Direct determination of the insulin - insulin receptor interface using transferred cross-saturation experiments

Journal of Medicinal Chemistry

Volumn 53, Issue 5, 2010, Pages 1917-1922

  Nakamura, Takefumi ^a,b,c   Takahashi, Hideo ^c   Takahashi, Mitsuo ^a   Shimba, Nobuhisa ^a,b,c   Suzuki, Ei Ichiro ^a,b   Shimada, Ichio ^c,d  

^a AJINOMOTO CO INC   (Japan)

^b Japan Biological Informatics Consortium   (Japan)

^c NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; INSULIN RECEPTOR;

ARTICLE; BINDING SITE; CARBON NUCLEAR MAGNETIC RESONANCE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; EXPERIMENTAL STUDY; METABOLIC REGULATION; MUTATIONAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING; STRUCTURE ANALYSIS; TARGET CELL;

AMINO ACID SEQUENCE; BINDING SITES; BINDING, COMPETITIVE; INSULIN; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; RECEPTOR, INSULIN; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77949386271     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm901099v     Document Type: Article

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