-
2
-
-
0000557482
-
Structure of rhombohedral 2 zinc insulin crystals
-
Adams, M. J., Blundell, T. L., Dodson, E. J., Dodson, G. G., Vijayan, M., Baker, E. N., Harding, M. M., Hodgkin, D. C., Rimmer, B., and Sheat, S.(1969). Structure of rhombohedral 2 zinc insulin crystals. Nature 224, 491-495.
-
(1969)
Nature
, vol.224
, pp. 491-495
-
-
Adams, M.J.1
Blundell, T.L.2
Dodson, E.J.3
Dodson, G.G.4
Vijayan, M.5
Baker, E.N.6
Harding, M.M.7
Hodgkin, D.C.8
Rimmer, B.9
Sheat, S.10
-
3
-
-
0033906634
-
Structure and function of the type 1 insulin-like growth factor receptor
-
Adams, T. E., Epa, V. C., Garrett, T. P., and Ward, C. W. (2000). Structure and function of the type 1 insulin-like growth factor receptor. Cell. Mol. Life Sci. 57, 1050-1093.
-
(2000)
Cell. Mol. Life Sci.
, vol.57
, pp. 1050-1093
-
-
Adams, T.E.1
Epa, V.C.2
Garrett, T.P.3
Ward, C.W.4
-
4
-
-
65549110812
-
A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II
-
Alvino, C. L., McNeil, K. A., Ong, S. C., Delaine, C., Booker, G. W., Wallace, J. C., Whittaker, J., and Forbes, B. E. (2009). A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II. J. Biol Chem. 284, 7656-7664.
-
(2009)
J. Biol Chem.
, vol.284
, pp. 7656-7664
-
-
Alvino, C.L.1
McNeil, K.A.2
Ong, S.C.3
Delaine, C.4
Booker, G.W.5
Wallace, J.C.6
Whittaker, J.7
Forbes, B.E.8
-
5
-
-
3142517219
-
The effect produced on diabetes by extracts of pancreas
-
Banting, F. G., Best, C. H., Col-lip, J. B., Campbell, W. R., Fletcher, A. A., MacLeod, J. J. R., and Noble, E. C. (1922). The effect produced on diabetes by extracts of pancreas. Trans. Assoc. Am. Physicians 37, 337-347.
-
(1922)
Trans. Assoc. Am. Physicians
, vol.37
, pp. 337-347
-
-
Banting, F.G.1
Best, C.H.2
Col-lip, J.B.3
Campbell, W.R.4
Fletcher, A.A.5
MacLeod, J.J.R.6
Noble, E.C.7
-
6
-
-
0032482220
-
Folding of insulin receptor monomers is facilitated by the molecular chaperones calnexin and calreticulin and impaired by rapid dimerization
-
Bass, J., Chiu, G., Argon, Y., and Steiner, D. F. (1998). Folding of insulin receptor monomers is facilitated by the molecular chaperones calnexin and calreticulin and impaired by rapid dimerization. J. Cell Biol. 141, 637-646.
-
(1998)
J. Cell Biol.
, vol.141
, pp. 637-646
-
-
Bass, J.1
Chiu, G.2
Argon, Y.3
Steiner, D.F.4
-
7
-
-
84892603248
-
Beijing Insulin Structure Group. Studies on crystal structure of insulin at 2 5Å
-
Beijing Insulin Structure Group. (1972). Studies on crystal structure of insulin at 2.5Å. Sci. Sin. 1, 3-30.
-
(1972)
Sci. Sin.
, vol.1
, pp. 3-30
-
-
-
8
-
-
0017195548
-
Structure of insulin in 4-zinc insulin
-
Bentley, G., Dodson, E., Dodson, G., Hodgkin,D.,andMercola,D. (1976). Structure of insulin in 4-zinc insulin. Nature 261,166-168.
-
(1976)
Nature
, vol.261
, pp. 166-168
-
-
Bentley, G.1
Dodson, E.2
Dodson, G.3
Hodgkin, D.4
Mercola, D.5
-
11
-
-
0025078913
-
Monomeric insulins and their experimental and clinical implications
-
Brange, J., Owens, D. R., Kang, S., and Volund, A. (1990). Monomeric insulins and their experimental and clinical implications. Diabetes Care 13,923-954.
-
(1990)
Diabetes Care
, vol.13
, pp. 923-954
-
-
Brange, J.1
Owens, D.R.2
Kang, S.3
Volund, A.4
-
12
-
-
34250306385
-
Complementation analysis demonstrates that insulin crosslinks both a subunits in a truncated insulin receptor dimer
-
Chan, S. J., Nakagawa, S., and Steiner, D. F. (2007). Complementation analysis demonstrates that insulin crosslinks both a subunits in a truncated insulin receptor dimer. J. Biol. Chem. 282,13754-13758.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 13754-13758
-
-
Chan, S.J.1
Nakagawa, S.2
Steiner, D.F.3
-
13
-
-
0014411801
-
Porcine proinsulin: characterization and amino acid sequence
-
Chance, R. E., Ellis, R. M., and Bromer, W. W. (1968). Porcine proinsulin: characterization and amino acid sequence. Science 161,165-167.
-
(1968)
Science
, vol.161
, pp. 165-167
-
-
Chance, R.E.1
Ellis, R.M.2
Bromer, W.W.3
-
14
-
-
0025873794
-
Quantitation of the class I disulfides of the insulin receptor
-
Chiacchia, K. B. (1991). Quantitation of the class I disulfides of the insulin receptor. Biochem. Biophys. Res. Commun. 176,1178-1182.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.176
, pp. 1178-1182
-
-
Chiacchia, K.B.1
-
15
-
-
16144366886
-
Purification and properties of insulin receptor ectodomain from large-scale mammalian cell culture
-
Cosgrove, L., Lovrecz, G. O., Verkuylen, A., Cavaleri, L., Black, L. A., Bent-ley, J. D., Howlett, G. J., Gray, P. P., Ward, C. W., and McKern, N. M. (1995). Purification and properties of insulin receptor ectodomain from large-scale mammalian cell culture. Protein Expr. Purif. 6, 789-798.
