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Volumn 28, Issue 3, 2013, Pages 172-189

Transduction of voltage and Ca2+ signals by Slo1 BK channels

Author keywords

[No Author keywords available]

Indexed keywords

KCNMA1 PROTEIN, HUMAN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL ALPHA SUBUNIT; PROTEIN BINDING;

EID: 84878598078     PISSN: 15489213     EISSN: 15489221     Source Type: Journal    
DOI: 10.1152/physiol.00055.2012     Document Type: Review
Times cited : (68)

References (197)
  • 2
    • 84455162079 scopus 로고    scopus 로고
    • The LRRC26 protein selectively alters the efficacy of BK channel activators
    • Almassy J, Begenisich T. The LRRC26 protein selectively alters the efficacy of BK channel activators. Mol Pharmacol 81: 21-30, 2012.
    • (2012) Mol Pharmacol , vol.81 , pp. 21-30
    • Almassy, J.1    Begenisich, T.2
  • 3
    • 0026395174 scopus 로고
    • Alcohol intoxication results in rapid loss in free magnesium in brain and disturbances in brain bioenergetics: Relation to cerebrovasospasm, alcoholinduced strokes, and barbiturate anesthesia-induced deaths
    • Altura BM, Altura BT, Gupta RK. Alcohol intoxication results in rapid loss in free magnesium in brain and disturbances in brain bioenergetics: relation to cerebrovasospasm, alcoholinduced strokes, and barbiturate anesthesia-induced deaths. Magnes Trace Elem 10: 122-135, 1991.
    • (1991) Magnes Trace Elem , vol.10 , pp. 122-135
    • Altura, B.M.1    Altura, B.T.2    Gupta, R.K.3
  • 4
    • 0027760983 scopus 로고
    • Ethanol promotes rapid depletion of intracellular free Mg in cerebral vascular smooth muscle cells: Possible relation to alcohol-induced behavioral and stroke-like effects
    • Altura BM, Zhang A, Cheng TP, Altura BT. Ethanol promotes rapid depletion of intracellular free Mg in cerebral vascular smooth muscle cells: possible relation to alcohol-induced behavioral and stroke-like effects. Alcohol 10: 563-566, 1993.
    • (1993) Alcohol , vol.10 , pp. 563-566
    • Altura, B.M.1    Zhang, A.2    Cheng, T.P.3    Altura, B.T.4
  • 6
    • 0037623283 scopus 로고    scopus 로고
    • Stimulatory action of internal protons on Slo1 BK channels
    • Avdonin V, Tang XD, Hoshi T. Stimulatory action of internal protons on Slo1 BK channels. Biophys J 84: 2969-2980, 2003.
    • (2003) Biophys J , vol.84 , pp. 2969-2980
    • Avdonin, V.1    Tang, X.D.2    Hoshi, T.3
  • 7
    • 25444519458 scopus 로고    scopus 로고
    • 2+ sensitivity is enhanced by its β1 subunit
    • 2+ sensitivity is enhanced by its β1 subunit. J Gen Physiol 126: 393-412, 2005.
    • (2005) J Gen Physiol , vol.126 , pp. 393-412
    • Bao, L.1    Cox, D.H.2
  • 10
    • 0020000206 scopus 로고
    • Properties of single calcium-activated potassium channels in cultured rat muscle
    • Barrett JN, Magleby KL, Pallotta BS. Properties of single calcium-activated potassium channels in cultured rat muscle. J Physiol 1982: 211-230, 1982.
    • (1982) J Physiol , vol.1982 , pp. 211-230
    • Barrett, J.N.1    Magleby, K.L.2    Pallotta, B.S.3
  • 11
    • 0034717111 scopus 로고    scopus 로고
    • hKCNMB3 and hKCNMB4, cloning and characterization of two members of the large-conductance calciumactivated potassium channel β subunit family
    • Behrens R, Nolting A, Reimann F, Schwarz M, Waldschutz R, Pongs O. hKCNMB3 and hKCNMB4, cloning and characterization of two members of the large-conductance calciumactivated potassium channel β subunit family. FEBS Lett 474: 99-106, 2000.
    • (2000) FEBS Lett , vol.474 , pp. 99-106
    • Behrens, R.1    Nolting, A.2    Reimann, F.3    Schwarz, M.4    Waldschutz, R.5    Pongs, O.6
  • 14
    • 41149095488 scopus 로고    scopus 로고
    • How membrane proteins sense voltage
    • Bezanilla F. How membrane proteins sense voltage. Nat Rev Mol Cell Biol 9: 323-332, 2008.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 323-332
    • Bezanilla, F.1
  • 16
    • 28044450874 scopus 로고    scopus 로고
    • BK channel β4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures
    • Brenner R, Chen QH, Vilaythong A, Toney GM, Noebels JL, Aldrich RW. BK channel β4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nat Neurosci 8: 1752-1759, 2005.
    • (2005) Nat Neurosci , vol.8 , pp. 1752-1759
    • Brenner, R.1    Chen, Q.H.2    Vilaythong, A.3    Toney, G.M.4    Noebels, J.L.5    Aldrich, R.W.6
  • 17
    • 0034009387 scopus 로고    scopus 로고
    • Cloning and functional characterization of novel large conductance calcium-activated potassium channel β subunits, hKCNMB3 and hKCNMB4
    • Brenner R, Jegla TJ, Wickenden A, Liu Y, Aldrich RW. Cloning and functional characterization of novel large conductance calcium-activated potassium channel β subunits, hKCNMB3 and hKCNMB4. J Biol Chem 275: 6453-6461, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 6453-6461
    • Brenner, R.1    Jegla, T.J.2    Wickenden, A.3    Liu, Y.4    Aldrich, R.W.5
  • 19
    • 34347222939 scopus 로고    scopus 로고
    • Kinetic relationship between the voltage sensor and the activation gate in spHCN channels
    • Bruening-Wright A, Elinder F, Larsson HP. Kinetic relationship between the voltage sensor and the activation gate in spHCN channels. J Gen Physiol 130: 71-81, 2007.
