-
1
-
-
3142589026
-
The nuclear receptor superfamily
-
McEwan,I. (ed.), Portland Press Ltd, London
-
Laudet,V., Thompson,B., Pratt,W., Claessens,F., Kraus,L., Baniahmad,A., Edwards,D., Trifiro,M., Chrousos,G., Gustafsson,J. et al. (2004) The nuclear receptor superfamily. In: McEwan,I. (ed.), Essays in Biochemistry, Vol. 40. Portland Press Ltd, London.
-
(2004)
Essays in Biochemistry
, vol.40
-
-
Laudet, V.1
Thompson, B.2
Pratt, W.3
Claessens, F.4
Kraus, L.5
Baniahmad, A.6
Edwards, D.7
Trifiro, M.8
Chrousos, G.9
Gustafsson, J.10
-
2
-
-
50449111314
-
Nuclear receptor drug discovery
-
Chen,T. (2008) Nuclear receptor drug discovery. Curr. Opin. Chem. Biol., 12, 418-426.
-
(2008)
Curr. Opin. Chem. Biol.
, vol.12
, pp. 418-426
-
-
Chen, T.1
-
3
-
-
33751547539
-
How many drug targets are there?
-
DOI 10.1038/nrd2199, PII NRD2199
-
Overington,J.P., Al-Lazikani,B. and Hopkins,A.L. (2006) How many drug targets are there? Nat. Rev. Drug Discov., 5, 993-996. (Pubitemid 44835126)
-
(2006)
Nature Reviews Drug Discovery
, vol.5
, Issue.12
, pp. 993-996
-
-
Overington, J.P.1
Al-Lazikani, B.2
Hopkins, A.L.3
-
5
-
-
0024337858
-
Determinants of target gene specificity for steroid/thyroid hormone receptors
-
DOI 10.1016/0092-8674(89)90051-2
-
Umesono,K. and Evans,R.M. (1989) Determinants of target gene specificity for steroid/thyroid hormone receptors. Cell, 57, 1139-1146. (Pubitemid 19169810)
-
(1989)
Cell
, vol.57
, Issue.7
, pp. 1139-1146
-
-
Umesono, K.1
Evans, R.M.2
-
6
-
-
0023913120
-
The steroid and thyroid hormone receptor superfamily
-
Evans,R.M. (1988) The steroid and thyroid hormone receptor superfamily. Science, 240, 889-895.
-
(1988)
Science
, vol.240
, pp. 889-895
-
-
Evans, R.M.1
-
7
-
-
79951682260
-
Evolution of the repertoire of nuclear receptor binding sites in genomes
-
Cotnoir-White,D., Laperriere,D. and Mader,S. (2011) Evolution of the repertoire of nuclear receptor binding sites in genomes. Mol. Cell Endocrinol., 334, 76-82.
-
(2011)
Mol. Cell Endocrinol.
, vol.334
, pp. 76-82
-
-
Cotnoir-White, D.1
Laperriere, D.2
Mader, S.3
-
8
-
-
0025812291
-
3 receptors
-
Umesono,K., Murakami,K.K., Thompson,C.C. and Evans,R.M. (1991) Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell, 65, 1255-1266. (Pubitemid 121001338)
-
(1991)
Cell
, vol.65
, Issue.7
, pp. 1255-1266
-
-
Umesono, K.1
Murakami, K.K.2
Thompson, C.C.3
Evans, R.M.4
-
9
-
-
79951671138
-
What are nuclear receptor ligands?
-
Sladek,F.M. (2011) What are nuclear receptor ligands? Mol. Cell Endocrinol., 334, 3-13.
-
(2011)
Mol. Cell Endocrinol.
, vol.334
, pp. 3-13
-
-
Sladek, F.M.1
-
10
-
-
33747154772
-
Anatomical Profiling of Nuclear Receptor Expression Reveals a Hierarchical Transcriptional Network
-
DOI 10.1016/j.cell.2006.06.049, PII S0092867406009779
-
Bookout,A.L., Jeong,Y., Downes,M., Yu,R.T., Evans,R.M. and Mangelsdorf,D.J. (2006) Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional network. Cell, 126, 789-799. (Pubitemid 44233630)
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 789-799
-
-
Bookout, A.L.1
Jeong, Y.2
Downes, M.3
Yu, R.T.4
Evans, R.M.5
Mangelsdorf, D.J.6
-
11
-
-
66049149024
-
Identification of an endogenous ligand bound to a native orphan nuclear receptor
-
Yuan,X., Ta,T.C., Lin,M., Evans,J.R., Dong,Y., Bolotin,E., Sherman,M.A., Forman,B.M. and Sladek,F.M. (2009) Identification of an endogenous ligand bound to a native orphan nuclear receptor. PLoS One, 4, e5609.
-
(2009)
PLoS One
, vol.4
-
-
Yuan, X.1
Ta, T.C.2
Lin, M.3
Evans, J.R.4
Dong, Y.5
Bolotin, E.6
Sherman, M.A.7
Forman, B.M.8
Sladek, F.M.9
-
12
-
-
78149496291
-
HNF4alpha-role in drug metabolism and potential drug target?
-
Hwang-Verslues,W.W. and Sladek,F.M. (2010) HNF4alpha-role in drug metabolism and potential drug target? Curr. Opin. Pharmacol., 10, 698-705.
-
(2010)
Curr. Opin. Pharmacol.
, vol.10
, pp. 698-705
-
-
Hwang-Verslues, W.W.1
Sladek, F.M.2
-
13
-
-
75449100306
-
Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays
-
Bolotin,E., Liao,H., Ta,T.C., Yang,C., Hwang-Verslues,W., Evans,J.R., Jiang,T. and Sladek,F.M. (2010) Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays. Hepatology, 51, 642-653.
-
(2010)
Hepatology
, vol.51
, pp. 642-653
-
-
Bolotin, E.1
Liao, H.2
Ta, T.C.3
Yang, C.4
Hwang-Verslues, W.5
Evans, J.R.6
Jiang, T.7
Sladek, F.M.8
-
14
-
-
75449103520
-
Making the liver what it is: The many targets of the transcriptional regulator HNF4alpha
-
Kaestner,K.H. (2010) Making the liver what it is: the many targets of the transcriptional regulator HNF4alpha. Hepatology, 51, 376-377.
