Designer enediynes generate DNA breaks, interstrand cross-links, or both, with concomitant changes in the regulation of DNA damage responses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 45, 2007, Pages 17632-17637

  Kennedy, Daniel R ^a   Ju, Jianhua ^b   Shen, Ben ^b   Beerman, Terry A ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

ATM; ATR; C 1027; DNA double strand break; Radioimetic

Indexed keywords

ANTIBIOTIC C 1027; ANTINEOPLASTIC AGENT; BENZOXAZOLE DERIVATIVE; CELL DNA; GENOMIC DNA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE;

ARTICLE; ATAXIA TELANGIECTASIA; CHROMATOPHORE; CONTROLLED STUDY; CROSS LINKING; DNA DAMAGE; DNA ISOLATION; DNA STRAND BREAKAGE; DRUG EFFECT; GEL ELECTROPHORESIS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IONIZING RADIATION; PRIORITY JOURNAL; SIMIAN VIRUS 40; VIRUS INFECTION;

ANTINEOPLASTIC AGENTS; ATAXIA TELANGIECTASIA; CROSS-LINKING REAGENTS; DNA; DNA DAMAGE; DNA, VIRAL; ENEDIYNES; GENE EXPRESSION REGULATION; HUMANS; KINETICS; MUTATION; NUCLEIC ACID CONFORMATION; PLASMIDS; SIMIAN VIRUS 40;

ATAXIA TELANGIECTASIA;

EID: 36749074497     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0708274104     Document Type: Article

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