Gating properties conferred on BK channels by the β3b auxiliary subunit in the absence of its NH2- and COOH termini

Journal of General Physiology

Volumn 117, Issue 6, 2001, Pages 607-627

  Zeng, X H ^a   Ding, J P ^a   Xia, X M ^a   Lingle, C J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ca2+ and voltage gated K+ channels; Inactivation; K+ channels; mSlo channels; Voltage dependent gating

Indexed keywords

CALCIUM ION; POTASSIUM CHANNEL; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA CHAIN; CARBOXY TERMINAL SEQUENCE; CHANNEL GATING; CONCENTRATION RESPONSE; ELECTRIC POTENTIAL; MOLECULAR INTERACTION; NONHUMAN; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT;

ANIMALS; ELECTROPHYSIOLOGY; ION CHANNEL GATING; KINETICS; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; XENOPUS;

EID: 0034966691     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.117.6.607     Document Type: Article

References (45)

1. Calcium-activated potassium channels expressed from cloned complementary DNAs
2. A component of calcium-activated potassium channels encoded by the Drosophila slo locus
3. Cloning and functional characterization of novel large conductance calcium-activated potassium channel beta subunits, hKCNMB3 and hKCNMB4
4. mSlo, a complex mouse gene encoding "maxi" calcium-activated potassium channels
5. 2+ sensitivity
6. + channel
7. + channels
8. Inactivating BK channels in rat chromaffin cells may arise from heteromultimeric assembly of distinct inactivation-competent and noninactivating subunits
9. Purification and reconstitution of the high-conductance, calcium-activated potassium channel from tracheal smooth muscle
10. Functional reconstitution of the large-conductance, calcium-activated potassium channel purified from bovine aortic smooth muscle
11. +) channel gating kinetics by the S3-S4 linker
12. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
13. 2+
14. 2+
15. + channel from smooth muscle
16. Subunit composition of the high conductance calcium-activated potassium channel from smooth muscle, a representative of the mSlo and slowpoke family of potassium channels
17. Gating mechanism of a cloned potassium channel expressed in frog oocytes and mammalian cells
18. 2 terminus of the β3b auxiliary subunit involves a two-step mechanism: Possible separation of binding and blockade
19. Calcium-activated potassium channels: Regulation by calcium
20. Functional role of the beta subunit of high conductance calcium-activated potassium channels
21. + channels in rat skeletal muscle
22. A calcium switch for the functional coupling between alpha (hslo) and beta subunits (Kv, cabeta) of maxi K channels
23. + channel resistant to charybdotoxin and iberiotoxin
24. 2+ binding reactions
25. + channel: Evidence for a fluctuating barrier mechanism
26. 2+-activated potassium channels by retaining the gating in the bursting states
27. 2+-independent mechanism
28. Modulation of calcium-activated potassium channels from rat brain by protein kinase A and phosphatase 2A
29. 2+ suggest a two-tiered allosteric gating mechanism
30. + channels described by a two-tiered allosteric gating mechanism
31. Tetraethylammonium block of slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: Evidence for tetrameric channel formation
32. Preventing errors when estimating single channel properties from the analysis of current fluctuations
33. The cytosolic inactivation domains of BK channels in rat chromaffin cells do not behave like simple, open-channel blockers
34. Trypsin-sensitive, rapid inactivation of a calcium-activated potassium channel
35. Oxidative regulation of large conductance calcium-activated potassium channels
36. Alternative splicing switches potassium channel sensitivity to protein phosphorylation
37. A novel family of alternatively spliced BK β-subunits
38. Calcium -activated potassium channels
39. Characterization of and modulation by a beta-subunit of a human maxi KCa channel cloned from myometrium
40. + channels: A transmembrane beta-subunit homolog
41. + channels in smooth muscle cells
42. A novel nervous system beta subunit that downregulates human large conductance calcium-dependent potassium channels
43. 2+- and voltage-dependent BK channels in adrenal chromaffin cells and rat insulinoma tumor cells
44. 2+-activated, voltage-dependent BK currents: Consequences of rapid inactivation by a novel β subunit
45. Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle