-
1
-
-
57949116437
-
Dna-pk: The means to justify the ends?
-
PMID:19117531
-
Meek K, Dang V, Lees-Miller SP. DNA-PK: the means to justify the ends? Adv Immunol 2008; 99:33-58; PMID:19117531; http://dx.doi.org/10.1016/S0065- 2776(08)00602-0.
-
(2008)
Adv Immunol
, vol.99
, pp. 33-58
-
-
Meek, K.1
Dang, V.2
Lees-Miller, S.P.3
-
2
-
-
15844394846
-
Conserved modes of recruitment of atm, atr and dna-pkcs to sites of dna damage
-
PMID:15758953
-
Falck J, Coates J, Jackson SP. Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature 2005; 434:605-11; PMID:15758953; http://dx.doi.org/10.1038/nature03442.
-
(2005)
Nature
, vol.434
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
3
-
-
61649093808
-
Single-stranded dna orchestrates an atm-to-Atr switch at dna breaks
-
PMID:19285939
-
Shiotani B, Zou L. Single-stranded DNA orchestrates an ATM-to-ATR switch at DNA breaks. Mol Cell 2009; 33:547-58; PMID:19285939; http://dx.doi.org/10. 1016/j.molcel.2009.01.024.
-
(2009)
Mol Cell
, vol.33
, pp. 547-558
-
-
Shiotani, B.1
Zou, L.2
-
4
-
-
0037472924
-
Dna damage activates atm through intermolecular autophosphorylation and dimer dissociation
-
PMID:12556884
-
Bakkenist CJ, Kastan MB. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 2003; 421:499-506; PMID:12556884; http://dx.doi.org/10.1038/nature01368.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
5
-
-
84865364870
-
Playing the end game: Dna double-strand break repair pathway choice
-
PMID:22920291
-
Chapman JR, Taylor MR, Boulton SJ. Playing the end game: DNA double-strand break repair pathway choice. Mol Cell 2012; 47:497-510; PMID:22920291; http://dx.doi.org/10.1016/j.molcel.2012.07.029.
-
(2012)
Mol Cell
, vol.47
, pp. 497-510
-
-
Chapman, J.R.1
Taylor, M.R.2
Boulton, S.J.3
-
6
-
-
34250813133
-
Atmin defines an nbs1-independent pathway of atm signalling
-
PMID:17525732
-
Kanu N, Behrens A. ATMIN defines an NBS1-independent pathway of ATM signalling. EMBO J 2007; 26:2933-41; PMID:17525732; http://dx.doi.org/10.1038/ sj.emboj.7601733.
-
(2007)
EMBO J
, vol.26
, Issue.29
, pp. 33-41
-
-
Kanu, N.1
Behrens, A.2
-
7
-
-
30344463835
-
Atm-And cell cycle-dependent regulation of atr in response to dna double-strand breaks
-
PMID:16327781
-
Jazayeri A, Falck J, Lukas C, Bartek J, Smith GCM, Lukas J, et al. ATM-And cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat Cell Biol 2006; 8:37-45; PMID:16327781; http://dx.doi.org/10.1038/ ncb1337.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.M.5
Lukas, J.6
-
8
-
-
0020639045
-
Effect of ionizing radiation on synthesis of sub-replicon size dna in ataxia telangiectasia cells
-
PMID:6679327
-
Houldsworth J, Lavin MF. Effect of ionizing radiation on synthesis of sub-replicon size DNA in ataxia telangiectasia cells. Biochem Int 1983; 6:349-56; PMID:6679327.
-
(1983)
Biochem Int
, vol.6
, pp. 349-356
-
-
Houldsworth, J.1
Lavin, M.F.2
-
9
-
-
79953183356
-
Autophosphorylation and atm activation: Additional sites add to the complexity
-
PMID:21149446
-
Kozlov SV, Graham ME, Jakob B, Tobias F, Kijas AW, Tanuji M, et al. Autophosphorylation and ATM activation: additional sites add to the complexity. J Biol Chem 2011; 286:9107-19; PMID:21149446; http://dx.doi.org/10.1074/jbc. M110.204065.
-
(2011)
J Biol Chem
, vol.286
, pp. 9107-9119
-
-
Kozlov, S.V.1
Graham, M.E.2
Jakob, B.3
Tobias, F.4
Kijas, A.W.5
Tanuji, M.6
-
10
-
-
77958191599
-
Atm activation by oxidative stress
-
PMID:20966255
-
Guo Z, Kozlov S, Lavin MF, Person MD, Paull TT. ATM activation by oxidative stress. Science 2010; 330:517-21; PMID:20966255; http://dx.doi.org/10. 1126/science.1192912.
-
(2010)
Science
, vol.330
, Issue.5
, pp. 17-21
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
11
-
-
79957690359
-
Atr signalling: More than meeting at the fork
-
536; PMID:21615334
-
Nam EA, Cortez D. ATR signalling: more than meeting at the fork. Biochem J 2011; 436:527-36; PMID:21615334; http://dx.doi.org/10.1042/BJ20102162.
-
(2011)
Biochem J
, vol.436
, pp. 527-436
-
-
Nam, E.A.1
Cortez, D.2
-
12
-
-
24744448894
-
Atrip oligomerization is required for atr-dependent checkpoint signaling
-
PMID:16027118
-
Ball HL, Cortez D. ATRIP oligomerization is required for ATR-dependent checkpoint signaling. J Biol Chem 2005; 280:31390-6; PMID:16027118; http://dx.doi.org/10.1074/jbc.M504961200.
-
(2005)
J Biol Chem
, vol.280
, pp. 31390-313906
-
-
Ball, H.L.1
Cortez, D.2
-
13
-
-
80051678503
-
Thr 1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and rad3-related (atr) kinase
-
PMID:21705319
-
Nam EA, Zhao R, Glick GG, Bansbach CE, Friedman DB, Cortez D. Thr-1989 phosphorylation is a marker of active ataxia telangiectasia-mutated and Rad3-related (ATR) kinase. J Biol Chem 2011; 286:28707-14; PMID:21705319; http://dx.doi.org/10.1074/jbc. M111.248914.