-
(1995)
Protein Expr. Purif.
, vol.6
, pp. 789-798
-
-
Cosgrove, L.1
Lovrecz, G.O.2
Verkuylen, A.3
Cavaleri, L.4
Black, L.A.5
Bent-ley, J.D.6
Howlett, G.J.7
Gray, P.P.8
Ward, C.W.9
McKern, N.M.10
-
16
-
-
34250895565
-
Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region
-
Craddock, B. P., Cotter, C., and Miller, W. T. (2007). Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region. FEBS Lett. 581,3235-3240.
-
(2007)
FEBS Lett
, vol.581
, pp. 3235-3240
-
-
Craddock, B.P.1
Cotter, C.2
Miller, W.T.3
-
17
-
-
0041676177
-
X-ray single crystal photographs of insulin
-
Crowfoot, D. (1935). X-ray single crystal photographs of insulin. Nature 135,591-592.
-
(1935)
Nature
, vol.135
, pp. 591-592
-
-
Crowfoot, D.1
-
18
-
-
0015229029
-
Insulin-receptor interactions in liver cell membranes
-
Cuatrecasas, P., Desbuquois, B., and Krug, F. (1971). Insulin-receptor interactions in liver cell membranes. Biochem. Biophys. Res. Commun. 44, 333-339.
-
(1971)
Biochem. Biophys. Res. Commun.
, vol.44
, pp. 333-339
-
-
Cuatrecasas, P.1
Desbuquois, B.2
Krug, F.3
-
19
-
-
0028146822
-
The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling
-
De Meyts, P. (1994). The structural basis of insulin and insulin-like growth factor-I receptor binding and negative co-operativity, and its relevance to mitogenic versus metabolic signalling. Diabetologia 37(Suppl. 2), S135-S148.
-
(1994)
Diabetologia
, vol.37
, Issue.SUPPL. 2
-
-
De Meyts, P.1
-
20
-
-
10844223660
-
Insulin and its receptor: structure, function and evolution
-
De Meyts, P. (2004). Insulin and its receptor: structure, function and evolution. Bioessays 26,1351-1362.
-
(2004)
Bioessays
, vol.26
, pp. 1351-1362
-
-
De Meyts, P.1
-
21
-
-
5044227353
-
Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus iso-form of the IR
-
Denley, A., Bonython, E. R., Booker, G. W., Cosgrove, L. J., Forbes, B. E., Ward, C. W., and Wallace, J. C. (2004). Structural determinants for high-affinity binding of insulin-like growth factor II to insulin receptor (IR)-A, the exon 11 minus iso-form of the IR. Mol. Endocrinol. 18, 2502-2512.
-
(2004)
Mol. Endocrinol.
, vol.18
, pp. 2502-2512
-
-
Denley, A.1
Bonython, E.R.2
Booker, G.W.3
Cosgrove, L.J.4
Forbes, B.E.5
Ward, C.W.6
Wallace, J.C.7
-
22
-
-
0025880180
-
X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule
-
Derewenda, U., Derewenda, Z., Dodson, E. J., Dodson, G. G., Bing, X., and Markussen, J. (1991). X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue. J. Mol. Biol. 220,425-433.
-
(1991)
A completely inactive analogue. J. Mol. Biol.
, vol.220
, pp. 425-433
-
-
Derewenda, U.1
Derewenda, Z.2
Dodson, E.J.3
Dodson, G.G.4
Bing, X.5
Markussen, J.6
-
23
-
-
0021924895
-
The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling
-
Ebina, Y., Ellis, L., Jarnagin, K., Edery, M., Graf, L., Clauser, E., Ou, J. H., Masiarz, F., Kan, Y. W., Goldfine, I. D., Roth, R. A., and Rutter, W. J. (1985). The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell 40, 747-758.
-
(1985)
Cell
, vol.40
, pp. 747-758
-
-
Ebina, Y.1
Ellis, L.2
Jarnagin, K.3
Edery, M.4
Graf, L.5
Clauser, E.6
Ou, J.H.7
Masiarz, F.8
Kan, Y.W.9
Goldfine, I.D.10
Roth, R.A.11
Rutter, W.J.12
-
24
-
-
0025023537
-
Labile disulfide bonds in human placental insulin receptor
-
Finn, F. M., Ridge, K. D., and Hofmann, K. (1990). Labile disulfide bonds in human placental insulin receptor. Proc. Natl. Acad. Sci. U.S.A. 87, 419-423.
-
(1990)
Proc. Natl. Acad. Sci. U. S. A.
, vol.87
, pp. 419-423
-
-
Finn, F.M.1
Ridge, K.D.2
Hofmann, K.3
-
25
-
-
0032932822
-
Insulin receptor isof orm A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells
-
Frasca, F., Pandini, G., Scalia, P., Sci-acca, L., Mineo, R., Costantino, A., Goldfine, I. D., Belfiore, A., and Vigneri, R. (1999). Insulin receptor isof orm A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol. Cell. Biol. 19, 3278-3288.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 3278-3288
-
-
Frasca, F.1
Pandini, G.2
Scalia, P.3
Sci-acca, L.4
Mineo, R.5
Costantino, A.6
Goldfine, I.D.7
Belfiore, A.8
Vigneri, R.9
-
26
-
-
0015103371
-
Insulin receptors in the liver: specific binding of [125I]insulin to the plasma membrane and its relation to insulin bioactivity
-
Freychet, P., Roth, J., and Neville, D. M. Jr. (1971). Insulin receptors in the liver: specific binding of [125I]insulin to the plasma membrane and its relation to insulin bioactivity. Proc. Natl. Acad. Sci. U.S.A. 68, 1833-1837.
-
(1971)
Proc. Natl. Acad. Sci. U. S. A.