    • (2007) J Gen Physiol , vol.130 , pp. 71-81
    • Bruening-Wright, A.1    Elinder, F.2    Larsson, H.P.3
  • 20
    • 0030840167 scopus 로고    scopus 로고
    • + channel with fluorescence
    • + channel with fluorescence. Neuron 19: 1127-1140, 1997.
    • (1997) Neuron , vol.19 , pp. 1127-1140
    • Cha, A.1    Bezanilla, F.2
  • 21
    • 38749112951 scopus 로고    scopus 로고
    • A common pathway for charge transport through voltage-sensing domains
    • Chanda B, Bezanilla F. A common pathway for charge transport through voltage-sensing domains. Neuron 57: 345-351, 2008.
    • (2008) Neuron , vol.57 , pp. 345-351
    • Chanda, B.1    Bezanilla, F.2
  • 23
    • 84855495074 scopus 로고    scopus 로고
    • 2+ binding to open and closed states can activate BK channels provided that the voltage sensors are elevated
    • 2+ binding to open and closed states can activate BK channels provided that the voltage sensors are elevated. J Gen Physiol 138: 593-607, 2011.
    • (2011) J Gen Physiol , vol.138 , pp. 593-607
    • Chen, R.S.1    Geng, Y.2    Magleby, K.L.3
  • 24
    • 79961119376 scopus 로고    scopus 로고
    • Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating
    • Chen X, Aldrich RW. Charge substitution for a deep-pore residue reveals structural dynamics during BK channel gating. J Gen Physiol 138: 137-154, 2011.
    • (2011) J Gen Physiol , vol.138 , pp. 137-154
    • Chen, X.1    Aldrich, R.W.2
  • 25
    • 84872226412 scopus 로고    scopus 로고
    • Free-energy relationships in ion channels activated by voltage and ligand
    • Chowdhury S, Chanda B. Free-energy relationships in ion channels activated by voltage and ligand. J Gen Physiol 141: 11-28, 2013.
    • (2013) J Gen Physiol , vol.141 , pp. 11-28
    • Chowdhury, S.1    Chanda, B.2
  • 33
    • 35648948416 scopus 로고    scopus 로고
    • Vascular large conductance calcium-activated potassium channels: Functional role and therapeutic potential
    • Eichhorn B, Dobrev D. Vascular large conductance calcium-activated potassium channels: functional role and therapeutic potential. Naunyn Schmiedebergs Arch Pharmacol 376: 145-155, 2007.
    • (2007) Naunyn Schmiedebergs Arch Pharmacol , vol.376 , pp. 145-155
    • Eichhorn, B.1    Dobrev, D.2
  • 35
    • 0034977038 scopus 로고    scopus 로고
    • Conformational changes in S6 coupled to the opening of cyclic nucleotidegated channels
    • Flynn GE, Zagotta WN. Conformational changes in S6 coupled to the opening of cyclic nucleotidegated channels. Neuron 30: 689-698, 2001.
    • (2001) Neuron , vol.30 , pp. 689-698
    • Flynn, G.E.1    Zagotta, W.N.2
  • 36
    • 67349260120 scopus 로고    scopus 로고
    • Convergent evolution of alternative splices at domain boundaries of the BK channel
    • Fodor AA, Aldrich RW. Convergent evolution of alternative splices at domain boundaries of the BK channel. Annu Rev Physiol 71: 19-36, 2009.
    • (2009) Annu Rev Physiol , vol.71 , pp. 19-36
    • Fodor, A.A.1    Aldrich, R.W.2
  • 37
    • 33744478372 scopus 로고    scopus 로고
    • Statistical limits to the identification of ion channel domains by sequence similarity
    • Fodor AA, Aldrich RW. Statistical limits to the identification of ion channel domains by sequence similarity. J Gen Physiol 127: 755-766, 2006.
    • (2006) J Gen Physiol , vol.127 , pp. 755-766
    • Fodor, A.A.1    Aldrich, R.W.2
  • 40
    • 84855502011 scopus 로고    scopus 로고
    • Intragenic alternative splicing coordination is essential for Caenorhabditis elegans slo-1 gene function
    • Glauser DA, Johnson BE, Aldrich RW, Goodman MB. Intragenic alternative splicing coordination is essential for Caenorhabditis elegans slo-1 gene function. Proc Natl Acad Sci USA 108: 20790-20795, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 20790-20795
    • Glauser, D.A.1    Johnson, B.E.2    Aldrich, R.W.3    Goodman, M.B.4
  • 42
    • 84860510422 scopus 로고    scopus 로고
    • Stereospecific binding of a disordered peptide segment mediates BK channel inactivation
    • Gonzalez-Perez V, Zeng XH, Henzler-Wildman K, Lingle CJ. Stereospecific binding of a disordered peptide segment mediates BK channel inactivation. Nature 485: 133-136, 2012.
    • (2012) Nature , vol.485 , pp. 133-136
    • Gonzalez-Perez, V.1    Zeng, X.H.2    Henzler-Wildman, K.3    Lingle, C.J.4
  • 43
    • 78049482361 scopus 로고    scopus 로고
    • BK channels and a new form of hypertension
    • Grimm PR, Sansom SC. BK channels and a new form of hypertension. Kidney Int: 956-962, 2010.
    • (2010) Kidney Int , pp. 956-962
    • Grimm, P.R.1    Sansom, S.C.2
  • 44
    • 0034677524 scopus 로고    scopus 로고
    • Mapping the conformational wave of acetylcholine receptor channel gating
    • Grosman C, Zhou M, Auerbach A. Mapping the conformational wave of acetylcholine receptor channel gating. Nature 403: 773-776, 2000.
    • (2000) Nature , vol.403 , pp. 773-776
    • Grosman, C.1    Zhou, M.2    Auerbach, A.3
  • 46
    • 84862970522 scopus 로고    scopus 로고
    • An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate
    • Gruslova A, Semenov I, Wang B. An extracellular domain of the accessory β1 subunit is required for modulating BK channel voltage sensor and gate. J Gen Physiol 139: 57-67, 2011.