-
(2010)
Hepatology
, vol.51
, pp. 376-377
-
-
Kaestner, K.H.1
-
15
-
-
10744227070
-
Control of Pancreas and Liver Gene Expression by HNF Transcription Factors
-
DOI 10.1126/science.1089769
-
Odom,D.T., Zizlsperger,N., Gordon,D.B., Bell,G.W., Rinaldi,N.J., Murray,H.L., Volkert,T.L., Schreiber,J., Rolfe,P.A., Gifford,D.K. et al. (2004) Control of pancreas and liver gene expression by HNF transcription factors. Science, 303, 1378-1381. (Pubitemid 38269432)
-
(2004)
Science
, vol.303
, Issue.5662
, pp. 1378-1381
-
-
Odom, D.T.1
Zizlsperger, H.2
Gordon, D.B.3
Bell, G.W.4
Rinaldi, N.J.5
Murray, H.L.6
Volkert, T.L.7
Schreiber, J.8
Rolfe, P.A.9
Gifford, D.K.10
Fraenkel, E.11
Bell, G.I.12
Young, R.A.13
-
16
-
-
82355176322
-
HNF4A (Homo sapiens)
-
17 February 2012, date last accessed
-
Bolotin,E., Schnabl,J. and Sladek,F. (2010) HNF4A (Homo sapiens). Transcription Factor Encyclopedia, http://www.cisreg.ca/tfe (17 February 2012, date last accessed).
-
(2010)
Transcription Factor Encyclopedia
-
-
Bolotin, E.1
Schnabl, J.2
Sladek, F.3
-
17
-
-
0002772438
-
Hepatocyte nuclear factor 4a
-
Burris,T.P. and McCabe,E. 75 (eds), Academic Press, London
-
Sladek,F.M. and Seidel,S. (2001) Hepatocyte nuclear factor 4a. In: Burris,T.P. and McCabe,E. 75 (eds), Nuclear Receptors and Genetic Disease. Academic Press, London.
-
(2001)
Nuclear Receptors and Genetic Disease
-
-
Sladek, F.M.1
Seidel, S.2
-
18
-
-
0029562554
-
The RXR heterodimers and orphan receptors
-
DOI 10.1016/0092-8674(95)90200-7
-
Mangelsdorf,D.J. and Evans,R.M. (1995) The RXR heterodimers and orphan receptors. Cell, 83, 841-850. (Pubitemid 26006526)
-
(1995)
Cell
, vol.83
, Issue.6
, pp. 841-850
-
-
Mangelsdorf, D.J.1
Evans, R.M.2
-
19
-
-
0025938132
-
A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR
-
Mangelsdorf,D.J., Umesono,K., Kliewer,S.A., Borgmeyer,U., Ong,E.S. and Evans,R.M. (1991) A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR. Cell, 66, 555-561. (Pubitemid 121001391)
-
(1991)
Cell
, vol.66
, Issue.3
, pp. 555-561
-
-
Mangelsdorf, D.J.1
Umesono, K.2
Kliewer, S.A.3
Borgmeyer, U.4
Ong, E.S.5
Evans, R.M.6
-
20
-
-
2942621879
-
In vivo activation of PPAR target genes by RXR homodimers
-
IJpenberg,A., Tan,N.S., Gelman,L., Kersten,S., Seydoux,J., Xu,J., Metzger,D., Canaple,L., Chambon,P., Wahli,W. et al. (2004) In vivo activation of PPAR target genes by RXR homodimers. EMBO J., 23, 2083-2091.
-
(2004)
EMBO J.
, vol.23
, pp. 2083-2091
-
-
IJpenberg, A.1
Tan, N.S.2
Gelman, L.3
Kersten, S.4
Seydoux, J.5
Xu, J.6
Metzger, D.7
Canaple, L.8
Chambon, P.9
Wahli, W.10
-
21
-
-
0026544431
-
Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling
-
Kliewer,S.A., Umesono,K., Heyman,R.A., Mangelsdorf,D.J., Dyck,J.A. and Evans,R.M. (1992) Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling. Proc. Natl Acad. Sci. USA, 89, 1448-1452.
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 1448-1452
-
-
Kliewer, S.A.1
Umesono, K.2
Heyman, R.A.3
Mangelsdorf, D.J.4
Dyck, J.A.5
Evans, R.M.6
-
22
-
-
0026705751
-
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors
-
Kliewer,S.A., Umesono,K., Noonan,D.J., Heyman,R.A. and Evans,R.M. (1992) Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature, 358, 771-774.
-
(1992)
Nature
, vol.358
, pp. 771-774
-
-
Kliewer, S.A.1
Umesono, K.2
Noonan, D.J.3
Heyman, R.A.4
Evans, R.M.5
-
23
-
-
0026592518
-
Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling
-
Kliewer,S.A., Umesono,K., Mangelsdorf,D.J. and Evans,R.M. (1992) Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling. Nature, 355, 446-449.
-
(1992)
Nature
, vol.355
, pp. 446-449
-
-
Kliewer, S.A.1
Umesono, K.2
Mangelsdorf, D.J.3
Evans, R.M.4
-
24
-
-
0026738479
-
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors
-
Cooney,A.J., Tsai,S.Y., O'Malley,B.W. and Tsai,M.J. (1992) Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol. Cell. Biol., 12, 4153-4163.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 4153-4163
-
-
Cooney, A.J.1
Tsai, S.Y.2
O'Malley, B.W.3
Tsai, M.J.4
-
25
-
-
8244237054
-
Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): Coming of age
-
DOI 10.1210/er.18.2.229
-
Tsai,S.Y. and Tsai,M.J. (1997) Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr. Rev., 18, 229-240. (Pubitemid 27171521)
-
(1997)
Endocrine Reviews
, vol.18
, Issue.2
, pp. 229-240
-
-
Tsai, S.Y.1
Tsai, M.-J.2
-
26
-
-
54749139305
-
Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor
-
Kruse,S.W., Suino-Powell,K., Zhou,X.E., Kretschman,J.E., Reynolds,R., Vonrhein,C., Xu,Y., Wang,L., Tsai,S.Y., Tsai,M.J. et al. (2008) Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol., 6, e227.
