine T, Bell GI. 1993. Molecular Biology of Opioid Receptors. Trends Neurosci 16:506-510.
374. Rempel LA, Clapper JA. 2002. Administration of estradiol-17beta increases anterior pituitary IGF-I and relative amounts of serum and anterior pituitary IGF-binding proteins in barrows. J Anim Sci 80:214-224.
375. Rettori V, Canteros G, McCann SM. 1997. Interaction between NO and oxytocin: influence on LHRH release. Braz J Med Biol Res 30:453-457.
376. Rettori V, Kamat A, McCann SM. 1994. Nitric oxide mediates the stimulation of luteinizing-hormone releasing hormone release induced by glutamic acid in vitro. Brain Res Bull 33:501-503.
377. Richmond G, Clemens LG. 1986. Evidence for involvement of midbrain central gray in cholinergic mediation of female sexual receptivity in rats. Behav Neurosci 100:376-380.
378. Rinderknecht E, Humbel RE. 1978. The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem 253:2769-2776.
379. Riskind P, Moss RL. 1983. Midbrain LHRH infusions enhance lordotic behavior in ovariectomized estrogen-primed rats independently of a hypothalamic responsiveness to LHRH. Brain Res Bull 11:481-485.
380. Rissman EF, Wersinger SR, Fugger HN, Foster TC. 1999. Sex with knockout models: behavioral studies of estrogen receptor alpha. Brain Res 835:80-90.
381. Rissman EF, Early AH, Taylor JA, Korach KS, Lubahn DB. 1997. Estrogen receptors are essential for female sexual receptivity. Endocrinology 138:507-510.
382. Rodriguez-Sierra JF, Komisaruk BR. 1978. Lordosis induction in the rat by prostaglandin E2 systemically or intracranially in the absence of ovarian hormones. Prostaglandins 15:513-524.
383. Rodriguez-Sierra JF, Sridaran R, Blake CA. 1980. Monosodium glutamate disruption of behavioral and endocrine function in the female rat. Neuroendocrinology 31:228-235.
384. Romano GJ, Bonner TI, Pfaff DW. 1989. Preprotachykinin gene expression in the mediobasal hypothalamus of estrogen-treated and ovariectomized control rats. Exp Brain Res 76:21-26.
385. Roselli-Rehfuss L, Mountjoy KG, Robbins LS, Mortrud MT, Low MJ, et al. 1993. Identification of a receptor for gamma melanotropin and other proopiomelanocortin peptides in the hypothalamus and limbic system. Proc Natl Acad Sci USA 90:8856-8860.
386. Sabatino FD, Murnane JM, Hoffman RA, McDonald JK. 1987. Distribution of neuropeptide Y-like immunoreactivity in the hypothalamus of the adult golden hamster. J Comp Neurol 257:93-104.
387. Sahlin L, Norstedt G, Eriksson H. 1994. Estrogen regulation of the estrogen receptor and insulinlike growth factor-I in the rat uterus: a potential coupling between effects of estrogen and IGF-I. Steroids 59:421-430.
388. Sakuma Y, Akaishi T. 1987. Cell. size, projection path, and localization of estrogen-sensitive neurons in the rat ventromedial hypothalamus. J Neurophysiol 57:1148-1159.
389. Sakuma Y, Pfaff D. 1979. Mesencephalic mechanisms of integration of female reproductive behavior in the rat. Am J Physiol 237:R285-290.
390. Sakuma Y, Pfaff DW. 1980a. Cells of origin of medullary projections in central gray of rat mesencephalon. J Neurophysiol 44:1002-1011.
391. Sakuma Y, Pfaff DW. 1980b. LH-RH in the mesencephalic central grey can potentiate lordosis reflex of female rats. Nature 283:566-567.
392. Sakuma Y, Pfaff DW. 1982. Properties of ventromedial hypothalamic neurons with axons to midbrain central gray. Exp Brain Res 46:292-300.
393. Sar M, Sahu A, Crowley WR, Kalra SP. 1990. Localization of neuropeptide-Y immunoreactivity in estradiolconcentrating cells in the hypothalamus. Endocrinology 127:2752-2756.