    • (2011) J Gen Physiol , vol.139 , pp. 57-67
    • Gruslova, A.1    Semenov, I.2    Wang, B.3
  • 47
    • 34249860846 scopus 로고    scopus 로고
    • BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells
    • Gu N, Vervaeke K, Storm JF. BK potassium channels facilitate high-frequency firing and cause early spike frequency adaptation in rat CA1 hippocampal pyramidal cells. J Physiol 580: 859-882, 2007.
    • (2007) J Physiol , vol.580 , pp. 859-882
    • Gu, N.1    Vervaeke, K.2    Storm, J.F.3
  • 48
    • 84863990918 scopus 로고    scopus 로고
    • GDNF induces mechanical hyperalgesia in muscle by reducing IBK in isolectin B4-positive nociceptors
    • Hendrich J, Alvarez P, Chen X, Levine JD. GDNF induces mechanical hyperalgesia in muscle by reducing IBK in isolectin B4-positive nociceptors. Neuroscience 219: 204-213, 2012.
    • (2012) Neuroscience , vol.219 , pp. 204-213
    • Hendrich, J.1    Alvarez, P.2    Chen, X.3    Levine, J.D.4
  • 50
    • 84871020411 scopus 로고    scopus 로고
    • Conformational coupling in BK potassium channels
    • Horrigan FT. Conformational coupling in BK potassium channels. J Gen Physiol 140: 625-634, 2012.
    • (2012) J Gen Physiol , vol.140 , pp. 625-634
    • Horrigan, F.T.1
  • 52
    • 0036714915 scopus 로고    scopus 로고
    • 2+ binding and channel opening in large conductance (BK) potassium channels
    • 2+ binding and channel opening in large conductance (BK) potassium channels. J Gen Physiol 120: 267-305, 2002.
    • (2002) J Gen Physiol , vol.120 , pp. 267-305
    • Horrigan, F.T.1    Aldrich, R.W.2
  • 54
    • 22244438901 scopus 로고    scopus 로고
    • Heme regulates allosteric activation of the Slo1 BK channel
    • Horrigan FT, Heinemann SH, Hoshi T. Heme regulates allosteric activation of the Slo1 BK channel. J Gen Physiol 126: 7-21, 2005.
    • (2005) J Gen Physiol , vol.126 , pp. 7-21
    • Horrigan, F.T.1    Heinemann, S.H.2    Hoshi, T.3
  • 55
    • 38049002536 scopus 로고    scopus 로고
    • 2+ enhances voltage sensor/ gate coupling in BK channels
    • 2+ enhances voltage sensor/ gate coupling in BK channels. J Gen Physiol 131: 13-32, 2008.
    • (2008) J Gen Physiol , vol.131 , pp. 13-32
    • Horrigan, F.T.1    Ma, Z.2
  • 63
    • 29844446588 scopus 로고    scopus 로고
    • Effects of multiple metal binding sites on calcium and magnesiumdependent activation of BK channels
    • Hu L, Yang H, Shi J, Cui J. Effects of multiple metal binding sites on calcium and magnesiumdependent activation of BK channels. J Gen Physiol 127: 35-50, 2006.
    • (2006) J Gen Physiol , vol.127 , pp. 35-50
    • Hu, L.1    Yang, H.2    Shi, J.3    Cui, J.4
  • 66
    • 0037198626 scopus 로고    scopus 로고
    • Crystal structure and mechanism of a calcium-gated potassium channel
    • Jiang Y, Lee A, Chen J, Cadene M, Chait BT, MacKinnon R. Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417: 515-522, 2002.
    • (2002) Nature , vol.417 , pp. 515-522
    • Jiang, Y.1    Lee, A.2    Chen, J.3    Cadene, M.4    Chait, B.T.5    McKinnon, R.6
  • 69
    • 2142859139 scopus 로고    scopus 로고
    • Calcium ion coordination: A comparison with that of beryllium, magnesium, and zinc
    • Katz AK, Glusker JP, Beebe SA, Bock CW. Calcium ion coordination: a comparison with that of beryllium, magnesium, and zinc. J Am Chem Soc 118: 5752-5763, 1996.
    • (1996) J Am Chem Soc , vol.118 , pp. 5752-5763
    • Katz, A.K.1    Glusker, J.P.2    Beebe, S.A.3    Bock, C.W.4
  • 70
    • 33646182618 scopus 로고    scopus 로고
    • β2 and β4 subunits of BK channels confer differential sensitivity to acute modulation by steroid hormones
    • King JT, Lovell PV, Rishniw M, Kotlikoff MI, Zeeman ML, McCobb DP. β2 and β4 subunits of BK channels confer differential sensitivity to acute modulation by steroid hormones. J Neurophysiol 95: 2878-2888, 2006.
    • (2006) J Neurophysiol , vol.95 , pp. 2878-2888
    • King, J.T.1    Lovell, P.V.2    Rishniw, M.3    Kotlikoff, M.I.4    Zeeman, M.L.5    McCobb, D.P.6
  • 71
    • 0035960010 scopus 로고    scopus 로고
    • cGMP-mediated facilitation in nerve terminals by enhancement of the spike afterhyperpolarization
    • Klyachko VA, Ahern GP, Jackson MB. cGMP-mediated facilitation in nerve terminals by enhancement of the spike afterhyperpolarization. Neuron 31: 1015-1025, 2001.
    • (2001) Neuron , vol.31 , pp. 1015-1025
    • Klyachko, V.A.1    Ahern, G.P.2    Jackson, M.B.3
  • 72
    • 0027964762 scopus 로고
    • + channel. Identification of the site of incorporation and implications for channel topology
    • + channel. Identification of the site of incorporation and implications for channel topology. J Biol Chem 269: 23336-23341, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 23336-23341
    • Knaus, H.G.1    Eberhart, A.2    Kaczorowski, G.J.3    Garcia, M.L.4
  • 73
    • 0028136565 scopus 로고
    • Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels
    • Knaus HG, Garcia-Calvo M, Kaczorowski GJ, Garcia ML. Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels. J Biol Chem 269: 3921-3924, 1994.