-
(2011)
J Biol Chem
, vol.286
, pp. 28707-28714
-
-
Nam, E.A.1
Zhao, R.2
Glick, G.G.3
Bansbach, C.E.4
Friedman, D.B.5
Cortez, D.6
-
14
-
-
79957506234
-
Coordination of dna-pk activation and nuclease processing of dna termini in nhej
-
PMID:20698792
-
Pawelczak KS, Bennett SM, Turchi JJ. Coordination of DNA-PK activation and nuclease processing of DNA termini in NHEJ. Antioxid Redox Signal 2011; 14:2531-43; PMID:20698792; http://dx.doi.org/10.1089/ars.2010.3368.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 2531-2543
-
-
Pawelczak, K.S.1
Bennett, S.M.2
Turchi, J.J.3
-
15
-
-
46649102827
-
Interplay of two major repair pathways in the processing of complex double-strand dna breaks
-
PMID:18571480
-
Dobbs TA, Palmer P, Maniou Z, Lomax ME, O'Neill P. Interplay of two major repair pathways in the processing of complex double-strand DNA breaks. DNA Repair (Amst) 2008; 7:1372-83; PMID:18571480; http://dx.doi.org/10.1016/j. dnarep.2008.05.001.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 1372-1383
-
-
Dobbs, T.A.1
Palmer, P.2
Maniou, Z.3
Lomax, M.E.4
O'Neill, P.5
-
16
-
-
0032933430
-
The c terminus of ku80 activates the dna-dependent protein kinase catalytic subunit
-
PMID:10207052
-
Singleton BK, Torres-Arzayus MI, Rottinghaus ST, Taccioli GE, Jeggo PA. The C terminus of Ku80 activates the DNA-dependent protein kinase catalytic subunit. Mol Cell Biol 1999; 19:3267-77; PMID:10207052.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3267-3277
-
-
Singleton, B.K.1
Torres-Arzayus, M.I.2
Rottinghaus, S.T.3
Taccioli, G.E.4
Jeggo, P.A.5
-
17
-
-
0033198709
-
Mapping of protein-protein interactions within the dna-dependent protein kinase complex
-
PMID:10446239
-
Gell D, Jackson SP. Mapping of protein-protein interactions within the DNA-dependent protein kinase complex. Nucleic Acids Res 1999; 27:3494-502; PMID:10446239; http://dx.doi.org/10.1093/nar/27.17.3494.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 3494-3502
-
-
Gell, D.1
Jackson, S.P.2
-
18
-
-
61749092799
-
The ku80 carboxy terminus stimulates joining and artemis-mediated processing of dna ends
-
PMID:19103741
-
Weterings E, Verkaik NS, Keijzers G, Florea BI, Wang SY, Ortega LG, et al. The Ku80 carboxy terminus stimulates joining and artemis-mediated processing of DNA ends. Mol Cell Biol 2009; 29:1134-42; PMID:19103741; http://dx.doi.org/10.1128/MCB.00971-08.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 1134-1142
-
-
Weterings, E.1
Verkaik, N.S.2
Keijzers, G.3
Florea, B.I.4
Wang, S.Y.5
Ortega, L.G.6
-
19
-
-
84859707835
-
Multiple protein-protein interactions within the dna-pk complex are mediated by the c-terminus of ku 80
-
PMID:22509479
-
Bennett SM, Woods DS, Pawelczak KS, Turchi JJ. Multiple protein-protein interactions within the DNA-PK complex are mediated by the C-terminus of Ku 80. Int J Biochem Mol Biol 2012; 3:36-45; PMID:22509479.
-
(2012)
Int J Biochem Mol Biol
, vol.3
, pp. 36-45
-
-
Bennett, S.M.1
Woods, D.S.2
Pawelczak, K.S.3
Turchi, J.J.4
-
20
-
-
74049134920
-
Ku and dna-dependent protein kinase dynamic conformations and assembly regulate dna binding and the initial non-homologous end joining complex
-
PMID:19893054
-
Hammel M, Yu Y, Mahaney BL, Cai B, Ye R, Phipps BM, et al. Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem 2010; 285:1414-23; PMID:19893054; http://dx.doi.org/10.1074/jbc. M109.065615.
-
(2010)
J Biol Chem
, vol.285
, pp. 1414-1423
-
-
Hammel, M.1
Yu, Y.2
Mahaney, B.L.3
Cai, B.4
Ye, R.5
Phipps, B.M.6
-
21
-
-
47249150241
-
A mechanism for dnapk activation requiring unique contributions from each strand of a dna terminus and implications for microhomology-mediated nonhomologous dna end joining
-
PMID:18515838
-
Pawelczak KS, Turchi JJ. A mechanism for DNAPK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining. Nucleic Acids Res 2008; 36:4022-31; PMID:18515838; http://dx.doi.org/10.1093/nar/gkn344.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 4022-4031
-
-
Pawelczak, K.S.1
Turchi, J.J.2
-
22
-
-
34248231265
-
Lees-miller sp. Trans autophosphorylation at dna-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining
-
PMID:17353268
-
Meek K, Douglas P, Cui X, Ding Q, Lees-Miller SP. trans Autophosphorylation at DNA-dependent protein kinase's two major autophosphorylation site clusters facilitates end processing but not end joining. Mol Cell Biol 2007; 27:3881-90; PMID:17353268; http://dx.doi.org/10. 1128/MCB.02366-06.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 3881-3890
-
-
Meek, K.1
Douglas, P.2
Cui, X.3
Ding, Q.4
-
23
-
-
79953134635
-
Inhibition of homologous recombination by dna-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation
-
1733; PMID:21300785
-
Neal JA, Dang V, Douglas P, Wold MS, Lees-Miller SP, Meek K. Inhibition of homologous recombination by DNA-dependent protein kinase requires kinase activity, is titratable, and is modulated by autophosphorylation. Mol Cell Biol 2011; 31:1719-33; PMID:21300785; http://dx.doi.org/10.1128/MCB.01298-10.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1719-1731
-
-
Neal, J.A.1
Dang, V.2
Douglas, P.3
Wold, M.S.4
Lees-Miller, S.P.5
Meek, K.6
-
24
-
-
34247507469
-
Ataxia telangiectasia mutated (atm) is essential for dna-pkcs phosphorylations at the thr-2609 cluster upon dna double strand break
-
PMID:17189255
-
Chen BP, Uematsu N, Kobayashi J, Lerenthal Y, Krempler A, Yajima H, et al. Ataxia telangiectasia mutated (ATM) is essential for DNA-PKcs phosphorylations at the Thr-2609 cluster upon DNA double strand break. J Biol Chem 2007; 282:6582-7; PMID:17189255; http://dx.doi.org/10.1074/jbc. M611605200.
