메뉴 건너뛰기




Volumn 130, Issue 6, 2006, Pages 1793-1806

Drug and Bile Acid Transporters in Rosuvastatin Hepatic Uptake: Function, Expression, and Pharmacogenetics

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CARRIER PROTEINS AND BINDING PROTEINS; MESSENGER RNA; ORGANIC ANION TRANSPORTER 2; RNA; ROSUVASTATIN; SODIUM DEPENDENT TAUROCHOLATE COTRANSPORTING POLYPEPTIDE; UNCLASSIFIED DRUG;

EID: 33646536542     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2006.02.034     Document Type: Article
Times cited : (549)

References (41)
  • 1
    • 2442674610 scopus 로고    scopus 로고
    • American Heart Association, American Heart Association, Dallas, TX
    • American Heart Association. Heart disease and stroke statistics-2005 Update. 1-60 (2005), American Heart Association, Dallas, TX
    • (2005) Heart disease and stroke statistics-2005 Update. 1-60
  • 2
    • 0031761005 scopus 로고    scopus 로고
    • The response-to-retention hypothesis of atherogenesis reinforced
    • Williams K.J., and Tabas I. The response-to-retention hypothesis of atherogenesis reinforced. Curr Opin Lipidol 9 (1998) 471-474
    • (1998) Curr Opin Lipidol , vol.9 , pp. 471-474
    • Williams, K.J.1    Tabas, I.2
  • 3
    • 0029650740 scopus 로고
    • Cholesterol reduction in cardiovascular disease. Clinical benefits and possible mechanisms
    • Levine G.N., Keaney Jr. J.F., and Vita J.A. Cholesterol reduction in cardiovascular disease. Clinical benefits and possible mechanisms. N Engl J Med 332 (1995) 512-521
    • (1995) N Engl J Med , vol.332 , pp. 512-521
    • Levine, G.N.1    Keaney Jr., J.F.2    Vita, J.A.3
  • 4
    • 0033984125 scopus 로고    scopus 로고
    • The evolving role of statins in the management of atherosclerosis
    • Vaughan C.J., Gotto Jr. A.M., and Basson C.T. The evolving role of statins in the management of atherosclerosis. J Am Coll Cardiol 35 (2000) 1-10
    • (2000) J Am Coll Cardiol , vol.35 , pp. 1-10
    • Vaughan, C.J.1    Gotto Jr., A.M.2    Basson, C.T.3
  • 5
    • 18744384338 scopus 로고    scopus 로고
    • Efficacy and safety of rosuvastatin in treatment of dyslipidemia
    • McKenney J.M. Efficacy and safety of rosuvastatin in treatment of dyslipidemia. Am J Health Syst Pharm 62 (2005) 1033-1047
    • (2005) Am J Health Syst Pharm , vol.62 , pp. 1033-1047
    • McKenney, J.M.1
  • 6
    • 0242509092 scopus 로고    scopus 로고
    • Absolute oral bioavailability of rosuvastatin in healthy white adult male volunteers
    • Martin P.D., Warwick M.J., Dane A.L., Brindley C., and Short T. Absolute oral bioavailability of rosuvastatin in healthy white adult male volunteers. Clin Ther 25 (2003) 2553-2563
    • (2003) Clin Ther , vol.25 , pp. 2553-2563
    • Martin, P.D.1    Warwick, M.J.2    Dane, A.L.3    Brindley, C.4    Short, T.5
  • 8
    • 0033601257 scopus 로고    scopus 로고
    • A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters
    • Hsiang B., Zhu Y., Wang Z., Wu Y., Sasseville V., Yang W.P., and Kirchgessner T.G. A novel human hepatic organic anion transporting polypeptide (OATP2). Identification of a liver-specific human organic anion transporting polypeptide and identification of rat and human hydroxymethylglutaryl-CoA reductase inhibitor transporters. J Biol Chem 274 (1999) 37161-37168
    • (1999) J Biol Chem , vol.274 , pp. 37161-37168
    • Hsiang, B.1    Zhu, Y.2    Wang, Z.3    Wu, Y.4    Sasseville, V.5    Yang, W.P.6    Kirchgessner, T.G.7
  • 9
    • 0141560665 scopus 로고    scopus 로고
    • Comparative pharmacology of rosuvastatin
    • McTaggart F. Comparative pharmacology of rosuvastatin. Atheroscler Suppl 4 (2003) 9-14
    • (2003) Atheroscler Suppl , vol.4 , pp. 9-14
    • McTaggart, F.1
  • 10
    • 0242469240 scopus 로고    scopus 로고
    • Organic anion-transporting polypeptide (OATP) transporter family and drug disposition
    • Kim R.B. Organic anion-transporting polypeptide (OATP) transporter family and drug disposition. Eur J Clin Invest 33 Suppl 2 (2003) 1-5
    • (2003) Eur J Clin Invest , vol.33 , Issue.SUPPL. 2 , pp. 1-5
    • Kim, R.B.1
  • 13
    • 0027327029 scopus 로고
    • Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients
    • Regazzi M.B., Iacona I., Campana C., Raddato V., Lesi C., Perani G., Gavazzi A., and Vigano M. Altered disposition of pravastatin following concomitant drug therapy with cyclosporin A in transplant recipients. Transplant Proc 25 (1993) 2732-2734
    • (1993) Transplant Proc , vol.25 , pp. 2732-2734
    • Regazzi, M.B.1    Iacona, I.2    Campana, C.3    Raddato, V.4    Lesi, C.5    Perani, G.6    Gavazzi, A.7    Vigano, M.8
  • 14
    • 0037310871 scopus 로고    scopus 로고
    • Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A
    • Shitara Y., Itoh T., Sato H., Li A.P., and Sugiyama Y. Inhibition of transporter-mediated hepatic uptake as a mechanism for drug-drug interaction between cerivastatin and cyclosporin A. J Pharmacol Exp Ther 304 (2003) 610-616
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 610-616
    • Shitara, Y.1    Itoh, T.2    Sato, H.3    Li, A.P.4    Sugiyama, Y.5
  • 15
    • 0037216648 scopus 로고    scopus 로고
    • Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation
    • Tirona R.G., Leake B.F., Wolkoff A.W., and Kim R.B. Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation. J Pharmacol Exp Ther 304 (2003) 223-228
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 223-228
    • Tirona, R.G.1    Leake, B.F.2    Wolkoff, A.W.3    Kim, R.B.4
  • 16
    • 0035929574 scopus 로고    scopus 로고
    • Polymorphisms in OATP-C. identification of multiple allelic variants associated with altered transport activity among European- and African-Americans
    • Tirona R.G., Leake B.F., Merino G., and Kim R.B. Polymorphisms in OATP-C. identification of multiple allelic variants associated with altered transport activity among European- and African-Americans. J Biol Chem 276 (2001) 35669-35675
    • (2001) J Biol Chem , vol.276 , pp. 35669-35675
    • Tirona, R.G.1    Leake, B.F.2    Merino, G.3    Kim, R.B.4
  • 17
    • 1342304081 scopus 로고    scopus 로고
    • Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition
    • Ho R.H., Leake B.F., Roberts R.L., Lee W., and Kim R.B. Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition. J Biol Chem 279 (2004) 7213-7222
    • (2004) J Biol Chem , vol.279 , pp. 7213-7222
    • Ho, R.H.1    Leake, B.F.2    Roberts, R.L.3    Lee, W.4    Kim, R.B.5
  • 18
    • 0032732615 scopus 로고    scopus 로고
    • Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity
    • Kim R.B., Leake B., Cvetkovic M., Roden M.M., Nadeau J., Walubo A., and Wilkinson G.R. Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. J Pharmacol Exp Ther 291 (1999) 1204-1209
    • (1999) J Pharmacol Exp Ther , vol.291 , pp. 1204-1209
    • Kim, R.B.1    Leake, B.2    Cvetkovic, M.3    Roden, M.M.4    Nadeau, J.5    Walubo, A.6    Wilkinson, G.R.7
  • 19
    • 0342912311 scopus 로고
    • Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers
    • Singer I.I., Kawka D.W., Kazazis D.M., Alberts A.W., Chen J.S., Huff J.W., and Ness G.C. Hydroxymethylglutaryl-coenzyme A reductase-containing hepatocytes are distributed periportally in normal and mevinolin-treated rat livers. Proc Natl Acad Sci U S A 81 (1984) 5556-5560
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 5556-5560
    • Singer, I.I.1    Kawka, D.W.2    Kazazis, D.M.3    Alberts, A.W.4    Chen, J.S.5    Huff, J.W.6    Ness, G.C.7
  • 20
    • 0032943219 scopus 로고    scopus 로고
    • Lack of zonal uptake of estrone sulfate in enriched periportal and perivenous isolated rat hepatocytes
    • Tan E., Tirona R.G., and Pang K.S. Lack of zonal uptake of estrone sulfate in enriched periportal and perivenous isolated rat hepatocytes. Drug Metab Dispos 27 (1999) 336-341
    • (1999) Drug Metab Dispos , vol.27 , pp. 336-341
    • Tan, E.1    Tirona, R.G.2    Pang, K.S.3
  • 24
    • 0032422456 scopus 로고    scopus 로고
    • Contribution of sodium taurocholate co-transporting polypeptide to the uptake of its possible substrates into rat hepatocytes
    • Kouzuki H., Suzuki H., Ito K., Ohashi R., and Sugiyama Y. Contribution of sodium taurocholate co-transporting polypeptide to the uptake of its possible substrates into rat hepatocytes. J Pharmacol Exp Ther 286 (1998) 1043-1050
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1043-1050
    • Kouzuki, H.1    Suzuki, H.2    Ito, K.3    Ohashi, R.4    Sugiyama, Y.5
  • 25
    • 0020617090 scopus 로고