-
(2008)
PLoS Biol.
, vol.6
-
-
Kruse, S.W.1
Suino-Powell, K.2
Zhou, X.E.3
Kretschman, J.E.4
Reynolds, R.5
Vonrhein, C.6
Xu, Y.7
Wang, L.8
Tsai, S.Y.9
Tsai, M.J.10
-
27
-
-
0029113123
-
Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors
-
Jiang,G., Nepomuceno,L., Hopkins,K. and Sladek,F.M. (1995) Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors. Mol. Cell. Biol., 15, 5131-5143.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 5131-5143
-
-
Jiang, G.1
Nepomuceno, L.2
Hopkins, K.3
Sladek, F.M.4
-
28
-
-
0032524459
-
Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements
-
DOI 10.1093/nar/26.10.2491
-
Nakshatri,H. and Bhat-Nakshatri,P. (1998) Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements. Nucleic Acids Res., 26, 2491-2499. (Pubitemid 28297354)
-
(1998)
Nucleic Acids Research
, vol.26
, Issue.10
, pp. 2491-2499
-
-
Nakshatri, H.1
Bhat-Nakshatri, P.2
-
29
-
-
0028096213
-
The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers
-
Nakshatri,H. and Chambon,P. (1994) The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers. J. Biol. Chem., 269, 890-902. (Pubitemid 24032461)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.2
, pp. 890-902
-
-
Nakshatri, H.1
Chambon, P.2
-
30
-
-
0026589377
-
Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells
-
Mietus-Snyder,M., Sladek,F.M., Ginsburg,G.S., Kuo,C.F., Ladias,J.A., Darnell,J.E. Jr and Karathanasis,S.K. (1992) Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. Mol. Cell. Biol., 12, 1708-1718.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 1708-1718
-
-
Mietus-Snyder, M.1
Sladek, F.M.2
Ginsburg, G.S.3
Kuo, C.F.4
Ladias, J.A.5
Darnell Jr., J.E.6
Karathanasis, S.K.7
-
31
-
-
0032504251
-
Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element
-
DOI 10.1074/jbc.273.28.17810
-
Kardassis,D., Sacharidou,E. and Zannis,V.I. (1998) Transactivation of the human apolipoprotein CII promoter by orphan and ligand-dependent nuclear receptors. The regulatory element CIIC is a thyroid hormone response element. J. Biol. Chem., 273, 17810-17816. (Pubitemid 28355125)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.28
, pp. 17810-17816
-
-
Kardassis, D.1
Sacharidou, E.2
Zannis, V.I.3
-
32
-
-
0031751631
-
Transcriptional activation of the cholesterol 7alpha-hydroxylase gene (CYP7A) by nuclear hormone receptors
-
Crestani,M., Sadeghpour,A., Stroup,D., Galli,G. and Chiang,J.Y. (1998) Transcriptional activation of the cholesterol 7alpha-hydroxylase gene (CYP7A) by nuclear hormone receptors. J. Lipid Res., 39, 2192-2200. (Pubitemid 28523125)
-
(1998)
Journal of Lipid Research
, vol.39
, Issue.11
, pp. 2192-2200
-
-
Crestani, M.1
Sadeghpour, A.2
Stroup, D.3
Galli, G.4
Chiang, J.Y.L.5
-
33
-
-
73549121316
-
Genome-wide mechanisms of nuclear receptor action
-
Biddie,S.C., John,S. and Hager,G.L. (2010) Genome-wide mechanisms of nuclear receptor action. Trends Endocrinol. Metab., 21, 3-9.
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 3-9
-
-
Biddie, S.C.1
John, S.2
Hager, G.L.3
-
34
-
-
70349312354
-
ChIP-seq: Advantages and challenges of a maturing technology
-
Park,P.J. (2009) ChIP-seq: advantages and challenges of a maturing technology. Nat. Rev. Genet., 10, 669-680.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 669-680
-
-
Park, P.J.1
-
35
-
-
59949083631
-
Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors
-
Berger,M.F. and Bulyk,M.L. (2009) Universal protein-binding microarrays for the comprehensive characterization of the DNA-binding specificities of transcription factors. Nat. Protoc., 4, 393-411.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 393-411
-
-
Berger, M.F.1
Bulyk, M.L.2
-
36
-
-
0025008168
-
Sequence logos: A new way to display consensus sequences
-
Schneider,T.D. and Stephens,R.M. (1990) Sequence logos: a new way to display consensus sequences. Nucleic Acids Res., 18, 6097-6100.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 6097-6100
-
-
Schneider, T.D.1
Stephens, R.M.2
-
37
-
-
2142738304
-
WebLogo: A sequence logo generator
-
DOI 10.1101/gr.849004
-
Crooks,G.E., Hon,G., Chandonia,J.M. and Brenner,S.E. (2004) WebLogo: a sequence logo generator. Genome Res., 14, 1188-1190. (Pubitemid 38811555)
-
(2004)
Genome Research
, vol.14
, Issue.6
, pp. 1188-1190
-
-
Crooks, G.E.1
Hon, G.2
Chandonia, J.-M.3
Brenner, S.E.4
-
38
-
-
33845661128
-
A comparative analysis of genome-wide chromatin immunoprecipitation data for mammalian transcription factors
-
Ji,H., Vokes,S.A. and Wong,W.H. (2006) A comparative analysis of genome-wide chromatin immunoprecipitation data for mammalian transcription factors. Nucleic Acids Res., 34, e146.
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Ji, H.1
Vokes, S.A.2
Wong, W.H.3
-
39
-
-
24644462724
-
TileMap: Create chromosomal map of tiling array hybridizations
-
DOI 10.1093/bioinformatics/bti593
-
Ji,H. and Wong,W.H. (2005) TileMap: create chromosomal map of tiling array hybridizations. Bioinformatics, 21, 3629-3636. (Pubitemid 41264098)
-
(2005)
Bioinformatics
, vol.21
, Issue.18
, pp. 3629-3636
-
-
Ji, H.1
Wong, W.H.2
-
40
-
-
53749083993
-
SeqMap: Mapping massive amount of oligonucleotides to the genome
-
Jiang,H. and Wong,W.H. (2008) SeqMap: mapping massive amount of oligonucleotides to the genome. Bioinformatics, 24, 2395-2396.