-
(2007)
J Biol Chem
, vol.282
, pp. 6582-6587
-
-
Chen, B.P.1
Uematsu, N.2
Kobayashi, J.3
Lerenthal, Y.4
Krempler, A.5
Yajima, H.6
-
25
-
-
33749611701
-
Atr-dependent phosphorylation of dna-dependent protein kinase catalytic subunit in response to uv-induced replication stress
-
PMID:16908529
-
Yajima H, Lee KJ, Chen BP. ATR-dependent phosphorylation of DNA-dependent protein kinase catalytic subunit in response to UV-induced replication stress. Mol Cell Biol 2006; 26:7520-8; PMID:16908529; http://dx.doi.org/10.1128/MCB. 00048-06.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 7520-7528
-
-
Yajima, H.1
Lee, K.J.2
Chen, B.P.3
-
26
-
-
16444384872
-
Deficiency in the catalytic subunit of dna-dependent protein kinase causes down-regulation of atm
-
PMID:15753361
-
Peng Y, Woods RG, Beamish H, Ye R, Lees-Miller SP, Lavin MF, et al. Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM. Cancer Res 2005; 65:1670-7; PMID:15753361; http://dx.doi.org/10.1158/0008-5472.CAN-04-3451.
-
(2005)
Cancer Res
, vol.65
, pp. 1670-1677
-
-
Peng, Y.1
Woods, R.G.2
Beamish, H.3
Ye, R.4
Lees-Miller, S.P.5
Lavin, M.F.6
-
27
-
-
79953708229
-
Ctip and mrn promote non-homologous endjoining of etoposide-induced dna double-strand breaks in g1
-
2152; PMID:21087997
-
Quennet V, Beucher A, Barton O, Takeda S, Löbrich M. CtIP and MRN promote non-homologous endjoining of etoposide-induced DNA double-strand breaks in G1. Nucleic Acids Res 2011; 39:2144-52; PMID:21087997; http://dx.doi.org/10. 1093/nar/gkq1175.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. 2144-2139
-
-
Quennet, V.1
Beucher, A.2
Barton, O.3
Takeda, S.4
Löbrich, M.5
-
28
-
-
80053447704
-
Release of ku and mrn from dna ends by mre11 nuclease activity and ctp1 is required for homologous recombination repair of double-strand breaks
-
PMID:21931565
-
Langerak P, Mejia-Ramirez E, Limbo O, Russell P. Release of Ku and MRN from DNA ends by Mre11 nuclease activity and Ctp1 is required for homologous recombination repair of double-strand breaks. PLoS Genet 2011; 7:e1002271; PMID:21931565; http://dx.doi.org/10.1371/journal.pgen.1002271.
-
(2011)
PLoS Genet
, vol.7
-
-
Langerak, P.1
Mejia-Ramirez, E.2
Limbo, O.3
Russell, P.4
-
29
-
-
84857479924
-
Ner and ddr: Classical music with new instruments
-
PMID:22373527
-
Sertic S, Pizzi S, Lazzaro F, Plevani P, Muzi-Falconi M. NER and DDR: classical music with new instruments. Cell Cycle 2012; 11:668-74; PMID:22373527; http://dx.doi.org/10.4161/cc.11.4.19117.
-
(2012)
Cell Cycle
, vol.11
, pp. 668-674
-
-
Sertic, S.1
Pizzi, S.2
Lazzaro, F.3
Plevani, P.4
Muzi-Falconi, M.5
-
30
-
-
38049164275
-
Eukaryotic nucleotide excision repair: From understanding mechanisms to influencing biology
-
PMID:18166981
-
Shuck SC, Short EA, Turchi JJ. Eukaryotic nucleotide excision repair: from understanding mechanisms to influencing biology. Cell Res 2008; 18:64-72; PMID:18166981; http://dx.doi.org/10.1038/cr.2008.2.
-
(2008)
Cell Res
, vol.1
, pp. 864-872
-
-
Shuck, S.C.1
Short, E.A.2
Turchi, J.J.3
-
31
-
-
80051961183
-
Human exonuclease 1 connects nucleotide excision repair (ner) processing with checkpoint activation in response to uv irradiation
-
13652; PMID:21808022
-
Sertic S, Pizzi S, Cloney R, Lehmann AR, Marini F, Plevani P, et al. Human exonuclease 1 connects nucleotide excision repair (NER) processing with checkpoint activation in response to UV irradiation. Proc Natl Acad Sci U S A 2011; 108:13647-52; PMID:21808022; http://dx.doi.org/10.1073/pnas.1108547108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 13647-13108
-
-
Sertic, S.1
Pizzi, S.2
Cloney, R.3
Lehmann, A.R.4
Marini, F.5
Plevani, P.6
-
32
-
-
84862758175
-
New insights into the molecular and cellular functions of poly(adp-ribose) and parps
-
PMID:22713970
-
Gibson BA, Kraus WL. New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nat Rev Mol Cell Biol 2012; 13:411-24; PMID:22713970; http://dx.doi.org/10.1038/nrm3376.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 411-424
-
-
Gibson, B.A.1
Kraus, W.L.2
-
33
-
-
67749104769
-
The dna-damage response: New molecular insights and new approaches to cancer therapy
-
PMID:19442242
-
Jackson SP. The DNA-damage response: new molecular insights and new approaches to cancer therapy. Biochem Soc Trans 2009; 37:483-94; PMID:19442242; http://dx.doi.org/10.1042/BST0370483.