394. Satoh K, Armstrong DM, Fibiger HC. 1983. A comparison of the distribution of central cholinergic neurons as demonstrated by acetylcholinesterase pharmacohistochemistry and choline acetyltransferase immunohistochemistry. Brain Res Bull 11:693-720.
395. Schiml PA, Rissman EF. 2000. Effects of gonadotropinreleasing hormones, corticotropin-releasing hormone, and vasopressin on female sexual behavior. Horm Behav 37:212-220.
396. Schneider JE, Goldman MD, Tang S, Bean B, Ji H, et al. 1998. Leptin indirectly affects estrous cycles by increasing metabolic fuel oxidation. Horm Behav 33:217-228.
397. Schulze HG, Gorzalka BB. 1991. Oxytocin effects on lordosis frequency and lordosis duration following infusion into the medial pre-optic area and ventromedial hypothalamus of female rats. Neuropeptides 18:99-106.
398. Schumacher M, Coirini H, Frankfurt M, McEwen BS. 1989. Localized actions of progesterone in hypothalamus involve oxytocin. Proc Natl Acad Sci USA 86:6798-6801.
399. Schumacher M, Coirini H, McEwen BS, Zaborszky L. 1991. Binding of [3 H] cholecystokinin in the ventromedial hypothalamus is modulated by an afferent brainstem projection but not by ovarian steroids. Brain Res 564:102-108.
400. Schumacher M, Coirini H, Pfaff DW, McEwen BS. 1990. Behavioral effects of progesterone associated with rapid modulation of oxytocin receptors. Science 250:691-694.
401. Schwartz SM, Blaustein JD, Wade GN. 1979. Inhibition of estrogen behavior by progesterone in rats: Role of neural estrogen and progestin receptors. Endocrinology 105:1078-1082.
402. Scimonelli T, Medina F, Wilson C, Celis ME. 2000. Interaction of alpha-melanotropin (alpha-MSH) and noradrenaline in the median eminence in the control of female sexual behavior. Peptides 21:219-223.
403. Seeburg P. 1993. The TiPS/TINS lecture: The molecular biology of mammalian glutamate receptor channels. Trends Pharmacol Sci 14:297-303.
404. Seevers M. 1936. Opiate addiction in the monkey. I. Methods of study. J Pharmacol Exp Ther 56:147-156.
405. Sherwood NM, Krueckl SL, McRory JE. 2000. The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/glucagon superfamily. Endocr Rev 21:619-670.
406. Shimohigashi Y, Hatano R, Fujita T, Nakashima R, Nose T, et al. 1996. Sensitivity of opioid receptor-like receptor ORL1 for chemical modification on nociceptin, a naturally occurring nociceptive peptide. J Biol Chem 271:23642-23645.
407. Shingo AS, Kito S. 2003. Estrogen induces insulin-like growth factor-1 mRNA expression in the immortalized hippocampal cell: determination by quantitative real-time polymerase chain reaction. Neurochem Res 28:1379-1383.
408. Shughrue PJ, Lane MV, Merchenthaler I. 1997. Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system. J Comp Neurol 388:507-525.
409. Sinchak K, Micevych PE. 2001a. Progesterone blockade of estrogen activation of μ-opioid receptors regulates reproductive behavior. J Neurosci 21:5723-5729.
410. Sinchak K, Micevych PE. 2001b. Progesterone blockade of estrogen activation of mu-opioid receptors regulates reproductive behavior. J Neurosci 21:5723-5729.
411. Sinchak K, Micevych P. 2003. Visualizing activation of opioid circuits by internalization of G protein-coupled receptors. Mol Neurobiol 27:197-222.
412. Sinchak K, Romeo HE, Micevych PE. 2006. Site-specific estrogen and progestin regulation of orphanin FQ/nociceptin and nociceptin opioid receptor mRNA expression in the female rat limbic hypothalamic system. J Comp Neurol 496:252-268.
413. Sinchak K, Dewing P, Cook M, Micevych P. Submitted. Release of orphanin FQ/Nociceptin in the medial preoptic nucleus and ventromedial nucleus of the hypothalamus facilitates lordosis. in press.
