NGF, cyclic AMP, and phorbol esters regulate oxytocin receptor gene transcription in SK-N-SH and MCF7 cells

Molecular Brain Research

Volumn 53, Issue 1-2, 1998, Pages 130-137

  Bale, Tracy L ^a   Dorsa, Daniel M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Forskolin; MCF7; Oxytocin receptor; Phorbol 12 myristate 13 acetate; Promoter; SK N SH; Transfection

Indexed keywords

ARGIPRESTOCIN; CYCLIC AMP; FORSKOLIN; NERVE GROWTH FACTOR; OXYTOCIN RECEPTOR; PHORBOL 13 ACETATE 12 MYRISTATE;

ARTICLE; CONTROLLED STUDY; DNA FLANKING REGION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MOLECULAR CLONING; PRIORITY JOURNAL;

ANIMALS; BRAIN; BREAST NEOPLASMS; CLONING, MOLECULAR; CYCLIC AMP; DNA-BINDING PROTEINS; FEMALE; FORSKOLIN; HUMANS; NERVE GROWTH FACTORS; NEUROBLASTOMA; PROMOTER REGIONS (GENETICS); RATS; RECEPTORS, OXYTOCIN; RECOMBINANT FUSION PROTEINS; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0031884391     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00287-8     Document Type: Article

References (50)