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 483-494
-
-
Jackson, S.P.1
-
34
-
-
80053555789
-
More than just a focus: The chromatin response to dna damage and its role in genome integrity maintenance
-
PMID:21968989
-
Lukas J, Lukas C, Bartek J. More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance. Nat Cell Biol 2011; 13:1161-9; PMID:21968989; http://dx.doi.org/10.1038/ncb2344.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 116-119
-
-
Lukas, J.1
Lukas, C.2
Bartek, J.3
-
35
-
-
80054972492
-
H2ax: Biomarker of damage or functional participant in dna repair all that glitters is not gold!
-
PMID:21883247
-
Cleaver JE. γH2Ax: biomarker of damage or functional participant in DNA repair "all that glitters is not gold!". Photochem Photobiol 2011; 87:1230-9; PMID:21883247; http://dx.doi.org/10.1111/j.1751-1097.2011. 00995.x.
-
(2011)
Photochem Photobiol
, vol.87
, pp. 1230-1239
-
-
Cleaver, J.E.1
-
36
-
-
9744220428
-
A pathway of double-strand break rejoining dependent upon atm, artemis, and proteins locating to gamma-h2ax foci
-
PMID:15574327
-
Riballo E, Kühne M, Rief N, Doherty A, Smith GCM, Recio MJ, et al. A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci. Mol Cell 2004; 16:715-24; PMID:15574327; http://dx.doi.org/10.1016/j.molcel.2004.10.029.
-
(2004)
Mol Cell
, vol.16
, pp. 715-724
-
-
Riballo, E.1
Kühne, M.2
Rief, N.3
Doherty, A.4
Smith, G.C.M.5
Recio, M.J.6
-
37
-
-
63849187827
-
Tyrosine dephosphorylation of h2ax modulates apoptosis and survival decisions
-
PMID:19234442
-
Cook PJ, Ju BG, Telese F, Wang X, Glass CK, Rosenfeld MG. Tyrosine dephosphorylation of H2AX modulates apoptosis and survival decisions. Nature 2009; 458:591-6; PMID:19234442; http://dx.doi.org/10.1038/nature07849.
-
(2009)
Nature
, vol.458
, pp. 591-596
-
-
Cook, P.J.1
Ju, B.G.2
Telese, F.3
Wang, X.4
Glass, C.K.5
Rosenfeld, M.G.6
-
38
-
-
77956187851
-
Mdc1: The art of keeping things in focus
-
PMID:20224865
-
Jungmichel S, Stucki M. MDC1: The art of keeping things in focus. Chromosoma 2010; 119:337-49; PMID:20224865; http://dx.doi.org/10.1007/s00412- 010-0266-9.
-
(2010)
Chromosoma
, vol.119
, pp. 337-349
-
-
Jungmichel, S.1
Stucki, M.2
-
39
-
-
13444273546
-
Dna repair: The importance of phosphorylating histone h2ax
-
PMID:15694301
-
Lowndes NF, Toh GW. DNA repair: the importance of phosphorylating histone H2AX. Curr Biol 2005; 15:R99-102; PMID:15694301; http://dx.doi.org/10.1016/j. cub.2005.01.029.
-
(2005)
Curr Biol
, vol.15
-
-
Lowndes, N.F.1
Toh, G.W.2
-
40
-
-
34547115962
-
Ataxia-telangiectasia mutated (atm)-dependent activation of atr occurs through phosphorylation of topbp1 by atm
-
PMID:17446169
-
Yoo HY, Kumagai A, Shevchenko A, Shevchenko A, Dunphy WG. Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM. J Biol Chem 2007; 282:17501-6; PMID:17446169; http://dx.doi.org/10.1074/jbc.M701770200.
-
(2007)
J Biol Chem
, vol.282
, pp. 17501-1756
-
-
Yoo, H.Y.1
Kumagai, A.2
Shevchenko, A.3
Shevchenko, A.4
Dunphy, W.G.5
-
41
-
-
77951028251
-
Targeted inhibition of replication protein a reveals cytotoxic activity synergy with chemotherapeutic dna-damaging agents and insight into cellular function
-
PMID:20395205
-
Shuck SC, Turchi JJ. Targeted inhibition of Replication Protein A reveals cytotoxic activity, synergy with chemotherapeutic DNA-damaging agents, and insight into cellular function. Cancer Res 2010; 70:3189-98; PMID:20395205; http://dx.doi.org/10.1158/0008-5472.CAN-09-3422.
-
(2010)
Cancer Res
, vol.70
, pp. 3189-3198
-
-
Shuck, S.C.1
Turchi, J.J.2
-
42
-
-
84868213765
-
Distinct roles for dna-pk, atm and atr in rpa phosphorylation and checkpoint activation in response to replication stress
-
PMID:22977173
-
Liu S, Opiyo SO, Manthey K, Glanzer JG, Ashley AK, Amerin C, et al. Distinct roles for DNA-PK, ATM and ATR in RPA phosphorylation and checkpoint activation in response to replication stress. Nucleic Acids Res 2012; 40:10780-94; PMID:22977173; http://dx.doi.org/10.1093/nar/gks849.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 10780-10794
-
-
Liu, S.1
Opiyo, S.O.2
Manthey, K.3
Glanzer, J.G.4
Ashley, A.K.5
Amerin, C.6
-
43
-
-
84877619314
-
Dna-pk atm and atr collaboratively regulate p53-rpa interaction to facilitate homologous recombination dna repair
-
PMID:22797063
-
Serrano MA, Li Z, Dangeti M, Musich PR, Patrick S, Roginskaya M, et al. DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair. Oncogene 2012; PMID:22797063; http://dx.doi.org/10.1038/onc.2012.257.
