The radiomimetic enediyne C-1027 induces unusual DNA damage responses to double-strand breaks

Biochemistry

Volumn 45, Issue 11, 2006, Pages 3747-3754

  Kennedy, Daniel R ^a   Beerman, Terry A ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; DNA; IONIZATION; MOLECULAR DYNAMICS; RADIATION;

ATAXIA TELANGIECTASIA MUTATED (ATM); DOUBLE-STRAND BREAKS (DSB); PHOSPHORYLATION; RADIOMIMETICS;

ENZYMES;

ALKENYLDIALKYNE DERIVATIVE; ANTIBIOTIC C 1027; ATM PROTEIN; ATR PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; PROTEIN P53; SERINE; UNCLASSIFIED DRUG; ZINOSTATIN;

ARTICLE; CELL CYCLE; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INFRARED RADIATION; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMINO ACIDS, CYCLIC; AMINOGLYCOSIDES; ANTIBIOTICS, ANTINEOPLASTIC; CELL CYCLE PROTEINS; CELL DEATH; CELLS, CULTURED; DNA DAMAGE; DNA-BINDING PROTEINS; ENEDIYNES; FIBROBLASTS; HUMANS; INFRARED RAYS; PHOSPHORYLATION; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; SERINE; THREONINE; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS; ZINOSTATIN;

ATAXIA TELANGIECTASIA;

EID: 33645235623     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi052334c     Document Type: Article

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