HNF4α-role in drug metabolism and potential drug target?

Current Opinion in Pharmacology

Volumn 10, Issue 6, 2010, Pages 698-705

  Hwang Verslues, Wendy W ^a   Sladek, Frances M ^b  

^a GENOMICS RESEARCH CENTER   (Taiwan)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450; GLUCURONOSYLTRANSFERASE; GLUTATHIONE TRANSFERASE; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; PREGNANE X RECEPTOR; STAT5B PROTEIN; STEROID RECEPTOR COACTIVATOR 1; SULFOTRANSFERASE; VITAMIN D RECEPTOR; XENOBIOTIC AGENT;

BINDING SITE; CLINICAL TRIAL; DIET; DOWN REGULATION; DRUG METABOLISM; DRUG TARGETING; ENHANCER REGION; ENVIRONMENTAL FACTOR; GENE ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE MUTATION; GLUCOSE METABOLISM; HEMOPHILIA; HUMAN; LIPID TRANSPORT; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW; SEX DIFFERENCE; SUPPORT VECTOR MACHINE; TRANSCRIPTION REGULATION; UPREGULATION;

CYTOCHROME P-450 ENZYME SYSTEM; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 4; HUMANS; LIVER; MALE; METABOLIC DETOXICATION, DRUG; MOLECULAR TARGETED THERAPY; PHARMACEUTICAL PREPARATIONS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REGULATORY ELEMENTS, TRANSCRIPTIONAL; SEX CHARACTERISTICS; TRANSCRIPTION FACTORS;

EID: 78149496291     PISSN: 14714892     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coph.2010.08.010     Document Type: Review

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