-
1
-
-
68849092509
-
Impact of regulatory polymorphisms in organic anion transporter genes in the human liver
-
Aoki M, Terada T, Ogasawara K, Katsura T, Hatano E, Ikai I, and Inui K (2009) Impact of regulatory polymorphisms in organic anion transporter genes in the human liver. Pharmacogenet Genomics 19:647-656.
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 647-656
-
-
Aoki, M.1
Terada, T.2
Ogasawara, K.3
Katsura, T.4
Hatano, E.5
Ikai, I.6
Inui, K.7
-
2
-
-
75449100306
-
Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays
-
Bolotin E, Liao H, Ta TC, Yang C, Hwang-Verslues W, Evans JR, Jiang T, and Sladek FM (2010) Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays. Hepatology 51:642-653.
-
(2010)
Hepatology
, vol.51
, pp. 642-653
-
-
Bolotin, E.1
Liao, H.2
Ta, T.C.3
Yang, C.4
Hwang-Verslues, W.5
Evans, J.R.6
Jiang, T.7
Sladek, F.M.8
-
3
-
-
33747154772
-
Anatomical profiling of nuclear receptor expression revealsa hierarchical transcriptional network
-
DOI 10.1016/j.cell.2006.06.049, PII S0092867406009779
-
Bookout AL, Jeong Y, Downes M, Yu RT, Evans RM, and Mangelsdorf DJ (2006) Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell 126:789-799. (Pubitemid 44233630)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 789-799
-
-
Bookout, A.L.1
Jeong, Y.2
Downes, M.3
Yu, R.T.4
Evans, R.M.5
Mangelsdorf, D.J.6
-
4
-
-
0032793959
-
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
-
Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, and Kim RB (1999) OATP and Pglycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. Drug Metab Dispos 27:866-871. (Pubitemid 29347585)
-
(1999)
Drug Metabolism and Disposition
, vol.27
, Issue.8
, pp. 866-871
-
-
Cvetkovic, M.1
Leake, B.2
Fromm, M.F.3
Wilkinson, G.R.4
Kim, R.B.5
-
5
-
-
84863228237
-
Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors
-
Fang B, Mane-Padros D, Bolotin E, Jiang T, and Sladek FM (2012) Identification of a binding motif specific to HNF4 by comparative analysis of multiple nuclear receptors. Nucleic Acids Res 40:5343-5356.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 5343-5356
-
-
Fang, B.1
Mane-Padros, D.2
Bolotin, E.3
Jiang, T.4
Sladek, F.M.5
-
6
-
-
33845524038
-
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart
-
DOI 10.1016/j.clpt.2006.09.010, PII S0009923606003882
-
Grube M, Köck K, Oswald S, Draber K, Meissner K, Eckel L, Böhm M, Felix SB, Vogelgesang S, and Jedlitschky G et al. (2006) Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart. Clin Pharmacol Ther 80:607-620. (Pubitemid 44920223)
-
(2006)
Clinical Pharmacology and Therapeutics
, vol.80
, Issue.6
, pp. 607-620
-
-
Grube, M.1
Kock, K.2
Oswald, S.3
Draber, K.4
Meissner, K.5
Eckel, L.6
Bohm, M.7
Felix, S.B.8
Vogelgesang, S.9
Jedlitschky, G.10
Siegmund, W.11
Warzok, R.12
Kroemer, H.K.13
-
7
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/SLC21 family: Phylogenetic classification as OATP/SLCO super-family, new nomenclature and molecular/functional properties
-
DOI 10.1007/s00424-003-1168-y, The ABCs of Solute Carriers: Physiological, Pathological and Therapeutic Implications of Human Membrane Transport Proteins
-
Hagenbuch B and Meier PJ (2004) Organic anion transporting polypeptides of the OATP/ SLC21 family: Phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch 447:653-665. (Pubitemid 38241451)
-
(2004)
Pflugers Archiv European Journal of Physiology
, vol.447
, Issue.5
, pp. 653-665
-
-
Hagenbuch, B.1
Meier, P.J.2
-
8
-
-
33646536542
-
Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics
-
Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, and Kim RB (2006) Drug and bile acid transporters in rosuvastatin hepatic uptake: Function, expression, and pharmacogenetics. Gastroenterology 130:1793-1806.