, vol.68
, pp. 1833-1837
-
-
Freychet, P.1
Roth, J.2
Neville Jr, D.M.3
-
27
-
-
0015698573
-
Binding and degradation of 125I-labelled insulin by isolated rat fat cells
-
Gammeltoft, S., and Gliemann, J. (1973). Binding and degradation of 125I-labelled insulin by isolated rat fat cells. Biochim. Biophys. Acta 320, 16-32.
-
(1973)
Biochim. Biophys. Acta
, vol.320
, pp. 16-32
-
-
Gammeltoft, S.1
Gliemann, J.2
-
28
-
-
0032560753
-
Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor
-
Garrett, T. P., McKern, N. M., Lou, M., Frenkel, M. J., Bentley, J. D., Lovrecz, G. O., Elleman, T. C., Cosgrove, L. J., and Ward, C.W. (1998). Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor. Nature 394, 395-399.
-
(1998)
Nature
, vol.394
, pp. 395-399
-
-
Garrett, T.P.1
McKern, N.M.2
Lou, M.3
Frenkel, M.J.4
Bentley, J.D.5
Lovrecz, G.O.6
Elleman, T.C.7
Cosgrove, L.J.8
Ward, C.W.9
-
29
-
-
48149095541
-
Ala-nine scanning of a putative receptor binding surface of insulin-like growth factor-I
-
Gauguin, L., Delaine, C., Alvino, C. L., McNeil, K. A., Wallace, J. C., Forbes, B. E., and De Meyts, P. (2008). Ala-nine scanning of a putative receptor binding surface of insulin-like growth factor-I. J. Biol. Chem. 283, 20821-20829.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 20821-20829
-
-
Gauguin, L.1
Delaine, C.2
Alvino, C.L.3
McNeil, K.A.4
Wallace, J.C.5
Forbes, B.E.6
De Meyts, P.7
-
30
-
-
42349087938
-
Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding
-
Glendorf, T., Sorensen, A. R., Nishimura, E., Pettersson, I., and Kjeldsen, T. (2008). Importance of the solvent-exposed residues of the insulin B chain alpha-helix for receptor binding. Biochemistry 47, 4743-4751.
-
(2008)
Biochemistry
, vol.47
, pp. 4743-4751
-
-
Glendorf, T.1
Sorensen, A.R.2
Nishimura, E.3
Pettersson, I.4
Kjeldsen, T.5
-
31
-
-
0014938487
-
Characterization of an [125 I]-insulin binding plasma membrane fraction from rat liver
-
House, P. D., and Weidemann, M. J. (1970). Characterization of an [125 I]-insulin binding plasma membrane fraction from rat liver. Biochem. Biophys. Res. Commun. 41, 541-548.
-
(1970)
Biochem. Biophys. Res. Commun.
, vol.41
, pp. 541-548
-
-
House, P.D.1
Weidemann, M.J.2
-
32
-
-
0025996911
-
Receptor binding redefined by a structural switch in a mutant human insulin
-
Hua, Q. X., Shoelson, S. E., Kochoyan, M., and Weiss, M. A. (1991). Receptor binding redefined by a structural switch in a mutant human insulin. Nature 354, 238-241.
-
(1991)
Nature
, vol.354
, pp. 238-241
-
-
Hua, Q.X.1
Shoelson, S.E.2
Kochoyan, M.3
Weiss, M.A.4
-
33
-
-
0030766163
-
Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog
-
Hubbard, S. R. (1997). Crystal structure of the activated insulin receptor tyrosine kinase in complex with peptide substrate and ATP analog. EMBOJ. 16,5572-5581.
-
(1997)
EMBOJ
, vol.16
, pp. 5572-5581
-
-
Hubbard, S.R.1
-
34
-
-
0028582185
-
Crystal structure of the tyrosine kinase domain of the human insulin receptor
-
Hubbard, S. R., Wei, L., Ellis, L., and Hendrickson, W A. (1994). Crystal structure of the tyrosine kinase domain of the human insulin receptor. Nature 372, 746-754.
-
(1994)
Nature
, vol.372
, pp. 746-754
-
-
Hubbard, S.R.1
Wei, L.2
Ellis, L.3
Hendrickson, W.A.4
-
36
-
-
76649083949
-
Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues
-
Jiracek, J., Zakova, L., Antolikova, E., Watson, C. J., Turkenburg, J. P., Dodson, G. G., and Brzozowski, A. M. (2010). Implications for the active form of human insulin based on the structural convergence of highly active hormone analogues. Proc. Natl. Acad. Sci. U.S.A. 107, 1966-1970.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 1966-1970
-
-
Jiracek, J.1
Zakova, L.2
Antolikova, E.3
Watson, C.J.4
Turkenburg, J.P.5
Dodson, G.G.6
Brzozowski, A.M.7
-
37
-
-
0037773543
-
Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling
-
Johnston, A. M., Pirola, L., and Van Obberghen, E. (2003). Molecular mechanisms of insulin receptor substrate protein-mediated modulation of insulin signalling. FEBS Lett. 546, 32-36.
-
(2003)
FEBS Lett
, vol.546
, pp. 32-36
-
-
Johnston, A.M.1
Pirola, L.2
Van Obberghen, E.3
-
38
-
-
0020360817
-
Insulin stimulation of phosphorylation of the beta sub-unit of the insulin receptor
-
Kasuga, M., Zick, Y., Blith, D. L., Karls-son, F. A., Haring, H. U., and Kahn, C. R. (1982a). Insulin stimulation of phosphorylation of the beta sub-unit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine. J. Biol. Chem. 257, 9891-9894.
-
(1982)
Formation of both phosphoserine and phosphotyrosine. J. Biol. Chem.
, vol.257
, pp. 9891-9894
-
-
Kasuga, M.1
Zick, Y.2
Blith, D.L.3
Karls-son, F.A.4
Haring, H.U.5
Kahn, C.R.6
-
39
-
-
0020046655
-
Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system
-
Kasuga, M., Zick, Y., Blithe, D. L., Cret-taz, M., and Kahn, C. R. (1982b). Insulin stimulates tyrosine phosphorylation of the insulin receptor in a cell-free system. Nature 298, 667-669.