-
(2008)
Bioinformatics
, vol.24
, pp. 2395-2396
-
-
Jiang, H.1
Wong, W.H.2
-
41
-
-
75649116449
-
Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing
-
Wallerman,O., Motallebipour,M., Enroth,S., Patra,K., Bysani,M.S.R., Komorowski,J. and Wadelius,C. (2009) Molecular interactions between HNF4a, FOXA2 and GABP identified at regulatory DNA elements through ChIP-sequencing. Nucleic Acids Res., 37, 7498-7508.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 7498-7508
-
-
Wallerman, O.1
Motallebipour, M.2
Enroth, S.3
Patra, K.4
Bysani, M.S.R.5
Komorowski, J.6
Wadelius, C.7
-
42
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
-
Huang,D.W., Sherman,B.T. and Lempicki,R.A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc., 4, 44-57.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
43
-
-
0028833051
-
Cooperative formation of high-order oligomers by retinoid X receptors: An unexpected mode of DNA recognition
-
Chen,H. and Privalsky,M.L. (1995) Cooperative formation of high-order oligomers by retinoid X receptors: an unexpected mode of DNA recognition. Proc. Natl Acad. Sci. USA, 92, 422-426.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 422-426
-
-
Chen, H.1
Privalsky, M.L.2
-
44
-
-
35648954161
-
WAF1/CIP1 is a common transcriptional target of retinoid receptors: Pleiotropic regulatory mechanism through Retinoic Acid Receptor (RAR)/Retinoid X Receptor (RXR) heterodimer and RXR/RXR homodimer
-
DOI 10.1074/jbc.M701700200
-
Tanaka,T., Suh,K.S., Lo,A.M. and De Luca,L.M. (2007) p21WAF1/CIP1 is a common transcriptional target of retinoid receptors: pleiotropic regulatory mechanism through retinoic acid receptor (RAR)/retinoid X receptor (RXR) heterodimer and RXR/RXR homodimer. J. Biol. Chem., 282, 29987-29997. (Pubitemid 350035294)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.41
, pp. 29987-29997
-
-
Tanaka, T.1
Suh, K.S.2
Lo, A.M.3
De Luca, L.M.4
-
45
-
-
67449132372
-
Therapeutic potential of "rexinoids" in cancer prevention and treatment
-
Tanaka,T. and De Luca,L.M. (2009) Therapeutic potential of "rexinoids" in cancer prevention and treatment. Cancer Res., 69, 4945-4947.
-
(2009)
Cancer Res.
, vol.69
, pp. 4945-4947
-
-
Tanaka, T.1
De Luca, L.M.2
-
46
-
-
79954992662
-
Extensive chromatin remodelling and establishment of transcription factor 'hotspots'during early adipogenesis
-
Siersbaek,R., Nielsen,R., John,S., Sung,M.H., Baek,S., Loft,A., Hager,G.L. and Mandrup,S. (2011) Extensive chromatin remodelling and establishment of transcription factor 'hotspots'during early adipogenesis. EMBO J., 30, 1459-1472.
-
(2011)
EMBO J.
, vol.30
, pp. 1459-1472
-
-
Siersbaek, R.1
Nielsen, R.2
John, S.3
Sung, M.H.4
Baek, S.5
Loft, A.6
Hager, G.L.7
Mandrup, S.8
-
47
-
-
27244437971
-
Proof of concept for microarray-based detection of DNA-binding oncogenes in cell extracts
-
Egener,T., Roulet,E., Zehnder,M., Bucher,P. and Mermod,N. (2005) Proof of concept for microarray-based detection of DNA-binding oncogenes in cell extracts. Nucleic Acids Res., 33, e79.
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Egener, T.1
Roulet, E.2
Zehnder, M.3
Bucher, P.4
Mermod, N.5
-
48
-
-
77955149398
-
Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver
-
Hoffman,B.G., Robertson,G., Zavaglia,B., Beach,M., Cullum,R., Lee,S., Soukhatcheva,G., Li,L., Wederell,E.D., Thiessen,N. et al. (2010) Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liver. Genome Res., 20, 1037-1051.
-
(2010)
Genome Res.
, vol.20
, pp. 1037-1051
-
-
Hoffman, B.G.1
Robertson, G.2
Zavaglia, B.3
Beach, M.4
Cullum, R.5
Lee, S.6
Soukhatcheva, G.7
Li, L.8
Wederell, E.D.9
Thiessen, N.10
-
49
-
-
55749101777
-
Genome-wide profiling of PPAR:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis
-
Nielsen,R., Pedersen,T.A., Hagenbeek,D., Moulos,P., Siersbaek,R., Megens,E., Denissov,S., Borgesen,M., Francoijs,K.J., Mandrup,S. et al. (2008) Genome-wide profiling of PPAR:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes Dev., 22, 2953-2967.
-
(2008)
Genes Dev.
, vol.22
, pp. 2953-2967
-
-
Nielsen, R.1
Pedersen, T.A.2
Hagenbeek, D.3
Moulos, P.4
Siersbaek, R.5
Megens, E.6
Denissov, S.7
Borgesen, M.8
Francoijs, K.J.9
Mandrup, S.10
-
50
-
-
77957220857
-
Comparative epigenomic analysis of murine and human adipogenesis
-
Mikkelsen,T.S., Xu,Z., Zhang,X., Wang,L., Gimble,J.M., Lander,E.S. and Rosen,E.D. (2010) Comparative epigenomic analysis of murine and human adipogenesis. Cell, 143, 156-169.
-
(2010)
Cell
, vol.143
, pp. 156-169
-
-
Mikkelsen, T.S.1
Xu, Z.2
Zhang, X.3
Wang, L.4
Gimble, J.M.5
Lander, E.S.6
Rosen, E.D.7
-
51
-
-
79251633165
-
Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta)
-
Adhikary,T., Kaddatz,K., Finkernagel,F., Schonbauer,A., Meissner,W., Scharfe,M., Jarek,M., Blocker,H., Muller-Brusselbach,S. and Muller,R. (2011) Genomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta). PLoS One, 6, e16344.