-
(2006)
Gastroenterology
, vol.130
, pp. 1793-1806
-
-
Ho, R.H.1
Tirona, R.G.2
Leake, B.F.3
Glaeser, H.4
Lee, W.5
Lemke, C.J.6
Wang, Y.7
Kim, R.B.8
-
9
-
-
78149496291
-
HNF4a-role in drug metabolism and potential drug target?
-
Hwang-Verslues WW and Sladek FM (2010) HNF4a-role in drug metabolism and potential drug target? Curr Opin Pharmacol 10:698-705.
-
(2010)
Curr Opin Pharmacol
, vol.10
, pp. 698-705
-
-
Hwang-Verslues, W.W.1
Sladek, F.M.2
-
10
-
-
0035124052
-
Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting
-
DOI 10.1053/jhep.2001.22176
-
Jover R, Bort R, Gómez-Lechón MJ, and Castell JV (2001) Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targeting. Hepatology 33:668-675. (Pubitemid 32185230)
-
(2001)
Hepatology
, vol.33
, Issue.3
, pp. 668-675
-
-
Jover, R.1
Bort, R.2
Gomez-Lechon, M.J.3
Castell, J.V.4
-
11
-
-
70350771206
-
Transcriptional regulation of cytochrome p450 genes by the nuclear receptor hepatocyte nuclear factor 4-alpha
-
Jover R, Moya M, and Gómez-Lechón MJ (2009) Transcriptional regulation of cytochrome p450 genes by the nuclear receptor hepatocyte nuclear factor 4-alpha. Curr Drug Metab 10:508-519.
-
(2009)
Curr Drug Metab
, vol.10
, pp. 508-519
-
-
Jover, R.1
Moya, M.2
Gómez-Lechón, M.J.3
-
12
-
-
34848824067
-
Role of human hepatocyte nuclear factor 4alpha in the expression of drugmetabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA
-
Kamiyama Y, Matsubara T, Yoshinari K, Nagata K, Kamimura H, and Yamazoe Y (2007) Role of human hepatocyte nuclear factor 4alpha in the expression of drugmetabolizing enzymes and transporters in human hepatocytes assessed by use of small interfering RNA. Drug Metab Pharmacokinet 22:287-298.
-
(2007)
Drug Metab Pharmacokinet
, vol.22
, pp. 287-298
-
-
Kamiyama, Y.1
Matsubara, T.2
Yoshinari, K.3
Nagata, K.4
Kamimura, H.5
Yamazoe, Y.6
-
13
-
-
33646779923
-
Involvement of hepatocyte nuclear factor 4 in the different expression level between CYP2C9 and CYP2C19 in the human liver
-
DOI 10.1124/dmd.106.009365
-
Kawashima S, Kobayashi K, Takama K, Higuchi T, Furihata T, Hosokawa M, and Chiba K (2006) Involvement of hepatocyte nuclear factor 4alpha in the different expression level between CYP2C9 and CYP2C19 in the human liver. Drug Metab Dispos 34:1012-1018. (Pubitemid 43763759)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.6
, pp. 1012-1018
-
-
Kawashima, S.1
Kobayashi, K.2
Takama, K.3
Higuchi, T.4
Furihata, T.5
Hosokawa, M.6
Chiba, K.7
-
14
-
-
77956247876
-
PH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: Potential role in antiretroviral drug oral bioavailability and drug-drug interactions
-
Kis O, Zastre JA, Ramaswamy M, and Bendayan R (2010) pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: Potential role in antiretroviral drug oral bioavailability and drug-drug interactions. J Pharmacol Exp Ther 334:1009-1022.
-
(2010)
J Pharmacol Exp Ther
, vol.334
, pp. 1009-1022
-
-
Kis, O.1
Zastre, J.A.2
Ramaswamy, M.3
Bendayan, R.4
-
15
-
-
76349092662
-
Meyer zu Schwabedissen HE, Schwarz UI, Lemke CJ, Leake BF, Kim RB, and Tirona RG (2010) Human skeletal muscle drug transporters determine local exposure and toxicity of statins
-
Knauer MJ, Urquhart BL, Meyer zu Schwabedissen HE, Schwarz UI, Lemke CJ, Leake BF, Kim RB, and Tirona RG (2010) Human skeletal muscle drug transporters determine local exposure and toxicity of statins. Circ Res 106:297-306.