-
(1982)
Nature
, vol.298
, pp. 667-669
-
-
Kasuga, M.1
Zick, Y.2
Blithe, D.L.3
Cret-taz, M.4
Kahn, C.R.5
-
40
-
-
0642285438
-
A history of insulin: from discovery to modern alternatives
-
King, K. M. (2003). A history of insulin: from discovery to modern alternatives. Br. I Nurs. 12, 1137-1141.
-
(2003)
Br. I Nurs.
, vol.12
, pp. 1137-1141
-
-
King, K.M.1
-
41
-
-
0026326821
-
Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adeno-sine monophosphate-dependent protein kinase
-
Knighton, D. R., Zheng, J. H., Ten Eyck, L. F., Xuong, N. H., Taylor, S. S., and Sowadski, J. M. (1991). Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adeno-sine monophosphate-dependent protein kinase. Science 253, 414-420.
-
(1991)
Science
, vol.253
, pp. 414-420
-
-
Knighton, D.R.1
Zheng, J.H.2
Ten Eyck, L.F.3
Xuong, N.H.4
Taylor, S.S.5
Sowadski, J.M.6
-
42
-
-
0037166344
-
Functional reconstitution of insulin receptor binding site from non-binding receptor fragments
-
Kristensen, C., Andersen, A. S., Øster-gaard, S., Hansen, P. H., and Brandt, J. (2002). Functional reconstitution of insulin receptor binding site from non-binding receptor fragments. J. Biol. Chem. 277, 18340-18345.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 18340-18345
-
-
Kristensen, C.1
Andersen, A.S.2
Øster-gaard, S.3
Hansen, P.H.4
Brandt, J.5
-
43
-
-
0032504250
-
Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin
-
Kristensen, C., Wiberg, F. C., Schäf-fer, L., and Andersen, A. S. (1998). Expression and characterization of a 70-kDa fragment of the insulin receptor that binds insulin. Minimizing ligand binding domain of the insulin receptor. J. Biol. Chem. 273, 17780-17786.
-
(1998)
Minimizing ligand binding domain of the insulin receptor. J. Biol. Chem.
, vol.273
, pp. 17780-17786
-
-
Kristensen, C.1
Wiberg, F.C.2
Schäf-fer, L.3
Andersen, A.S.4
-
44
-
-
0027960567
-
Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the α-subunit of the insulin receptor
-
Kurose, T., Pashmforoush, M., Yoshi-masa, Y., Carroll, R., Schwartz, G. P., Burke, G. T., Katsoyannis, P. G., and Steiner, D. F. (1994). Cross-linking of a B25 azidophenylalanine insulin derivative to the carboxyl-terminal region of the α-subunit of the insulin receptor. Identification of a new insulin-binding domain in the insulin receptor. J. Biol. Chem. 269, 29190-29197.
-
(1994)
Identification of a new insulin-binding domain in the insulin receptor. J. Biol. Chem.
, vol.269
, pp. 29190-29197
-
-
Kurose, T.1
Pashmforoush, M.2
Yoshi-masa, Y.3
Carroll, R.4
Schwartz, G.P.5
Burke, G.T.6
Katsoyannis, P.G.7
Steiner, D.F.8
-
45
-
-
36549015742
-
Insulin receptor structure and its implications for the IGF-1 receptor
-
Lawrence, M. C., McKern, N. M., and Ward, C. W (2007). Insulin receptor structure and its implications for the IGF-1 receptor. Curr. Opin. Struct. Biol. 17, 699-705.
-
(2007)
Curr. Opin. Struct. Biol.
, vol.17
, pp. 699-705
-
-
Lawrence, M.C.1
McKern, N.M.2
Ward, C.W.3
-
46
-
-
0010989599
-
The action of insulin on the distribution of galactose in eviscerated nephrec-tomized dogs
-
Levine, R., Goldstein, M., Klein, S., and Huddlestun, B. (1949). The action of insulin on the distribution of galactose in eviscerated nephrec-tomized dogs. J. Biol. Chem. 179, 985.
-
(1949)
J. Biol. Chem.
, vol.179
, pp. 985
-
-
Levine, R.1
Goldstein, M.2
Klein, S.3
Huddlestun, B.4
-
47
-
-
0038168241
-
Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor
-
Li, S., Covino, N. D., Stein, E. G., Till, J. H., and Hubbard, S. R. (2003). Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor. J. Biol. Chem. 278,26007-26014.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26007-26014
-
-
Li, S.1
Covino, N.D.2
Stein, E.G.3
Till, J.H.4
Hubbard, S.R.5
-
48
-
-
33747584896
-
The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity
-
Lou, M., Garrett, T. P., McKern, N. M., Hoyne, P. A., Epa, V. C., Bentley, J. D., Lovrecz, G. O., Cosgrove, L. J., Frenkel, M. J., and Ward, C. W (2006). The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity. Proc. Natl. Acad. Sci. U.S.A. 103, 12429-12434.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 12429-12434
-
-
Lou, M.1
Garrett, T.P.2
McKern, N.M.3
Hoyne, P.A.4
Epa, V.C.5
Bentley, J.D.6
Lovrecz, G.O.7
Cosgrove, L.J.8
Frenkel, M.J.9
Ward, C.W.10
-
49
-
-
0032577326
-
A structural switch in a mutant insulin exposes key residues for receptor binding
-
Ludvigsen, S., Olsen, H. B., and Kaarsholm, N. C. (1998). A structural switch in a mutant insulin exposes key residues for receptor binding. J. Mol. Biol. 279, 1-7.
-
(1998)
J. Mol. Biol.
, vol.279
, pp. 1-7
-
-
Ludvigsen, S.1
Olsen, H.B.2
Kaarsholm, N.C.3
-
50
-
-
34250641161
-
High-throughput phosphotyrosine profiling using SH2 domains
-
Machida, K., Thompson, C. M., Dierck, K., Jablonowski, K., Karkkainen, S., Liu, B., Zhang, H., Nash, P. D., Newman, D. K., Nollau, P., Paw-son, T., Renkema, G. H., Saksela, K., Schiller, M. R., Shin, D. G., and Mayer, B. J. (2007). High-throughput phosphotyrosine profiling using SH2 domains. Mol. Cell 26, 899-915.