414. Sinchak K, Hendricks DG, Baroudi R, Micevych PE. 1997. Orphanin FQ/nociceptin in the ventromedial nucleus facilitates lordosis in female rats. Neuroreport 8:3857-3860.
415. Sinchak K, Hipschman S, Cook M, Micevych P. 2004a. Nociceptin/orphanin FQ afferents of the medial preoptic nucleus. In Society for Neuroscience, San Diego. Program No. 423.417.
416. Sinchak K, Mills RH, Eckersell CB, Micevych PE. 2004b. Medial preoptic area delta-opioid receptors inhibit lordosis. Behav Brain Res 155:301-306.
417. Sinchak K, Shahedi K, Dewing P, Micevych P. 2005. Sexual receptivity is reduced in the female mu-opioid receptor knockout mouse. Neuroreport 16:1697-1700.
418. Sinchak K, Yang W, Lino S, Micevych P. 2003. Orphanin FQ infusion into the medial preoptic nucleus facilitates lordosis in estrogen primed female rats, New Orleans, LA. 727.712.
419. Sinchak K, Eckersell C, Quezada V, Norell A, Micevych P. 2000. Preproenkephalin mRNA levels are regulated by acute stress and estrogen stimulation. Physiol Behav 69:425-432.
420. Sirinathsinghji DJ. 1984. Modulation of lordosis behavior of female rats by naloxone, beta-endorphin and its antiserum in the mesencephalic central gray: possible mediation via GnRH. Neuroendocrinology 39:222-230.
421. Sirinathsinghji DJ. 1985. Modulation of lordosis behaviour in the female rat by corticotropin releasing factor, beta-endorphin and gonadotropin releasing hormone in the mesencephalic central gray. Brain Res 336:45-55.
422. Sirinathsinghji DJS. 1986. Regulation of lordosis behavior in the female rat by corticotropin-releasing factor, beta-endorphin/corticotropin and luteinizing hormonereleasing hormone neuronal systems in the medial preoptic area. Brain Res 375:149-156.
423. Sirinathsinghji DJ, Whittington PE, Audsley A, Fraser HM. 1983. β-Endorphin regulates lordosis in female rats by modulating Lh-Rh release. Nature 301:62-64.
424. Smith A, Lee N, Loh H. 1983. The multiple-site beta-endorphin receptor. Trends Pharmacol Sci 4:163-164.
425. Smythies J. 2005. Section II. The dopamine system. Int Rev Neurobiol 64:123-172.
426. Sodersten P, Eneroth P. 1981. Serum levels of oestradiol-17 beta and progesterone in relation to receptivity in intact and ovariectomized rats. J Endocrinol 89:45-54.
427. Sodersten P, De Vries GJ, Buijs RM, Melin P. 1985. A daily rhythm in behavioral vasopressin sensitivity and brain vasopressin concentrations. Neurosci Lett 58:37-41.
428. Sodersten P, Henning M, Melin P, Ludlin S. 1983. Vasopressin alters female sexual behaviour by acting on the brain independently of alterations in blood pressure. Nature 301:608-610.
429. Spragg S. 1940. Morphine addiction in chimpanzees. Comp Psychol Monogr 15:132-190.
430. Sprouse JS, Aghajanian GK. 1987. Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists. Synapse 1:3-9.
431. Stanley BG, Leibowitz SF. 1985. Neuropeptide Y injected in the paraventricular hypothalamus: a powerful stimulant of feeding behavior. Proc Natl Acad Sci USA 82:3940-3943.
432. Suda M, Nakao K, Sakamoto M, Morii N, Sugawara A, et al. 1986. Changes in the immunoreactivities of an opioid peptide leumorphin in the hypothalamus and anterior pituitary during the estrous cycle of the rat and their relation to sexual behavior. Brain Res 374:236-243.
433. Sumner BE, Fink G. 1997. The density of 5-hydoxytryptamine2A receptors in forebrain is increased at pro-oestrus in intact female rats. Neurosci Lett 234:7-10.