-
Circ Res
, vol.106
, pp. 297-306
-
-
Knauer, M.J.1
Urquhart, B.L.2
-
16
-
-
0038637144
-
Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane
-
DOI 10.1124/jpet.103.051300
-
Kobayashi D, Nozawa T, Imai K, Nezu J, Tsuji A, and Tamai I (2003) Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. J Pharmacol Exp Ther 306:703-708. (Pubitemid 36886171)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.306
, Issue.2
, pp. 703-708
-
-
Kobayashi, D.1
Nozawa, T.2
Imai, K.3
Nezu, J.-I.4
Tsuji, A.5
Tamai, I.6
-
17
-
-
25144494314
-
Human hepatobiliary transport of organic anions analyzed by quadruple-transfected cells
-
DOI 10.1124/mol.105.014605
-
Kopplow K, Letschert K, König J, Walter B, and Keppler D (2005) Human hepatobiliary transport of organic anions analyzed by quadruple- transfected cells. Mol Pharmacol 68:1031-1038. (Pubitemid 41345794)
-
(2005)
Molecular Pharmacology
, vol.68
, Issue.4
, pp. 1031-1038
-
-
Kopplow, K.1
Letschert, K.2
Konig, J.3
Walter, B.4
Keppler, D.5
-
18
-
-
0035125407
-
Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver
-
Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, and Hagenbuch B (2001) Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology 120:525-533. (Pubitemid 32147650)
-
(2001)
Gastroenterology
, vol.120
, Issue.2
, pp. 525-533
-
-
Kullak-Ublick, G.A.1
Ismair, M.G.2
Stieger, B.3
Landmann, L.4
Huber, R.5
Pizzagalli, F.6
Fattinger, K.7
Meier, P.J.8
Hagenbuch, B.9
-
19
-
-
65249143403
-
Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters
-
Leuthold S, Hagenbuch B, Mohebbi N, Wagner CA, Meier PJ, and Stieger B (2009) Mechanisms of pH-gradient driven transport mediated by organic anion polypeptide transporters. Am J Physiol Cell Physiol 296:C570-C582.
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Leuthold, S.1
Hagenbuch, B.2
Mohebbi, N.3
Wagner, C.A.4
Meier, P.J.5
Stieger, B.6
-
20
-
-
33644917724
-
Characterization of human OATP2B1 (SLCO2B1) gene promoter regulation
-
Maeda T, Hirayama M, Higashi R, Sato M, and Tamai I (2006) Characterization of human OATP2B1 (SLCO2B1) gene promoter regulation. Pharm Res 23:513-520.
-
(2006)
Pharm Res
, vol.23
, pp. 513-520
-
-
Maeda, T.1
Hirayama, M.2
Higashi, R.3
Sato, M.4
Tamai, I.5
-
21
-
-
66449098497
-
Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin
-
Niessen J, Jedlitschky G, Grube M, Bien S, Schwertz H, Ohtsuki S, Kawakami H, Kamiie J, Oswald S, and Starke K et al. (2009) Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin. Drug Metab Dispos 37:1129-1137.