-
(2007)
Mol. Cell
, vol.26
, pp. 899-915
-
-
Machida, K.1
Thompson, C.M.2
Dierck, K.3
Jablonowski, K.4
Karkkainen, S.5
Liu, B.6
Zhang, H.7
Nash, P.D.8
Newman, D.K.9
Nollau, P.10
Paw-son, T.11
Renkema, G.H.12
Saksela, K.13
Schiller, M.R.14
Shin, D.G.15
Mayer, B.J.16
-
51
-
-
0009632799
-
Electrophoretic resolution of three major insulin receptor structures with unique subunit sto-ichiometries
-
Massague, J., Pilch, P. F., and Czech, M. P. (1980). Electrophoretic resolution of three major insulin receptor structures with unique subunit sto-ichiometries. Proc. Natl. Acad. Sci. U.S.A. 77, 7137-7141.
-
(1980)
Proc. Natl. Acad. Sci. U. S. A.
, vol.77
, pp. 7137-7141
-
-
Massague, J.1
Pilch, P.F.2
Czech, M.P.3
-
52
-
-
33748639228
-
Structure of the insulin receptor ectodomain reveals a folded-over conformation
-
McKern, N. M., Lawrence, M. C., Streltsov, V. A., Lou, M. Z., Adams, T. E., Lovrecz, G. O., Elleman, T. C., Richards, K. M., Bentley, J. D., Pilling, P. A., Hoyne, P. A., Cartledge, K. A., Pham, T. M., Lewis, J. L., Sankovich, S. E., Stoichevska, V., Da Silva, E., Robinson, C. P., Frenkel, M. J., Sparrow, L. G., Fernley, R. T., Epa, V. C., and Ward, C. W. (2006). Structure of the insulin receptor ectodomain reveals a folded-over conformation. Nature 443, 218-221.
-
(2006)
Nature
, vol.443
, pp. 218-221
-
-
McKern, N.M.1
Lawrence, M.C.2
Streltsov, V.A.3
Lou, M.Z.4
Adams, T.E.5
Lovrecz, G.O.6
Elleman, T.C.7
Richards, K.M.8
Bentley, J.D.9
Pilling, P.A.10
Hoyne, P.A.11
Cartledge, K.A.12
Pham, T.M.13
Lewis, J.L.14
Sankovich, S.E.15
Stoichevska, V.16
Da Silva, E.17
Robinson, C.P.18
Frenkel, M.J.19
Sparrow, L.G.20
Fernley, R.T.21
Epa, V.C.22
Ward, C.W.23
more..
-
53
-
-
67049158418
-
A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor α-chain C-terminal peptide and the site 1 insulin mimetic peptides
-
Menting, J. G., Ward, C. W., Margetts, M. B., and Lawrence, M. C. (2009). A thermodynamic study of ligand binding to the first three domains of the human insulin receptor: relationship between the receptor α-chain C-terminal peptide and the site 1 insulin mimetic peptides. Biochemistry 48,5492-5500.
-
(2009)
Biochemistry
, vol.48
, pp. 5492-5500
-
-
Menting, J.G.1
Ward, C.W.2
Margetts, M.B.3
Lawrence, M.C.4
-
54
-
-
0030756092
-
Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors Insights into mechanisms of ligand binding
-
Mynarcik, D. C., Williams, P. F., Schäf-fer, L., Yu, G. Q., and Whittaker, J. (1997). Identification of common ligand binding determinants of the insulin and insulin-like growth factor 1 receptors. Insights into mechanisms of ligand binding. J. Biol. Chem. 272, 18650-18655.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18650-18655
-
-
Mynarcik, D.C.1
Williams, P.F.2
Schäf-fer, L.3
Yu, G.Q.4
Whittaker, J.5
-
55
-
-
13344279398
-
Alanine-scanning mutagenesis of a C-terminal ligand binding domain of the insulin receptor α subunit
-
Mynarcik, D. C., Yu, G. Q., and Whittaker, J. (1996). Alanine-scanning mutagenesis of a C-terminal ligand binding domain of the insulin receptor α subunit. J. Biol. Chem. 271, 2439-2442.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 2439-2442
-
-
Mynarcik, D.C.1
Yu, G.Q.2
Whittaker, J.3
-
56
-
-
16344376210
-
Chiral mutagenesis of insulin
-
Nakagawa, S. H., Zhao, M., Hua, Q. X., Hu, S. Q., Wan, Z. L., Jia, W., and Weiss, M. A. (2005). Chiral mutagenesis of insulin. Foldability and function are inversely regulated by a stereospecific switch in the B chain. Biochemistry 44, 4984-4999.
-
(2005)
Foldability and function are inversely regulated by a stereospecific switch in the B chain. Biochemistry
, vol.44
, pp. 4984-4999
-
-
Nakagawa, S.H.1
Zhao, M.2
Hua, Q.X.3
Hu, S.Q.4
Wan, Z.L.5
Jia, W.6
Weiss, M.A.7
-
57
-
-
84892605940
-
-
Novo Nordisk. (2009). History ofNovo Nordisk. Available: http:// www. novonordisk.com.au/documents/ article_ page/document/ History.asp
-
(2009)
History ofNovo Nordisk
-
-
Nordisk, N.1
-
58
-
-
0035575586
-
SH2 domains, interaction modules and cellular wiring
-
Pawson, T., Gish, G. D., and Nash, P. (2001). SH2 domains, interaction modules and cellular wiring. Trends Cell Biol. 11,504-511.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 504-511
-
-
Pawson, T.1
Gish, G.D.2
Nash, P.3
-
59
-
-
0036885616
-
Insulin: discovery and controversy
-
Rosenfeld, L. (2002). Insulin: discovery and controversy. Clin. Chem. 48, 2270-2288.
