Thromboxane A2 receptor and MaxiK-channel intimate interaction supports channel trans-inhibition independent of G-protein activation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 44, 2010, Pages 19096-19101

  Li, Min ^a   Tanaka, Yoshio ^b   Alioua, Abderrahmane ^a   Wu, Yong ^a   Lu, Rong ^a   Kundu, Pallob ^c   Sanchez Pastor, Enrique ^d   Marijic, Jure ^a   Stefani, Enrico ^a,e   Toro, Ligia ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TOHO UNIVERSITY   (Japan)

^c BOSE INSTITUTE   (India)

^d UNIVERSIDAD DE COLIMA   (Mexico)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

G protein coupled receptor; Smooth muscle

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; THROMBOXANE A2 RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL;

ANALYTIC METHOD; ANIMAL EXPERIMENT; CARBOXY TERMINAL SEQUENCE; CONFERENCE PAPER; ENERGY TRANSFER; GENE CASSETTE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RAT; REGULATORY MECHANISM;

RATTUS;

EID: 78650442667     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1002685107     Document Type: Article

References (23)

1. Toro L, Ramos-Franco J, Stefani E (1990) GTP-dependent regulation of myometrial KCa channels incorporated into lipid bilayers. J Gen Physiol 96:373-394.
2. Kume H, Graziano MP, Kotlikoff MI (1992) Stimulatory and inhibitory regulation of calcium-activated potassium channels by guanine nucleotide-binding proteins. Proc Natl Acad Sci USA 89:11051-11055.
3. Scornik FS, Codina J, Birnbaumer L, Toro L (1993) Modulation of coronary smooth muscle KCa channels by Gs alpha independent of phosphorylation by protein kinase A. Am J Physiol 265:H1460-H1465.
4. Liu G, et al. (2004) Assembly of a Ca2+-dependent BK channel signaling complex by binding to beta2 adrenergic receptor. EMBO J 23:2196-2205.
5. Scornik FS, Toro L (1992) U46619, a thromboxane A2 agonist, inhibits KCa channel activity from pig coronary artery. Am J Physiol 262:C708-C713.
6. Wu Y, et al. (2010) Quantitative determination of spatial protein-protein correlations in fluorescence confocal microscopy. Biophys J 98:493-504.
7. Wang GR, Zhu Y, Halushka PV, Lincoln TM, Mendelsohn ME (1998) Mechanism of platelet inhibition by nitric oxide: In vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase. Proc Natl Acad Sci USA 95:4888-4893.
8. Kelley LP, Kinsella BT (2003) The role of N-linked glycosylation in determining the surface expression, G protein interaction and effector coupling of the alpha (alpha) isoform of the human thromboxane A(2) receptor. Biochim Biophys Acta 1621:192-203.
9. Lu R, et al. (2008) c-Src tyrosine kinase, a critical component for 5-HT2A receptormediated contraction in rat aorta. J Physiol 586:3855-3869.
10. Pérez GJ, Bonev AD, Patlak JB, Nelson MT (1999) Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries. J Gen Physiol 113:229-238.
11. DeWire SM, Ahn S, Lefkowitz RJ, Shenoy SK (2007) Beta-arrestins and cell signaling. Annu Rev Physiol 69:483-510.
12. Thériault C, Rochdi MD, Parent JL (2004) Role of the Rab11-associated intracellular pool of receptors formed by constitutive endocytosis of the beta isoform of the thromboxane A2 receptor (TP beta). Biochemistry 43:5600-5607.
13. Liu F, et al. (2000) Direct protein-protein coupling enables cross-talk between dopamine D5 and gamma-aminobutyric acid A receptors. Nature 403:274-280.
14. Lee FJ, et al. (2002) Dual regulation of NMDA receptor functions by direct proteinprotein interactions with the dopamine D1 receptor. Cell 111:219-230.
15. Fiorentini C, Gardoni F, Spano P, Di Luca M, Missale C (2003) Regulation of dopamine D1 receptor trafficking and desensitization by oligomerization with glutamate Nmethyl-D-aspartate receptors. J Biol Chem 278:20196-20202.
16. Toro L, Amador M, Stefani E (1990) ANG II inhibits calcium-activated potassium channels from coronary smooth muscle in lipid bilayers. Am J Physiol 258:H912-H915.
17. Zhou XB, et al. (2008) M2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+channel activity. J Biol Chem 283:21036-21044.
18. Twitchell WA, Rane SG (1994) Nucleotide-independentmodulation of Ca(2+)-dependent K+ channel current by a mu-type opioid receptor. Mol Pharmacol 46:793-798.
19. Robertson BE, Schubert R, Hescheler J, Nelson MT (1993) cGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells. Am J Physiol 265:C299-C303.
20. Sadoshima J, Akaike N, Kanaide H, Nakamura M (1988) Cyclic AMP modulates Caactivated K channel in cultured smooth muscle cells of rat aortas. Am J Physiol 255: H754-H759.
21. Lange A, Gebremedhin D, Narayanan J, Harder D (1997) 20- Hydroxyeicosatetraenoic acid-induced vasoconstriction and inhibition of potassium current in cerebral vascular smooth muscle is dependent on activation of protein kinase C. J Biol Chem 272: 27345-27352.
22. Alioua A, et al. (2002) Coupling of c-Src to large conductance voltage- and Ca2+-activated K+ channels as a new mechanism of agonist-induced vasoconstriction. Proc Natl Acad Sci USA 99:14560-14565.
23. Lu T, et al. (2010) Regulation of coronary arterial BK channels by caveolae-mediated angiotensin II signaling in diabetes mellitus. Circ Res 106:1164-1173.