1. Adan R.A.H., Van Leeuwen F.W., Sonnemans M.A.F., Brouns M., Hoffman G., Verbalis J.G., Burbach J.P.H. The rat oxytocin receptor in brain, pituitary, mammary gland and uterus: partial sequence and immunocytochemical localization. Endocrinology. 136:1995;4022-4028.
2. Aronica S.M., Kraus W.L., Katzenellenbogen B.S. Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc. Natl. Acad. Sci. 91:1994;8517-8521.
3. Azar C.G., Scavarda N.J., Reynolds C.P., Brodeur G.M. Multiple defects of the nerve growth factor receptor in human neuroblastomas. Cell Growth Differ. 1:1990;421-428.
4. Bale T.L., Dorsa D.M. Effects of testosterone and its metabolites on oxytocin receptor mRNA expression in the ventromedial hypothalamus in male rats. Endocrinology. 136:1995;5135-5138.
5. Bale T.L., Dorsa D.M. Sex differences in and effects of estrogen on oxytocin receptor mRNA expression in the ventromedial hypothalamus. Endocrinology. 136:1995;27-32.
6. Bale T.L., Dorsa D.M., Johnston C.A. Oxytocin receptor mRNA in the ventromedial hypothalamus during the estrous cycle. J. Neurosci. 15(7):1995;5058-5064.
7. Bale T.L., Dorsa D.M. Cloning, novel promoter sequence, and estrogen regulation of a rat oxytocin receptor gene. Endocrinology. 138:1997;1151-1158.
8. Benedetto M.T., DeCicco F., Rossiello F., Nicosia A.L., Lupi G., Dell'Acqua Oxytocin receptor in human fetal membranes at term and during labor. J. Steroid Biochem. 35:1990;205-208.
9. 3H-Oxytocin binding sites in the rat brain demonstrated by quantitative light microscopic autoradiography. Eur. J. Pharmacol. 102:1984;365-367.
10. Caldwell J.D., Prange A.F., Pedersen C.A. Oxytocin facilitates the sexual receptivity of estrogen-treated female rats. Neuropeptides. 7:1986;175-189.
11. Cassoni P., Sapino A., Negro F., Bussolati G. Oxytocin inhibits proliferation of human breast cancer cell lines. Virchows Arch. 425:1994;467-472.
12. Cassoni P., Sapino A., Papotti M., Bussolati G. Oxytocin and oxytocin-analogue F314 inhibit cell proliferation and tumor growth of rat and mouse mammary carcinomas. Int. J. Cancer. 66:1996;817-820.
13. Chen T.K., Smith L.M., Gebhardt D.K., Birrer M.J., Brown P.H. Activation and inhibition of the AP-1 complex in human breast cancer cells. Mol. Carcinogenesis. 15:1996;215-226.
14. Chiu R., Imagawa M., Imbra R.J., Bockoven J.R., Karin M. Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters. Nature. 329:1987;648-651.
15. DeKloet E., Rotteveel F., Voorhuis T., Terlou M. Topography of binding sites for neurohypophyseal hormones in rat brain. Eur. J. Pharmacol. 110:1985;113.
16. De Kloet E.R., Voorhuis D.A.M., Boschma Y., Elands J. Estradiol modulates density of putative 'oxytocin receptors' in discrete rat brain regions. Neuroendocrinology. 44:1986;415-421.
17. De Kloet E.R., Voorhuis D.A.M., Elands J. Estradiol induces oxytocin binding sites in rat hypothalamic ventromedial nucleus. Eur. J. Pharmacol. 118:1985;185-186.
18. Fahrbach S.E., Morrell J.I., Pfaff D.W. Possible role of endogenous oxytocin in estrogen-facilitated maternal behavior in rats. Neuroendocrinology. 40:1985;526-532.
19. Fischer-Colbrie R., Eskay R.L., Eiden L.E., Maas D. Transsynaptic regulation of galanin, neurotensin, and substance P in the adrenal medulla: combinatorial control by second-messenger signaling pathways. J. Neurochem. 59:1992;780-783.
20. Gaub M.P., Bellard M., Scheuer I., Chambon P., Sassone-Corsi P. Activation of the ovalbumin gene by the estrogen receptor involves the fos-jun complex. Cell. 63:1990;1267-1276.
21. Gu G., Rojo A.A., Zee M.C., Yu J., Simerly R.B. Hormonal regulation of CREB phosphorylation in the anteroventral periventricular nucleus. J. Neurosci. 16:1996;3035-3044.
22. Hinko A., Soloff M.S. Up-regulation of oxytocin receptors in rabbit amnion by adenosine 3′,5′-monophosphate. Endocrinology. 132:1993;126-132.
23. Hinko A., Soloff M.S. Up-regulation of oxytocin receptors in rabbit amnion by glucocorticoids: potentiation by cyclic adenosine 3′, 5′-monophosphate. Endocrinology. 133:1993;1511-1519.
24. Imagawa M., Chiu R., Karin M. Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP. Cell. 51:1987;251-260.
25. Inoue T., Kimura T., Azuma C., Inazawa J., Takemura M., Kikuchi T., Kubota Y., Ogita K., Saji F. Structural organization of the human oxytocin receptor gene. J. Biol. Chem. 269:1994;32451-32456.
26. Ito Y., Kobayashi T., Kimura T., Matsuura N., Wakasugi E., Takeda T., Shimano T., Kubota Y., Nobunaga T., Makino Y., Azuma C., Saji F., Monden M. Investigation of the oxytocin receptor expression in human breast cancer tissue using newly established monoclonal antibodies. Endocrinology. 137:1996;773-779.