434. Sumner BE, Grant KE, Rosie R, Hegele-Hartung C, Fritzemeier KH, et al. 1999. Effects of tamoxifen on serotonin transporter and 5-hydroxytryptamine (2A) receptor binding sites and mRNA levels in the brain of ovariectomized rats with or without acute estradiol replacement. Brain Res Mol Brain Res 73:119-128.
435. Swanson LW, Mogenson GJ, Simerly RB, Wu M. 1987. Anatomical and electrophysiological evidence for a projection from the medial preoptic area to the 'mesencephalic and subthalamic locomotor regions' in the rat. Brain Res 405:108-122.
436. Swanson LW, Sawchenko PE, Rivier J, Vale WW. 1983. Organization of ovine corticotropin-releasing factor immunoreactive cells and fibers in the rat brain: an immunohistochemical study. Neuroendocrinology 36:165-186.
437. Tatemoto K. 1982. Isolation and characterization of peptide YY (PYY), a candidate gut hormone that inhibits pancreatic exocrine secretion. Proc Natl Acad Sci USA 79:2514-2518.
438. Tatemoto K, Carlquist M, Mutt V. 1982. Neuropeptide Y-a novel brain peptide with structural similarities to peptide YY and pancreatic polypeptide. Nature 296:659-660.
439. Tatum A, Seevers M, Collins K. 1929. Morphine addiction and its physiological interpretation based on experimental evidence. J Pharmacol Exp Ther 36:477-510.
440. Tetel MJ, Celentano DC, Blaustein JD. 1994. Intraneuronal convergence of tactile and hormonal stimuli associated with female reproduction in rats. J Neuroendocrinol 6:211-216.
441. Tetel MJ, Getzinger MJ, Blaustein JD. 1993. Fos expression in the rat brain following vaginal-cervical stimulation by mating and manual probing. J Neuroendocrinol 5:397-404.
442. Thody AJ, Wilson CA. 1983. Melanocyte stimulating hormone and the inhibition of sexual behaviour in the female rat. Physiol Behav 31:67-72.
443. Thompson RC, Mansour A, Akil H, Watson SJ. 1993. Cloning and Pharmacological Characterization of a Rat Mu-Opioid Receptor. Neuron 11:903-913.
444. Torii M, Kubo K. 1994. The effects of intraventricular injection of beta-endorphin on initial estrogen action to induce lordosis behavior. Physiol Behav 55:157-162.
445. Torii M, Kubo K, Sasaki T. 1995. Naloxone and initial estrogen action to induce lordosis in ovariectomized rats: the effect of a cut between the septum and preoptic area. Neurosci Lett 195:167-170.
446. Torii M, Kubo K, Sasaki T. 1996. Influence of opioid peptides on the priming action of estrogen on lordosis in ovariectomized rats. Neurosci Lett 212:68-70.
447. Torii M, Kubo K, Sasaki T. 1997. Differential effects of betaendorphin and Met- and Leu-enkephalin on steroid hormone-induced lordosis in ovariectomized female rats. Pharmacol Biochem Behav 58:837-842.
448. Torii M, Kubo K, Sasaki T. 1999. Facilitatory and inhibitory effects of beta-endorphin on lordosis in female rats: relation to time of administration. Horm Behav 35:271-278.
449. Uhler M, Herbert E, D'Eustachio P, Ruddle FD. 1983. The mouse genome contains two nonallelic pro-opiomelanocortin genes. J Biol Chem 258:9444-9453.
450. Ulibarri C, Micevych PE. 1993. Role of perinatal estrogens in sexual differentiation of the inhibition of lordosis by exogenous cholecystokinin. Physiol Behav 54:95-100.
451. Uphouse L. 2000. Female gonadal hormones, serotonin, and sexual receptivity. Brain Res Brain Res Rev 33:242-257.
452. Uphouse L, Wolf A. 2004. WAY100635 and female rat lordosis behavior. Brain Res 1013:260-263.
453. Uphouse L, Caldarola-Pastuszka M, Montanez S. 1992. Intracerebral actions of the 5-HT1A agonists, 8-OH-DPAT and buspirone and of the 5-HT1A partial agonist/antagonist, NAN-190, on female sexual behavior. Neuropharmacology 31:969-981.