    • (1994) J Biol Chem , vol.269 , pp. 3921-3924
    • Knaus, H.G.1    Garcia-Calvo, M.2    Kaczorowski, G.J.3    Garcia, M.L.4
  • 74
    • 33847340188 scopus 로고    scopus 로고
    • A role for the S0 transmembrane segment in voltage-dependent gating of BK channels
    • Koval OM, Fan Y, Rothberg BS. A role for the S0 transmembrane segment in voltage-dependent gating of BK channels. J Gen Physiol 129: 209-220, 2007.
    • (2007) J Gen Physiol , vol.129 , pp. 209-220
    • Koval, O.M.1    Fan, Y.2    Rothberg, B.S.3
  • 75
    • 33645393241 scopus 로고    scopus 로고
    • Membrane proteins involved in potassium shifts during muscle activity and fatigue
    • Kristensen M, Hansen T, Juel C. Membrane proteins involved in potassium shifts during muscle activity and fatigue. Am J Physiol Regul Integr Comp Physiol 290: R766-R772, 2006.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Kristensen, M.1    Hansen, T.2    Juel, C.3
  • 76
    • 33745216690 scopus 로고    scopus 로고
    • A structural interpretation of voltage-gated potassium channel inactivation
    • Kurata HT, Fedida D. A structural interpretation of voltage-gated potassium channel inactivation. Prog Biophys Mol Biol 92: 185-208, 2006.
    • (2006) Prog Biophys Mol Biol , vol.92 , pp. 185-208
    • Kurata, H.T.1    Fedida, D.2
  • 77
    • 63849267426 scopus 로고    scopus 로고
    • β subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia
    • Lee US, Cui J. β subunit-specific modulations of BK channel function by a mutation associated with epilepsy and dyskinesia. J Physiol 587: 1481-1498, 2009.
    • (2009) J Physiol , vol.587 , pp. 1481-1498
    • Lee, U.S.1    Cui, J.2
  • 78
    • 78649728181 scopus 로고    scopus 로고
    • Modulation of BK channel gating by the β2 subunit involves both membrane-spanning and cytoplasmic domains of Slo1
    • Lee US, Shi J, Cui J. Modulation of BK channel gating by the β2 subunit involves both membrane-spanning and cytoplasmic domains of Slo1. J Neurosci 30: 16170-16179, 2010.
    • (2010) J Neurosci , vol.30 , pp. 16170-16179
    • Lee, U.S.1    Shi, J.2    Cui, J.3
  • 79
  • 82
    • 44349137529 scopus 로고    scopus 로고
    • Position and role of the BK channel alpha subunit S0 helix inferred from disulfide crosslinking
    • Liu G, Zakharov SI, Yang L, Deng SX, Landry DW, Karlin A, Marx SO. Position and role of the BK channel alpha subunit S0 helix inferred from disulfide crosslinking. J Gen Physiol 131: 537-548, 2008.
    • (2008) J Gen Physiol , vol.131 , pp. 537-548
    • Liu, G.1    Zakharov, S.I.2    Yang, L.3    Deng, S.X.4    Landry, D.W.5    Karlin, A.6    Marx, S.O.7
  • 83
    • 29444433657 scopus 로고    scopus 로고
    • CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels
    • Liu J, Asuncion-Chin M, Liu P, Dopico AM. CaM kinase II phosphorylation of slo Thr107 regulates activity and ethanol responses of BK channels. Nat Neurosci 9: 41-49, 2006.
    • (2006) Nat Neurosci , vol.9 , pp. 41-49
    • Liu, J.1    Asuncion-Chin, M.2    Liu, P.3    Dopico, A.M.4
  • 86
    • 33644610046 scopus 로고    scopus 로고
    • Role of charged residues in the S1-S4 voltage sensor of BK channels
    • Ma Z, Lou XJ, Horrigan FT. Role of charged residues in the S1-S4 voltage sensor of BK channels. J Gen Physiol 127: 309-328, 2006.
    • (2006) J Gen Physiol , vol.127 , pp. 309-328
    • Ma, Z.1    Lou, X.J.2    Horrigan, F.T.3
  • 87
    • 0020973066 scopus 로고
    • Calcium dependence of open and shut interval distributions from calcium-activated potassium channels in cultured rat muscle
    • Magleby KL, Pallotta BS. Calcium dependence of open and shut interval distributions from calcium-activated potassium channels in cultured rat muscle. J Physiol 344: 585-604, 1983.
    • (1983) J Physiol , vol.344 , pp. 585-604
    • Magleby, K.L.1    Pallotta, B.S.2
  • 88
    • 0032578634 scopus 로고    scopus 로고
    • 2+ channels in hippocampal neurons
    • 2+ channels in hippocampal neurons. Nature 395: 900-905, 1998.
    • (1998) Nature , vol.395 , pp. 900-905
    • Marrion, N.V.1    Tavalin, S.J.2
  • 90
    • 0028926916 scopus 로고
    • Functional role of the β subunit of high conductance calcium-activated potassium channels
    • McManus OB, Helms LM, Pallanck L, Ganetzky B, Swanson R, Leonard RJ. Functional role of the β subunit of high conductance calcium-activated potassium channels. Neuron 14: 645-650, 1995.
    • (1995) Neuron , vol.14 , pp. 645-650
    • McManus, O.B.1    Helms, L.M.2    Pallanck, L.3    Ganetzky, B.4    Swanson, R.5    Leonard, R.J.6
  • 91
  • 92
    • 0023734971 scopus 로고
    • Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle
    • McManus OB, Magleby KL. Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle. J Physiol 402: 79-120, 1988.
    • (1988) J Physiol , vol.402 , pp. 79-120
    • McManus, O.B.1    Magleby, K.L.2
  • 93
    • 0024806989 scopus 로고
    • Kinetic time constants independent of previous single-channel activity suggest Markov gating for a large conductance Ca-activated K channel
    • McManus OB, Magleby KL. Kinetic time constants independent of previous single-channel activity suggest Markov gating for a large conductance Ca-activated K channel. J Gen Physiol 94: 1037-1070, 1989.