27. Janet T., Ludecke G., Otten U., Unsicker K. Heterogeneity of human neuroblastoma cell lines in their proliferative responses to basic FGF, NGF, and EGF: correlation with expression of growth factors and growth factor receptors. J. Neurosci. Res. 40:1995;707-715.
28. Jeng Y.J., Hinko A., Soloff M.S. Effectors of cyclic adenosine 5′-monophosphate up-regulating-oxytocin receptors in rabbit amnion cells: isoproterenol, parathyroid hormone-related protein, and potentiation by cortisol. Biol. Reprod. 53:1995;1051-1056.
29. Johnson A.E., Coirini H., Insel T.R., McEwen B.S. The regulation of oxytocin receptor binding in the ventromedial hypothalamic nucleus by testosterone and its metabolites. Endocrinology. 128:1991;891-896.
30. Johnson A.E., Coirini H., McEwen B.S., Insel T.R. Testosterone modulates oxytocin receptor binding in the hypothalamus of castrated male rats. Neuroendocrinology. 50:1989;199-203.
31. Kimura T., Osamu T., Kensaku M., Brownstein M.J., Okayama H. Structure and expression of a human oxytocin receptor. Nature. 356:1992;526-529.
32. Kow L.M., Brown H.E., Pfaff D.W. Activation of protein kinase C in the hypothalamic ventromedial nucleus or the midbrain central gray facilitates lordosis. Brain Res. 660:1994;241-248.
33. Larcher A., Neculcea J., Breton C., Arslan A., Rozen F., Russo C., Zingg H.H. Oxytocin receptor gene expression in the rat uterus during pregnancy and the estrous cycle and in response to gonadal steroid treatment. Endocrinology. 136:1995;5350-5356.
34. Lee W., Mitchell P., Tjian R. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell. 49:1987;741-752.
35. McCarthy M.M., Kleopoulos S.P., Mobbs C.V., Pfaff D.W. Infusion of antisense oligodeoxynucleotides to the oxytocin receptor in the ventromedial hypothalamus reduces estrogen-induced sexual receptivity and oxytocin receptor binding in the female rat. Neuroendocrinology. 59:1994;432-440.
36. Mermod N., Williams T.J., Tjian R. Enhancer binding factors AP-4 and AP-1 act in concert to activate SV40 late transcription in vitro. Nature. 332:1988;557-561.
37. Pedersen C.A., Prange A.J. Jr. Induction of maternal behavior after intracerebroventricular administration of oxytocin. Proc. Natl. Acad. Sci. USA. 76:1979;6661-6665.
38. Rozen F., Russo C., Banville D., Zingg H.H. Structure, characterization, and expression of the rat oxytocin receptor gene. Proc. Natl. Acad. Sci. 92:1995;200-204.
39. Schumacher M., Coirini H., Frankfurt M., McEwen B.S. Localized actions of progesterone in hypothalamus involve oxytocin. Proc. Natl. Acad. Sci. USA. 86:1989;6798-6801.
40. Schumacher M., Coirini H., Johnson A.E., Flanagan L.M., Frankfurt M., Pfaff D.W., McEwen B.S. The oxytocin receptor: a target for steroid hormones. Reg. Pept. 45:1993;115-119.
41. M.S. Smith, Lactation. in: H.D. Patton, A.F. Fuchs, B. Hille, A.M. Scher, R.S. Steiner (Eds.), Textbook of Physiology, Vol. 2, Saunders, Philadelphia, PA, 1989, pp. 1408-1421.
42. Stevenson K.R., Riley P.R., Stewart H.J., Flint A.P., Wathes D.C. Localization of oxytocin receptor mRNA in the ovine uterus during the oestrous cycle and early pregnancy. J. Mol. Endocrinol. 12:1994;93-105.
43. Taylor A.H., Ang V.Y.T., Jenkins J.S., Silverlight J.J., Coombes R.C., Lqumani Y.A. Interaction of vasopressin and oxytocin with human breast carcinoma cells. Cancer Res. 50:1990;7882-7886.
44. Tribollet E., Audiger S., Dubois-Dauphin M., Dreifuss J.J. Gonadal steroids regulate oxytocin receptors but not vasopressin receptors in the brain of male and female rats. An autoradiographic study. Brain Res. 511:1990;129-140.
45. Tribollet E., Barberis C., Jard S., Dubois-Dauphin M., Dreifuss J.J. Localization and pharmacological characterization of high affinity binding sites for vasopressin and oxytocin in the rat brain by light microscopic autoradiography. Brain Res. 442:1988;105-108.
46. Van Leengoed E., Kerker E., Swanson H.H. Inhibition of post-partum maternal behavior in the rat by injecting an oxytocin antagonist into cerebral ventricles. J. Endocrinol. 112:1987;275-282.
47. 3H-oxytocin binding sites in the rat brain, pituitary and mammary gland. Brain Res. 359:1985;320-325.
48. Wu W.X., Verbalis J.G., Hoffman G.E., Derks J.B., Nathanielsz P.W. Characterization of oxytocin receptor expression and distribution in the pregnant sheep uterus. Endocrinology. 137:1996;722-728.
49. Yoshimura M., Cooper D.M.F. Type-specific stimulation of adenylylcyclase by protein kinase C. J. Biol. Chem. 268:1993;4604-4607.
50. Zhou Y., Watters J.J., Dorsa D.M. Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain. Endocrinology. 137:1996;2163-2166.