-
(2002)
Clin. Chem.
, vol.48
, pp. 2270-2288
-
-
Rosenfeld, L.1
-
60
-
-
0000410878
-
Fractionation of oxidized insulin
-
Sanger, E (1949). Fractionation of oxidized insulin. Biochem. J. 44, 126-128.
-
(1949)
Biochem. J.
, vol.44
, pp. 126-128
-
-
Sanger, E.1
-
61
-
-
77049132676
-
The amino-acid sequence in the glycyl chain of insulin I. The identification of lower peptides from partial hydrolysates
-
Sanger, F., and Thompson, E. O. (1953a). The amino-acid sequence in the glycyl chain of insulin. I. The identification of lower peptides from partial hydrolysates. Biochem. J. 53, 353-366.
-
(1953)
Biochem. J.
, vol.53
, pp. 353-366
-
-
Sanger, F.1
Thompson, E.O.2
-
62
-
-
77049157238
-
The amino-acid sequence in the glycyl chain of insulin II. The investigation of peptides from enzymic hydrolysates
-
Sanger, F., and Thompson, E. O. (1953b). The amino-acid sequence in the glycyl chain of insulin. II. The investigation of peptides from enzymic hydrolysates. Biochem. J. 53, 366-374.
-
(1953)
Biochem. J.
, vol.53
, pp. 366-374
-
-
Sanger, F.1
Thompson, E.O.2
-
63
-
-
76949111135
-
The amino-acid sequence in the pheny-lalanyl chain of insulin 1. The identification of lower peptides from partial hydrolysates
-
Sanger, F., and Tuppy, H. (1951a). The amino-acid sequence in the pheny-lalanyl chain of insulin. 1. The identification of lower peptides from partial hydrolysates. Biochem. J. 49, 463-481.
-
(1951)
Biochem. J.
, vol.49
, pp. 463-481
-
-
Sanger, F.1
Tuppy, H.2
-
64
-
-
84958255174
-
The amino-acid sequence in the phenylalanyl chain of insulin 2. The investigation of peptides from enzymic hydrolysates
-
Sanger, F., and Tuppy, H. (1951b). The amino-acid sequence in the phenylalanyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates. Biochem. J. 49, 481-490.
-
(1951)
Biochem. J.
, vol.49
, pp. 481-490
-
-
Sanger, F.1
Tuppy, H.2
-
65
-
-
0028268592
-
A model for insulin binding to the insulin receptor
-
Schäffer, L. (1994). A model for insulin binding to the insulin receptor. Eur. I Biochem.221, 1127-1132.
-
(1994)
Eur. I Biochem
, vol.221
, pp. 1127-1132
-
-
Schäffer, L.1
-
66
-
-
61349161851
-
The human insulin superfamily of polypeptide hormones
-
Shabanpoor, F., Separovic, F., and Wade, J. D. (2009). The human insulin superfamily of polypeptide hormones. Vitam. Horm. 80,1-31.
-
(2009)
Vitam. Horm.
, vol.80
, pp. 1-31
-
-
Shabanpoor, F.1
Separovic, F.2
Wade, J.D.3
-
67
-
-
79961004321
-
Signalling by insulin and IGF receptors: supporting acts and new players
-
Siddle, K. (2011). Signalling by insulin and IGF receptors: supporting acts and new players. J. Mol. Endocrinol. 47, R1-R10.
-
(2011)
J. Mol. Endocrinol.
, vol.47
-
-
Siddle, K.1
-
68
-
-
33947340530
-
The molecular weight of insulin
-
Sjögren,B.,andSvedberg,T. (1931).The molecular weight of insulin. J. Am. Chem. Soc. 53,2657-2661.
-
(1931)
J. Am. Chem. Soc.
, vol.53
, pp. 2657-2661
-
-
Sjögren, B.1
Svedberg, T.2
-
69
-
-
0026088633
-
Identification of a cDNA encoding a second putative prohor-mone convertase related to PC2 in AtT20 cells and islets of Langer-hans
-
Smeekens, S. P., Avruch, A. S., LaMen-dola, J., Chan, S. J., and Steiner, D. E (1991). Identification of a cDNA encoding a second putative prohor-mone convertase related to PC2 in AtT20 cells and islets of Langer-hans. Proc. Natl. Acad. Sci. U.S.A. 88, 340-344.
-
(1991)
Proc. Natl. Acad. Sci. U. S. A.
, vol.88
, pp. 340-344
-
-
Smeekens, S.P.1
Avruch, A.S.2
LaMen-dola, J.3
Chan, S.J.4
Steiner, D.E.5
-
70
-
-
0025214491
-
Identification of a human insuli-noma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2
-
Smeekens,S. P.,and Steiner, D.F. (1990). Identification of a human insuli-noma cDNA encoding a novel mammalian protein structurally related to the yeast dibasic processing protease Kex2. J. Biol. Chem. 265, 2997-3000.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 2997-3000
-
-
Smeekens, S.P.1
Steiner, D.F.2
-
71
-
-
77951058594
-
Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists
-
Smith, B. J., Huang, K., Kong, G., Chan, S. J., Nakagawa, S., Menting, J. G., Hu, S.-Q., Whittaker, J., Steiner, D. F., Katsoyannis, P. G., Ward, C. W., Weiss, M. A., and Lawrence, M. C. (2010). Structural resolution of a tandem hormone-binding element in the insulin receptor and its implications for design of peptide agonists. Proc. Natl. Acad. Sci. U.S.A. 107, 6771-6776.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 6771-6776
-
-
Smith, B.J.1
Huang, K.2
Kong, G.3
Chan, S.J.4
Nakagawa, S.5
Menting, J.G.6
Hu, S.-Q.7
Whittaker, J.8
Steiner, D.F.9
Katsoyannis, P.G.10
Ward, C.W.11
Weiss, M.A.12
Lawrence, M.C.13
-
72
-
-
0022474285
-
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor
-
Soos, M. A., Siddle, K., Baron, M. D., Heward, J. M., Luzio, J. P., Bellatin, J., and Lennox, E. S. (1986). Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor. Biochem. J. 235,199-208.