    • (1989) J Gen Physiol , vol.94 , pp. 1037-1070
    • McManus, O.B.1    Magleby, K.L.2
  • 94
    • 0031457570 scopus 로고    scopus 로고
    • + channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus
    • + channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus. Proc Natl Acad Sci USA 94: 14066-14071, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 14066-14071
    • Meera, P.1    Wallner, M.2    Song, M.3    Toro, L.4
  • 97
    • 0020358450 scopus 로고
    • The gating of single calcium-dependent potassium channels is described by an activation/blockade mechanism
    • Methfessel C, Boheim G. The gating of single calcium-dependent potassium channels is described by an activation/blockade mechanism. Biophys Struct Mech 9: 35-60, 1982.
    • (1982) Biophys Struct Mech , vol.9 , pp. 35-60
    • Methfessel, C.1    Boheim, G.2
  • 98
    • 84864276601 scopus 로고    scopus 로고
    • The first transmembrane domain (TM1) of β2-subunit binds to the transmembrane domain S1 of α-subunit in BK potassium channels
    • Morera FJ, Alioua A, Kundu P, Salazar M, Gonzalez C, Martinez AD, Stefani E, Toro L, Latorre R. The first transmembrane domain (TM1) of β2-subunit binds to the transmembrane domain S1 of α-subunit in BK potassium channels. FEBS Lett 586: 2287-2293, 2012.
    • (2012) FEBS Lett , vol.586 , pp. 2287-2293
    • Morera, F.J.1    Alioua, A.2    Kundu, P.3    Salazar, M.4    Gonzalez, C.5    Martinez, A.D.6    Stefani, E.7    Toro, L.8    Latorre, R.9
  • 101
    • 48949117594 scopus 로고    scopus 로고
    • BK channel modulators: A comprehensive overview
    • Nardi A, Olesen SP. BK channel modulators: a comprehensive overview. Curr Med Chem 15: 1126-1146, 2008.
    • (2008) Curr Med Chem , vol.15 , pp. 1126-1146
    • Nardi, A.1    Olesen, S.P.2
  • 102
    • 85047694012 scopus 로고    scopus 로고
    • + channel protects against hypertension
    • + channel protects against hypertension. J Clin Invest 113: 955-957, 2004.
    • (2004) J Clin Invest , vol.113 , pp. 955-957
    • Nelson, M.T.1    Bonev, A.D.2
  • 104
    • 0033222872 scopus 로고    scopus 로고
    • Modular assembly of voltage-gated channel proteins: A sequence analysis and phylogenetic study
    • Nelson RD, Kuan G, Saier MH Jr, Montal M. Modular assembly of voltage-gated channel proteins: a sequence analysis and phylogenetic study. J Mol Microbiol Biotechnol 1: 281-287, 1999.
    • (1999) J Mol Microbiol Biotechnol , vol.1 , pp. 281-287
    • Nelson, R.D.1    Kuan, G.2    Saier Jr., M.H.3    Montal, M.4
  • 105
    • 0032948417 scopus 로고    scopus 로고
    • 2+-activated potassium channels by retaining the gating in the bursting states
    • 2+-activated potassium channels by retaining the gating in the bursting states. J Gen Physiol 113: 425-440, 1999.
    • (1999) J Gen Physiol , vol.113 , pp. 425-440
    • Nimigean, C.M.1    Magleby, K.L.2
  • 107
    • 17044420817 scopus 로고    scopus 로고
    • Differential effects of β1 and β2 subunits on BK channel activity
    • Orio P, Latorre R. Differential effects of β1 and β2 subunits on BK channel activity. J Gen Physiol 125: 395-411, 2005.
    • (2005) J Gen Physiol , vol.125 , pp. 395-411
    • Orio, P.1    Latorre, R.2
  • 109
    • 0022359527 scopus 로고
    • N-bromoacetamide removes a calcium-dependent component of channel opening from calcium-activated potassium channels in rat skeletal muscle
    • Pallotta BS. N-bromoacetamide removes a calcium-dependent component of channel opening from calcium-activated potassium channels in rat skeletal muscle. J Gen Physiol 86: 601-611, 1985.
    • (1985) J Gen Physiol , vol.86 , pp. 601-611
    • Pallotta, B.S.1
  • 112
    • 78650073828 scopus 로고    scopus 로고
    • Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BKCa channel
    • Pantazis A, Kohanteb AP, Olcese R. Relative motion of transmembrane segments S0 and S4 during voltage sensor activation in the human BKCa channel. J Gen Physiol 136: 645-657, 2010.
    • (2010) J Gen Physiol , vol.136 , pp. 645-657
    • Pantazis, A.1    Kohanteb, A.P.2    Olcese, R.3
  • 113
    • 84866161825 scopus 로고    scopus 로고
    • Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing
    • Pantazis A, Olcese R. Relative transmembrane segment rearrangements during BK channel activation resolved by structurally assigned fluorophore-quencher pairing. J Gen Physiol 140: 207-218, 2012.
    • (2012) J Gen Physiol , vol.140 , pp. 207-218
    • Pantazis, A.1    Olcese, R.2
  • 117
    • 0021269612 scopus 로고
    • Calcium-activated potassium channels and their role in secretion
    • Petersen OH, Maruyama Y. Calcium-activated potassium channels and their role in secretion. Nature 307: 693-696, 1984.
    • (1984) Nature , vol.307 , pp. 693-696
    • Petersen, O.H.1    Maruyama, Y.2
  • 120
    • 0024401693 scopus 로고
    • A family of calcium-dependent potassium channels from rat brain
    • Reinhart PH, Chung S, Levitan IB. A family of calcium-dependent potassium channels from rat brain. Neuron 2: 1031-1041, 1989.
    • (1989) Neuron , vol.2 , pp. 1031-1041
    • Reinhart, P.H.1    Chung, S.2    Levitan, I.B.3
  • 121
    • 3843128850 scopus 로고    scopus 로고
    • Allosteric modulation of ion channels: The case of maxi-K
    • Rothberg BS. Allosteric modulation of ion channels: the case of maxi-K. Sci STKE: pe16, 2004.