    • Direct determination of the driving forces for taurocholate uptake into rat liver plasma membrane vesicles
    • Duffy M.C., Blitzer B.L., and Boyer J.L. Direct determination of the driving forces for taurocholate uptake into rat liver plasma membrane vesicles. J Clin Invest 72 (1983) 1470-1481
    • (1983) J Clin Invest , vol.72 , pp. 1470-1481
    • Duffy, M.C.1    Blitzer, B.L.2    Boyer, J.L.3
  • 26
    • 0030724010 scopus 로고    scopus 로고
    • Organic anion transporting polypeptide mediates organic anion/HCO3- exchange
    • Satlin L.M., Amin V., and Wolkoff A.W. Organic anion transporting polypeptide mediates organic anion/HCO3- exchange. J Biol Chem 272 (1997) 26340-26345
    • (1997) J Biol Chem , vol.272 , pp. 26340-26345
    • Satlin, L.M.1    Amin, V.2    Wolkoff, A.W.3
  • 27
    • 10044240704 scopus 로고    scopus 로고
    • Comparative effects of lipid-lowering therapies
    • Davidson M.H., and Toth P.P. Comparative effects of lipid-lowering therapies. Prog Cardiovasc Dis 47 (2004) 73-104
    • (2004) Prog Cardiovasc Dis , vol.47 , pp. 73-104
    • Davidson, M.H.1    Toth, P.P.2
  • 28
    • 2042469487 scopus 로고    scopus 로고
    • Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics
    • Mwinyi J., Johne A., Bauer S., Roots I., and Gerloff T. Evidence for inverse effects of OATP-C (SLC21A6) 5 and 1b haplotypes on pravastatin kinetics. Clin Pharmacol Ther 75 (2004) 415-421
    • (2004) Clin Pharmacol Ther , vol.75 , pp. 415-421
    • Mwinyi, J.1    Johne, A.2    Bauer, S.3    Roots, I.4    Gerloff, T.5
  • 31
    • 0036073404 scopus 로고    scopus 로고
    • Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9). allele frequencies in the Japanese population and functional analysis
    • Nozawa T., Nakajima M., Tamai I., Noda K., Nezu J., Sai Y., Tsuji A., and Yokoi T. Genetic polymorphisms of human organic anion transporters OATP-C (SLC21A6) and OATP-B (SLC21A9). allele frequencies in the Japanese population and functional analysis. J Pharmacol Exp Ther 302 (2002) 804-813
    • (2002) J Pharmacol Exp Ther , vol.302 , pp. 804-813
    • Nozawa, T.1    Nakajima, M.2    Tamai, I.3    Noda, K.4    Nezu, J.5    Sai, Y.6    Tsuji, A.7    Yokoi, T.8
  • 34
    • 0037379362 scopus 로고    scopus 로고
    • Bile salt transporters. molecular characterization, function, and regulation
    • Trauner M., and Boyer J.L. Bile salt transporters. molecular characterization, function, and regulation. Physiol Rev 83 (2003) 633-671
    • (2003) Physiol Rev , vol.83 , pp. 633-671
    • Trauner, M.1    Boyer, J.L.2
  • 35
    • 1242317691 scopus 로고    scopus 로고
    • The sodium bile salt cotransport family SLC10
    • Hagenbuch B., and Dawson P. The sodium bile salt cotransport family SLC10. Pflugers Arch 447 (2004) 566-570
    • (2004) Pflugers Arch , vol.447 , pp. 566-570
    • Hagenbuch, B.1    Dawson, P.2
  • 37
    • 24944537019 scopus 로고    scopus 로고
    • Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes
    • Jigorel E., Le Vee M., Boursier-Neyret C., Bertrand M., and Fardel O. Functional expression of sinusoidal drug transporters in primary human and rat hepatocytes. Drug Metab Dispos 33 (2005) 1418-1422
    • (2005) Drug Metab Dispos , vol.33 , pp. 1418-1422
    • Jigorel, E.1    Le Vee, M.2    Boursier-Neyret, C.3    Bertrand, M.4    Fardel, O.5
  • 38
    • 85024471761 scopus 로고    scopus 로고
    • Function of uptake transporters for taurocholate and estradiol 17β-D-glucuronide in cryopreserved human hepatocytes
    • Shitara Y., Li A.P., Kato Y., Lu C., Ito K., Itoh T., and Sugiyama Y. Function of uptake transporters for taurocholate and estradiol 17β-D-glucuronide in cryopreserved human hepatocytes. Drug Metab Pharmacokinet 18 (2003) 33-41
    • (2003) Drug Metab Pharmacokinet , vol.18 , pp. 33-41
    • Shitara, Y.1    Li, A.P.2    Kato, Y.3    Lu, C.4    Ito, K.5    Itoh, T.6    Sugiyama, Y.7
  • 41
    • 15544378130 scopus 로고    scopus 로고
    • Pleiotropic effects of statins. moving beyond cholesterol control
    • Garcia P.J. Pleiotropic effects of statins. moving beyond cholesterol control. Curr Atheroscler Rep 7 (2005) 34-39
    • (2005) Curr Atheroscler Rep , vol.7 , pp. 34-39
    • Garcia, P.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.