-
(2011)
PLoS One
, vol.6
-
-
Adhikary, T.1
Kaddatz, K.2
Finkernagel, F.3
Schonbauer, A.4
Meissner, W.5
Scharfe, M.6
Jarek, M.7
Blocker, H.8
Muller-Brusselbach, S.9
Muller, R.10
-
52
-
-
77956885532
-
A ChIP-seq defined genome-wide map of vitamin D receptor binding: Associations with disease and evolution
-
Ramagopalan,S.V., Heger,A., Berlanga,A.J., Maugeri,N.J., Lincoln,M.R., Burrell,A., Handunnetthi,L., Handel,A.E., Disanto,G., Orton,S.M. et al. (2010) A ChIP-seq defined genome-wide map of vitamin D receptor binding: associations with disease and evolution. Genome Res., 20, 1352-1360.
-
(2010)
Genome Res.
, vol.20
, pp. 1352-1360
-
-
Ramagopalan, S.V.1
Heger, A.2
Berlanga, A.J.3
Maugeri, N.J.4
Lincoln, M.R.5
Burrell, A.6
Handunnetthi, L.7
Handel, A.E.8
Disanto, G.9
Orton, S.M.10
-
53
-
-
77950605769
-
Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine
-
Thomas,A.M., Hart,S.N., Kong,B., Fang,J., Zhong,X.B. and Guo,G.L. (2010) Genome-wide tissue-specific farnesoid X receptor binding in mouse liver and intestine. Hepatology, 51, 1410-1419.
-
(2010)
Hepatology
, vol.51
, pp. 1410-1419
-
-
Thomas, A.M.1
Hart, S.N.2
Kong, B.3
Fang, J.4
Zhong, X.B.5
Guo, G.L.6
-
54
-
-
77954987308
-
Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1
-
Chong,H.K., Infante,A.M., Seo,Y.K., Jeon,T.I., Zhang,Y., Edwards,P.A., Xie,X. and Osborne,T.F. (2010) Genome-wide interrogation of hepatic FXR reveals an asymmetric IR-1 motif and synergy with LRH-1. Nucleic Acids Res., 38, 6007-6017.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 6007-6017
-
-
Chong, H.K.1
Infante, A.M.2
Seo, Y.K.3
Jeon, T.I.4
Zhang, Y.5
Edwards, P.A.6
Xie, X.7
Osborne, T.F.8
-
55
-
-
78650448030
-
ChIPing the cistrome of PXR in mouse liver
-
Cui,J.Y., Gunewardena,S.S., Rockwell,C.E. and Klaassen,C.D. (2010) ChIPing the cistrome of PXR in mouse liver. Nucleic Acids Res., 38, 7943-7963.
-
(2010)
Nucleic Acids Res.
, vol.38
, pp. 7943-7963
-
-
Cui, J.Y.1
Gunewardena, S.S.2
Rockwell, C.E.3
Klaassen, C.D.4
-
56
-
-
44649117905
-
Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
-
DOI 10.1016/j.cell.2008.04.043, PII S009286740800617X
-
Chen,X., Xu,H., Yuan,P., Fang,F., Huss,M., Vega,V.B., Wong,E., Orlov,Y.L., Zhang,W., Jiang,J. et al. (2008) Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell, 133, 1106-1117. (Pubitemid 351787745)
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1106-1117
-
-
Chen, X.1
Xu, H.2
Yuan, P.3
Fang, F.4
Huss, M.5
Vega, V.B.6
Wong, E.7
Orlov, Y.L.8
Zhang, W.9
Jiang, J.10
Loh, Y.-H.11
Yeo, H.C.12
Yeo, Z.X.13
Narang, V.14
Govindarajan, K.R.15
Leong, B.16
Shahab, A.17
Ruan, Y.18
Bourque, G.19
Sung, W.-K.20
Clarke, N.D.21
Wei, C.-L.22
Ng, H.-H.23
more..
-
57
-
-
75149194937
-
Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer
-
Ross-Innes,C.S., Stark,R., Holmes,K.A., Schmidt,D., Spyrou,C., Russell,R., Massie,C.E., Vowler,S.L., Eldridge,M. and Carroll,J.S. (2010) Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer. Genes Dev., 24, 171-182.
-
(2010)
Genes Dev.
, vol.24
, pp. 171-182
-
-
Ross-Innes, C.S.1
Stark, R.2
Holmes, K.A.3
Schmidt, D.4
Spyrou, C.5
Russell, R.6
Massie, C.E.7
Vowler, S.L.8
Eldridge, M.9
Carroll, J.S.10
-
58
-
-
77953062527
-
Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding
-
Schmidt,D., Wilson,M.D., Ballester,B., Schwalie,P.C., Brown,G.D., Marshall,A., Kutter,C., Watt,S., Martinez-Jimenez,C.P., Mackay,S. et al. (2010) Five-vertebrate ChIP-seq reveals the evolutionary dynamics of transcription factor binding. Science, 328, 1036-1040.
-
(2010)
Science
, vol.328
, pp. 1036-1040
-
-
Schmidt, D.1
Wilson, M.D.2
Ballester, B.3
Schwalie, P.C.4
Brown, G.D.5
Marshall, A.6
Kutter, C.7
Watt, S.8
Martinez-Jimenez, C.P.9
Mackay, S.10
-
59
-
-
77952567987
-
Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities
-
Heinz,S., Benner,C., Spann,N., Bertolino,E., Lin,Y.C., Laslo,P., Cheng,J.X., Murre,C., Singh,H. and Glass,C.K. (2010) Simple combinations of lineage-determining transcription factors prime cis-regulatory elements required for macrophage and B cell identities. Mol. Cell, 38, 576-589.