-
(2012)
Oncogene
-
-
Serrano, M.A.1
Li, Z.2
Dangeti, M.3
Musich, P.R.4
Patrick, S.5
Roginskaya, M.6
-
44
-
-
79959488298
-
Dna-pk-dependent rpa2 hyperphosphorylation facilitates dna repair and suppresses sister chromatid exchange
-
PMID:21731742
-
Liaw H, Lee D, Myung K. DNA-PK-dependent RPA2 hyperphosphorylation facilitates DNA repair and suppresses sister chromatid exchange. PLoS One 2011; 6:e21424; PMID:21731742; http://dx.doi.org/10.1371/journal.pone.0021424.
-
(2011)
PLoS One
, vol.6
-
-
Liaw, H.1
Lee, D.2
Myung, K.3
-
45
-
-
70350540470
-
Protein phosphatase 2a-dependent dephosphorylation of replication protein a is required for the repair of dna breaks induced by replication stress
-
PMID:19704001
-
Feng J, Wakeman T, Yong S, Wu X, Kornbluth S, Wang XF. Protein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stress. Mol Cell Biol 2009; 29:5696-709; PMID:19704001; http://dx.doi.org/10.1128/MCB.00191-09.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5696-709
-
-
Feng, J.1
Wakeman, T.2
Yong, S.3
Wu, X.4
Kornbluth, S.5
Wang, X.F.6
-
46
-
-
79952454660
-
Atr: A master conductor of cellular responses to dna replication stress
-
PMID:20947357
-
Flynn RL, Zou L. ATR: a master conductor of cellular responses to DNA replication stress. Trends Biochem Sci 2011; 36:133-40; PMID:20947357; http://dx.doi.org/10.1016/j.tibs.2010.09.005.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 133-140
-
-
Flynn, R.L.1
Zou, L.2
-
47
-
-
33746408535
-
Rad17 phosphorylation is required for claspin recruitment and chk1 activation in response to replication stress
-
PMID:16885023
-
Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, et al. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell 2006; 23:331-41; PMID:16885023; http://dx.doi.org/10.1016/j.molcel. 2006.06.022.
-
(2006)
Mol Cell
, vol.23
, pp. 331-341
-
-
Wang, X.1
Zou, L.2
Lu, T.3
Bao, S.4
Hurov, K.E.5
Hittelman, W.N.6
-
48
-
-
63749131243
-
Kinases that control the cell cycle in response to dna damage: Chk1, chk2, and mk2
-
PMID:19230643
-
Reinhardt HC, Yaffe MB. Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2. Curr Opin Cell Biol 2009; 21:245-55; PMID:19230643; http://dx.doi.org/10.1016/j.ceb.2009.01.018.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 245-255
-
-
Reinhardt, H.C.1
Yaffe, M.B.2
-
49
-
-
0034326802
-
Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of chk2 in response to ionizing radiation
-
PMID:11085506
-
Ahn JY, Schwarz JK, Piwnica-Worms H, Canman CE. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res 2000; 60:5934-6; PMID:11085506.
-
(2000)
Cancer Res
, vol.60
, pp. 5934-5936
-
-
Ahn, J.Y.1
Schwarz, J.K.2
Piwnica-Worms, H.3
Canman, C.E.4
-
50
-
-
3242884449
-
The chk2 protein kinase
-
PMID:15279791
-
Ahn J, Urist M, Prives C. The Chk2 protein kinase. DNA Repair (Amst) 2004; 3:1039-47; PMID:15279791; http://dx.doi.org/10.1016/j.dnarep.2004.03.033.
-
(2004)
DNA Repair (Amst)
, vol.3
, pp. 1039-1047
-
-
Ahn, J.1
Urist, M.2
Prives, C.3
-
51
-
-
50349103243
-
Differential roles for checkpoint kinases in dna damage-dependent degradation of the cdc25a protein phosphatase
-
PMID:18480045
-
Jin J, Ang XL, Ye X, Livingstone M, Harper JW. Differential roles for checkpoint kinases in DNA damage-dependent degradation of the Cdc25A protein phosphatase. J Biol Chem 2008; 283:19322-8; PMID:18480045; http://dx.doi.org/10. 1074/jbc. M802474200.
-
(2008)
J Biol Chem
, vol.283
, pp. 19322-1938
-
-
Jin, J.1
Ang, X.L.2
Ye, X.3
Livingstone, M.4
Harper, J.W.5
-
52
-
-
0347361537
-
Scfbeta-trcp links chk1 signaling to degradation of the cdc25a protein phosphatase
-
PMID:14681206
-
Jin J, Shirogane T, Xu L, Nalepa G, Qin J, Elledge SJ, et al. SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase. Genes Dev 2003; 17:3062-74; PMID:14681206; http://dx.doi.org/10. 1101/gad.1157503.
-
(2003)
Genes Dev
, vol.17
, pp. 3062-3074
-
-
Jin, J.1
Shirogane, T.2
Xu, L.3
Nalepa, G.4
Qin, J.5
Elledge, S.J.6
-
53
-
-
15044365805
-
Normal cell cycle and checkpoint responses in mice and cells lacking cdc25b and cdc25c protein phosphatases
-
PMID:15767688
-
Ferguson AM, White LS, Donovan PJ, Piwnica-Worms H. Normal cell cycle and checkpoint responses in mice and cells lacking Cdc25B and Cdc25C protein phosphatases. Mol Cell Biol 2005; 25:2853-60; PMID:15767688; http://dx.doi.org/10.1128/MCB.25.7.2853-2860.2005.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 2853-2860
-
-
Ferguson, A.M.1
White, L.S.2
Donovan, P.J.3
Piwnica-Worms, H.4
-
54
-
-
84863606096
-
Chk2 phosphorylation of survivin-deltaex3 contributes to a dna damage-sensing checkpoint in cancer
-
PMID:22586065
-
Lopergolo A, Tavecchio M, Lisanti S, Ghosh JC, Dohi T, Faversani A, et al. Chk2 phosphorylation of survivin-DeltaEx3 contributes to a DNA damage-sensing checkpoint in cancer. Cancer Res 2012; 72:3251-9; PMID:22586065; http://dx.doi.org/10.1158/0008-5472.CAN-11-4035.