454. Uphouse L, Caldarola-Pastuszka M, Moore N. 1993. Inhibitory effects of the 5-HT1A agonists, 5-hydroxy- and 5-methoxy-(3-di-n-propylamino) chroman, on female lordosis behavior. Neuropharmacology 32:641-651.
455. Uphouse L, Salamanca S, Caldarola-Pastuszka M. 1991. Gender and estrous cycle differences in the response to the 5-HT1A agonist 8-OH-DPAT. Pharmacol Biochem Behav 40:901-906.
456. Uphouse L, Andrade M, Caldarola-Pastuszka M, Jackson A. 1996. 5-HT1A receptor antagonists and lordosis behavior. Neuropharmacology 35:489-495.
457. Vasudevan N, Kow LM, Pfaff DW. 2001. Early membrane estrogenic effects required for full expression of slower genomic actions in a nerve cell line. Proc Natl Acad Sci USA 98:12267-12271.
458. Vathy I, Etgen AM. 1988. Ovarian steroids and hypothalamic norepinephrine release: studies using in vivo brain microdialysis. Life Sci 43:1493-1499.
459. Vathy I, Plas van der J, Vincent PA, Etgen AM. 1991. Intracranial dialysis and microinfusion studies suggest that morphine acts in the ventromedial hypothalamus to inhibit female rat sexual behavior. Horm Behav 25:354-366.
460. Vesely DL. 1979. Testosterone and its precursors and metabolites enhance guanylate cyclase activity. Proc Natl Acad Sci USA 76:3491-3494.
461. Vesely DL, Hill DE. 1980. Estrogens and progesterone increase fetal and maternal guanylate cyclase activity. Endocrinology 107:2104-2109.
462. Vilaro MT, Palacios JM, Mengod G. 1990. Localization of m5 muscarinic receptor mRNA in rat brain examined by in situ hybridization histochemistry. Neurosci Lett 114:154-159.
463. Villablanca AC, Hanley MR. 1997. 17beta-estradiol stimulates substance P receptor gene expression. Mol Cell Endocrinol 135:109-117.
464. Wade GN, Lempicki RL, Panicker AK, Frisbee RM, Blaustein JD. 1997. Leptin facilitates and inhibits sexual behavior in female hamsters. Am J Physiol 272:R1354-1358.
465. Wagner EJ, Ronnekleiv OK, Grandy DK, Kelly MJ. 1998. The peptide orphanin FQ inhibits beta-endorphin neurons and neurosecretory cells in the hypothalamic arcuate nucleus by activating an inwardly-rectifying K+ conductance. Neuroendocrinology 67:73-82.
466. Waldhoer M, Bartlett SE, Whistler JL. 2004. Opioid receptors. Annu Rev Biochem 73:953-990.
467. Wall SJ, Yasuda RP, Li M, Wolfe BB. 1991. Development of an antiserum against m3 muscarinic receptors: distribution of m3 receptors in rat tissues and clonal cell lines. Mol Pharmacol 40:783-789.
468. Wang JB, Johnson PS, Imai Y, Persico AM, Ozenberger BA, et al. 1994a. cDNA cloning of an orphan opiate receptor gene family member and its splice variant. FEBS Lett 348:75-79.
469. Wang JB, Johnson PS, Persico AM, Hawkins AL, Griffin CA, et al. 1994b. Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. FEBS Lett 338:217-222.
470. Weaver DR, Clemens LG. 1987. Nicotinic cholinergic influences on sexual receptivity in female rats. Pharmacol Biochem Behav 26:393-400.
471. White S, Uphouse L. 2004. Estrogen and progesterone dosedependently reduce disruptive effects of restraint on lordosis behavior. Horm Behav 45:201-208.
472. Wiesner JB, Moss. 1984. Beta-endorphin suppression of lordosis behavior lack of effect of peripherally-administered naloxone. Life Sci 34:1455-1462.
473. Wikberg JE, Muceniece R, Mandrika I, Prusis P, Lindblom J, et al. 2000. New aspects on the melanocortins and their receptors. Pharmacol Res 42:393-420.