-
(2010)
Mol. Cell
, vol.38
, pp. 576-589
-
-
Heinz, S.1
Benner, C.2
Spann, N.3
Bertolino, E.4
Lin, Y.C.5
Laslo, P.6
Cheng, J.X.7
Murre, C.8
Singh, H.9
Glass, C.K.10
-
60
-
-
75349088911
-
The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells
-
Heng,J.-C.D., Feng,B., Han,J., Jiang,J., Kraus,P., Ng,J.-H., Orlov,Y.L., Huss,M., Yang,L., Lufkin,T. et al. (2010) The nuclear receptor Nr5a2 can replace Oct4 in the reprogramming of murine somatic cells to pluripotent cells. Cell Stem Cell, 6, 167-174.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 167-174
-
-
Heng, J.-C.D.1
Feng, B.2
Han, J.3
Jiang, J.4
Kraus, P.5
Ng, J.-H.6
Orlov, Y.L.7
Huss, M.8
Yang, L.9
Lufkin, T.10
-
61
-
-
79952529158
-
A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism
-
Feng,D., Liu,T., Sun,Z., Bugge,A., Mullican,S.E., Alenghat,T., Liu,X.S. and Lazar,M.A. (2011) A circadian rhythm orchestrated by histone deacetylase 3 controls hepatic lipid metabolism. Science, 331, 1315-1319.
-
(2011)
Science
, vol.331
, pp. 1315-1319
-
-
Feng, D.1
Liu, T.2
Sun, Z.3
Bugge, A.4
Mullican, S.E.5
Alenghat, T.6
Liu, X.S.7
Lazar, M.A.8
-
62
-
-
77952331646
-
Propagation of adipogenic signals through an epigenomic transition state
-
Steger,D.J., Grant,G.R., Schupp,M., Tomaru,T., Lefterova,M.I., Schug,J., Manduchi,E., Stoeckert,C.J. and Lazar,M.A. (2010) Propagation of adipogenic signals through an epigenomic transition state. Genes Dev., 24, 1035-1044.
-
(2010)
Genes Dev.
, vol.24
, pp. 1035-1044
-
-
Steger, D.J.1
Grant, G.R.2
Schupp, M.3
Tomaru, T.4
Lefterova, M.I.5
Schug, J.6
Manduchi, E.7
Stoeckert, C.J.8
Lazar, M.A.9
-
63
-
-
73249130316
-
Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation
-
Reddy,T.E., Pauli,F., Sprouse,R.O., Neff,N.F., Newberry,K.M., Garabedian,M.J. and Myers,R.M. (2009) Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation. Genome Res., 19, 2163-2171.
-
(2009)
Genome Res.
, vol.19
, pp. 2163-2171
-
-
Reddy, T.E.1
Pauli, F.2
Sprouse, R.O.3
Neff, N.F.4
Newberry, K.M.5
Garabedian, M.J.6
Myers, R.M.7
-
64
-
-
1842324170
-
A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression
-
DOI 10.1073/pnas.84.22.7871
-
Strahle,U., Klock,G. and Schutz,G. (1987) A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression. Proc. Natl Acad. Sci. USA, 84, 7871-7875. (Pubitemid 17162809)
-
(1987)
Proceedings of the National Academy of Sciences of the United States of America
, vol.84
, Issue.22
, pp. 7871-7875
-
-
Strahle, U.1
Klock, G.2
Schutz, G.3
-
65
-
-
0028359720
-
Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region
-
DOI 10.1006/jmbi.1994.1405
-
La Baer,J. and Yamamoto,K.R. (1994) Analysis of the DNA-binding affinity, sequence specificity and context dependence of the glucocorticoid receptor zinc finger region. J. Mol. Biol., 239, 664-688. (Pubitemid 24202391)
-
(1994)
Journal of Molecular Biology
, vol.239
, Issue.5
, pp. 664-688
-
-
La, B.J.1
Yamamoto, K.R.2
-
66
-
-
0029044997
-
Structural determinants of nuclear receptor assembly on DNA direct repeats
-
Rastinejad,F., Perlmann,T., Evans,R.M. and Sigler,P.B. (1995) Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature, 375, 203-211.
-
(1995)
Nature
, vol.375
, pp. 203-211
-
-
Rastinejad, F.1
Perlmann, T.2
Evans, R.M.3
Sigler, P.B.4
-
67
-
-
57749119545
-
Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product
-
Lu,P., Rha,G.B., Melikishvili,M., Wu,G., Adkins,B.C., Fried,M.G. and Chi,Y.I. (2008) Structural basis of natural promoter recognition by a unique nuclear receptor, HNF4alpha. Diabetes gene product. J. Biol. Chem., 283, 33685-33697.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 33685-33697
-
-
Lu, P.1
Rha, G.B.2
Melikishvili, M.3
Wu, G.4
Adkins, B.C.5
Fried, M.G.6
Chi, Y.I.7
-
68
-
-
20444475700
-
Role of regulatory F-domain in hepatocyte nuclear factor-4alpha ligand specificity
-
DOI 10.1074/jbc.M405906200
-
Petrescu,A.D., Hertz,R., Bar-Tana,J., Schroeder,F. and Kier,A.B. (2005) Role of regulatory F-domain in hepatocyte nuclear factor-4alpha ligand specificity. J. Biol. Chem., 280, 16714-16727. (Pubitemid 41389129)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 16714-16727
-
-
Petrescu, A.D.1
Hertz, R.2
Bar-Tana, J.3
Schroeder, F.4
Kier, A.B.5
-
69
-
-
0347695020
-
Physical and Functional Interaction of Acyl-CoA-binding Protein with Hepatocyte Nuclear Factor-4alpha
-
DOI 10.1074/jbc.M303858200
-
Petrescu,A.D., Payne,H.R., Boedecker,A., Chao,H., Hertz,R., Bar-Tana,J., Schroeder,F. and Kier,A.B. (2003) Physical and functional interaction of Acyl-CoA-binding protein with hepatocyte nuclear factor-4 alpha. J. Biol. Chem., 278, 51813-51824. (Pubitemid 38020428)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.51
, pp. 51813-51824
-
-
Petrescu, A.D.1
Payne, H.R.2
Boedecker, A.3
Chao, H.4
Hertz, R.5
Bar-Tana, J.6
Schroeder, F.7
Kier, A.B.8
-
70
-
-
0032473950
-
Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4alpha
-
DOI 10.1038/33185
-
Hertz,R., Magenheim,J., Berman,I. and Bar-Tana,J. (1998) Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4alpha. Nature, 392, 512-516. (Pubitemid 28168984)
-
(1998)
Nature
, vol.392
, Issue.6675
, pp. 512-516
-
-
Hertz, R.1
Magenheim, J.2
Berman, I.3
Bar-Tana, J.4
-
71
-
-
0033636892
-
Acetylation regulates transcription factor activity at multiple levels
-
Soutoglou,E., Katrakili,N. and Talianidis,I. (2000) Acetylation regulates transcription factor activity at multiple levels. Mol. Cell, 5, 745-751.