-
(2012)
Cancer Res
, vol.72
, pp. 3251-3259
-
-
Lopergolo, A.1
Tavecchio, M.2
Lisanti, S.3
Ghosh, J.C.4
Dohi, T.5
Faversani, A.6
-
55
-
-
84865188025
-
Checkpoint kinase 2 (chk2) inhibits the activity of the cdc45/mcm2-7/gins (cmg) replicative helicase complex
-
PMID:22853956
-
Ilves I, Tamberg N, Botchan MR. Checkpoint kinase 2 (Chk2) inhibits the activity of the Cdc45/MCM2-7/GINS (CMG) replicative helicase complex. Proc Natl Acad Sci U S A 2012; 109:13163-70; PMID:22853956; http://dx.doi.org/10.1073/ pnas.1211525109.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13163-13170
-
-
Ilves, I.1
Tamberg, N.2
Botchan, M.R.3
-
56
-
-
84861974796
-
The intra-s phase checkpoint targets dna2 to prevent stalled replication forks from reversing
-
PMID:22682245
-
Hu J, Sun L, Shen F, Chen Y, Hua Y, Liu Y, et al. The intra-S phase checkpoint targets Dna2 to prevent stalled replication forks from reversing. Cell 2012; 149:1221-32; PMID:22682245; http://dx.doi.org/10.1016/j.cell.2012.04. 030.
-
(2012)
Cell
, vol.149
, pp. 1221-1232
-
-
Hu, J.1
Sun, L.2
Shen, F.3
Chen, Y.4
Hua, Y.5
Liu, Y.6
-
58
-
-
40749085662
-
Bendamustine (treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents
-
PMID:18172283
-
Leoni LM, Bailey B, Reifert J, Bendall HH, Zeller RW, Corbeil J, et al. Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents. Clin Cancer Res 2008; 14:309-17; PMID:18172283; http://dx.doi.org/10.1158/1078-0432.CCR-07-1061.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 309-317
-
-
Leoni, L.M.1
Bailey, B.2
Reifert, J.3
Bendall, H.H.4
Zeller, R.W.5
Corbeil, J.6
-
59
-
-
0015520267
-
Investigation of crosslink formation in dna by the alkylating cytostatic imet 3106, 3393 and 3943
-
PMID:4629776
-
Hartmann M, Zimmer C. Investigation of crosslink formation in DNA by the alkylating cytostatic IMET 3106, 3393 and 3943. Biochim Biophys Acta 1972; 287:386-9; PMID:4629776; http://dx.doi.org/10.1016/0005-2787(72)90282-1.
-
(1972)
Biochim Biophys Acta
, vol.287
, pp. 386-389
-
-
Hartmann, M.1
Zimmer, C.2
-
60
-
-
0030005440
-
Bendamustine hydrochloride activity against doxorubicin-resistant human breast carcinoma cell lines
-
PMID:8826610
-
Strumberg D, Harstrick A, Doll K, Hoffmann B, Seeber S. Bendamustine hydrochloride activity against doxorubicin-resistant human breast carcinoma cell lines. Anticancer Drugs 1996; 7:415-21; PMID:8826610; http://dx.doi.org/10. 1097/00001813-199606000-00007.
-
(1996)
Anticancer Drugs
, vol.7
, pp. 415-421
-
-
Strumberg, D.1
Harstrick, A.2
Doll, K.3
Hoffmann, B.4
Seeber, S.5
-
61
-
-
66249147593
-
Association between transcriptional activity local chromatin structure and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts
-
PMID:19417135
-
Episkopou H, Kyrtopoulos SA, Sfikakis PP, Fousteri M, Dimopoulos MA, Mullenders LH, et al. Association between transcriptional activity, local chromatin structure, and the efficiencies of both subpathways of nucleotide excision repair of melphalan adducts. Cancer Res 2009; 69:4424-33; PMID:19417135; http://dx.doi.org/10.1158/0008-5472.CAN-08-3489.
-
(2009)
Cancer Res
, vol.69
, pp. 4424-4433
-
-
Episkopou, H.1
Kyrtopoulos, S.A.2
Sfikakis, P.P.3
Fousteri, M.4
Dimopoulos, M.A.5
Mullenders, L.H.6
-
62
-
-
36849037354
-
Bendamustine induces g2 cell cycle arrest and apoptosis in myeloma cells: The role of atmchk2-cdc25a and atm-p53-p21-pathways
-
PMID:17653574; http://dx.doi.org/10.1007/s00432-007-0278-x.
-
Gaul L, Mandl-Weber S, Baumann P, Emmerich B, Schmidmaier R. Bendamustine induces G2 cell cycle arrest and apoptosis in myeloma cells: the role of ATMChk2-Cdc25A and ATM-p53-p21-pathways. J Cancer Res Clin Oncol 2008; 134:245-53; PMID:17653574; http://dx.doi.org/10.1007/s00432-007-0278-x.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 245-253
-
-
Gaul, L.1
Mandl-Weber, S.2
Baumann, P.3
Emmerich, B.4
Schmidmaier, R.5
-
63
-
-
84864877535
-
The checkpoint kinase inhibitor azd7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells
-
PMID:22653969
-
Landau HJ, McNeely SC, Nair JS, Comenzo RL, Asai T, Friedman H, et al. The checkpoint kinase inhibitor AZD7762 potentiates chemotherapy-induced apoptosis of p53-mutated multiple myeloma cells. Mol Cancer Ther 2012; 11:1781-8; PMID:22653969; http://dx.doi.org/10.1158/1535-7163.MCT-11-0949.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 1781-1788
-
-
Landau, H.J.1
McNeely, S.C.2
Nair, J.S.3
Comenzo, R.L.4
Asai, T.5
Friedman, H.6
-
64
-
-
84863098001
-
Dose dependent effects on cell cycle checkpoints and dna repair by bendamustine
-
PMID:22768280
-
Beeharry N, Rattner JB, Bellacosa A, Smith MR, Yen TJ. Dose dependent effects on cell cycle checkpoints and DNA repair by bendamustine. PLoS One 2012; 7:e40342; PMID:22768280; http://dx.doi.org/10.1371/journal.pone.0040342.