    • (2004) Sci STKE
    • Rothberg, B.S.1
  • 122
    • 0033067095 scopus 로고    scopus 로고
    • 2+ suggest a two-tiered allosteric gating mechanism
    • 2+ suggest a two-tiered allosteric gating mechanism. J Gen Physiol 114: 93-124, 1999.
    • (1999) J Gen Physiol , vol.114 , pp. 93-124
    • Rothberg, B.S.1    Magleby, K.L.2
  • 123
    • 0033623996 scopus 로고    scopus 로고
    • + channels described by a two-tiered allosteric gating mechanism
    • + channels described by a two-tiered allosteric gating mechanism. J Gen Physiol 116: 75-99, 2000.
    • (2000) J Gen Physiol , vol.116 , pp. 75-99
    • Rothberg, B.S.1    Magleby, K.L.2
  • 125
    • 80052632039 scopus 로고    scopus 로고
    • Identification and quantification of full-length BK channel variants in the developing mouse cochlea
    • Sakai Y, Harvey M, Sokolowski B. Identification and quantification of full-length BK channel variants in the developing mouse cochlea. J Neurosci Res 89: 1747-1760, 2011.
    • (2011) J Neurosci Res , vol.89 , pp. 1747-1760
    • Sakai, Y.1    Harvey, M.2    Sokolowski, B.3
  • 130
    • 84862698724 scopus 로고    scopus 로고
    • The contribution of RCK domains to human BK channel allosteric activation
    • Savalli N, Pantazis A, Yusifov T, Sigg D, Olcese R. The contribution of RCK domains to human BK channel allosteric activation. J Biol Chem 287: 21741-21750, 2012.
    • (2012) J Biol Chem , vol.287 , pp. 21741-21750
    • Savalli, N.1    Pantazis, A.2    Yusifov, T.3    Sigg, D.4    Olcese, R.5
  • 131
    • 0031952461 scopus 로고    scopus 로고
    • Activation of Shaker potassium channels III-an activation gating model for wild-type and V2 mutant channels
    • Schoppa NE, Sigworth FJ. Activation of Shaker potassium channels III-an activation gating model for wild-type and V2 mutant channels. J Gen Physiol 111: 313-342, 1998.
    • (1998) J Gen Physiol , vol.111 , pp. 313-342
    • Schoppa, N.E.1    Sigworth, F.J.2
  • 133
    • 0030852701 scopus 로고    scopus 로고
    • A novel calcium-sensing domain in the BK channel
    • Schreiber M, Salkoff L. A novel calcium-sensing domain in the BK channel. Biophys J 73: 1355-1363, 1997.
    • (1997) Biophys J , vol.73 , pp. 1355-1363
    • Schreiber, M.1    Salkoff, L.2
  • 135
    • 0035478635 scopus 로고    scopus 로고
    • Protein kinases: Tuners of the BKCa channel in smooth muscle
    • Schubert R, Nelson MT. Protein kinases: tuners of the BKCa channel in smooth muscle. Trends Pharmacol Sci 22: 505-512, 2001.
    • (2001) Trends Pharmacol Sci , vol.22 , pp. 505-512
    • Schubert, R.1    Nelson, M.T.2
  • 137
    • 0033571452 scopus 로고    scopus 로고
    • + channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells
    • + channels in spike broadening during repetitive firing in rat hippocampal pyramidal cells. J Physiol 521: 135-146, 1999.
    • (1999) J Physiol , vol.521 , pp. 135-146
    • Shao, L.R.1    Halvorsrud, R.2    Borg-Graham, L.3    Storm, J.F.4
  • 138
    • 0028178520 scopus 로고
    • Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: Evidence for tetrameric channel formation
    • Shen KZ, Lagrutta A, Davies NW, Standen NB, Adelman JP, North RA. Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: evidence for tetrameric channel formation. Pflügers Arch 426: 440-445, 1994.
    • (1994) Pflügers Arch , vol.426 , pp. 440-445
    • Shen, K.Z.1    Lagrutta, A.2    Davies, N.W.3    Standen, N.B.4    Adelman, J.P.5    North, R.A.6
  • 141
    • 0035445042 scopus 로고    scopus 로고
    • Alternative splicing of potassium channels: A dynamic switch of cellular excitability
    • Shipston MJ. Alternative splicing of potassium channels: a dynamic switch of cellular excitability. Trends Cell Biol 11: 353-358, 2001.
    • (2001) Trends Cell Biol , vol.11 , pp. 353-358
    • Shipston, M.J.1
  • 142
    • 84872222262 scopus 로고    scopus 로고
    • A linkage analysis toolkit for studying allosteric networks in ion channels
    • Sigg D. A linkage analysis toolkit for studying allosteric networks in ion channels. J Gen Physiol 141: 29-60, 2013.
    • (2013) J Gen Physiol , vol.141 , pp. 29-60
    • Sigg, D.1
  • 143
    • 0028363431 scopus 로고
    • + channels using two-dimensional dwell-time distributions
    • + channels using two-dimensional dwell-time distributions. Biophys J 67: 91-104, 1994.
    • (1994) Biophys J , vol.67 , pp. 91-104
    • Song, L.1    Magleby, K.L.2
  • 145
    • 57749196006 scopus 로고    scopus 로고
    • Sensing voltage across lipid membranes
    • Swartz KJ. Sensing voltage across lipid membranes. Nature 456: 891-897, 2008.
    • (2008) Nature , vol.456 , pp. 891-897
    • Swartz, K.J.1
  • 146
    • 59449101655 scopus 로고    scopus 로고
    • 2+ binding constants: Effects of membrane voltage
    • 2+ binding constants: effects of membrane voltage. J Gen Physiol 132: 491-505, 2008.
    • (2008) J Gen Physiol , vol.132 , pp. 491-505
    • Sweet, T.B.1    Cox, D.H.2
  • 147
    • 62349121072 scopus 로고    scopus 로고
    • 2+ binding to the BKCa channel
    • 2+ binding to the BKCa channel. J Gen Physiol 133: 139-150, 2009.