-
(2000)
Mol. Cell
, vol.5
, pp. 745-751
-
-
Soutoglou, E.1
Katrakili, N.2
Talianidis, I.3
-
72
-
-
0028816031
-
The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids
-
Hall,R.K., Sladek,F.M. and Granner,D.K. (1995) The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids. Proc. Natl Acad. Sci. USA, 92, 412-416.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 412-416
-
-
Hall, R.K.1
Sladek, F.M.2
Granner, D.K.3
-
73
-
-
77149148756
-
Regulation of cellular metabolism by protein lysine acetylation
-
Zhao,S., Xu,W., Jiang,W., Yu,W., Lin,Y., Zhang,T., Yao,J., Zhou,L., Zeng,Y., Li,H. et al. (2010) Regulation of cellular metabolism by protein lysine acetylation. Science, 327, 1000-1004.
-
(2010)
Science
, vol.327
, pp. 1000-1004
-
-
Zhao, S.1
Xu, W.2
Jiang, W.3
Yu, W.4
Lin, Y.5
Zhang, T.6
Yao, J.7
Zhou, L.8
Zeng, Y.9
Li, H.10
-
74
-
-
0027202156
-
Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers
-
Kurokawa,R., Yu,V.C., Naar,A., Kyakumoto,S., Han,Z., Silverman,S., Rosenfeld,M.G. and Glass,C.K. (1993) Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev., 7, 1423-1435. (Pubitemid 23210890)
-
(1993)
Genes and Development
, vol.7
, Issue.7 B
, pp. 1423-1435
-
-
Kurokawa, R.1
Yu, V.C.2
Naar, A.3
Kyakumoto, S.4
Han, Z.5
Silverman, S.6
Rosenfeld, M.G.7
Glass, C.K.8
-
75
-
-
0027237598
-
Determinants for selective RAR and TR recognition of direct repeat HREs
-
Perlmann,T., Rangarajan,P.N., Umesono,K. and Evans,R.M. (1993) Determinants for selective RAR and TR recognition of direct repeat HREs. Genes Dev., 7, 1411-1422. (Pubitemid 23210889)
-
(1993)
Genes and Development
, vol.7
, Issue.7 B
, pp. 1411-1422
-
-
Perlmann, T.1
Rangarajan, P.N.2
Umesono, K.3
Evans, R.M.4
-
76
-
-
0028294902
-
Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements
-
Zechel,C., Shen,X.Q., Chambon,P. and Gronemeyer,H. (1994) Dimerization interfaces formed between the DNA binding domains determine the cooperative binding of RXR/RAR and RXR/TR heterodimers to DR5 and DR4 elements. EMBO J., 13, 1414-1424. (Pubitemid 24090223)
-
(1994)
EMBO Journal
, vol.13
, Issue.6
, pp. 1414-1424
-
-
Zechel, C.1
Shen, X.-Q.2
Chambon, P.3
Gronemeyer, H.4
-
78
-
-
79955581636
-
Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings
-
Rochel,N., Ciesielski,F., Godet,J., Moman,E., Roessle,M., Peluso-Iltis,C., Moulin,M., Haertlein,M., Callow,P., Mely,Y. et al. (2011) Common architecture of nuclear receptor heterodimers on DNA direct repeat elements with different spacings. Nat. Struct. Mol. Biol., 18, 564-570.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 564-570
-
-
Rochel, N.1
Ciesielski, F.2
Godet, J.3
Moman, E.4
Roessle, M.5
Peluso-Iltis, C.6
Moulin, M.7
Haertlein, M.8
Callow, P.9
Mely, Y.10
-
79
-
-
0028122988
-
Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding
-
DOI 10.1038/371528a0
-
Kurokawa,R., DiRenzo,J., Boehm,M., Sugarman,J., Gloss,B., Rosenfeld,M.G., Heyman,R.A. and Glass,C.K. (1994) Regulation of retinoid signalling by receptor polarity and allosteric control of ligand binding. Nature, 371, 528-531. (Pubitemid 24306612)
-
(1994)
Nature
, vol.371
, Issue.6497
, pp. 528-531
-
-
Kurokawa, R.1
DiRenzo, J.2
Boehm, M.3
Sugarman, J.4
Gloss, B.5
Rosenfeld, M.G.6
Heyman, R.A.7
Glass, C.K.8
-
80
-
-
0029154931
-
Polarity-specific activities of retinoic acid receptors determined by a co-repressor
-
Kurokawa,R., Soderstrom,M., Horlein,A., Halachmi,S., Brown,M., Rosenfeld,M.G. and Glass,C.K. (1995) Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature, 377, 451-454.
-
(1995)
Nature
, vol.377
, pp. 451-454
-
-
Kurokawa, R.1
Soderstrom, M.2
Horlein, A.3
Halachmi, S.4
Brown, M.5
Rosenfeld, M.G.6
Glass, C.K.7
-
81
-
-
0029002298
-
Unique response pathways are established by allosteric interactions among nuclear hormone receptors
-
Forman,B.M., Umesono,K., Chen,J. and Evans,R.M. (1995) Unique response pathways are established by allosteric interactions among nuclear hormone receptors. Cell, 81, 541-550.
-
(1995)
Cell
, vol.81
, pp. 541-550
-
-
Forman, B.M.1
Umesono, K.2
Chen, J.3
Evans, R.M.4
-
82
-
-
56749130032
-
Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA
-
Chandra,V., Huang,P., Hamuro,Y., Raghuram,S., Wang,Y., Burris,T.P. and Rastinejad,F. (2008) Structure of the intact PPAR-gamma-RXR- nuclear receptor complex on DNA. Nature, 456, 350-356.