-
(2012)
PLoS One
, vol.7
-
-
Beeharry, N.1
Rattner, J.B.2
Bellacosa, A.3
Smith, M.R.4
Yen, T.J.5
-
65
-
-
81255138410
-
Dna repair: From genome maintenance to biomarker and therapeutic target
-
PMID:21908578
-
Jalal S, Earley JN, Turchi JJ. DNA repair: from genome maintenance to biomarker and therapeutic target. Clin Cancer Res 2011; 17:6973-84; PMID:21908578; http://dx.doi.org/10.1158/1078-0432.CCR-11-0761.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 6973-6984
-
-
Jalal, S.1
Earley, J.N.2
Turchi, J.J.3
-
66
-
-
40849114493
-
Enhanced dna-pk-mediated rpa2 hyperphosphorylation in dna polymerase eta-deficient human cells treated with cisplatin and oxaliplatin
-
PMID:18289945
-
Cruet-Hennequart S, Glynn MT, Murillo LS, Coyne S, Carty MP. Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin. DNA Repair (Amst) 2008; 7:582-96; PMID:18289945; http://dx.doi.org/10.1016/j.dnarep.2007.12.012.
-
(2008)
DNA Repair (Amst)
, vol.7
, pp. 582-596
-
-
Cruet-Hennequart, S.1
Glynn, M.T.2
Murillo, L.S.3
Coyne, S.4
Carty, M.P.5
-
67
-
-
44249118962
-
Atrchk2 signaling in p53 activation and dna damage response during cisplatin-induced apoptosis
-
PMID:18162465
-
Pabla N, Huang S, Mi QS, Daniel R, Dong Z. ATRChk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis. J Biol Chem 2008; 283:6572-83; PMID:18162465; http://dx.doi.org/10.1074/jbc.M707568200.
-
(2008)
J Biol Chem
, vol.283
, pp. 6572-6583
-
-
Pabla, N.1
Huang, S.2
Mi, Q.S.3
Daniel, R.4
Dong, Z.5
-
68
-
-
33748754078
-
The involvement of ataxia-telangiectasia mutated protein activation in nucleotide excision repair-facilitated cell survival with cisplatin treatment
-
PMID:16849332
-
Colton SL, Xu XS, Wang YA, Wang G. The involvement of ataxia-telangiectasia mutated protein activation in nucleotide excision repair-facilitated cell survival with cisplatin treatment. J Biol Chem 2006; 281:27117-25; PMID:16849332; http://dx.doi.org/10.1074/jbc.M602826200.
-
(2006)
J Biol Chem
, vol.281
, pp. 27117-27125
-
-
Colton, S.L.1
Xu, X.S.2
Wang, Y.A.3
Wang, G.4
-
69
-
-
79957880430
-
Atr mediates cisplatin resistance in a p53 genotype-specific manner
-
2533; PMID:21258400
-
Sangster-Guity N, Conrad BH, Papadopoulos N, Bunz F. ATR mediates cisplatin resistance in a p53 genotype-specific manner. Oncogene 2011; 30:2526-33; PMID:21258400; http://dx.doi.org/10.1038/onc.2010.624.
-
(2011)
Oncogene
, vol.30
, pp. 2526-2530
-
-
Sangster-Guity, N.1
Conrad, B.H.2
Papadopoulos, N.3
Bunz, F.4
-
70
-
-
66449095927
-
Ataxia telangiectasia and rad3-related kinase contributes to cell cycle arrest and survival after cisplatin but not oxaliplatin
-
PMID:19372558
-
Lewis KA, Lilly KK, Reynolds EA, Sullivan WP, Kaufmann SH, Cliby WA. Ataxia telangiectasia and rad3-related kinase contributes to cell cycle arrest and survival after cisplatin but not oxaliplatin. Mol Cancer Ther 2009; 8:855-63; PMID:19372558; http://dx.doi.org/10.1158/1535-7163.MCT-08-1135.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 855-863
-
-
Lewis, K.A.1
Lilly, K.K.2
Reynolds, E.A.3
Sullivan, W.P.4
Kaufmann, S.H.5
Cliby, W.A.6
-
71
-
-
84865843265
-
The novel atr inhibitor ve-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy
-
PMID:22825331
-
Prevo R, Fokas E, Reaper PM, Charlton PA, Pollard JR, McKenna WG, et al. The novel ATR inhibitor VE-821 increases sensitivity of pancreatic cancer cells to radiation and chemotherapy. Cancer Biol Ther 2012; 13:1072-81; PMID:22825331; http://dx.doi.org/10.4161/cbt.21093.
-
(2012)
Cancer Biol Ther
, vol.13
, pp. 1072-1081
-
-
Prevo, R.1
Fokas, E.2
Reaper, P.M.3
Charlton, P.A.4
Pollard, J.R.5
McKenna, W.G.6
-
72
-
-
79960834396
-
Identification and evaluation of a potent novel atr inhibitor, nu6027, in breast and ovarian cancer cell lines
-
381; PMID:21730979
-
Peasland A, Wang LZ, Rowling E, Kyle S, Chen T, Hopkins A, et al. Identification and evaluation of a potent novel ATR inhibitor, NU6027, in breast and ovarian cancer cell lines. Br J Cancer 2011; 105:372-81; PMID:21730979; http://dx.doi.org/10.1038/bjc.2011.243.