    • (2009) J Gen Physiol , vol.133 , pp. 139-150
    • Sweet, T.B.1    Cox, D.H.2
  • 148
    • 0030857866 scopus 로고    scopus 로고
    • Molecular constituents of maxi KCa channels in human coronary smooth muscle: Predominant α+β subunit complexes
    • Tanaka Y, Meera P, Song M, Knaus HG, Toro L. Molecular constituents of maxi KCa channels in human coronary smooth muscle: predominant α+β subunit complexes. J Physiol 502: 545-557, 1997.
    • (1997) J Physiol , vol.502 , pp. 545-557
    • Tanaka, Y.1    Meera, P.2    Song, M.3    Knaus, H.G.4    Toro, L.5
  • 150
  • 153
    • 28244483866 scopus 로고    scopus 로고
    • 2+-independent activation of BKCa channels at negative potentials in mammalian inner hair cells
    • 2+-independent activation of BKCa channels at negative potentials in mammalian inner hair cells. J Physiol 569: 137-151, 2005.
    • (2005) J Physiol , vol.569 , pp. 137-151
    • Thurm, H.1    Fakler, B.2    Oliver, D.3
  • 155
    • 26944481962 scopus 로고    scopus 로고
    • Phenotype-dependent functional and pharmacological properties of BK channels in skeletal muscle: Effects of microgravity
    • Tricarico D, Mele A, Conte Camerino D. Phenotype-dependent functional and pharmacological properties of BK channels in skeletal muscle: effects of microgravity. Neurobiol Dis 20: 296-302, 2005.
    • (2005) Neurobiol Dis , vol.20 , pp. 296-302
    • Tricarico, D.1    Mele, A.2    Conte Camerino, D.3
  • 157
    • 48749110968 scopus 로고    scopus 로고
    • Direct regulation of BK channels by phosphatidylinositol 4,5-bisphosphate as a novel signaling pathway
    • Vaithianathan T, Bukiya A, Liu J, Liu P, Asuncion-Chin M, Fan Z, Dopico A. Direct regulation of BK channels by phosphatidylinositol 4,5-bisphosphate as a novel signaling pathway. J Gen Physiol 132: 13-28, 2008.
    • (2008) J Gen Physiol , vol.132 , pp. 13-28
    • Vaithianathan, T.1    Bukiya, A.2    Liu, J.3    Liu, P.4    Asuncion-Chin, M.5    Fan, Z.6    Dopico, A.7
  • 159
    • 83355177269 scopus 로고    scopus 로고
    • In search of a consensus model of the resting state of a voltage-sensing domain
    • Vargas E, Bezanilla F, Roux B. In search of a consensus model of the resting state of a voltage-sensing domain. Neuron 72: 713-720, 2011.
    • (2011) Neuron , vol.72 , pp. 713-720
    • Vargas, E.1    Bezanilla, F.2    Roux, B.3
  • 160
    • 0029988261 scopus 로고    scopus 로고
    • + channels: An additional transmembrane region at the N terminus
    • + channels: an additional transmembrane region at the N terminus. Proc Natl Acad Sci USA 93: 14922-14927, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 14922-14927
    • Wallner, M.1    Meera, P.2    Toro, L.3
  • 162
    • 33645324028 scopus 로고    scopus 로고
    • Mechanism of β4 subunit modulation of BK channels
    • Wang B, Rothberg BS, Brenner R. Mechanism of β4 subunit modulation of BK channels. J Gen Physiol 127: 449-465, 2006.
    • (2006) J Gen Physiol , vol.127 , pp. 449-465
    • Wang, B.1    Rothberg, B.S.2    Brenner, R.3
  • 163
    • 70249124205 scopus 로고    scopus 로고
    • Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy
    • Wang L, Sigworth FJ. Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Nature 461: 292-295, 2009.
    • (2009) Nature , vol.461 , pp. 292-295
    • Wang, L.1    Sigworth, F.J.2
  • 166
    • 24944477440 scopus 로고    scopus 로고
    • Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel
    • Werner ME, Zvara P, Meredith AL, Aldrich RW, Nelson MT. Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel. J Physiol 567: 545-556, 2005.
    • (2005) J Physiol , vol.567 , pp. 545-556
    • Werner, M.E.1    Zvara, P.2    Meredith, A.L.3    Aldrich, R.W.4    Nelson, M.T.5
  • 167
    • 33748094494 scopus 로고    scopus 로고
    • State-independent block of BK channels by an intracellular quaternary ammonium
    • Wilkens CM, Aldrich RW. State-independent block of BK channels by an intracellular quaternary ammonium. J Gen Physiol 128: 347-364, 2006.
    • (2006) J Gen Physiol , vol.128 , pp. 347-364
    • Wilkens, C.M.1    Aldrich, R.W.2
  • 169
    • 84872234147 scopus 로고    scopus 로고
    • Positions of β2 and β3 subunits in the large-conductance calciumand voltage-activated BK potassium channel
    • Wu RS, Liu G, Zakharov SI, Chudasama N, Motoike H, Karlin A, Marx SO. Positions of β2 and β3 subunits in the large-conductance calciumand voltage-activated BK potassium channel. J Gen Physiol 141: 105-117, 2013.
    • (2013) J Gen Physiol , vol.141 , pp. 105-117
    • Wu, R.S.1    Liu, G.2    Zakharov, S.I.3    Chudasama, N.4    Motoike, H.5    Karlin, A.6    Marx, S.O.7
  • 170
    • 78049465933 scopus 로고    scopus 로고
    • The BK potassium channel in the vascular smooth muscle and kidney: α-and β-subunits
    • Wu RS, Marx SO. The BK potassium channel in the vascular smooth muscle and kidney: α-and β-subunits. Kidney Int 78: 963-974, 2010.
    • (2010) Kidney Int , vol.78 , pp. 963-974
    • Wu, R.S.1    Marx, S.O.2
  • 173
    • 0345298282 scopus 로고    scopus 로고
    • 2+-and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells
    • 2+-and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells. J Neurosci 19: 5255-5264, 1999.