-
(2009)
Drug Metab Dispos
, vol.37
, pp. 1129-1137
-
-
Niessen, J.1
Jedlitschky, G.2
Grube, M.3
Bien, S.4
Schwertz, H.5
Ohtsuki, S.6
Kawakami, H.7
Kamiie, J.8
Oswald, S.9
Starke, K.10
-
22
-
-
1642457252
-
Functional Characterization of pH-Sensitive Organic Anion Transporting Polypeptide OATP-B in Human
-
DOI 10.1124/jpet.103.060194
-
Nozawa T, Imai K, Nezu J, Tsuji A, and Tamai I (2004a) Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J Pharmacol Exp Ther 308:438-445. (Pubitemid 38134202)
-
(2004)
Journal of Pharmacology and Experimental Therapeutics
, vol.308
, Issue.2
, pp. 438-445
-
-
Nozawa, T.1
Imai, K.2
Nezu, J.-I.3
Tsuji, A.4
Tamai, I.5
-
23
-
-
1342302280
-
Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: Implications for understanding troglitazone hepatotoxicity
-
DOI 10.1124/dmd.32.3.291
-
Nozawa T, Sugiura S, Nakajima M, Goto A, Yokoi T, Nezu J, Tsuji A, and Tamai I (2004b) Involvement of organic anion transporting polypeptides in the transport of troglitazone sulfate: Implications for understanding troglitazone hepatotoxicity. Drug Metab Dispos 32:291-294. (Pubitemid 38263886)
-
(2004)
Drug Metabolism and Disposition
, vol.32
, Issue.3
, pp. 291-294
-
-
Nozawa, T.1
Sugiura, S.2
Nakajima, M.3
Goto, A.4
Yokoi, T.5
Nezu, J.-I.6
Tsuji, A.7
Tamai, I.8
-
24
-
-
53049109106
-
Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1
-
Oswald S, König J, Lütjohann D, Giessmann T, Kroemer HK, Rimmbach C, Rosskopf D, Fromm MF, and Siegmund W (2008) Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1. Pharmacogenet Genomics 18:559-568.
-
(2008)
Pharmacogenet Genomics
, vol.18
, pp. 559-568
-
-
Oswald, S.1
König, J.2
Lütjohann, D.3
Giessmann, T.4
Kroemer, H.K.5
Rimmbach, C.6
Rosskopf, D.7
Fromm, M.F.8
Siegmund, W.9
-
25
-
-
85047682066
-
NUBIScan, an in Silico approach for prediction of nuclear receptor response elements
-
DOI 10.1210/me.16.6.1269
-
Podvinec M, Kaufmann MR, Handschin C, and Meyer UA (2002) NUBIScan, an in silico approach for prediction of nuclear receptor response elements. Mol Endocrinol 16:1269-1279. (Pubitemid 34621075)
-
(2002)
Molecular Endocrinology
, vol.16
, Issue.6
, pp. 1269-1279
-
-
Podvinec, M.1
Kaufmann, M.R.2
Handschin, C.3
Meyer, U.A.4
-
26
-
-
67349246526
-
Transcriptional control of human organic anion transporting polypeptide 2B1 gene
-
Pomari E, Nardi A, Fiore C, Celeghin A, Colombo L, and Dalla Valle L (2009) Transcriptional control of human organic anion transporting polypeptide 2B1 gene. J Steroid Biochem Mol Biol 115:146-152.
-
(2009)
J Steroid Biochem Mol Biol
, vol.115
, pp. 146-152
-
-
Pomari, E.1
Nardi, A.2
Fiore, C.3
Celeghin, A.4
Colombo, L.5
Dalla Valle, L.6
-
27
-
-
17844385785
-
The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 and suppressed by bile acids
-
DOI 10.1124/mol.104.010223
-
Popowski K, Eloranta JJ, Saborowski M, Fried M, Meier PJ, and Kullak-Ublick GA (2005) The human organic anion transporter 2 gene is transactivated by hepatocyte nuclear factor-4 alpha and suppressed by bile acids. Mol Pharmacol 67:1629-1638. (Pubitemid 40594162)
-
(2005)
Molecular Pharmacology
, vol.67
, Issue.5
, pp. 1629-1638
-
-
Popowski, K.1
Eloranta, J.J.2
Saborowski, M.3
Fried, M.4
Meier, P.J.5
Kullak-Ublick, G.A.6
-
28
-
-
33645870991
-
The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha
-
Saborowski M, Kullak-Ublick GA, and Eloranta JJ (2006) The human organic cation transporter-1 gene is transactivated by hepatocyte nuclear factor-4alpha. J Pharmacol Exp Ther 317:778-785.