474. Williams GW, McGinnis MY, Lumia AR. 1992. The effects of olfactory bulbectomy and chronic psychosocial stress on serum glucocorticoids and sexual behavior in female rats. Physiol Behav 52:755-760.
475. Wilson CA, Thody AJ, Hole DR, Grierson JP, Celis ME. 1991. Interaction of estradiol, alpha-melanocyte-stimulating hormone, and dopamine in the regulation of sexual receptivity in the female rat. Neuroendocrinology 54:14-22.
476. Wimalasena J, Meehan D, Dostal R, Foster JS, Cameron M, et al. 1993. Growth factors interact with estradiol and gonadotropins in the regulation of ovarian cancer cell growth and growth factor receptors. Oncol Res 5:325-337.
477. Witt DM, Insel TR. 1991. A selective oxytocin antagonist attenuates progesterone facilitation of female sexual behavior. Endocrinology 128:3269-3276.
478. Wolf A, Caldarola-Pastuszka M, Uphouse L. 1998a. Facilitation of female rat lordosis behavior by hypothalamic infusion of 5-HT (2A/2C) receptor agonists. Brain Res 779:84-95.
479. Wolf A, Caldarola-Pastuszka M, De Lashaw M, Uphouse L. 1999. 5-HT2C receptor involvement in female rat lordosis behavior. Brain Res 825:146-151.
480. Wolf A, Jackson A, Price T, Trevino A, Caldarola-Pastuszka M, et al. 1998b. Attenuation of the lordosis-inhibiting effects of 8-OH-DPAT by TFMPP and quipazine. Brain Res 804:206-211.
481. Wu TJ, Glucksman MJ, Roberts JL, Mani SK. 2006. Facilitation of Lordosis in Rats by a Metabolite of Luteinizing Hormone Releasing Hormone (LHRH). Endocrinology 147:2544-2549.
482. Wu TJ, Pierotti AR, Jakubowski M, Sheward WJ, Glucksman MJ, et al. 1997. Endopeptidase EC 3.4.24.15 presence in the rat median eminence and hypophysial portal blood and its modulation of the luteinizing hormone surge. J Neuroendocrinol 9:813-822.
483. Xing C, Yin Y, He X, Xie Z. 2006. Effects of insulin-like growth factor 1 on voltage-gated ion channels in cultured rat hippocampal neurons. Brain Res 1072:30-35.
484. Yamada Y, Nishida E. 1978. Effects of estrogen and adrenal androgen on unit activity of the rat brain. Brain Res 142:187-190.
485. Yang LY, Clemens LG. 1997. Function of intromissions on intromission-return latency of female rats during paced sexual behavior. Physiol Behav 61:889-894.
486. Yu WH, Walczewska A, Karanth S, McCann SM. 1997. Nitric oxide mediates leptin-induced luteinizing hormonereleasing hormone (LHRH) and LHRH and leptin-induced LH release from the pituitary gland. Endocrinology 138:5055-5058.
487. Zapf J, Hauri C, Futo E, Hussain M, Rutishauser J, et al. 1995. Intravenously injected insulin-like growth factor (IGF) I/IGF binding protein-3 complex exerts insulin-like effects in hypophysectomized, but not in normal rats. J Clin Invest 95:179-186.
488. Zhang Y, Lu L, Furlonger C, Wu GE, Paige CJ. 2000. Hemokinin is a hematopoietic-specific tachykinin that regulates B lymphopoiesis. Nat Immunol 1:392-397.
489. Zoli M, Agnati LF, Tinner B, Steinbusch HW, Fuxe K. 1993. Distribution of dopamine-immunoreactive neurons and their relationships to transmitter and hypothalamic hormone-immunoreactive neuronal systems in the rat mediobasal hypothalamus. A morphometric and microdensitometric analysis. J Chem Neuroanat 6:293-310.
490. Zubieta JK, Frey KA. 1993. Autoradiographic mapping of M3 muscarinic receptors in the rat brain. J Pharmacol Exp Ther 264:415-422.