-
(1986)
Biochem. J.
, vol.235
, pp. 199-208
-
-
Soos, M.A.1
Siddle, K.2
Baron, M.D.3
Heward, J.M.4
Luzio, J.P.5
Bellatin, J.6
Lennox, E.S.7
-
73
-
-
33845998948
-
The location and characterisation of the O-linked glycans of the human insulin receptor
-
Sparrow, L. G., Gorman, J. J., Strike, P. M., Robinson, C. P., McKern, N. M., Epa, V. C., and Ward, C. W. (2007a). The location and characterisation of the O-linked glycans of the human insulin receptor. Proteins Struct. Funct. Bioinform. 66, 261-265.
-
(2007)
Proteins Struct. Funct. Bioinform.
, vol.66
, pp. 261-265
-
-
Sparrow, L.G.1
Gorman, J.J.2
Strike, P.M.3
Robinson, C.P.4
McKern, N.M.5
Epa, V.C.6
Ward, C.W.7
-
74
-
-
40549117199
-
N-linked glycans of the human insulin receptor and their distribution over the crystal structure
-
Sparrow, L. G., Lawrence, M. C., Gorman, J. J., Strike, P. M., Robinson, C. P., McKern, N. M., and Ward, C. W. (2007b). N-linked glycans of the human insulin receptor and their distribution over the crystal structure. Proteins Struct. Funct. Bioinform. 71,426-439.
-
(2007)
Proteins Struct. Funct. Bioinform.
, vol.71
, pp. 426-439
-
-
Sparrow, L.G.1
Lawrence, M.C.2
Gorman, J.J.3
Strike, P.M.4
Robinson, C.P.5
McKern, N.M.6
Ward, C.W.7
-
75
-
-
0030662658
-
The disulfide bonds in the C-terminal domains of the human insulin receptor ectodomain
-
Sparrow, L. G., McKern, N. M., Gorman, J. J., Strike, P. M., Robinson, C. P., Bentley, J. D., and Ward, C. W. (1997). The disulfide bonds in the C-terminal domains of the human insulin receptor ectodomain. J. Biol. Chem. 272, 29460-29467.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 29460-29467
-
-
Sparrow, L.G.1
McKern, N.M.2
Gorman, J.J.3
Strike, P.M.4
Robinson, C.P.5
Bentley, J.D.6
Ward, C.W.7
-
76
-
-
79960958485
-
Adventures with Insulin in the Islets of Langerhans
-
Steiner, D. E (2011). Adventures with Insulin in the Islets of Langerhans. J. Biol. Chem. 286, 17399-17241.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 17399-17241
-
-
Steiner, D.E.1
-
77
-
-
0014200189
-
Insulin biosynthesis: evidence for a precursor
-
Steiner, D. F., Cunningham, D., Spigel-man, L.,andAten, B. (1967). Insulin biosynthesis: evidence for a precursor. Science 157,697-700.
-
(1967)
Science
, vol.157
, pp. 697-700
-
-
Steiner, D.F.1
Cunningham, D.2
Spigel-man, L.3
Aten, B.4
-
78
-
-
0000962628
-
The biosynthesis of insulin and a probable precursor of insulin by a human islet cell adenoma
-
Steiner, D. F., and Oyer, P. E. (1967). The biosynthesis of insulin and a probable precursor of insulin by a human islet cell adenoma. Proc. Natl. Acad. Sci. U.S.A. 57, 473-480.
-
(1967)
Proc. Natl. Acad. Sci. U. S. A.
, vol.57
, pp. 473-480
-
-
Steiner, D.F.1
Oyer, P.E.2
-
79
-
-
0025813375
-
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
-
Sun, X. J., Rothenberg, P., Kahn, C. R., Backer, J. M., Araki, E., Wilden, P. A., Cahill, D. A., Goldstein, B. J., and White, M. E (1991). Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein. Nature 352, 73-77.
-
(1991)
Nature
, vol.352
, pp. 73-77
-
-
Sun, X.J.1
Rothenberg, P.2
Kahn, C.R.3
Backer, J.M.4
Araki, E.5
Wilden, P.A.6
Cahill, D.A.7
Goldstein, B.J.8
White, M.E.9
-
80
-
-
0037053344
-
Role of insulin receptor dimerization domains in ligand binding, cooperativity, and modulation by anti-receptor antibodies
-
Surinya, K. H., Molina, L., Soos, M. A., Brandt, J., Kristensen, C., and Siddle, K. (2002). Role of insulin receptor dimerization domains in ligand binding, cooperativity, and modulation by anti-receptor antibodies. J. Biol. Chem. 277,16718-16725.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16718-16725
-
-
Surinya, K.H.1
Molina, L.2
Soos, M.A.3
Brandt, J.4
Kristensen, C.5
Siddle, K.6
-
81
-
-
0021985413
-
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
-
Ullrich, A., Bell, J. R., Chen, E. Y., Her-rera, R., Petruzzelli, L. M., Dull, T. J., Gray, A., Coussens, L., Liao, Y. C., Tsubokawa, M., Mason, A., See-burg, P. H., Grunfeld, C., Rosen, O. M., and Ramachandran, J. (1985). Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature 313,756-761.
-
(1985)
Nature
, vol.313
, pp. 756-761
-
-
Ullrich, A.1
Bell, J.R.2
Chen, E.Y.3
Her-rera, R.4
Petruzzelli, L.M.5
Dull, T.J.6
Gray, A.7
Coussens, L.8
Liao, Y.C.9
Tsubokawa, M.10
Mason, A.11
See-burg, P.H.12
Grunfeld, C.13
Rosen, O.M.14
Ramachandran, J.15
-
82
-
-
0022800838
-
Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity
-
Ullrich, A., Gray, A., Tam, A. W., Yang-Feng, T., Tsubokawa, M., Collins, C.,Henzel, W., Le Bon, T., Kathuria, S., Chen, E., Jaobs, S., Francke, U., Ramachandran, J., and Fujita-Yamaguchi, Y. (1986). Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBOJ. 5,2503-2512.