-
(2006)
J Pharmacol Exp Ther
, vol.317
, pp. 778-785
-
-
Saborowski, M.1
Kullak-Ublick, G.A.2
Eloranta, J.J.3
-
29
-
-
33746048844
-
Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells
-
DOI 10.1124/dmd.106.009530
-
Sai Y, Kaneko Y, Ito S, Mitsuoka K, Kato Y, Tamai I, Artursson P, and Tsuji A (2006) Predominant contribution of organic anion transporting polypeptide OATP-B (OATP2B1) to apical uptake of estrone-3-sulfate by human intestinal Caco-2 cells. Drug Metab Dispos 34:1423-1431. (Pubitemid 44079886)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.8
, pp. 1423-1431
-
-
Sai, Y.1
Kaneko, Y.2
Ito, S.3
Mitsuoka, K.4
Kato, Y.5
Tamai, I.6
Artursson, P.7
Tsuji, A.8
-
30
-
-
15344340313
-
Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B
-
DOI 10.1124/dmd.104.002337
-
Satoh H, Yamashita F, Tsujimoto M, Murakami H, Koyabu N, Ohtani H, and Sawada Y (2005) Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 33:518-523. (Pubitemid 40393194)
-
(2005)
Drug Metabolism and Disposition
, vol.33
, Issue.4
, pp. 518-523
-
-
Satoh, H.1
Yamashita, F.2
Tsujimoto, M.3
Murakami, H.4
Koyabu, N.5
Ohtani, H.6
Sawada, Y.7
-
31
-
-
84863193091
-
Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites
-
Shirasaka Y, Mori T, Shichiri M, Nakanishi T, and Tamai I (2012) Functional pleiotropy of organic anion transporting polypeptide OATP2B1 due to multiple binding sites. Drug Metab Pharmacokinet 27:360-364.
-
(2012)
Drug Metab Pharmacokinet
, vol.27
, pp. 360-364
-
-
Shirasaka, Y.1
Mori, T.2
Shichiri, M.3
Nakanishi, T.4
Tamai, I.5
-
32
-
-
77957337144
-
Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide
-
Shirasaka Y, Suzuki K, Nakanishi T, and Tamai I (2010) Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide. Pharm Res 27:2141-2149.
-
(2010)
Pharm Res
, vol.27
, pp. 2141-2149
-
-
Shirasaka, Y.1
Suzuki, K.2
Nakanishi, T.3
Tamai, I.4
-
33
-
-
79955740281
-
Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1
-
Shirasaka Y, Suzuki K, Shichiri M, Nakanishi T, and Tamai I (2011) Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1. Drug Metab Pharmacokinet 26:171-179.
-
(2011)
Drug Metab Pharmacokinet
, vol.26
, pp. 171-179
-
-
Shirasaka, Y.1
Suzuki, K.2
Shichiri, M.3
Nakanishi, T.4
Tamai, I.5
-
34
-
-
0034709561
-
Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family
-
DOI 10.1006/bbrc.2000.2922
-
Tamai I, Nezu J, Uchino H, Sai Y, Oku A, Shimane M, and Tsuji A (2000) Molecular identification and characterization of novel members of the human organic anion transporter (OATP) family. Biochem Biophys Res Commun 273:251-260. (Pubitemid 30426895)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.273
, Issue.1
, pp. 251-260
-
-
Tamai, I.1
Nezu, J.-I.2
Uchino, H.3
Sai, Y.4
Oku, A.5
Shimane, M.6
Tsuji, A.7
-
35
-
-
0034857677
-
Functional characterization of human organic anion transporting polypeptide b (OATP-B) in comparison with liver-specific OATP-C
-
DOI 10.1023/A:1013077609227
-
Tamai I, Nozawa T, Koshida M, Nezu J, Sai Y, and Tsuji A (2001) Functional characterization of human organic anion transporting polypeptide B (OATP-B) in comparison with liver-specific OATP-C. Pharm Res 18:1262-1269. (Pubitemid 32846318)
-
(2001)
Pharmaceutical Research
, vol.18
, Issue.9
, pp. 1262-1269
-
-