    • (1999) J Neurosci , vol.19 , pp. 5255-5264
    • Xia, X.M.1    Ding, J.P.2    Lingle, C.J.3
  • 174
    • 0034234522 scopus 로고    scopus 로고
    • 2+-activated, voltage-dependent BK currents: Consequences of rapid inactivation by a novel β subunit
    • 2+-activated, voltage-dependent BK currents: consequences of rapid inactivation by a novel β subunit. J Neurosci 20: 4890-4903, 2000.
    • (2000) J Neurosci , vol.20 , pp. 4890-4903
    • Xia, X.M.1    Ding, J.P.2    Zeng, X.H.3    Duan, K.L.4    Lingle, C.J.5
  • 175
    • 0037158754 scopus 로고    scopus 로고
    • Multiple regulatory sites in large-conductance calcium-activated potassium channels
    • Xia XM, Zeng X, Lingle CJ. Multiple regulatory sites in large-conductance calcium-activated potassium channels. Nature 418: 880-884, 2002.
    • (2002) Nature , vol.418 , pp. 880-884
    • Xia, X.M.1    Zeng, X.2    Lingle, C.J.3
  • 176
    • 84861209847 scopus 로고    scopus 로고
    • BK potassium channel modulation by leucine-rich repeat-containing proteins
    • Yan J, Aldrich RW. BK potassium channel modulation by leucine-rich repeat-containing proteins. Proc Natl Acad Sci USA 109: 7917-7922, 2012.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 7917-7922
    • Yan, J.1    Aldrich, R.W.2
  • 177
    • 77954954506 scopus 로고    scopus 로고
    • LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium
    • Yan J, Aldrich RW. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 466: 513-516, 2010.
    • (2010) Nature , vol.466 , pp. 513-516
    • Yan, J.1    Aldrich, R.W.2
  • 178
    • 82755195901 scopus 로고    scopus 로고
    • LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel
    • Yang C, Zeng XH, Zhou Y, Xia XM, Lingle CJ. LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel. Proc Natl Acad Sci USA 108: 19419-19424, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 19419-19424
    • Yang, C.1    Zeng, X.H.2    Zhou, Y.3    Xia, X.M.4    Lingle, C.J.5
  • 179
    • 33749512771 scopus 로고    scopus 로고
    • Tuning magnesium sensitivity of BK channels by mutations
    • Yang H, Hu L, Shi J, Cui J. Tuning magnesium sensitivity of BK channels by mutations. Biophys J 91: 2892-2900, 2006.
    • (2006) Biophys J , vol.91 , pp. 2892-2900
    • Yang, H.1    Hu, L.2    Shi, J.3    Cui, J.4
  • 187
    • 0028140472 scopus 로고
    • Shaker potassium channel gating. III: Evaluation of kinetic models for activation
    • Zagotta WN, Hoshi T, Aldrich RW. Shaker potassium channel gating. III: Evaluation of kinetic models for activation. J Gen Physiol 103: 321-362, 1994.
    • (1994) J Gen Physiol , vol.103 , pp. 321-362
    • Zagotta, W.N.1    Hoshi, T.2    Aldrich, R.W.3
  • 188
    • 0034966691 scopus 로고    scopus 로고
    • Gating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH2-and COOH termini
    • Zeng XH, Ding JP, Xia XM, Lingle CJ. Gating properties conferred on BK channels by the beta3b auxiliary subunit in the absence of its NH2-and COOH termini. J Gen Physiol 117: 607-628, 2001.
    • (2001) J Gen Physiol , vol.117 , pp. 607-628
    • Zeng, X.H.1    Ding, J.P.2    Xia, X.M.3    Lingle, C.J.4
  • 189
    • 15244340463 scopus 로고    scopus 로고
    • Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites
    • Zeng XH, Xia XM, Lingle CJ. Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites. J Gen Physiol 125: 273-286, 2005.
    • (2005) J Gen Physiol , vol.125 , pp. 273-286
    • Zeng, X.H.1    Xia, X.M.2    Lingle, C.J.3
  • 191
    • 0035174487 scopus 로고    scopus 로고
    • 2+ through a nonselective, low affinity divalent cation site
    • 2+ through a nonselective, low affinity divalent cation site. J Gen Physiol 118: 607-635, 2001.
    • (2001) J Gen Physiol , vol.118 , pp. 607-635
    • Zhang, X.1    Solaro, C.R.2    Lingle, C.J.3
  • 192
    • 19344369189 scopus 로고    scopus 로고
    • Alteration of arterial smooth muscle potassium channel composition and BKCa current modulation in hypertension
    • Zhang Y, Gao YJ, Zuo J, Lee RM, Janssen LJ. Alteration of arterial smooth muscle potassium channel composition and BKCa current modulation in hypertension. Eur J Pharmacol 514: 111-119, 2005.
    • (2005) Eur J Pharmacol , vol.514 , pp. 111-119
    • Zhang, Y.1    Gao, Y.J.2    Zuo, J.3    Lee, R.M.4    Janssen, L.J.5
  • 193
    • 77956253696 scopus 로고    scopus 로고
    • Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells
    • Zhao G, Neeb ZP, Leo MD, Pachuau J, Adebiyi A, Ouyang K, Chen J, Jaggar JH. Type 1 IP3 receptors activate BKCa channels via local molecular coupling in arterial smooth muscle cells. J Gen Physiol 136: 283-291, 2010.
    • (2010) J Gen Physiol , vol.136 , pp. 283-291
    • Zhao, G.1    Neeb, Z.P.2    Leo, M.D.3    Pachuau, J.4    Adebiyi, A.5    Ouyang, K.6    Chen, J.7    Jaggar, J.H.8
  • 194
    • 79961055467 scopus 로고    scopus 로고
    • Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region
    • Zhou Y, Xia XM, Lingle CJ. Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region. Proc Natl Acad Sci USA 108: 12161-12166, 2011.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 12161-12166
    • Zhou, Y.1    Xia, X.M.2    Lingle, C.J.3
  • 197
    • 0028940921 scopus 로고
    • Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback
    • Zweifach A, Lewis RS. Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback. J Gen Physiol 105: 209-226, 1995.
    • (1995) J Gen Physiol , vol.105 , pp. 209-226
    • Zweifach, A.1    Lewis, R.S.2


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