-
(1986)
EMBOJ
, vol.5
, pp. 2503-2512
-
-
Ullrich, A.1
Gray, A.2
Tam, A.W.3
Yang-Feng, T.4
Tsubokawa, M.5
Collins, C.6
Henzel, W.7
Le Bon, T.8
Kathuria, S.9
Chen, E.10
Jaobs, S.11
Francke, U.12
Ramachandran, J.13
Fujita-Yamaguchi, Y.14
-
83
-
-
37249047933
-
Structural insights into ligand-induced activation of the insulin receptor
-
Ward, C., Lawrence, M., Streltsov, V., Garrett, T., McKern, N., Lou, M. Z., Lovrecz, G., and Adams, T. (2008). Structural insights into ligand-induced activation of the insulin receptor. Acta Physiol. (Oxf.) 192, 3-9.
-
(2008)
Acta Physiol. (Oxf. )
, vol.192
, pp. 3-9
-
-
Ward, C.1
Lawrence, M.2
Streltsov, V.3
Garrett, T.4
McKern, N.5
Lou, M.Z.6
Lovrecz, G.7
Adams, T.8
-
84
-
-
0029958903
-
Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor
-
Ward, C. W., Gough, K. H., Rashke, M., Wan, S. S., Tribbick, G., and Wang, J. (1996). Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor. J. Biol. Chem. 271, 5603-5609.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5603-5609
-
-
Ward, C.W.1
Gough, K.H.2
Rashke, M.3
Wan, S.S.4
Tribbick, G.5
Wang, J.6
-
85
-
-
0029060529
-
Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor
-
Ward, C. W., Hoyne, P. A., and Flegg, R. H. (1995). Insulin and epidermal growth factor receptors contain the cysteine repeat motif found in the tumor necrosis factor receptor. Proteins 22,141-153.
-
(1995)
Proteins
, vol.22
, pp. 141-153
-
-
Ward, C.W.1
Hoyne, P.A.2
Flegg, R.H.3
-
86
-
-
65449168837
-
Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor
-
Ward, C. W., and Lawrence, M. C. (2009). Ligand-induced activation of the insulin receptor: a multi-step process involving structural changes in both the ligand and the receptor. Bioessays 31, 422-434.
-
(2009)
Bioessays
, vol.31
, pp. 422-434
-
-
Ward, C.W.1
Lawrence, M.C.2
-
87
-
-
33847619358
-
The insulin and EGF receptor structures: new insights into ligand-induced receptor activation
-
Ward, C. W., Lawrence, M. C., Streltsov, V. A., Adams, T. E., and McKern, N. M. (2007). The insulin and EGF receptor structures: new insights into ligand-induced receptor activation. Trends Biochem. Sci. 32, 129-137.
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 129-137
-
-
Ward, C.W.1
Lawrence, M.C.2
Streltsov, V.A.3
Adams, T.E.4
McKern, N.M.5
-
88
-
-
61349161850
-
The structure and function of insulin decoding the TR transition
-
Weiss, M. A. (2009). The structure and function of insulin decoding the TR transition. Vitam. Horm. 80, 33-49.
-
(2009)
Vitam. Horm.
, vol.80
, pp. 33-49
-
-
Weiss, M.A.1
-
89
-
-
0022347547
-
Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185
-
White, M. F., Maron, R., and Kahn, C. R. (1985). Insulin rapidly stimulates tyrosine phosphorylation of a Mr-185,000 protein in intact cells. Nature 318, 183-186.
-
(1985)
000 protein in intact cells. Nature
, vol.318
, pp. 183-186
-
-
White, M.F.1
Maron, R.2
Kahn, C.R.3
-
90
-
-
0028874953
-
PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities
-
Wolf, G., Trub, T., Ottinger, E., Groninga, L., Lynch, A., White, M. F., Miyazaki, M., Lee, J., and Shoel-son, S. E. (1995). PTB domains of IRS-1 and Shc have distinct but overlapping binding specificities. J. Biol. Chem. 270,27407-27410.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 27407-27410
-
-
Wolf, G.1
Trub, T.2
Ottinger, E.3
Groninga, L.4
Lynch, A.5
White, M.F.6
Miyazaki, M.7
Lee, J.8
Shoel-son, S.E.9
-
91
-
-
3142579218
-
Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor
-
Xu, B., Hu, S. Q., Chu, Y C, Huang, K., Nakagawa, S. H., Whittaker, J., Katsoyannis, P. G., and Weiss, M. A. (2004). Diabetes-associated mutations in insulin: consecutive residues in the B chain contact distinct domains of the insulin receptor. Biochemistry 43, 8356-8372.
-
(2004)
Biochemistry
, vol.43
, pp. 8356-8372
-
-
Xu, B.1
Hu, S.Q.2
Chu, Y.C.3
Huang, K.4
Nakagawa, S.H.5
Whittaker, J.6
Katsoyannis, P.G.7
Weiss, M.A.8
-
92
-
-
67649827251
-
Decoding the cryptic active conformation of a protein by synthetic photo-scanningInsulin inserts a detachable arm between receptor domains
-
Xu, B., Huang, K., Chu, Y. C., Hu, S. Q., Nakagawa, S., Wang, S., Wang, R. Y., Whittaker, J., Katsoyannis, P. G., and Weiss, M. A. (2009). Decoding the cryptic active conformation of a protein by synthetic photo-scanning. Insulin inserts a detachable arm between receptor domains. J. Biol Chem. 284,14597-14608
-
(2009)
J. Biol Chem.
, vol.284
, pp. 14597-14608
-
-
Xu, B.1
Huang, K.2
Chu, Y.C.3
Hu, S.Q.4
Nakagawa, S.5
Wang, S.6
Wang, R.Y.7
Whittaker, J.8
Katsoyannis, P.G.9
Weiss, M.A.10
|