Tamai, I.1
Nozawa, T.2
Koshida, M.3
Nezu, J.-I.4
Sai, Y.5
Tsuji, A.6
-
36
-
-
0037216648
-
Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation
-
DOI 10.1124/jpet.102.043026
-
Tirona RG, Leake BF, Wolkoff AW, and Kim RB (2003a) Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampinmediated pregnane X receptor activation. J Pharmacol Exp Ther 304:223-228. (Pubitemid 36008932)
-
(2003)
Journal of Pharmacology and Experimental Therapeutics
, vol.304
, Issue.1
, pp. 223-228
-
-
Tirona, R.G.1
Leake, B.F.2
Wolkoff, A.W.3
Kim, R.B.4
-
37
-
-
0037327003
-
The orphan nuclear receptor HNF4 determines PXR- and CAR-mediated xenobiotic induction of CYP3A4
-
DOI 10.1038/nm815
-
Tirona RG, Lee W, Leake BF, Lan LB, Cline CB, Lamba V, Parviz F, Duncan SA, Inoue Y, and Gonzalez FJ et al. (2003b) The orphan nuclear receptor HNF4alpha determines PXR-and CAR-mediated xenobiotic induction of CYP3A4. Nat Med 9: 220-224. (Pubitemid 36227725)
-
(2003)
Nature Medicine
, vol.9
, Issue.2
, pp. 220-224
-
-
Tirona, R.G.1
Lee, W.2
Leake, B.F.3
Lan, L.-B.4
Brimer Cline, C.5
Lamba, V.6
Parviz, F.7
Duncan, S.A.8
Inoue, Y.9
Gonzalez, F.J.10
Schuetz, E.G.11
Kim, R.B.12
-
38
-
-
34547212999
-
Bosentan is a substrate of human OATP1B1 and OATP1B3: Inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil
-
DOI 10.1124/dmd.106.013615
-
Treiber A, Schneiter R, Häusler S, and Stieger B (2007) Bosentan is a substrate of human OATP1B1 and OATP1B3: Inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil. Drug Metab Dispos 35:1400-1407. (Pubitemid 47121782)
-
(2007)
Drug Metabolism and Disposition
, vol.35
, Issue.8
, pp. 1400-1407
-
-
Treiber, A.1
Schneiter, R.2
Hausler, S.3
Stieger, B.4
-
39
-
-
0037305411
-
Characterization and identification of steroid sulfate transporters of human placenta
-
Ugele B, St-Pierre MV, Pihusch M, Bahn A, and Hantschmann P (2003) Characterization and identification of steroid sulfate transporters of human placenta. Am J Physiol Endocrinol Metab 284:E390-E398. (Pubitemid 36120113)
-
(2003)
American Journal of Physiology - Endocrinology and Metabolism
, vol.284
, Issue.2
-
-
Ugele, B.1
St-Pierre, M.V.2
Pihusch, M.3
Bahn, A.4
Hantschmann, P.5
-
40
-
-
76749135846
-
The human proton-coupled folate transporter (hPCFT): Modulation of intestinal expression and function by drugs
-
Urquhart BL, Gregor JC, Chande N, Knauer MJ, Tirona RG, and Kim RB (2010) The human proton-coupled folate transporter (hPCFT): Modulation of intestinal expression and function by drugs. Am J Physiol Gastrointest Liver Physiol 298: G248-G254.
-
(2010)
Am J Physiol Gastrointest Liver Physiol
, vol.298
-
-
Urquhart, B.L.1
Gregor, J.C.2
Chande, N.3
Knauer, M.J.4
Tirona, R.G.5
Kim, R.B.6
-
41
-
-
79961089466
-
PH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1
-
Varma MV, Rotter CJ, Chupka J, Whalen KM, Duignan DB, Feng B, Litchfield J, Goosen TC, and El-Kattan AF (2011) pH-sensitive interaction of HMG-CoA reductase inhibitors (statins) with organic anion transporting polypeptide 2B1. Mol Pharm 8:1303-1313.
-
(2011)
Mol Pharm
, vol.8
, pp. 1303-1313
-
-
Varma, M.V.1
Rotter, C.J.2
Chupka, J.3
Whalen, K.M.4
Duignan, D.B.5
Feng, B.6
Litchfield, J.7
Goosen, T.C.8
El-Kattan, A.F.9
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