All-atom structural models of insulin binding to the insulin receptor in the presence of a tandem hormone-binding element

Proteins: Structure, Function and Bioinformatics

Volumn 81, Issue 6, 2013, Pages 1017-1030

  Vashisth, Harish ^a   Abrams, Cameron F ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Drexel University   (United States)

Author keywords

Diabetes; Hormone recognition; Insulin receptor; Monte Carlo docking; String method; Temperature accelerated molecular dynamics

Indexed keywords

INSULIN; INSULIN RECEPTOR; SOMATOMEDIN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING KINETICS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CROSS LINKING; CRYSTALLOGRAPHY; HORMONE STRUCTURE; HYDROPHOBICITY; INSULIN BINDING; MOLECULAR DOCKING; MOLECULAR MODEL; MOLECULAR RECOGNITION; MONTE CARLO METHOD; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; SIMULATION; THERMODYNAMICS;

ANIMALS; HUMANS; INSULIN; MICE; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; MONTE CARLO METHOD; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECEPTOR, IGF TYPE 1; RECEPTOR, INSULIN; THERMODYNAMICS;

EID: 84878162584     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.24255     Document Type: Article

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