-
(2011)
Br J Cancer
, vol.105
, pp. 372-105
-
-
Peasland, A.1
Wang, L.Z.2
Rowling, E.3
Kyle, S.4
Chen, T.5
Hopkins, A.6
-
73
-
-
0034967556
-
Atr-mediated checkpoint pathways regulate phosphorylation and activation of human chk1
-
PMID:11390642
-
Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 2001; 21:4129-39; PMID:11390642; http://dx.doi.org/10.1128/MCB.21.13.4129-4139.2001.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4129-4139
-
-
Zhao, H.1
Piwnica-Worms, H.2
-
74
-
-
16844366148
-
Review of ucn-01 development: A lesson in the importance of clinical pharmacology
-
PMID:15778420
-
Fuse E, Kuwabara T, Sparreboom A, Sausville EA, Figg WD. Review of UCN-01 development: a lesson in the importance of clinical pharmacology. J Clin Pharmacol 2005; 45:394-403; PMID:15778420; http://dx.doi.org/10.1177/ 0091270005274549.
-
(2005)
J Clin Pharmacol
, vol.45
, pp. 394-403
-
-
Fuse, E.1
Kuwabara, T.2
Sparreboom, A.3
Sausville, E.A.4
Figg, W.D.5
-
75
-
-
67649842315
-
Cisplatin-induced dna damage activates replication checkpoint signaling components that differentially affect tumor cell survival
-
PMID:19403702
-
Wagner JM, Karnitz LM. Cisplatin-induced DNA damage activates replication checkpoint signaling components that differentially affect tumor cell survival. Mol Pharmacol 2009; 76:208-14; PMID:19403702; http://dx.doi.org/10.1124/mol. 109.055178.
-
(2009)
Mol Pharmacol
, vol.76
, pp. 208-214
-
-
Wagner, J.M.1
Karnitz, L.M.2
-
76
-
-
0033801694
-
Basis for effective combination cancer chemotherapy with antimetabolites
-
PMID:11008002
-
Peters GJ, van der Wilt CL, van Moorsel CJ, Kroep JR, Bergman AM, Ackland SP. Basis for effective combination cancer chemotherapy with antimetabolites. Pharmacol Ther 2000; 87:227-53; PMID:11008002; http://dx.doi.org/10.1016/S0163- 7258(00)00086-3.
-
(2000)
Pharmacol Ther
, vol.87
, pp. 227-253
-
-
Peters, G.J.1
Van Der Wilt, C.L.2
Van Moorsel, C.J.3
Kroep, J.R.4
Bergman, A.M.5
Ackland, S.P.6
-
77
-
-
27844561114
-
Gemcitabine-induced activation of checkpoint signaling pathways that affect tumor cell survival
-
PMID:16126823
-
Karnitz LM, Flatten KS, Wagner JM, Loegering D, Hackbarth JS, Arlander SJ, et al. Gemcitabine-induced activation of checkpoint signaling pathways that affect tumor cell survival. Mol Pharmacol 2005; 68:1636-44; PMID:16126823.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 1636-1644
-
-
Karnitz, L.M.1
Flatten, K.S.2
Wagner, J.M.3
Loegering, D.4
Hackbarth, J.S.5
Arlander, S.J.6
-
78
-
-
84869074814
-
Rac1 protein signaling is required for dna damage response stimulated by topoisomerase ii poisons
-
PMID:23012366
-
Huelsenbeck SC, Schorr A, Roos WP, Huelsenbeck J, Henninger C, Kaina B, et al. Rac1 protein signaling is required for DNA damage response stimulated by topoisomerase II poisons. J Biol Chem 2012; 287:38590-9; PMID:23012366; http://dx.doi.org/10.1074/jbc.M112.377903.
-
(2012)
J Biol Chem
, vol.287
, pp. 38590-38599
-
-
Huelsenbeck, S.C.1
Schorr, A.2
Roos, W.P.3
Huelsenbeck, J.4
Henninger, C.5
Kaina, B.6
-
79
-
-
17144377827
-
The role of checkpoint kinase 1 in sensitivity to topoisomerase i poisons
-
PMID:15699047
-
Flatten K, Dai NT, Vroman BT, Loegering D, Erlichman C, Karnitz LM, et al. The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons. J Biol Chem 2005; 280:14349-55; PMID:15699047; http://dx.doi.org/10.1074/jbc. M411890200.
-
(2005)
J Biol Chem
, vol.280
, pp. 14349-14355
-
-
Flatten, K.1
Dai, N.T.2
Vroman, B.T.3
Loegering, D.4
Erlichman, C.5
Karnitz, L.M.6
-
80
-
-
33645235623
-
The radiomimetic enediyne c-1027 induces unusual dna damage responses to double-strand breaks
-
PMID:16533058
-
Kennedy DR, Beerman TA. The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks. Biochemistry 2006; 45:3747-54; PMID:16533058; http://dx.doi.org/10.1021/bi052334c.
-
(2006)
Biochemistry
, vol.45
, pp. 3747-3754
-
-
Kennedy, D.R.1
Beerman, T.A.2
-
81
-
-
36749074497
-
Designer enediynes generate dna breaks, interstrand crosslinks, or both, with concomitant changes in the regulation of dna damage responses
-
PMID:17978180
-
Kennedy DR, Ju J, Shen B, Beerman TA. Designer enediynes generate DNA breaks, interstrand crosslinks, or both, with concomitant changes in the regulation of DNA damage responses. Proc Natl Acad Sci U S A 2007; 104:17632-7; PMID:17978180; http://dx.doi.org/10.1073/pnas.0708274104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 17632-1767
-
-
Kennedy, D.R.1
Ju, J.2
Shen, B.3
Beerman, T.A.4
|