-
(2008)
Nature
, vol.456
, pp. 350-356
-
-
Chandra, V.1
Huang, P.2
Hamuro, Y.3
Raghuram, S.4
Wang, Y.5
Burris, T.P.6
Rastinejad, F.7
-
83
-
-
8544256355
-
Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4
-
DOI 10.1074/jbc.M404255200
-
Hirokane,H., Nakahara,M., Tachibana,S., Shimizu,M. and Sato,R. (2004) Bile acid reduces the secretion of very low density lipoprotein by repressing microsomal triglyceride transfer protein gene expression mediated by hepatocyte nuclear factor-4. J. Biol. Chem., 279, 45685-45692. (Pubitemid 39491557)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.44
, pp. 45685-45692
-
-
Hirokane, H.1
Nakahara, M.2
Tachibana, S.3
Shimizu, M.4
Sato, R.5
-
84
-
-
0036906591
-
Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription
-
DOI 10.1194/jlr.M200386-JLR200
-
Raspe,E., Duez,H., Mansen,A., Fontaine,C., Fievet,C., Fruchart,J.C., Vennstrom,B. and Staels,B. (2002) Identification of Rev-erbalpha as a physiological repressor of apoC-III gene transcription. J. Lipid Res., 43, 2172-2179. (Pubitemid 35471086)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.12
, pp. 2172-2179
-
-
Raspe, E.1
Duez, H.2
Mansen, A.3
Fontaine, C.4
Fievet, C.5
Fruchart, J.-C.6
Vennstrom, B.7
Staels, B.8
-
85
-
-
34447556690
-
Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis
-
DOI 10.1177/0748730407302461
-
Noshiro,M., Usui,E., Kawamoto,T., Kubo,H., Fujimoto,K., Furukawa,M., Honma,S., Makishima,M., Honma,K. and Kato,Y. (2007) Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis. J. Biol. Rhythms, 22, 299-311. (Pubitemid 47077307)
-
(2007)
Journal of Biological Rhythms
, vol.22
, Issue.4
, pp. 299-311
-
-
Noshiro, M.1
Usui, E.2
Kawamoto, T.3
Kubo, H.4
Fujimoto, K.5
Furukawa, M.6
Honma, S.7
Makishima, M.8
Honma, K.-I.9
Kato, Y.10
-
86
-
-
0037327003
-
The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4
-
DOI 10.1038/nm815
-
Tirona,R.G., Lee,W., Leake,B.F., Lan,L.B., Cline,C.B., Lamba,V., Parviz,F., Duncan,S.A., Inoue,Y., Gonzalez,F.J. et al. (2003) The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4. Nat. Med., 9, 220-224. (Pubitemid 36227725)
-
(2003)
Nature Medicine
, vol.9
, Issue.2
, pp. 220-224
-
-
Tirona, R.G.1
Lee, W.2
Leake, B.F.3
Lan, L.-B.4
Brimer, C.C.5
Lamba, V.6
Parviz, F.7
Duncan, S.A.8
Inoue, Y.9
Gonzalez, F.J.10
Schuetz, E.G.11
Kim, R.B.12
-
87
-
-
34548301080
-
The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase
-
DOI 10.1210/me.2007-0002
-
Echchgadda,I., Song,C.S., Oh,T., Ahmed,M., De La Cruz,I.J. and Chatterjee,B. (2007) The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase. Mol. Endocrinol., 21, 2099-2111. (Pubitemid 47347375)
-
(2007)
Molecular Endocrinology
, vol.21
, Issue.9
, pp. 2099-2111
-
-
Echchgadda, I.1
Song, C.S.2
Oh, T.3
Ahmed, M.4
De La, C.I.J.5
Chatterjee, B.6
-
88
-
-
0024356431
-
Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor
-
DOI 10.1016/0092-8674(89)90050-0
-
Danielsen,M., Hinck,L. and Ringold,G.M. (1989) Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor. Cell, 57, 1131-1138. (Pubitemid 19169809)
-
(1989)
Cell
, vol.57
, Issue.7
, pp. 1131-1138
-
-
Danielsen, M.1
Hinck, L.2
Ringold, G.M.3
-
89
-
-
78149390724
-
Protein evolution by molecular tinkering: Diversification of the nuclear receptor superfamily from a ligand-dependent ancestor
-
Bridgham,J.T., Eick,G.N., Larroux,C., Deshpande,K., Harms,M.J., Gauthier,M.E., Ortlund,E.A., Degnan,B.M. and Thornton,J.W. (2010) Protein evolution by molecular tinkering: diversification of the nuclear receptor superfamily from a ligand-dependent ancestor. PLoS Biol, 8, e1000497.
-
(2010)
PLoS Biol
, vol.8
-
-
Bridgham, J.T.1
Eick, G.N.2
Larroux, C.3
Deshpande, K.4
Harms, M.J.5
Gauthier, M.E.6
Ortlund, E.A.7
Degnan, B.M.8
Thornton, J.W.9
-
90
-
-
0027993931
-
Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver
-
DOI 10.1016/0378-1119(94)90079-5
-
Chartier,F.L., Bossu,J.P., Laudet,V., Fruchart,J.C. and Laine,B. (1994) Cloning and sequencing of cDNAs encoding the human hepatocyte nuclear factor 4 indicate the presence of two isoforms in human liver. Gene, 147, 269-272. (Pubitemid 24306343)
-
(1994)
Gene
, vol.147
, Issue.2
, pp. 269-272
-
-
Chartier, F.L.1
Bossu, J.-P.2
Laudet, V.3
Fruchart, J.-C.4
Laine, B.5
-
91
-
-
0034964730
-
Maturity-onset diabetes of the young type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional coactivator
-
DOI 10.1210/me.15.7.1200
-
Eeckhoute,J., Formstecher,P. and Laine,B. (2001) Maturity-onset diabetes of the young Type 1 (MODY1)-associated mutations R154X and E276Q in hepatocyte nuclear factor 4alpha (HNF4alpha) gene impair recruitment of p300, a key transcriptional co-activator. Mol. Endocrinol., 15, 1200-1210. (Pubitemid 32614072)
-
(2001)
Molecular Endocrinology
, vol.15
, Issue.7
, pp. 1200-1210
-
-
Eeckhoute, J.1
Formstecher, P.2
Laine, B.3
-
92
-
-
77949535720
-
Features and development of Coot
-
Emsley,P., Lohkamp,B., Scott,W.G. and Cowtan,K. (2010) Features and development of Coot. Acta Crystallogr. D Biol. Crystallogr., 66, 486-501.
-
(2010)
Acta Crystallogr. D Biol. Crystallogr.
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
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