μ-Opioid receptor mRNA expression in proopiomelanocortin neurons of the rat arcuate nucleus

Molecular Brain Research

Volumn 70, Issue 1, 1999, Pages 155-158

  Bouret, Sebastien ^a   Prevot, Vincent ^a   Croix, Dominique ^a   Jégou, Sylvie ^a   Vaudry, Hubert ^a   Stefano, George B ^b,c   Beauvillain, Jean Claude ^a   Mitchell, Valerie ^a  

^a INSERM   (France)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

Endorphin; Opioid receptor; Arcuate nucleus; Enkephalin; Proopiomelanocortin; Reproduction

Indexed keywords

BETA ENDORPHIN; ENKEPHALIN; MESSENGER RNA; MU OPIATE RECEPTOR; PROOPIOMELANOCORTIN;

ANIMAL TISSUE; ARCUATE NUCLEUS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IN SITU HYBRIDIZATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TECHNIQUE; TISSUE DISTRIBUTION;

ANIMALS; ARCUATE NUCLEUS; BETA-ENDORPHIN; DNA, COMPLEMENTARY; FEEDBACK; IN SITU HYBRIDIZATION; NERVE TISSUE PROTEINS; NEURONS; PRO-OPIOMELANOCORTIN; RATS; RECEPTORS, OPIOID, MU; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER;

EID: 0033064348     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(99)00132-1     Document Type: Article

References (26)

1. Blasquez C., Jegou S., Feuilloley M., Rosier A., Vandesande F., Vaudry H. Visualization of gamma-aminobutyric acid A receptors on proopiomelanocortin-producing neurons in the rat hypothalamus. Endocrinology. 135:1994;2759-2764.
2. Bianchi E., Alessandrini C., Guarna M., Tagliamonte A. Endogenous codeine and morphine are stored in specific brain neurons. Brain Res. 627:1993;210-215.
3. Bianchi E., Guarna M., Tagliamonte A. Immunocytochemical localization of endogenous codeine and morphine. Adv. Neuroimmunol. 4:1994;83-92.
4. Bouret S., Prevot V., Howard A.D., Habert-Ortoli E., Jegou S., Vaudry H., Vermersch P., Beauvillain J.C., Mitchell V. Differential coexpression of galanin receptor (GalR1, GalR2) and proopiomelanocortin (POMC) mRNAs in the rat arcuate nucleus. Soc. Neurosci. Abstr. 24:1998;1609.
5. Broberger C., Landry M., Wong H., Walsh J.N., Hökfelt T. Subtypes Y1 and Y2 of the neuropeptide Y receptor are, respectively, expressed in proopiomelanocortin- and neuropeptide-Y-containing neurons of the rat hypothalamic arcuate nucleus. Neuroendocrinology. 66:1997;393-408.
6. Bronstein D.M., Przewlocki R., Akil H. Effects of morphine treatment on proopiomelanocortin systems in rat brain. Brain Res. 519:1990;102-111.
7. Buckingham J.C. Stimulation and inhibition of corticotrophin releasing factor secretion by beta endorphin. Neuroendocrinology. 42:1986;148-152.
8. Ceccatelli S., Eriksson M., Hökfelt T. Distribution and coexistence of corticotropin-releasing factor-, neurotensin-, enkephalin-, cholecystokinin-, galanin- and vasoactive intestinal polypeptide/peptide histidine isoleucine-like peptides in the parvocellular part of the paraventricular nucleus. Neuroendocrinology. 49:1989;309-323.
9. Chen Y.Y., Pelletier G. Demonstration of contacts between proopiomelanocortin neurons in the rat hypothalamus. Neurosci. Lett. 43:1983;271-276.
10. Cheung C.C., Clifton D.K., Steiner R.A. Proopiomelanocortin neurons are direct targets for leptin in the hypothalamus. Endocrinology. 138:1997;4489-4492.
11. Cheung S., Hammer R.P. Gonadal steroid hormone regulation of proopiomelanocortin gene expression in arcuate neurons that innervate the medial preoptic area of the rat. Neuroendocrinology. 62:1995;283-292.
12. Finley J.C., Lindstrom P., Petrusz P. Immunocytochemical localization of beta-endorphin-containing neurons in the rat brain. Neuroendocrinology. 33:1981;28-42.
13. Garcia de Yebenes E., Pelletier G. Opioid regulation of proopiomelanocortin (POMC) gene expression in the rat brain as studied by in situ hybridization. Neuropeptides. 25:1993;91-94.
14. Hisano S., Daikoku S., Yanaihara N., Shibasaki T. Intragranular colocalization of CRF and Met-Enk-8 in nerve terminals in the rat median eminence. Brain Res. 370:1986;321-326.
15. Hökfelt T., Fahrenkrug J., Tatemoto K., Mutt V., Werner S., Hulting A.L., Terenius L., Chang K.J. The PHI (PHI-27)/corticotropin-releasing factor/enkephalin immunoreactive hypothalamic. neuron: possible morphological basis for integrated control of prolactin, corticotropin, and growth hormone secretion. Proc. Natl. Acad. Sci. USA. 80:1983;895-898.
16. Kelly M.J., Loose M.D., Ronnekleiv O.K. Opioids hyperpolarize beta-endorphin neurons via mu-receptor activation of a potassium conductance. Neuroendocrinology. 52:1990;268-275.
17. Kiss J.Z., Williams T.H. ACTH-immunoreactive boutons form synaptic contacts in the hypothalamic arcuate nucleus of rat: evidence for local opiocortin connections. Brain Res. 263:1983;142-146.
18. Mansour A., Fox C.A., Burke S., Meng F., Thompson R.C., Akil H., Watson S.J. Mu, delta, and kappa opioid receptor mRNA expression in the rat CNS: an in situ hybridization study. J. Comp. Neurol. 350:1994;412-438.
19. Mitchell V., Prevot V., Beauvillain J.C. Distribution and diurnal variations of the mu opioid receptor expression in the arcuate nucleus of the male rat. Neuroendocrinology. 67:1998;94-100.
20. Mitchell V., Prevot V., Jennes L., Aubert J.P., Croix D., Beauvillain J.C. Presence of mu and kappa opioid receptor mRNAs in galanin but not in GnRH neurons in the female rat. NeuroReport. 8:1997;3167-3172.
21. G. Paxinos, C. Watson, The Rat Brain in Stereotaxic Coordinates, 2nd edn., Academic Press, Sidney, 1986.
22. Stefano G.B., Scharrer B. Endogenous morphine and related opiates, a new class of chemical messengers. Adv. Neuroimmunol. 4:1994;57-67.
23. Stefano G.B., Scharrer B., Smith E.M., Hughes T.K. Jr., Magazine H.I., Bilfinger T.V., Hartman A.R., Fricchione G.L., Liu Y., Makman M.H. Opioid and opiate immunoregulatory processes. Crit. Rev. Immunol. 16:1996;109-144.
24. Wardlaw S.L., Kim J., Sobieszczyk S. Effect of morphine on proopiomelanocortin gene expression and peptide levels in the hypothalamus. Mol. Brain Res. 41:1996;140-147.
25. Wilcox J.N., Roberts J.L. Estrogen decreases rat hypothalamic proopiomelanocortin messenger ribonucleic acid levels. Endocrinology. 117:1985;2392-2396.
26. Zhang R., Hisano S., Chikamori-Aoyama M., Daikoku S. Synaptic association between enkephalin-containing axon terminals and proopiomelanocortin-containing neurons in the arcuate nucleus of rat hypothalamus. Neurosci. Lett. 82:1987;151-156.